T4085 |
Paris saponin VII
|
68124-04-9
|
99.63%
|
|
Paris saponin VII (Dioscini) shows inhibitory effects on cell proliferation.
|
T3867 |
Alpinetin
|
36052-37-6
|
99.61%
|
|
Alpinetin ((-)-alpinetin) has antibacterial activity.Alpinetin has anti-inflammatory activity.Alpinetin can enhance the sensitivity of HepG2 hepatoma cells to th...
|
T5210 |
BAI1
|
335165-68-9
|
99.58%
|
|
BAI1 (Bax channel blocker) is a potent inhibitor of Bax-mediated mitochondrial cytochrome C release (IC50: 0.52 μM).
|
TN1406 |
Dihydrokaempferol
|
480-20-6
|
99.51%
|
|
Dihydrokaempferol (Aromadendrin) is a natural product. It induces apoptosis and inhibits Bcl-2 and Bcl-xL expression, possesses anti-inflammatory, antioxidant, a...
|
T17247 |
VU0661013
|
2131184-57-9
|
99.46%
|
|
VU0661013 is an effective and selective inhibitor of MCL-1.
|
T6275 |
Obatoclax Mesylate
|
803712-79-0
|
99.38%
|
|
Obatoclax Mesylate (GX15-070) is a Bcl-2 antagonist (Ki: 0.22 μM) and can induce apoptosis with up-regulation of Bim, induced cytochrome c release, and activatio...
|
T7979 |
2-Hydroxychalcone
|
644-78-0
|
99.38%
|
|
2-Hydroxychalcone (2-(2-Hydroxybenzal)Acetophenone) can be used as antiparasitic hit compounds when Methoxylated.It can inhibit invasion of triple negative breas...
|
T9113 |
Myristicin
|
607-91-0
|
99.34%
|
|
Myristicin (Myristicine) is a natural product found in spices and umbelliferous plants. Myristicin has anti-cholinergic, Antibacterial, and hepatoprotective effe...
|
T2099 |
ABT-737
|
852808-04-9
|
99.3%
|
|
ABT-737 is a BH3 mimetic inhibitor of Bcl-xL, Bcl-2 and Bcl-w (EC50s: 78.7/30.3/197.8 nM).
|
T12629L |
MIK665
|
1799631-75-6
|
99.28%
|
|
MIK665 (S-64315) (S-64315) has an inhibitory effect on myeloid leukemia.
|
T38622 |
Bcl-xL antagonist 2
|
1235032-75-3
|
99.26%
|
|
Bcl-xL antagonist 2 is an effective and selective antagonist of Bcl-xL with an IC50 of 91 nM and a Ki of 65 nM. Bcl-xL antagonist 2 induces apoptosis in cancer c...
|
T2453 |
BAM7
|
331244-89-4
|
99.23%
|
|
BAM 7 is a direct and specific activator of proapoptotic Bax (EC50: 3.3 μM).
|
TN1891 |
Lupiwighteone
|
104691-86-3
|
99.20%
|
|
Lupiwighteone has anti-angiogenesis potential, it also has anticancer and cancer preventive effects on SH-SY5Y cells.
|
T5104 |
BTSA1
|
314761-14-3
|
99.15%
|
|
BTSA1 is a BAX activator that binds with high affinity and specificity to the N-terminal activation site and induces conformational changes to BAX leading to BAX...
|
T1119 |
Rasagiline
|
136236-51-6
|
99.14%
|
|
Rasagiline (AGN1135) is an inhibitor of monamine oxidase used as adjunctive therapy in combination with levodopa and carbidopa in the management of Parkinsons di...
|
T12186 |
Navitoclax-piperazine
|
2143096-93-7
|
99.11%
|
|
Navitoclax-piperazine (ABT-263-piperazine) is an inhibitor of B-cell lymphoma extra large (BCL-XL).
|
T3697 |
3',6-Disinapoylsucrose
|
139891-98-8
|
99.02%
|
|
3',6-Disinapoylsucrose (Disinapoyl sucrose) shows the neuroprotective effect and antidepressive activity in rats.
|
T6881 |
LTX-315
|
1345407-05-7
|
99%
|
|
LTX-315 (Oncopore), the oncolytic peptide, inhibits cancer cells through Bax/Bak-regulated mitochondrial membrane permeabilization.
|
T12824L |
S55746
|
1448584-12-0
|
98.99%
|
|
S55746 (BLC201) is an effective and selective BCL-2 inhibitor (Ki: 1.3 nM and a Kd of 3.9 nM).
|
T4088 |
Thymoquinone
|
490-91-5
|
98.98%
|
|
Thymoquinone (NSC 2228) is a compound be found in herbs and spices with anti-inflammatory and anti-oxidant effects.
|