TN4160 |
Goniothalamin
|
17303-67-2
|
98%
|
|
Goniothalamin induces apoptosis in various cancer cell lines and has gastroprotective activity.
|
TN4604 |
Myricanone
|
32492-74-3
|
98%
|
|
Myricanone has antioxidant, and anticancer activities, it has apoptosis-promoting ability by triggering caspase activation, and suppression of cell proliferation...
|
T6804 |
Chetomin
|
1403-36-7
|
98%
|
|
Chetomin (BRN0077366) is an inhibitor of HIF-1 by weaken transcription of HIF-1, disrupting the binding of HIF-1α and HIF-2α to p300 at low nanomolar concentrati...
|
T11355 |
Gamitrinib TPP
|
1131626-46-4
|
98%
|
|
Gamitrinib TPP is a mitochondrial targeted HSP90 inhibitor exhibiting potent anti-cancer activity. Additionally, Gamitrinib TPP functions as a mitochondrial matr...
|
T6442 |
CH5138303
|
959763-06-5
|
98%
|
|
CH5138303 is an orally available Hsp90 inhibitor with Kd of 0.48 nM.
|
TN3070 |
4beta-Hydroxywithanolide E
|
54334-04-2
|
98%
|
|
4beta-Hydroxywithanolide E(4bHWE) can inhibit the growth of colon cancer monolayer and spheroid cultures, it assert its anti-tumor activity in carcinogenic progr...
|
T11356 |
Gamitrinib TPP hexafluorophosphate
|
1131626-47-5
|
98%
|
|
Gamitrinib TPP hexafluorophosphate is a potent HSP90 inhibitor that specifically targets the mitochondria, demonstrating notable anti-cancer activity. It functio...
|
T15671 |
KU-32
|
956498-70-7
|
98%
|
|
KU-32 is a novel and novobiocin-based Hsp90 inhibitor. It can protect against neuronal cell death.
|
T16719 |
Radicicol
|
12772-57-5
|
98%
|
|
Radicicol is an antifungal antibiotic, impairs mitochondrial replication by targeting P. falciparum topoisomerase VIB. Radicicol is an inhibitor of Hsp90 (IC50: ...
|
T13554 |
Arimoclomol maleate
|
289893-26-1
|
99.98%
|
|
Arimoclomol maleate (BRX-220) (BRX-220) is a heat shock protein (HSP) co-inducer.
|
T6297 |
Alvespimycin hydrochloride
|
467214-21-7
|
99.94%
|
|
Alvespimycin hydrochloride (BMS 826476) is a potent HSP90 inhibitor with IC50 of 62 nM. Phase 2.
|
T3454 |
VER-49009
|
558640-51-0
|
99.93%
|
|
VER-49009 (CCT 129397) is a potent Hsp90 inhibitor(IC50 of 25 nM and Kd of 78 nM).
|
T2908 |
Palmitic acid
|
57-10-3
|
99.87%
|
|
Palmitic acid (Cetylic acid) is a natural product, a common saturated fatty acid found in animals, plants and microorganisms. Palmitic acid has antitumor activit...
|
T28824 |
SNX0723
|
1073969-18-2
|
99.86%
|
|
SNX0723 is a potent Hsp90 Inhibitor with anti-Plasmodium activity. SNX0723 shows high binding affinity for HsHsp90 and PfHsp90 with Kis of 4.4 and 47 nM, respect...
|
T2258 |
VER-50589
|
747413-08-7
|
99.85%
|
|
VER-50589 is a potent HSP90 inhibitor.
|
T6609 |
NMS-E973
|
1253584-84-7
|
99.82%
|
|
NMS-E973 is a potent and selective Hsp90 inhibitor with DC50 of <10 nM for Hsp90 binding, no activiy against a panel of 52 diverse protein kinases.
|
T13553 |
Arimoclomol
|
289893-25-0
|
99.81%
|
|
Arimoclomol (BRX-220 free base) is a co-inducer of heat shock proteins (HSP) and can be used in studies about the treatment of amyotrophic lateral sclerosis (ALS...
|
T9202 |
DDO-5936
|
2355377-13-6
|
99.69%
|
|
DDO-5936 is a potent and specific HSP90-Cdc37 PPI inhibitor.
|
T8858 |
DTHIB
|
897326-30-6
|
99.69%
|
|
DTHIB robustly inhibits the HSF1 cancer gene signature and prostate cancer cell proliferation.
|
T8829 |
2',4'-DIHYDROXYCHALCONE
|
1776-30-3
|
99.59%
|
|
2',4'-DIHYDROXYCHALCONE (2',4'-DHC) as a compound with Hsp90 inhibitory and antifungal effects
|