HCV Protease

NS2-3 protease (of hepatitis C virus, HCV) is an enzyme responsible for proteolytic cleavage between NS2 and NS3, which are non-structural proteins that form part of the HCV virus particle. NS3 protease of hepatitis C virus, on the other hand, is responsible for the cleavage of non-structural protein downstream. Both of these proteases are directly involved in HCV genome replication, that is, during the viral life-cycle that leads to virus multiplication in the host that has been infected by the virus.

Cat. No.	Product name	CAS No.	Purity
T8498	EIDD-1931	3258-02-4	99.14%
T8498	EIDD-1931 (Beta-d-N4-hydroxycytidine) is a ribonucleoside analog with antiviral activity.It inhibits replication of severe acute respiratory syndrome coronavirus...
T3821	Deapioplatycodin D	78763-58-3	99.11%
T3821	Deapioplatycodin D and platycodin D can regulate the production and secretion of airway mucin and, at least in part, explains the traditional use of aqueous extr...
T1643	Penciclovir	39809-25-1	99.1%
T1643	Penciclovir (BRL 39123) is a Herpesvirus Nucleoside Analog DNA Polymerase Inhibitor. In HSV infected cells, penciclovir is phosphorylated by viral thymidine kina...
T2047	AG-1478	153436-53-4	99.03%
T2047	AG-1478 (NSC-693255) (Tyrphostin AG-1478) is a selective EGFR inhibitor.
T27499	GSK-A1	1416334-69-4	98.97%
T27499	GSK-A1 is a specific inhibitor of PI4KA, also inhibited calcium-driven PRL secretion without affecting calcium signaling and Prl expression. GSK-A1 has anti-hepa...
T28762	Setrobuvir	1071517-39-9	98.92%
T28762	Setrobuvir (ANA-598) is an orally active non-nucleoside HCV NS5B polymerase inhibitor with inhibitory effects on de novo RNA synthesis and primer extension with ...
TN2089	Platycodin D3	67884-03-1	98.91%
TN2089	Platycodin D3 is a NF-κB inhibitor, it could as expectorants in diverse inflammatory pulmonary diseases, it can regulate the production and secretion of airway m...
T9580	SB-734117	607368-97-8	98.88%
T9580	SB-734117 inhibits productive replication of several HCMV strains. SB-734117 exhibited polypharmacology and was an inhibitor of several proteins from the AGC and...
T0013	Mecarbinate	15574-49-9	98.87%
T0013	Mecarbinate (Dimecarbin) is arbidol hydrochloride's chemical intermediate.
T22142	RO8191	691868-88-9	98.85%
T22142	RO8191 (CDM-3008) (CDM-3008) is an agonist of interferon (IFN) receptor.
T1822	Clemizole	442-52-4	98.81%
T1822	Clemizole is an H1 histamine receptor antagonist, can inhibit NS4B's RNA binding and hepatitis C virus (HCV) replication.
T11541	HCV-IN-30	1007882-23-6	98.77%
T11541	HCV-IN-30 is an HCV NS5A replication complex inhibitor (IC50s: 901 and 102 nM for genotypes 1a and 1b replicons).
T9717	Chlorcyclizine	82-93-9	98.75%
T9717	CHLORCYCLIZINE is a histamine H1 antagonist and a potent hepatitis C virus (HCV) entry inhibitor.
TQ0090	Nesbuvir	691852-58-1	98.72%
TQ0090	Nesbuvir is a selective hepatitis C virus (HCV) nonstructural protein 5B (NS5B) RNA-dependent polymerase inhibitor.Nesbuvir has an IC50 of 9 nM against hepatocel...
T28830	Sovaprevir	1001667-23-7	98.69%
T28830	Sovaprevir is a non-structural 3 (NS3) protease inhibitor with antiviral activity for the treatment of HCV infection.
T27696	JTK-109	480462-62-2	98.68%
T27696	JTK-109 is an inhibitor of hepatitis C virus NS5B RNA-dependent RNA polymerase inhibitor and inhibits G1b and G3a subgenomic replicons and recombinant enzymes.
T15573	Inarigivir soproxil	942123-43-5	98.44%
T15573	Inarigivir soproxil (SB9200) is an agonist of innate immunity. It also displays effective antiviral activity against resistant hepatitis C virus (HCV) variants (...
T15603	ITX5061	1252679-52-9	98.35%
T15603	ITX5061 is a type II inhibitor of p38 MAPK and scavenger receptor B1 (SRB1) antagonist for the study of hepatitis C virus infection.
T60531	2'-C-Methyladenosine	15397-12-3	98.31%
T60531	2'-C-Methyladenosine is an inhibitor of hepatitis C virus (HCV) replication and a ribonucleoside diphosphate reductase inhibitor from Corynebacterium renalis.2'-...
T26863	BMS-929075	1217338-97-0	98.31%
T26863	BMS-929075 is an orally active HCV NS5B replicase (HCV NS5B replicase) palm site variant inhibitor with potency, high oral bioavailability and pharmacokinetic pa...