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Neurokinin receptor

The tachykinin receptor 1 (TACR1) also known as neurokinin 1 receptor (NK1R) or substance P receptor (SPR) is a G protein coupled receptor found in the central nervous system and peripheral nervous system. The endogenous ligand for this receptor is Substance P, although it has some affinity for other tachykinins.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
TP1738L Kassinin acetate(63968-82-1 free base) TP1738L 95.81%
Kassinin acetate(63968-82-1 free base)
Kassinin acetate is a peptide derived from the Kassina frog. It belongs to tachykinin family of neuropeptides.
T7633 Senktide 106128-89-6 100%
Senktide
Senktide is an agonist of tachykinin NK3 receptor.
TP1369L [Sar9,Met(O2)11]-Substance P acetate TP1369L 100%
[Sar9,Met(O2)11]-Substance P acetate
[Sar9,Met(O2)11]-Substance P acetate is a tachykinin NK1 receptor selective agonist. [Sar9,Met(O2)11]-Substance P acetate is a selective tachykinin NK1 receptor ...
TP1385 Neurokinin A(4-10) TFA(97559-35-8 free base) TP1385 100%
Neurokinin A(4-10) TFA(97559-35-8 free base)
Neurokinin A(4-10) TFA(97559-35-8 free base) is a tachykinin NK2 receptor agonist[1].
T8235 L-732138 148451-96-1 100%
L-732138
L-732138 is a potent and competitive antagonist of neurokinin-1 (NK-1) receptor(IC50 : 2.3 nM)
T7828 [Sar9,Met(O2)11]-Substance P 110880-55-2 100%
[Sar9,Met(O2)11]-Substance P
[Sar9,Met(O2)11]-Substance P (NA) is an agonist of NK1 receptor.
TP1008 Neurokinin A 86933-74-6 100%
Neurokinin A
Neurokinin A (NKA), formerly known as Substance K, is a neurologically active peptide translated from the pre-protachykinin gene.
TP1883 [Lys5,MeLeu9,Nle10]-NKA(4-10) 137565-28-7 100%
[Lys5,MeLeu9,Nle10]-NKA(4-10)
Highy selective and potent NK2 receptor agonist (IC50 = 6.1 nM). Induces contraction of the rat fundus and bladder (EC50 values are 117 and 10 nM respectively).
T12000 MEN11467 214487-46-4 100%
MEN11467
MEN11467 is a novel, orally available, potent and selective peptidomimetic tachykinin NK 1 receptor antagonist for the study of acute colon cancer.
T7554 Substance P (7-11) 51165-05-0 100%
Substance P (7-11)
Substance P (7-11) (Substance P 7-11(TFA)) is a C-terminal fragment of Substance P .
T69140 Burapitant 537034-22-3 100%
Burapitant
Burapitant (SSR 240600) is a novel non-peptide tachykinin neurokinin 1 (NK) receptor antagonist with anti-coke oven and antidepressant activity.
TP1086 Men 10376 TFA(135306-85-3,free) TP1086
Men 10376 TFA(135306-85-3,free)
Men 10376 TFA(135306-85-3,free) (Neurokinin-2 receptor antagonist TFA) is an effective and selective tachykinin nk-2 receptor antagonist with a K I value of 4.4 ...
T3716 Rolapitant 552292-08-7 98%
Rolapitant
Rolapitant (SCH619734) Hydrochloride is the hydrochloride salt form of rolapitant, an orally bioavailable, centrally-acting, selective, neurokinin 1 receptor (NK...
TP1851L Scyliorhinin II acetate TP1851L 98%
Scyliorhinin II acetate
Scyliorhinin II acetate is a selective agonist of the neurokinin-3 (NK3) receptor (Ki = 2.5 nM) in rat cerebral cortex.
T19518L Physalaemin acetate 98%
Physalaemin acetate
Physalaemin acetate is a non-mammalian tachykinin with high affinity when binding selectively to neurokinin-1 (NK1) receptor.
T20413L Spantide acetate T20413L 98%
Spantide acetate
Spantide acetate is a selective antagonist of NK1 receptor with Kis of 230 nM and 8150 nM for NK1 and NK2.
