T4085 |
Paris saponin VII
|
68124-04-9
|
99.83%
|
|
Paris saponin VII (Dioscini) shows inhibitory effects on cell proliferation.
|
T1010 |
Verapamil hydrochloride
|
152-11-4
|
99.79%
|
|
Verapamil hydrochloride (Verapamil HCl) is a calcium channel blocker that is a class IV anti-arrhythmia agent.
|
T1634 |
Glibenclamide
|
10238-21-8
|
99.77%
|
|
Glibenclamide (Glyburide) is an antidiabetic sulfonylurea derivative with actions similar to those of chlorpropamide.
|
T0100L |
Atazanavir
|
198904-31-3
|
99.76%
|
|
Atazanavir (BMS-232632)(BMS-232632) is an highly effective HIV-1 protease inhibitor.
|
T0100 |
Atazanavir sulfate
|
229975-97-7
|
99.67%
|
|
Atazanavir sulfate (BMS-232632 sulfate) is an azapeptide and HIV-PROTEASE INHIBITOR that is used in the treatment of HIV INFECTIONS and AIDS in combination with ...
|
T11578L |
Encequidar mesylate
|
849675-87-2
|
99.67%
|
|
Encequidar mesylate (HM30181A mesylate) is a competitive P-glycoprotein inhibitor.
|
T16339 |
Norverapamil hydrochloride
|
67812-42-4
|
99.63%
|
|
Norverapamil hydrochloride (D591 hydrochloride) ((±)-Norverapamil hydrochloride) is an N-demethylated metabolite of Verapamil and it is an L-type calcium channel...
|
T77575 |
P-gb-IN-1
|
2632874-49-6
|
99.58%
|
|
P-gb-IN-1 is a potent P-glycoprotein (P-gp) inhibitor that exhibits reverse activity by inhibiting P-gp outflow. P-gb-IN-1 has been shown to inhibit P-gp by hydr...
|
T6018 |
Zosuquidar trihydrochloride
|
167465-36-3
|
99.55%
|
|
Zosuquidar trihydrochloride (LY-335979 trihydrochloride) is a potent modulator of P-glycoprotein-mediated multi-drug resistance with Ki of 60 nM. Phase 3.
|
TN1731 |
Hernandezine
|
6681-13-6
|
99.53%
|
|
Hernandezine is an activator of AMPK activator and a selective reversing agent for ABCB1-mediated MDR in cancer cells.
|
T20656 |
Verapamil
|
52-53-9
|
99.53%
|
|
Verapamil (CP-16533-1) is a calcium channel blocker and an orally active and effective inhibitor of P-gp. Verapamil inhibits CYP3A4 and can be used in studies ab...
|
T11071 |
Dofequidar fumarate
|
153653-30-6
|
99.43%
|
|
Dofequidar fumarate (MS-209)(MS-209 fumarate), a quinoline-based compound administered orally, is known for counteracting multidrug resistance (MDR) through the ...
|
T2657 |
Elacridar
|
143664-11-3
|
99.32%
|
|
Elacridar (GG918) (GF120918) is an effective BCRP and P-gp (MDR-1) inhibitor.
|
TN1525 |
Convallatoxin
|
508-75-8
|
99.27%
|
|
Convallatoxin is a natural product
|
T15713 |
Larotaxel
|
156294-36-9
|
99.22%
|
|
Larotaxel (XRP9881) is a taxane analogue that has anticancer activity, exerts its cytotoxic effects by promoting tubulin assembly and stabilizing microtubules, a...
|
TN5118 |
Taxol C
|
153415-45-3
|
99.18%
|
|
Taxol C can reduce interaction with the P-glycoprotein transporter that may allow for increased permeation of taxanes into the brain.
|
T2S0223 |
Isosinensetin
|
17290-70-9
|
99.05%
|
|
1. Isosinensetin (6-Demethoxynobiletin) shows antioxidant and HIV-1 protease inhibiting activities.
|
T8389 |
Trifluoperazine
|
117-89-5
|
99.03%
|
|
Trifluoperazine (trifluoroperazine) is a Dopamine D2 receptor inhibitor(IC50 : 1.2 nM), and Treatment of schizophrenia.
|
T3868 |
Agnuside
|
11027-63-7
|
98.98%
|
|
Agnuside (chasteberry oil) inhibits COX-2 (IC50: 0.026 mg/ml) but exhibits less than 10% inhibition of COX-1 at this concentration. It also inhibits 46.3, 66.8, ...
|
T2799 |
(20S)-Protopanaxadiol
|
30636-90-9
|
98.91%
|
|
(20S)-Protopanaxadiol (20-Epiprotopanaxadiol) (20-Epiprotopanaxadiol), an apoptosis inducer, is an aglycon metabolic derivative of the protopanaxadiol-type ginse...
|