T82821 |
BRD9 Degrader-1
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98%
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BRD9 Degrader-1 functions as a BRD9 degrader, demonstrating micromolar binding affinity towards BRD9 and nanomolar affinity for the ternary complex involving BRD...
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T10520 |
BET-IN-2
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2104688-91-5
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98%
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BET-IN-2 is a BET inhibitor (IC50: 52 nM for BRD4-BD1).
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T13849 |
PROTAC BET Degrader-1
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2093386-22-0
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98%
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PROTAC BET Degrader-1 is a potent degrader of BET based on PROTAC.
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T14512 |
BAZ2-ICR
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1665195-94-7
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98%
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BAZ2-ICR is an epigenetic chemical probe and it also is a potent, selective, cell active and orally active BAZ2A/B bromodomains inhibitor with IC50s of 130 nM an...
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T11597 |
IACS-9571
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1800477-30-8
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98%
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IACS-9571 is a selective and potent inhibitor of TRIM24 and BRPF1, (IC50: 8 nM for TRIM24; Kds: 31 nM and 14 nM for TRIM24 and BRPF1).
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T15443 |
GSK8814
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1997369-78-4
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98%
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GSK8814 is a selective and ATAD2/2B bromodomain chemical probe and inhibitor (binding constant pKd=8.1 and a pKi=8.9 in BROMOscan). GSK8814 displays 500-fold sel...
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T15397 |
GNE-049
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1936421-41-8
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98%
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GNE-049 is a highly potent and selective inhibitor of CBP (IC50: 1.1 nM in TR-FRET assay). GNE-049 also inhibits BRET and BRD4(1) (IC50s: 12 nM and 4200 nM, resp...
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T17294 |
ZL0454
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2229042-77-5
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98%
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ZL0454 is an effective and selective Bromodomain-containing protein 4 inhibitors (IC50: 49 and 32 nM for BD1 and BD2).
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T13835 |
PROTAC BRD4 Degrader-3
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2313234-00-1
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98%
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PROTAC BRD4 Degrader-3 is an efficacious degrader of PROTAC BRD4.
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T13785 |
MZP-54
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2010159-47-2
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98%
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MZP-54 is a selective degrader of BRD3/4 based on PROTAC technology(Kd of 4 nM for Brd4BD2)
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T12560 |
PROTAC BRD9 Degrader-1
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2097971-01-0
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98%
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PROTAC BRD9 Degrader-1 is a lead PROTAC BRD9 chemical degrader with IC50 of 13.5 nM.
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T11291 |
FKBP12 PROTAC dTAG-13
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2064175-41-1
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98%
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FKBP12 PROTAC dTAG-13 (dTAG-13) is a degrader of FKBP12F36V with expression of FKBP12F36V in-frame with a protein of interest. FKBP12 PROTAC dTAG-13 (dTAG-13) al...
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T13850 |
PROTAC BET degrader-3
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T13850
|
98%
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PROTAC BET Degrader-3 is a potent degrader OF BET based on PROTAC.
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T15399 |
GNE-207
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2158266-58-9
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98%
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GNE-207 is a selective and orally bioavailable inhibitor of the bromodomain of CBP (IC50: 1 nM). It has a selective index of >2500-fold against BRD4 (1). GNE-207...
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T17297 |
ZXH-3-26
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2243076-67-5
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98%
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ZXH-3-26 is a selective degrader of the PROTAC BRD4 (DC50/5h: ~ 5 nM).
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T13977 |
(R)-UT-155
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2031161-54-1
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98%
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(R)-UT-155 is a selective androgen receptor degrader (SARD) ligand.
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T72096 |
Eleven-Nineteen-Leukemia Protein IN-1
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2894121-68-5
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98%
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Eleven-Nineteen-Leukemia Protein IN-1 is a potent inhibitor of the ENL YEATS domain, exhibiting an IC50 of 14.5 nM. It binds to the ENL protein, consequently inc...
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T72097 |
Eleven-Nineteen-Leukemia Protein IN-2
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2894121-78-7
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98%
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Eleven-Nineteen-Leukemia Protein IN-2 (compound 23), an ENL inhibitor, exhibits an IC50 of 10.7 nM and is utilized for leukemia research [1].
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T72098 |
Eleven-Nineteen-Leukemia Protein IN-3
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2894121-83-4
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98%
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Eleven-Nineteen-Leukemia Protein IN-3, an orally active ENL YEATS domain inhibitor, exhibits potent activity with an IC50 of 15.4 nM. It downregulates MYC expres...
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T72722 |
Physachenolide C
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791117-61-8
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98%
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Physachenolide C, a selective BET inhibitor, induces apoptosis and arrests the cell cycle at the G0-G1 phase, exhibiting antitumor activity [1].
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