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Glucocorticoid Receptor

The glucocorticoid receptor (GR, or GCR) also known as NR3C1 (nuclear receptor subfamily 3, group C, member 1) is the receptor to which cortisol and other glucocorticoids bind. The GR is expressed in almost every cell in the body and regulates genes controlling the development, metabolism, and immune response.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T3316 Fluorometholone 426-13-1 98.21%
Fluorometholone
Fluorometholone (Fluoromethalone) is a corticosteroid, most often used after laser-based refractive surgery. It is marketed under the brand names FML (Allergan) ...
T0294 6α-Methylprednisolone 21-hemisuccinate sodium salt 2375-03-3 98.16%
6α-Methylprednisolone 21-hemisuccinate sodium salt
6α-Methylprednisolone 21-hemisuccinate sodium salt (Asmacortone), a water-soluble ester, is used for allergic, cardiac, and hypoxic emergencies.
T2810 (20S)-Protopanaxatriol 34080-08-5 98.12%
(20S)-Protopanaxatriol
(20S)-Protopanaxatriol (g-PPT)(g-PPT), a metabolite of ginsenoside, could regulate endothelial cell functions through the estrogen receptor and glucocorticoid re...
T15102 Dexamethasone palmitate 14899-36-6 98.08%
Dexamethasone palmitate
Dexamethasone palmitate (DXP), a lipophilic prodrug of Dexamethasone, shows a 47-fold lower affinity for the glucocorticoid receptor than Dexamethasone. Dexameth...
T6580 Meprednisone 1247-42-3 98.07%
Meprednisone
Betapar(Meprednisone (Betapar)) is a glucocorticoid and a methylated derivative of prednisone.
T17217 Vamorolone 13209-41-1 98.04%
Vamorolone
Vamorolone (VBP15) is an orally active dissociative steroidal anti-inflammatory drug and membrane-stabilizer. Vamorolone improves muscular dystrophy without side...
T15000 Cort108297 1018679-79-2 98%
Cort108297
Cort108297 is a selective glucocorticoid receptor modulator and a selective GR antagonist with no affinity for other steroid receptors. Cort108297 showed a high ...
T1749 AL 082D06 256925-03-8 98%
AL 082D06
AL 082D06 (D-06), a selective nonsteroidal glucocorticoid receptor (GR) antagonist (Ki: 210 nM), exhibits outstanding selectivity against AR, ER, MR and PR(Ki > ...
T0947 Dexamethasone acetate 1177-87-3 98%
Dexamethasone acetate
Dexamethasone acetate (NSC 39471) is the acetate salt form of Dexamethasone, a synthetic adrenal corticosteroid with potent anti-inflammatory properties. In addi...
T15389L Glucagon (1-29), bovine, human, porcine hydrochloride 28270-04-4 95.65%
Glucagon (1-29), bovine, human, porcine hydrochloride
Glucagon (1-29), bovine, human, porcine hydrochloride is a peptide hormone, produced by pancreatic α-cells. It activates HNF4α and increases HNF4α phosphorylatio...
T2884 Cortisone 53-06-5 95.48%
Cortisone
Cortisone (17-Hydroxy-11-dehydrocorticosterone) is a corticosteroid with potent glucocorticoid activity.
T6502 Fluocinonide 356-12-7 100%
Fluocinonide
Fluocinonide (Topsyn) (Vanos) is an effective glucocorticoid steroid, utilized in the treatment as the skin disorders anti-inflammatory agent.
T1683 Actriol 547-81-9
Actriol
Actriol (Epiestriol) is always used as Glucocorticoid Receptor agonist.
T6022 LY404039 635318-11-5
LY404039
LY404039 (pomaglumetad) is an effective agonist of recombinant human mGlu2(Ki =149 nM)/mGlu3(Ki =92 nM).
T1573 Flunisolide 3385-03-3
Flunisolide
Flunisolide (Rhinalar) is a synthetic corticosteroid with anti-inflammatory and antiallergic properties.
T1666 Fludrocortisone acetate 514-36-3 98%
Fludrocortisone acetate
Fludrocortisone acetate (9α-Fludrocortisone acetate) , a glucocorticoid-receptor agonist, binds to cytoplasmic receptors, translocates to the nucleus, and subseq...
T1124 Flumethasone 2135-17-3 98%
Flumethasone
Flumethasone (RS-2177) is a glucocorticoid receptor agonist, with anti-inflammatory, antipruritic and vasoconstrictive properties.
