GluR

Glutamate receptors are synaptic and non synaptic receptors located primarily on the membranes of neuronal and glial cells.Glutamate receptors are responsible for the glutamate-mediated postsynaptic excitation of neural cells, and are important for neural communication, memory formation, learning, and regulation.

Cat. No.	Product name	CAS No.	Purity
T26520	ABP688	924298-51-1	97.85%
T26520	ABP688 is a non-competitive and selective mGluR5 antagonist(Ki = 1.7 nM). ABP688 can be used as a PET tracer for clinical imaging.
T21935L	AMN082 free base	83027-13-8	97.76%
T21935L	AMN082 free base is a metabotropic glutamate receptor 7 allosteric agonist.
TP1943L1	Pep2-EVKI acetate(1315378-67-6 free base)	TP1943L1	97.63%
TP1943L1	Pep2-EVKI acetate is a cell-permeable peptide. Pep2-EVKI acetate interferes the interaction between protein interacting with C-kinase (PICK1) and GluR2 AMPA rece...
T14389	AZD 9272	327056-26-8	97.53%
T14389	AZD 9272 is a brain-permeable mGluR5 antagonist for the study of gastroesophageal reflux.
T19698	CX614	191744-13-5	97.43%
T19698	CX614 is a positive allosteric modulator of the AMPA receptor with respect to AMPA.
T35028	Valiglurax	1976050-09-5	97.38%
T35028	Valiglurax (VU2957), also known as VU0652957 and VU2957, is a potent, selective, CNS penetrant, and orally bioavailable mGlu4 PAM. VU2957 possessed attractive in...
T29118	VU 0469650	1443748-47-7	97.27%
T29118	VU 0469650 is a potent and selective negative allosteric modulator of mGluR1 (IC50 = 99 nM).
T3482	CFMTI	864864-17-5	97.23%
T3482	CFMTI is a potent and selective metabotropic glutamate receptor (mGluR) 1 allosteric antagonist (IC50: 2.6 nM). The selectivity of CFMTI to mGluR1 is higher 2000...
T23010	MNI 137	946619-21-2	97.21%
T23010	MNI 137 is a negative allosteric modulator of mGlu2. MNI 137 inhibits glutamate-induced calcium mobilization with IC50s of 8.3 and 12.6 nM for human and rat.
TP1944L1	Pep2-SVKI acetate	TP1944L1	97.14%
TP1944L1	Pep2-SVKI acetate(pep2-SVKI acetate (328944-75-8 free base)) is a synthetic peptide salt that prevents internalization of AMPA-type glutamate receptor.
T21747	VU0483605	1623101-11-0	97.03%
T21747	VU0483605 is an effective and selective positive allosteric modulator of mGluR1 with EC50s of 390 and 356 nM for human and rat, respectively.
T27748L	KRP-199 sodium		96.85%
T27748L	KRP-199 sodium sodium is highly potent and selective for AMPA-R in vitro and exhibits good neuroprotection in vivo.
T16977	Talampanel	161832-65-1	95.54%
T16977	Talampanel (LY-300164) is an orally and selective α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptor antagonist with anti-seizure activity. Talampanel (IV...
T29135	VU0422288	1630936-95-6	95.48%
T29135	VU0422288 (ML396) is a potent orthosteric modulator of type III mGlu receptors (mGlus).VU0422288 shows inhibition of mGluR4, mGluR7, and mGluR8 in a calcium mobi...
T22730	DL-AP3	20263-06-3	95%
T22730	DL-AP3 is a competitive group I metabotropic glutamate receptor antagonist and inhibitor of phosphoserine phosphatase.
T3483	FTIDC	873551-53-2	94.58%
T3483	FTIDC is a highly potent and selective allosteric antagonist of mGluR1 receptors and shows very weak potency against human and rat mGluR5 receptors. The inhibiti...
T2194	Direct Blue 1	2610-05-1	50%
T2194	Direct Blue 1 (Pontamine sky blue), a counterstain for background autofluorescence in immunofluorescence histochemistry, structurally resembles glutamate and ope...
T15812	LY2979165	1311385-32-6	100.00%
T15812	LY2979165 (mGlu2 agonist) is an orthosteric agonist of mGluR2 and can be used in studies about serving as an anti-depressant.
T3565	VU0155041	1093757-42-6	100%
T3565	VU0155041 is an effective and positive allosteric modulator/allosteric agonist at mGlu4 receptors (EC50: 798/693 nM, at human/rat).
T7823	IDRA-21	22503-72-6	100%
T7823	IDRA-21 is a positive AMPA receptor modulator.