T24697L R 396 acetate 98%
R 396 acetate
R 396 acetate is an NK-2 Tachykinin Receptor Antagonist.
T38144 Elinzanetant 929046-33-3 98%
Elinzanetant
Elinzanetant is a dual antagonist of neurokinin (NK) receptors 1 and 3 and modulates reproductive hormone secretion.
T17156 Tradipitant 622370-35-8 98%
Tradipitant
Tradipitant (VLY-686) is an antagonist of neurokinin-1.
T24446L MEN 10207 acetate 98%
MEN 10207 acetate
MEN 10207 acetate is a selective antagonist for NK-2 tachykinin receptor.
Kassinin acetate(63968-82-1 free base)
TP1738L
Kassinin acetate is a peptide derived from the Kassina frog. It belongs to tachykinin family of neuropeptides.
Senktide
T7633
Senktide is an agonist of tachykinin NK3 receptor.
[Sar9,Met(O2)11]-Substance P acetate
TP1369L
[Sar9,Met(O2)11]-Substance P acetate is a tachykinin NK1 receptor selective agonist. [Sar9,Met(O2)11]-Substance P acetate is a selective tachykinin NK1 receptor ...
Neurokinin A(4-10) TFA(97559-35-8 free base)
TP1385
Neurokinin A(4-10) TFA(97559-35-8 free base) is a tachykinin NK2 receptor agonist[1].
L-732138
T8235
L-732138 is a potent and competitive antagonist of neurokinin-1 (NK-1) receptor(IC50 : 2.3 nM)
[Sar9,Met(O2)11]-Substance P
T7828
[Sar9,Met(O2)11]-Substance P (NA) is an agonist of NK1 receptor.
Neurokinin A
TP1008
Neurokinin A (NKA), formerly known as Substance K, is a neurologically active peptide translated from the pre-protachykinin gene.
[Lys5,MeLeu9,Nle10]-NKA(4-10)
TP1883
Highy selective and potent NK2 receptor agonist (IC50 = 6.1 nM). Induces contraction of the rat fundus and bladder (EC50 values are 117 and 10 nM respectively).
MEN11467
T12000
MEN11467 is a novel, orally available, potent and selective peptidomimetic tachykinin NK 1 receptor antagonist for the study of acute colon cancer.
Substance P (7-11)
T7554
Substance P (7-11) (Substance P 7-11(TFA)) is a C-terminal fragment of Substance P .
Burapitant
T69140
Burapitant (SSR 240600) is a novel non-peptide tachykinin neurokinin 1 (NK) receptor antagonist with anti-coke oven and antidepressant activity.
Men 10376 TFA(135306-85-3,free)
TP1086
Men 10376 TFA(135306-85-3,free) (Neurokinin-2 receptor antagonist TFA) is an effective and selective tachykinin nk-2 receptor antagonist with a K I value of 4.4 ...
Rolapitant
T3716
Rolapitant (SCH619734) Hydrochloride is the hydrochloride salt form of rolapitant, an orally bioavailable, centrally-acting, selective, neurokinin 1 receptor (NK...
Scyliorhinin II acetate
TP1851L
Scyliorhinin II acetate is a selective agonist of the neurokinin-3 (NK3) receptor (Ki = 2.5 nM) in rat cerebral cortex.
Physalaemin acetate
T19518L
Physalaemin acetate is a non-mammalian tachykinin with high affinity when binding selectively to neurokinin-1 (NK1) receptor.
Spantide acetate
T20413L
Spantide acetate is a selective antagonist of NK1 receptor with Kis of 230 nM and 8150 nM for NK1 and NK2.
R 396 acetate
T24697L
R 396 acetate is an NK-2 Tachykinin Receptor Antagonist.
Elinzanetant
T38144
Elinzanetant is a dual antagonist of neurokinin (NK) receptors 1 and 3 and modulates reproductive hormone secretion.
Tradipitant
T17156
Tradipitant (VLY-686) is an antagonist of neurokinin-1.
MEN 10207 acetate
T24446L
MEN 10207 acetate is a selective antagonist for NK-2 tachykinin receptor.
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TargetMol