Home Tools
Log in
Cart

COX

Cyclooxygenase (COX), officially known as prostaglandin-endoperoxide synthase (PTGS), is an enzyme (specifically, a family of isozymes) that is responsible for formation of prostanoids, including thromboxane and prostaglandins such as prostacyclin, from arachidonic acid. A member of the animal-type heme peroxidase family, it is also known as prostaglandin G/H synthase.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T6387 Ampiroxicam 99464-64-9 99.15%
Ampiroxicam
Ampiroxicam (Flucam) is a nonselective cyclooxygenase inhibitor uesd as anti-inflammatory drug.
T0399 Methyl salicylate 119-36-8 99.13%
Methyl salicylate
Methyl salicylate (Gaultheria oil) is an organic ester naturally produced by many species of plants, particularly wintergreens. For acute joint and muscular pain...
T7838 Losartan Carboxaldehyde 114798-36-6 99.12%
Losartan Carboxaldehyde
Losartan Carboxaldehyde is an endothelial cyclooxygenase (COX)-2 inhibitor.
T2S2335 Dehydroevodiamine 67909-49-3 99.12%
Dehydroevodiamine
Dehydroevodiamine (DHED), a constituent of Evodia rutaecarpa, has various biological effects such as hypotensive, negative chronotropic, ion channel depressant, ...
TN1100 Nepodin 3785-24-8 99.12%
Nepodin
Nepodin has antimalarial, and anti-inflammatory activities, it shows significant cyclooxygenase (COX) inhibitory activity. Nepodin has an antidiabetic effect, wh...
T0285 Isoxicam 34552-84-6 99.12%
Isoxicam
Isoxicam (Isoxicamum) is a non-steroidal anti-inflammatory drug that is not marketed in the United States.
T22368 Metyrosine 672-87-7 99.11%
Metyrosine
Metyrosine (α-Methyltyrosine) is an antihypertensive drug and could be used as a tyrosine hydroxylase inhibitor.Metyrosine significantly inhibits high COX-2 acti...
T68093 Lobuprofen 98207-12-6 99.09%
Lobuprofen
Lobuprofen is a small molecule COX inhibitor that is used to treat neurological disorders.
T32824 LM-1685 416901-58-1 99.09%
LM-1685
LM-1685 is a potent and selective inhibitor of COX-2 IN human monocytes and whole blood with IC50 of 0.65µM and IC50 = 4.3μM, respectively, and is a potential co...
T0260 Meclofenamic acid sodium 6385-02-0 99.08%
Meclofenamic acid sodium
Meclofenamic acid sodium (Movens), a non-steroidal anti-inflammatory agent, has properties of antipyretic and antigranulation activities. It also inhibits prosta...
T0822 Catechin 154-23-4 99.05%
Catechin
Catechin (Cianidanol) is a flavan-3-ol, a type of natural phenol and antioxidant.
T0443 Salicin 138-52-3 99.04%
Salicin
Salicin (Salicine), a phenol β-glycoside produced from willow bark, shows anti-inflammatory functions.
T1401 Meclofenoxate hydrochloride 3685-84-5 99.04%
Meclofenoxate hydrochloride
Meclofenoxate hydrochloride (Lucidril) is an ester of DIMETHYLAMINOETHANOL and para-chlorophenoxyacetic acid. It has been shown to improve memory and general cog...
T7662 α-Demethylnaproxen 23981-47-7 99.03%
α-Demethylnaproxen
α-Demethylnaproxen is a competitive inhibitor of COX(Ki values of 21 and 19 μM for ovine COX-1 and -2, respectively)
T2778 (+)-Catechin Hydrate 225937-10-0 99.03%
(+)-Catechin Hydrate
(+)-Catechin Hydrate is an antioxidant flavonoid of plant origin; a free radical scavenger, preventing free radical-mediated damage in a variety of biological sy...
T7724 Tepoxalin 103475-41-8 99.03%
Tepoxalin
Tepoxalin (RWJ 20485) is a 5-lipoxygenase inhibitor potentially for the treatment of asthma, osteoarthritis. Tepoxalin inhibits COX-1, COX-2, and 5-LOX. Tepoxali...
T0708 Oxaprozin 21256-18-8 99.02%
Oxaprozin
Oxaprozin (Oxaprozinum) is a Nonsteroidal Anti-inflammatory Drug. The mechanism of action of oxaprozin is as a Cyclooxygenase Inhibitor. The chemical classificat...
