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Dopamine Receptor

Dopamine receptors are a class of G protein-coupled receptors that are prominent in the vertebrate central nervous system (CNS). Dopamine receptors activate different effectors through not only G-protein coupling, but also signaling through different protein (dopamine receptor-interacting proteins) interactions.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T3497 Ocaperidone 129029-23-8 99.94%
Ocaperidone
Ocaperidona (Ocaperidone (Ocaperidona)), a very high affinity dopamine D2 antagonist.
T16392 ONC206 1638178-87-6 99.93%
ONC206
ONC206, an analogue of the TRAIL inducer ONC201, acts as a selective antagonist of the D2-like dopamine receptors (DRD2/3/4) at nanomolar concentrations and poss...
T0455 Clozapine 5786-21-0 99.93%
Clozapine
Clozapine (HF 1854) is a tricylic dibenzodiazepine, classified as an atypical antipsychotic agent. It binds several types of central nervous system receptors, an...
T1567 Olanzapine 132539-06-1 99.92%
Olanzapine
Olanzapine (LY170053) is an atypical antipsychotic that is used currently in the treatment of schizophrenia and bipolar illness.
T1412 Loxapine succinate 27833-64-3 99.92%
Loxapine succinate
Loxapine succinate (Loxapac), a D2DR and D4DR inhibitor, is utilized in schizophrenia.
T5397 A-381393 726174-00-1 99.92%
A-381393
A-381393 is a selective and brain penetrate dopamine D4 receptor antagonist (Kis: 1.9/1.5/1.6 nM for human dopamine D4.2/D4.4/D4.7 receptor).
T14853 Cabergoline 81409-90-7 99.92%
Cabergoline
Cabergoline (FCE-21336) is an ergot derived-dopamine D2-like receptor agonist. It has high affinity for D2, D3, and 5-HT2B receptors (Ki=0.7, 1.5, and 1.2, respe...
T1540 Doxepin hydrochloride 1229-29-4 99.91%
Doxepin hydrochloride
Doxepin hydrochloride (Aponal) is a dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation....
T3278 Piribedil 3605-01-4 99.91%
Piribedil
Piribedil (Trivastan) is a dopamine D2 agonist, used in the treatment of Parkinson's disease.
T2793 Tetrahydropalmatine 2934-97-6 99.91%
Tetrahydropalmatine
Tetrahydropalmatine (DL-Tetrahydropalmatine) is an active component isolated from corydalis, suppressing amygdaloid release of dopamine to inhibit an epileptic a...
T3085 Piperacetazine 3819-00-9 99.9%
Piperacetazine
Piperacetazine (Piperacetazinum), an antipsychotic prodrug, is used forschizophrenia.
T2874 Tetrahydroberberine 522-97-4 99.89%
Tetrahydroberberine
Tetrahydroberberine (Canadine) is an isoquinoline alkaloid isolated from corydalis tuber, has a micromolar affinity for dopamine D(2) receptors.
T4S0779 D-tetrahydropalmatine 3520-14-7 99.89%
D-tetrahydropalmatine
D-Tetrahydropalmatine is a organic cation transporter 1 (OCT1) inhibitor, it can obviously inhibit the uptake of monocrotaline (MCT) in MDCK-hOCT1 cells and isol...
T5842 Bromocriptine mesylate 22260-51-1 99.87%
Bromocriptine mesylate
Bromocriptine mesylate (CB-154) is a potent dopamine receptor agonist that binds the D2 receptor with highest affinity (Ki = 2.5 nM)
T9100 BP 897 192384-87-5 99.87%
BP 897
BP 897 (2-Naphthalenecarboxamide, N-[4-[4-(2-methoxyphenyl)-1-piperazinyl]butyl]-) is a potent and selective dopamine D3 receptor agonist, and a weak dopamine D2...
T0287 Hexamethonium Bromide 55-97-0 99.87%
Hexamethonium Bromide
Hexamethonium Bromide (Hexamethonium Dibromide), a specific antagonist of neuronal-type nicotinic AChR in ganglia, is poorly absorbed from the gastrointestinal t...
T0505 Methyldopa 555-30-6 99.86%
Methyldopa
Methyldopa (MK-351), an alpha-adrenergic agonist (selective for α2-adrenergic receptors) psychoactive medicine, is served as an antihypertensive or sympatholytic...
T1406 Amantadine hydrochloride 665-66-7 99.86%
Amantadine hydrochloride
Amantadine hydrochloride (CI-719) is an antiviral that is used in the prophylactic or symptomatic treatment of influenza A and Parkinson disease.
