T69146 |
Suksdorfin
|
53023-17-9
|
98%
|
|
Suksdorfin has hypoglycemic effects, promotes adipocyte differentiation and enhances lipocalin production, activates peroxisome proliferator-activated receptor g...
|
T15243 |
Ertiprotafib
|
251303-04-5
|
98%
|
|
Ertiprotafib is a PTP1B, IkB kinase β (IKK-β), and a dual PPARα and PPARβ agonist inhibitor ( IC50s: 1.6 μM for PTP1B, 400 nM for IKK-β, an EC50 of ~1 μM for PPA...
|
TN5091 |
Tagitinin A
|
59979-61-2
|
98%
|
|
Tagitinin A is a plant insecticidal compound, it has phytotoxic activity, it shows significant inhibition of wheat coleoptile growth, seed germination, and the g...
|
T27519 |
GW 9578
|
247923-29-1
|
98%
|
|
GW 9578 is a selective and potent PPARα agonist with potent lipid-lowering activity for the study of psoriasis, arthritis, alopecia, asthma and type I diabetes.
|
TN2228 |
Soyasaponin Aa
|
117230-33-8
|
98%
|
|
Soyasaponin Aa and soyasaponin Ab dose-dependently markedly inhibit adipocyte differentiation and expression of various adipogenic marker genes, through the down...
|
TN4094 |
Gallocatechin gallate
|
5127-64-0
|
98%
|
|
Gallocatechin gallate has strong antioxidative, and anti-obesity activities, it inhibits 3T3-L1 differentiation and lipopolysaccharide induced inflammation throu...
|
TN5149 |
Tirotundin
|
56377-67-4
|
98%
|
|
Tirotundin is a PPARα/γ dual agonist, it exerts anti-diabetic effect through PPARγ pathway. It shows anti-inflammatory activity, it inhibits inhibit the activati...
|
TN4860 |
Pueroside B
|
100692-54-4
|
98%
|
|
Pueroside B may can treat coronary heart disease, it can interact with two or more targets[peroxisome proliferator activated receptor γ (PPAR-γ), angiotensin-con...
|
TN3152 |
6-Acetonyldihydrochelerythrine
|
22864-92-2
|
98%
|
|
6-Acetonyldihydrochelerythrine exhibits significant antioxidant activities, it exhibits significant anti-HIV activity in H9 lymphocytes with EC50 and TI (Therape...
|
T14356 |
AVE-8134
|
304025-09-0
|
98%
|
|
AVE-8134 is an agonist of PPARα. For human and rodent PPARα receptor, the EC50 values are 100 and 3000 nM, respectively.
|
TN2535 |
1-Hydroxy-2-oxopomolic acid
|
217466-37-0
|
98%
|
|
1β-Hydroxy-2-oxopomolic acid inhibits adipocyte differentiation through downregulation of various adipocytokines by blocking PPARγ and C/EBPα expression.
|
T10327 |
Ankaflavin
|
50980-32-0
|
98%
|
|
Ankaflavin is isolated from Monascus-Fermented red rice and is a PPARγ agonist with anti-inflammatory activity. It shows the selective cytotoxic effect and induc...
|
T12529 |
Pparδ agonist 2
|
870884-12-1
|
98%
|
|
Pparδ agonist 2 is an agonist of PPARδ.
|
TN1703 |
Glycyrin
|
66056-18-6
|
98%
|
|
Glycyrin, one of the main PPAR-gamma ligands of licorice, can significantly decrease the blood glucose levels of genetically diabetic KK-A(y) mice.
|
T11754 |
Ketorolac-d5
|
1215767-66-0
|
98%
|
|
Ketorolac D5, a deuterium-labeled version of Ketorolac, is a non-steroidal anti-inflammatory agent that functions as a nonselective COX inhibitor. It exhibits IC...
|
T15748 |
LG100754
|
180713-37-5
|
98%
|
|
LG100754 (UVI 2112) is an insulin sensitizer that functions through RXR. LG100754 is an RXR dimer modulator. LG100754 acts as an RXR: RXR homodimer antagonist, b...
|
TQ0272 |
Balaglitazone
|
199113-98-9
|
98%
|
|
Balaglitazone is a selective partial agonist for PPARγ (EC50: 1.351 μM for human PPARγ).
|
T17189 |
U-46619
|
56985-40-1
|
98%
|
|
U-46619 is an effective thromboxane A2 (TXA2) agonist and a thromboxane A2 analog (endoperoxide), capable of inducing contraction in the aortic smooth muscle (SM...
|
TN2641 |
15-Methoxypinusolidic acid
|
769928-72-5
|
98%
|
|
15-Methoxypinusolidic acid has anti-inflammatory effects, it inhibits LPS-induced iNOS expression and NO production, independent on MAPK and NF-kappaB. 15-Methox...
|
T10506 |
PPAR agonist 1
|
539813-69-9
|
98%
|
|
PPAR agonist 1 is an agonist of PPAR α/γ, used for reducing blood glucose, lipid levels, reducing body weight, and lowering cholesterol.
|