T3402 20(S)-Ginsenoside Rg3 14197-60-5 98.99%
20(S)-Ginsenoside Rg3
20(S)-Ginsenoside Rg3 (Rg3) possess an ability to inhibit the lung metastasis of tumor cells via inhibition of the adhesion and invasion of tumor cells. It inhib...
T10355 Apyramide 68483-33-0 98.99%
Apyramide
Apyramide is an anti-inflammatory agent (NSAID) and behaves as a prodrug of indomethacin. Indomethacin is a potent, blood-brain permeable and nonselective inhibi...
T3868 Agnuside 11027-63-7 98.98%
Agnuside
Agnuside (chasteberry oil) inhibits COX-2 (IC50: 0.026 mg/ml) but exhibits less than 10% inhibition of COX-1 at this concentration. It also inhibits 46.3, 66.8, ...
Ampiroxicam
T6387
Ampiroxicam (Flucam) is a nonselective cyclooxygenase inhibitor uesd as anti-inflammatory drug.
Methyl salicylate
T0399
Methyl salicylate (Gaultheria oil) is an organic ester naturally produced by many species of plants, particularly wintergreens. For acute joint and muscular pain...
Losartan Carboxaldehyde
T7838
Losartan Carboxaldehyde is an endothelial cyclooxygenase (COX)-2 inhibitor.
Dehydroevodiamine
T2S2335
Dehydroevodiamine (DHED), a constituent of Evodia rutaecarpa, has various biological effects such as hypotensive, negative chronotropic, ion channel depressant, ...
Nepodin
TN1100
Nepodin has antimalarial, and anti-inflammatory activities, it shows significant cyclooxygenase (COX) inhibitory activity. Nepodin has an antidiabetic effect, wh...
Isoxicam
T0285
Isoxicam (Isoxicamum) is a non-steroidal anti-inflammatory drug that is not marketed in the United States.
Metyrosine
T22368
Metyrosine (α-Methyltyrosine) is an antihypertensive drug and could be used as a tyrosine hydroxylase inhibitor.Metyrosine significantly inhibits high COX-2 acti...
Lobuprofen
T68093
Lobuprofen is a small molecule COX inhibitor that is used to treat neurological disorders.
LM-1685
T32824
LM-1685 is a potent and selective inhibitor of COX-2 IN human monocytes and whole blood with IC50 of 0.65µM and IC50 = 4.3μM, respectively, and is a potential co...
Meclofenamic acid sodium
T0260
Meclofenamic acid sodium (Movens), a non-steroidal anti-inflammatory agent, has properties of antipyretic and antigranulation activities. It also inhibits prosta...
Catechin
T0822
Catechin (Cianidanol) is a flavan-3-ol, a type of natural phenol and antioxidant.
Salicin
T0443
Salicin (Salicine), a phenol β-glycoside produced from willow bark, shows anti-inflammatory functions.
Meclofenoxate hydrochloride
T1401
Meclofenoxate hydrochloride (Lucidril) is an ester of DIMETHYLAMINOETHANOL and para-chlorophenoxyacetic acid. It has been shown to improve memory and general cog...
α-Demethylnaproxen
T7662
α-Demethylnaproxen is a competitive inhibitor of COX(Ki values of 21 and 19 μM for ovine COX-1 and -2, respectively)
(+)-Catechin Hydrate
T2778
(+)-Catechin Hydrate is an antioxidant flavonoid of plant origin; a free radical scavenger, preventing free radical-mediated damage in a variety of biological sy...
Tepoxalin
T7724
Tepoxalin (RWJ 20485) is a 5-lipoxygenase inhibitor potentially for the treatment of asthma, osteoarthritis. Tepoxalin inhibits COX-1, COX-2, and 5-LOX. Tepoxali...
Oxaprozin
T0708
Oxaprozin (Oxaprozinum) is a Nonsteroidal Anti-inflammatory Drug. The mechanism of action of oxaprozin is as a Cyclooxygenase Inhibitor. The chemical classificat...
20(S)-Ginsenoside Rg3
T3402
20(S)-Ginsenoside Rg3 (Rg3) possess an ability to inhibit the lung metastasis of tumor cells via inhibition of the adhesion and invasion of tumor cells. It inhib...
Apyramide
T10355
Apyramide is an anti-inflammatory agent (NSAID) and behaves as a prodrug of indomethacin. Indomethacin is a potent, blood-brain permeable and nonselective inhibi...
Agnuside
T3868
Agnuside (chasteberry oil) inhibits COX-2 (IC50: 0.026 mg/ml) but exhibits less than 10% inhibition of COX-1 at this concentration. It also inhibits 46.3, 66.8, ...
1 ... 11 12 13 ... 20
TargetMol