T11986 |
Mebeverine acid
|
475203-77-1
|
99.66%
|
|
Mebeverine acid (Mebeverine metabolite Mebeverine acid) is a secondary metabolite of Mebeverine and can be used as a marker of oral exposure to Mebeverine.
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T35688 |
MTIC
|
3413-72-7
|
99.51%
|
|
MTIC is the active metabolite of Temozolomide (TMZ) with anticancer and antitumor activity and is used in the study of melanoma.3'-Sialyllactose (3'-SL) sodium i...
|
T5539 |
GS-443902
|
1355149-45-9
|
|
|
GS-441524 was shown to be a safe and effective treatment for feline infectious peritonitis (FIP). The optimum dosage was found to be 4.0 mg/kg SC q24h for at lea...
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T78069 |
RPR132595A hydrochloride
|
|
98%
|
|
RPR132595A (NPC) hydrochloride, an active metabolite of CPT-11, is produced via cytochrome P-450 3A4 (CYP3A4) metabolism and is ultimately eliminated via urinary...
|
T78130 |
N-Methyl Palbociclib
|
571189-51-0
|
98%
|
|
N-Methyl Palbociclib is an impurity of the orally active selective CDK4 and CDK6 inhibitor Palbociclib (PD 0332991).
|
T78136 |
Perindopril acyl-β-D-glucuronide
|
120398-66-5
|
98%
|
|
Perindopril acyl-β-D-glucuronide is a metabolite of the ACE inhibitor perindopril [1].
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T78547 |
2-Phenyl-2-(2-pyridyl)acetonitrile
|
5005-36-7
|
98%
|
|
2-Phenyl-2-(2-pyridyl)acetonitrile represents the principal metabolite of the antigastric agent SC 15396, produced by the supernatant fraction of rat liver homog...
|
T78589 |
3-Hydroxycarbofuran
|
16655-82-6
|
98%
|
|
3-Hydroxycarbofuran, a principal metabolite of Carbofuran, acts as a reversible inhibitor of acetylcholinesterase (AChE) [1].
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T78595 |
3-Hydroxyphenazepam
|
70030-11-4
|
98%
|
|
3-Hydroxyphenazepam, an active metabolite of Cinazepam, acts as a GABAA receptor agonist. This compound has the ability to inhibit synaptosomal transporter-media...
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T80022 |
(R)-tert-OMe-byakangelicin
|
89560-97-4
|
98%
|
|
(R)-tert-OMe-byakangelicin, a furanocoumarin, exhibits inhibitory effects on liver drug metabolizing enzyme (DME) activity and can be isolated from the immature ...
|
T80635 |
Gentisuric acid
|
25351-24-0
|
98%
|
|
Gentisuric acid, an Aspirin metabolite and a substrate of α-amidating monooxygenase (PAM), mitigates DNA damage induced by Mitomycin C. [1] [2]
|
T80658 |
Quercetin 7-glucuronide
|
38934-20-2
|
98%
|
|
Quercetin 7-glucuronide (Quercetin 7-O-β-glucuronide), a Quercetin metabolite found in Madagascarian Uncarina species, has the capability to inhibit LDL oxidatio...
|
T82599 |
DDC 3′-O-β-D glucuronide
|
|
98%
|
|
Compound 5, DDC 3′-O-β-D-glucuronide, is a drug metabolite with properties that inhibit the fibrillization and oligomerization of Aβ42, suggesting its potential ...
|
T36896 |
6α-hydroxy Paclitaxel
|
153212-75-0
|
98%
|
|
6α-hydroxy Paclitaxel (6α-OH-PTX) is a major metabolite of the anticancer compound paclitaxel and is partially cytotoxic.
|
T0617 |
Nicotinamide N-oxide
|
1986-81-8
|
99.9%
|
|
Nicotinamide N-oxide (Nicotinamide 1-oxide) is recognized as an in vivo metabolite of nicotinamide which is a precurser of nicotinamide-adenine dinucleotide (NAD...
|
T8183 |
Deslanoside
|
17598-65-1
|
99.89%
|
|
Deslanoside (Desacetyllanatoside C) is a rapidly acting cardiac glycoside used to treat congestive heart failure and supraventricular arrhythmias due to reentry ...
|
T2149 |
Vinburnine
|
4880-88-0
|
99.86%
|
|
Vinburnine (Eburnalritardo) is a vasodilator. Vinburnine is a vinca alkaloid and a metabolite of vincamine.
|
T67905 |
GS-829845
|
1257705-09-1
|
99.78%
|
|
GS-829845 is a JAK1 inhibitor, the main component of the active metabolite of Filgotinib, which is approximately 10-fold less potent and has a longer half-life t...
|
T20723 |
LGE-899
|
1221722-10-6
|
99.77%
|
|
LGE-899 (Sonidegib metabolite M48) is a main metabolite of Sonidegib which is an inhibitor of the hedgehog pathway. The Tmax of LGE-899(60 h) is much longer than...
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TN1742 |
Homovanillyl alcohol
|
2380-78-1
|
99.74%
|
|
Homovanillyl alcohol is a biological metabolite of Hydroxytyrosol. Hydroxytyrosol is a phenolic compound that is present in virgin olive oil (VOO) and wine. Homo...
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