HCV Protease

NS2-3 protease (of hepatitis C virus, HCV) is an enzyme responsible for proteolytic cleavage between NS2 and NS3, which are non-structural proteins that form part of the HCV virus particle. NS3 protease of hepatitis C virus, on the other hand, is responsible for the cleavage of non-structural protein downstream. Both of these proteases are directly involved in HCV genome replication, that is, during the viral life-cycle that leads to virus multiplication in the host that has been infected by the virus.

Cat. No.	Product name	CAS No.	Purity
T14667	BLT-1	321673-30-7	98.3%
T14667	BLT-1 is a scavenger receptor BI (SR-BI)inhibitor.
T4197	HZ-1157	1009734-33-1	98.23%
T4197	HZ-1157 (DHFR-inhibitor) is a hepatitis C virus (HCV) inhibitor with inhibitory activities toward HCV NS3/4A protease.
T7158	Ombitasvir	1258226-87-7	98.17%
T7158	Ombitasvir (ABT-267) is an orally bioavailable and potent inhibitor of the hepatitis C virus (HCV) non-structural protein 5A (NS5A).with EC50s of 0.82 to 19.3 pM...
T12961	Sofosbuvir impurity F	1337482-17-3	98.05%
T12961	Sofosbuvir impurity F (Sofosbuvir 3',5'-Bis-(S)-phosphate) is both a diastereomer of Sofosbuvir and an impurity of Sofosbuvir which is an inhibitor of HCV RNA re...
T78226	Methyl 2-amino-5-bromobenzoate	52727-57-8	98.05%
T78226	Methyl 2-amino-5-bromobenzoate (Methyl 5-Bromoanthranilate) is a hepatitis C virus NS5b RNA polymerase inhibitor with antimicrobial activity that inhibits Pseudo...
T12962	Sofosbuvir impurity G	1337482-15-1	98.04%
T12962	Sofosbuvir impurity G is a diastereoisomer of Sofosbuvir.Sofosbuvir is an HCV RNA replication inhibitor, with potent anti-hepatitis C virus activity.
T22394	Paritaprevir	1216941-48-8	98.04%
T22394	Paritaprevir (ABT450) is an inhibitor of non-structural protein 3/4A protease with EC50 values of 1 and 0.21 nM for HCV 1a and HCV 1b, respectively.
T15235	Enocitabine	55726-47-1	98.02%
T15235	Enocitabine is a nucleoside analog. Enocitabine inhibits the replication of human cytomegalovirus(HCMV) and it also has antileukemic and antiviral activities. En...
T7215	NM107	20724-73-6	98%
T7215	NM107 (2'-C-Methylcytidine) is a ribonucleoside with broad-spectrum antiviral activity, is an nucleoside inhibitor of the hepatitis C virus (HCV) NS5B polymerase...
T7203	Oglufanide	38101-59-6	98%
T7203	Oglufanide (H-Glu-Trp-OH) is a naturally occurring thymic immunomodulator,and inhibits vascular endothelial growth factor (VEGF).
T5938	4-Phenoxybenzylamine	107622-80-0	98%
T5938	4-Phenoxybenzylamine inhibits the function of the NS3 protein by stabilizing an inactive conformation with an IC50 of about 500 μM against HCV NS3/4a .
T16710	Mericitabine	940908-79-2	97.39%
T16710	Mericitabine (R-7128) is a nucleoside HCV NS5B polymerase inhibitor. It acts as an RNA chain terminator and prevents the elongation of RNA transcripts during rep...
T67787	Adafosbuvir PM	1613589-04-0	97.08%
T67787	Adafosbuvir PM (AL-335 PM) is a small molecule NS5B inhibitor that can be used to study chronic hepatitis C.
T68015	Ruzasvir	1613081-64-3	97.01%
T68015	Ruzasvir (MK-8408) is a novel and potent pan-genotypic inhibitor of hepatitis C virus NS5A with antiviral activity.
T0392	Artemisinin	63968-64-9	97%
T0392	Artemisinin (Qinghaosu) is an ancient Chinese herbal therapy for malarial fevers which has been recently found to have potent activity against many forms of mala...
T6190	Telaprevir	402957-28-2	96.9%
T6190	Telaprevir (Incivek) (VX-950) is an effective inhibitor of HCV NS3-4A serine protease (IC50: 0.35 μM).
T19073	Tris(4-aminophenyl)methane	548-61-8	95.73%
T19073	Tris(4-aminophenyl)methane (Leucopararosaniline), a triphenylmethane dye, is a weak HCV helicase inhibitor.
T50024	7-benzyl-5,6-dimethyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine	56344-53-7	95.00%
T50024	7-benzyl-5,6-dimethyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine is a inhibitor of Hepatitis C Virus(HCV).
T6729	Lomibuvir	1026785-55-6	100%
T6729	Lomibuvir (VCH-222) (VX-222) is a selective, non-nucleoside allosteric inhibitor of HCV NS5B polymerase (RdRp) with a Kd of 17 nM. Lomibuvir inhibits the 1b/Con1...
T16165	Myriocin	35891-70-4	100%
T16165	Myriocin (Thermozymocidin), a metabolite derived from Myriococcum albomyces, is a serine-palmitoyltransferase (SPT) inhibitor with potential antitumour, anticanc...