COX

Cyclooxygenase (COX), officially known as prostaglandin-endoperoxide synthase (PTGS), is an enzyme (specifically, a family of isozymes) that is responsible for formation of prostanoids, including thromboxane and prostaglandins such as prostacyclin, from arachidonic acid. A member of the animal-type heme peroxidase family, it is also known as prostaglandin G/H synthase.

Cat. No.	Product name	CAS No.	Purity
T15645	Pamicogrel	101001-34-7	98.96%
T15645	Pamicogrel (KBT3022) is an inhibitor of COX.
T12784	RWJ 63556	190967-35-2	98.91%
T12784	RWJ 63556 is an orally active inhibitor of COX-2 selective/5-lipoxygenase, shows anti-inflammatory activities.
T1258	Nabumetone	42924-53-8	98.91%
T1258	Nabumetone (BRL14777)(BRL14777) is a non-steroidal anti-inflammatory drug and its active metabolite 6MNA inhibits the enzymes cyclo-oxygenase I and II.
T2569	Chlorotrianisene	569-57-3	98.88%
T2569	Chlorotrianisene (tri-p-anisylchloroethylene) is an orally bioavailable, highly lipophilic, synthetic triphenylethylene (TPE) derivative and selective estrogen r...
T10032	COX-2-IN-2	134729-13-8	98.85%
T10032	COX-2-IN-2, a selective inducible COX2 inhibitor, exhibits potent inhibition with an IC50 of 0.24 μM. Meanwhile, COX-2-IN-1 functions as an anti-inflammatory age...
TN1041	Quercimeritrin	491-50-9	98.84%
TN1041	Quercimeritrin (Quercetin-7-O-beta-D-glucopyranoside) has antibacterial activity, it shows promising activity against Staphylococcus aureus.
T6S0722	Isoorientin	4261-42-1	98.84%
T6S0722	Isoorientin (Homoorientin) has antioxidant activity.
T6S0413	Pectolinarigenin	520-12-7	98.77%
T6S0413	1. Pectolinarigenin (Pectolinaringenin) exhibits hepatoprotective activity mainly via SOD antioxidant mechanism. 2. Pectolinarigenin possesses anti-inflammatory ...
T0907	Sulfasalazine	599-79-1	98.73%
T0907	Sulfasalazine (Azulfidine) is a synthetic salicylic acid derivative with affinity for connective tissues containing elastin and formulated as a prodrug
T4092	AG126	118409-62-4	98.72%
T4092	AG126 (Tyrphostin AG126) selectively inhibits the phosphorylation of ERK1 (p44) and ERK2 (p42) at 25-50 μM. It blocks the production of TNF-α in vitro2 and in vi...
T16817	S-2474	158089-95-3	98.72%
T16817	S-2474, an inhibitor of COX-2 and 5-lipoxygenase, has anti-inflammatory and neuroprotective activities and inhibits Abeta (25 - 35) and Abeta (1 - 40) induced ce...
T68136	(Iso)-Samixogrel	133276-52-5	98.67%
T68136	(Iso)-Samixogrel shows activity against Carbonic anhydrase and Cyclooxygenase 2.
T6677	Sophocarpine	6483-15-4	98.67%
T6677	Sophocarpine, a major ingredient of Sophora alopecuroides, has a wide range of pharmacological effects.
TN1579	Dihydrocucurbitacin B	13201-14-4	98.67%
TN1579	Dihydrocucurbitacin B (23,24-dihydrocucurbitacin B) is isolated from the roots of Cayaponia tayuya with anti-cancer activity.
TN1291	7,3',4'-Tri-O-methylluteolin	29080-58-8	98.66%
TN1291	7,3',4'-Tri-O-methylluteolin (5-Hydroxy-3',4',7-trimethoxyflavone) has anti-inflammatory, antibacterial and antifungal activities, it also shows moderate antitry...
T1191	Metamizole sodium hydrate	5907-38-0	98.64%
T1191	Metamizole sodium hydrate (Analgin) is a potent analgesic drug that has been demonstrated to inhibit cyclooxygenase (COX). Target: COX Dipyrone is a potent analg...
T5431	[10]-Shogaol	36752-54-2	98.62%
T5431	[10]-Shogaol (10-Shogaol) is an extract from ginger displaying antioxidant activity. It also may contain hypolipidemic and insulin-sensitizing effects.
T0050	Ampyrone	83-07-8	98.57%
T0050	Ampyrone (4-Aminoantipyrine) is a reagent for glucose determination in the presence of peroxidase and phenol.
T7081	CCCP	555-60-2	98.55%
T7081	CCCP (Carbonyl Cyanide m-Chlorophenylhydrazone) is an oxidative phosphorylation (OXPHOS) inhibitor and mitochondrial proton carrier uncoupler. CCCP inhibits the ...
T3884	Neoandrographolide	27215-14-1	98.52%
T3884	Neoandrographolide (Neoandrographiside) has potent hypolipidemic effect and protects the cardiovascular without significant liver damage.Neoandrographolide has a...