Opioid Receptor

Opioid receptors belong to the large superfamily of seven transmembrane-spanning (7TM) G protein-coupled receptors (GPCRs). As a class, GPCRs are of fundamental physiological importance mediating the actions of the majority of known neurotransmitters and hormones.

Cat. No.	Product name	CAS No.	Purity
T14835	BTRX-335140	2244614-14-8	98.45%
T14835	BTRX-335140 (CYM-53093) is a potent and selective, orally active κ opioid receptor (KOR) antagonist, has antagonist activity for κOR, μOR and δOR with IC50 value...
T26869	BMS-986122	313669-88-4	98.42%
T26869	BMS-986122 (BMS 986122) is a positive allosteric modulator of μ-opioid receptors that increases β-arrestin recruitment stimulated by endomorphin 1 in U2OS-OPRM1 ...
T10593	BPR1M97	2059904-66-2	98.13%
T10593	BPR1M97 is a mu opioid receptor (MOP) and neuropeptide-orphin FQ (NOP) receptor agonist with blood-brain barrier permeability and potency, with Kis values of 1.8...
TP1367	[D-Ala2]leucine-enkephalin	64963-01-5	98.06%
TP1367	[D-Ala2]-Leucine enkephalin is a delta opioid agonist used to study the signaling pathway of delta opioid receptors.
TP1885L1	[(pF)Phe4]Nociceptin(1-13)NH2 acetate	TP1885L1	98.03%
TP1885L1	[(pF)Phe4]Nociceptin(1-13)NH2 acetate is a selective agonist of NOP receptor with a pKi of 10.68 and a pEC50 of 9.31. [(pF)Phe4]Nociceptin(1-13)NH2 acetate displ...
T11909	LY2444296	1346133-11-6	98.03%
T11909	LY2444296 (FP3FBZ) is an orally active and selective antagonist of kappa opioid receptor(Ki = 1 nM).
T27667	JNJ-20788560	825649-28-3	98%
T27667	JNJ-20788560 is a delta opioid receptor (DOR) agonist with analgesic activity. It is more selective for DOR than for mu opioid receptors (MOR).
T7218	Endomorphin 2	141801-26-5	98%
T7218	Endomorphins-2 (EM-2) could decrease both the frequency and amplitude of the sEPSC of the motoneurons in lamina IX, which was reversed by the MOR antagonist CTOP...
T7211	Tyr-Gly-Gly-Phe-Met-OH	58569-55-4	98%
T7211	Tyr-Gly-Gly-Phe-Met-OH (Met-Enkephalin), is a naturally occurring, endogenous opioid peptide that inhibits tumor growth via binding to the opioid receptor.
TP1793L	Nociceptin (1-13) amide TFA	TP1793L	98%
TP1793L	Nociceptin (1-13), amide is a potent agonist Opioid receptor-like1 (ORL1) receptor with a pEC50 of 7.9 for mouse vas deferens and a Ki of 0.75 nM for binding to ...
T37610	AT-121	2099681-31-7	97.95%
T37610	AT-121 is a dual μ-opioid and neuropeptide receptor partial agonist (Kis 16.49 and 3.67 nM, respectively). It stimulates [35S]GTPγS binding to cell membranes exp...
T12320	ORL1 antagonist 1	1174985-59-1	97.87%
T12320	ORL1 antagonist 1 is an o antagonist of pioid receptor-like 1 (ORL1) (IC50 of 61 nM).
TQ0091	LY2795050	1346133-08-1	97.77%
TQ0091	LY2795050 is a novel specific κ-Opioid Receptor antagonist (IC50: 0.72 nM).
T39529	AT-121 hydrochloride	2099681-71-5	97.28%
T39529	AT-121 hydrochloride is a dual agonist of nociception and mu opioid receptor with Ki values of 3.67 and 16.49 nM, respectively.AT-121 hydrochloride is a safe, no...
T2870	Matrine	519-02-8	97.16%
T2870	Matrine (Vegard), an alkaloid isolated from the Sophora genus, acts as a kappa opioid receptor agonist.
T38193L	β-Endorphin (1-27) (human) acetate		96.52%
T38193L	β-Endorphin (1-27) (human) acetate, existing in the hypophysis cerebri and hypothalamus, exhibits antinociception activity. β-Endorphin (1-27) (human) acetate is...
TP2105L	UFP-101 acetate	TP2105L	95.92%
TP2105L	UFP-101 acetate is a selective and competitive antagonist of the NOP receptor (pKi = 10.24) with >3000-fold selectivity over δ, μ, and κ opioid receptors.
TP1882L1	Orphanin FQ(1-11) acetate(178249-41-7 free base)	TP1882L1	95.54%
TP1882L1	Peptide fragment containing amino acids 1-11 of Nociceptin. Potent agonist of the ORL1/KOR-3 receptor (Ki = 55 nM); displays no affinity for opioid receptors, in...
T22752L	(D-Ser2)-Leu-Enkephalin-Thr	T22752L	94.17%
T22752L	(D-Ser2)-Leu-Enkephalin-Thr is a delta selective agent of opioid receptor and shows analgesic effects.
T8455	Spinorphin	137201-62-8	100%
T8455	Spinorphin is a heptapeptide, and is a potent enkephalin-degrading enzymes inhibitor.