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NADPH

Nicotinamide adenine dinucleotide phosphate, abbreviated NADP+ or, in older notation, TPN (triphosphopyridine nucleotide), is a cofactor used in anabolic reactions, such as the Calvin cycle and lipid and nucleic acid syntheses, which require NADPH as a reducing agent. It is used by all forms of cellular life.NADPH is the reduced form of NADP+. NADP+ differs from NAD+ in the presence of an additional phosphate group on the 2' position of the ribose ring that carries the adenine moiety. This extra phosphate is added by NAD+ kinase and removed by NADP+ phosphatase.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T0441 Pasiniazid 2066-89-9 98%
Pasiniazid
Pasiniazid (Paraniazide) is an anti-TB and anti-leprosy drug.
T7406 AKR1C3-IN-1 327092-81-9 98%
AKR1C3-IN-1
AKR1C3-IN-1 is a potent and selective inhibitor of AKR1C3(IC50 of 13 nM).
T7191 Diphenyleneiodonium chloride 4673-26-1 98%
Diphenyleneiodonium chloride
Diphenyleneiodonium chloride (DPI)(DPI) is an irreversible inhibitor of iNOS and eNOS (IC50 values of 50 nM and 0.3 μM, respectively),and displays broad-spectrum...
T4359 VAS2870 722456-31-7 97.49%
VAS2870
VAS2870 is an inhibitor of NADPH oxidase (NOX).
TN2126 Quercetin-3-O-glucose-6''-acetate 54542-51-7 97.48%
Quercetin-3-O-glucose-6''-acetate
Quercetin-3-O-glucose-6''-acetate (6"-O-Acetylisoquercitrin) is an inhibitor of NADPH oxidase. Quercetin-3-O-glucose-6''-acetate has antioxidant activities.
T4529 ASP-9521 1126084-37-4 96.96%
ASP-9521
ASP-9521 is an effective, specific and orally available AKR1C3 inhibitor (IC50: 11 nM, for human).
T7374 2-HBA 131359-24-5 95.01%
2-HBA
2-HBA, a synthetic analog of curcumin, is an indirect inducer of enzymes that catalyze detoxification reactions through the Keap1-Nrf2-ARE pathway.
T67950 S19-1035 100%
S19-1035
S19-1035 is a potent and specific inhibitor of aldo-keto reductase 1C3 (AKR1C3), displaying an inhibitory concentration (IC50) of 3.04 nM. It is primarily utiliz...
T1314 Triclosan 3380-34-5 100%
Triclosan
Triclosan (Irgasan) is an antibacterial and antifungal agent.
T0342 Carvedilol phosphate hemihydrate 610309-89-2 100%
Carvedilol phosphate hemihydrate
Carvedilol phosphate hemihydrate (BM 14190 phosphate hemihydrate) is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent with ...
T38684 AKR1C3-IN-4 1284180-11-5 98%
AKR1C3-IN-4
AKR1C3-IN-4 is a potent and selective inhibitor of aldo-keto reductase 1C3 (AKR1C3) with an IC50 of 0.56 μM. AKR1C3-IN-4 has the potential for castrate resistant...
T39635 Obafistat 2160582-57-8 98%
Obafistat
Obafistat is a potent inhibitor of aldo-keto reductase AKR1C3 with an IC50 of 1.2 nM for human AKR1C3.
T0809 Dicoumarol 66-76-2 98%
Dicoumarol
Dicoumarol (Dicumarol) is a hydroxycoumarin originally isolated from molding sweet-clover hay, with anticoagulant and vitamin K depletion activities. Dicoumarol ...
Pasiniazid
T0441
Pasiniazid (Paraniazide) is an anti-TB and anti-leprosy drug.
AKR1C3-IN-1
T7406
AKR1C3-IN-1 is a potent and selective inhibitor of AKR1C3(IC50 of 13 nM).
Diphenyleneiodonium chloride
T7191
Diphenyleneiodonium chloride (DPI)(DPI) is an irreversible inhibitor of iNOS and eNOS (IC50 values of 50 nM and 0.3 μM, respectively),and displays broad-spectrum...
VAS2870
T4359
VAS2870 is an inhibitor of NADPH oxidase (NOX).
Quercetin-3-O-glucose-6''-acetate
TN2126
Quercetin-3-O-glucose-6''-acetate (6"-O-Acetylisoquercitrin) is an inhibitor of NADPH oxidase. Quercetin-3-O-glucose-6''-acetate has antioxidant activities.
ASP-9521
T4529
ASP-9521 is an effective, specific and orally available AKR1C3 inhibitor (IC50: 11 nM, for human).
2-HBA
T7374
2-HBA, a synthetic analog of curcumin, is an indirect inducer of enzymes that catalyze detoxification reactions through the Keap1-Nrf2-ARE pathway.
S19-1035
T67950
S19-1035 is a potent and specific inhibitor of aldo-keto reductase 1C3 (AKR1C3), displaying an inhibitory concentration (IC50) of 3.04 nM. It is primarily utiliz...
Triclosan
T1314
Triclosan (Irgasan) is an antibacterial and antifungal agent.
Carvedilol phosphate hemihydrate
T0342
Carvedilol phosphate hemihydrate (BM 14190 phosphate hemihydrate) is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent with ...
AKR1C3-IN-4
T38684
AKR1C3-IN-4 is a potent and selective inhibitor of aldo-keto reductase 1C3 (AKR1C3) with an IC50 of 0.56 μM. AKR1C3-IN-4 has the potential for castrate resistant...
Obafistat
T39635
Obafistat is a potent inhibitor of aldo-keto reductase AKR1C3 with an IC50 of 1.2 nM for human AKR1C3.
Dicoumarol
T0809
Dicoumarol (Dicumarol) is a hydroxycoumarin originally isolated from molding sweet-clover hay, with anticoagulant and vitamin K depletion activities. Dicoumarol ...
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TargetMol