T0469 Octopamine hydrochloride 770-05-8 99.85%
Octopamine hydrochloride
Octopamine hydrochloride ((±)-p-Octopamine hydrochlorid) is a biogenic monoamine structurally associated with noradrenaline. It can serve as a neurohormone, a ne...
T2917 Tetrahydropalmatine hydrochloride 6024-85-7 99.84%
Tetrahydropalmatine hydrochloride
Tetrahydropalmatine hydrochloride (Gindarine hydrochloride) is an isoquinoline alkaloid found in several different plant species, mainly in the Corydalis genus (...
Ocaperidone
T3497
Ocaperidona (Ocaperidone (Ocaperidona)), a very high affinity dopamine D2 antagonist.
ONC206
T16392
ONC206, an analogue of the TRAIL inducer ONC201, acts as a selective antagonist of the D2-like dopamine receptors (DRD2/3/4) at nanomolar concentrations and poss...
Clozapine
T0455
Clozapine (HF 1854) is a tricylic dibenzodiazepine, classified as an atypical antipsychotic agent. It binds several types of central nervous system receptors, an...
Olanzapine
T1567
Olanzapine (LY170053) is an atypical antipsychotic that is used currently in the treatment of schizophrenia and bipolar illness.
Loxapine succinate
T1412
Loxapine succinate (Loxapac), a D2DR and D4DR inhibitor, is utilized in schizophrenia.
A-381393
T5397
A-381393 is a selective and brain penetrate dopamine D4 receptor antagonist (Kis: 1.9/1.5/1.6 nM for human dopamine D4.2/D4.4/D4.7 receptor).
Cabergoline
T14853
Cabergoline (FCE-21336) is an ergot derived-dopamine D2-like receptor agonist. It has high affinity for D2, D3, and 5-HT2B receptors (Ki=0.7, 1.5, and 1.2, respe...
Doxepin hydrochloride
T1540
Doxepin hydrochloride (Aponal) is a dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation....
Piribedil
T3278
Piribedil (Trivastan) is a dopamine D2 agonist, used in the treatment of Parkinson's disease.
Tetrahydropalmatine
T2793
Tetrahydropalmatine (DL-Tetrahydropalmatine) is an active component isolated from corydalis, suppressing amygdaloid release of dopamine to inhibit an epileptic a...
Piperacetazine
T3085
Piperacetazine (Piperacetazinum), an antipsychotic prodrug, is used forschizophrenia.
Tetrahydroberberine
T2874
Tetrahydroberberine (Canadine) is an isoquinoline alkaloid isolated from corydalis tuber, has a micromolar affinity for dopamine D(2) receptors.
D-tetrahydropalmatine
T4S0779
D-Tetrahydropalmatine is a organic cation transporter 1 (OCT1) inhibitor, it can obviously inhibit the uptake of monocrotaline (MCT) in MDCK-hOCT1 cells and isol...
Bromocriptine mesylate
T5842
Bromocriptine mesylate (CB-154) is a potent dopamine receptor agonist that binds the D2 receptor with highest affinity (Ki = 2.5 nM)
BP 897
T9100
BP 897 (2-Naphthalenecarboxamide, N-[4-[4-(2-methoxyphenyl)-1-piperazinyl]butyl]-) is a potent and selective dopamine D3 receptor agonist, and a weak dopamine D2...
Hexamethonium Bromide
T0287
Hexamethonium Bromide (Hexamethonium Dibromide), a specific antagonist of neuronal-type nicotinic AChR in ganglia, is poorly absorbed from the gastrointestinal t...
Methyldopa
T0505
Methyldopa (MK-351), an alpha-adrenergic agonist (selective for α2-adrenergic receptors) psychoactive medicine, is served as an antihypertensive or sympatholytic...
Amantadine hydrochloride
T1406
Amantadine hydrochloride (CI-719) is an antiviral that is used in the prophylactic or symptomatic treatment of influenza A and Parkinson disease.
Octopamine hydrochloride
T0469
Octopamine hydrochloride ((±)-p-Octopamine hydrochlorid) is a biogenic monoamine structurally associated with noradrenaline. It can serve as a neurohormone, a ne...
Tetrahydropalmatine hydrochloride
T2917
Tetrahydropalmatine hydrochloride (Gindarine hydrochloride) is an isoquinoline alkaloid found in several different plant species, mainly in the Corydalis genus (...
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TargetMol