T0948L Corticosterone 50-22-6 98%
Corticosterone
Corticosterone (Kendall's compound B) is a sensitive inhibitor of monoamine transport.
T2548 Diflorasone 2557-49-5 98%
Diflorasone
Diflorasone is a synthetic glucocorticoid with anti-inflammatory and immunosuppressive properties. Like other glucocorticoids, diflorasone enters the cell by dif...
T1163 Betamethasone valerate 2152-44-5 98%
Betamethasone valerate
Betamethasone valerate (Luxiq) is a synthetic glucocorticoid with metabolic, immunosuppressive and anti-inflammatory actions.
Fluorometholone
T3316
Fluorometholone (Fluoromethalone) is a corticosteroid, most often used after laser-based refractive surgery. It is marketed under the brand names FML (Allergan) ...
6α-Methylprednisolone 21-hemisuccinate sodium salt
T0294
6α-Methylprednisolone 21-hemisuccinate sodium salt (Asmacortone), a water-soluble ester, is used for allergic, cardiac, and hypoxic emergencies.
(20S)-Protopanaxatriol
T2810
(20S)-Protopanaxatriol (g-PPT)(g-PPT), a metabolite of ginsenoside, could regulate endothelial cell functions through the estrogen receptor and glucocorticoid re...
Dexamethasone palmitate
T15102
Dexamethasone palmitate (DXP), a lipophilic prodrug of Dexamethasone, shows a 47-fold lower affinity for the glucocorticoid receptor than Dexamethasone. Dexameth...
Meprednisone
T6580
Betapar(Meprednisone (Betapar)) is a glucocorticoid and a methylated derivative of prednisone.
Vamorolone
T17217
Vamorolone (VBP15) is an orally active dissociative steroidal anti-inflammatory drug and membrane-stabilizer. Vamorolone improves muscular dystrophy without side...
Cort108297
T15000
Cort108297 is a selective glucocorticoid receptor modulator and a selective GR antagonist with no affinity for other steroid receptors. Cort108297 showed a high ...
AL 082D06
T1749
AL 082D06 (D-06), a selective nonsteroidal glucocorticoid receptor (GR) antagonist (Ki: 210 nM), exhibits outstanding selectivity against AR, ER, MR and PR(Ki > ...
Dexamethasone acetate
T0947
Dexamethasone acetate (NSC 39471) is the acetate salt form of Dexamethasone, a synthetic adrenal corticosteroid with potent anti-inflammatory properties. In addi...
Glucagon (1-29), bovine, human, porcine hydrochloride
T15389L
Glucagon (1-29), bovine, human, porcine hydrochloride is a peptide hormone, produced by pancreatic α-cells. It activates HNF4α and increases HNF4α phosphorylatio...
Cortisone
T2884
Cortisone (17-Hydroxy-11-dehydrocorticosterone) is a corticosteroid with potent glucocorticoid activity.
Fluocinonide
T6502
Fluocinonide (Topsyn) (Vanos) is an effective glucocorticoid steroid, utilized in the treatment as the skin disorders anti-inflammatory agent.
Actriol
T1683
Actriol (Epiestriol) is always used as Glucocorticoid Receptor agonist.
LY404039
T6022
LY404039 (pomaglumetad) is an effective agonist of recombinant human mGlu2(Ki =149 nM)/mGlu3(Ki =92 nM).
Flunisolide
T1573
Flunisolide (Rhinalar) is a synthetic corticosteroid with anti-inflammatory and antiallergic properties.
Fludrocortisone acetate
T1666
Fludrocortisone acetate (9α-Fludrocortisone acetate) , a glucocorticoid-receptor agonist, binds to cytoplasmic receptors, translocates to the nucleus, and subseq...
Flumethasone
T1124
Flumethasone (RS-2177) is a glucocorticoid receptor agonist, with anti-inflammatory, antipruritic and vasoconstrictive properties.
Corticosterone
T0948L
Corticosterone (Kendall's compound B) is a sensitive inhibitor of monoamine transport.
Diflorasone
T2548
Diflorasone is a synthetic glucocorticoid with anti-inflammatory and immunosuppressive properties. Like other glucocorticoids, diflorasone enters the cell by dif...
Betamethasone valerate
T1163
Betamethasone valerate (Luxiq) is a synthetic glucocorticoid with metabolic, immunosuppressive and anti-inflammatory actions.
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