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ATPase

ATPases ( adenylpyrophosphatase, ATP monophosphatase, triphosphatase, SV40 T-antigen, adenosine 5'-triphosphatase, ATP hydrolase, complex V (mitochondrial electron transport), (Ca2+ + Mg2+)-ATPase, HCO3−-ATPase, adenosine triphosphatase) are a class of enzymes that catalyze the decomposition of ATP into ADP and a free phosphate ion[1][2][3][4][5][6] or the inverse reaction. This dephosphorylation reaction releases energy, which the enzyme (in most cases) harnesses to drive other chemical reactions that would not otherwise occur.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T14965 Ciliobrevin D 1370554-01-0 100%
Ciliobrevin D
Ciliobrevin D is a AAA+ ATPase motor cytoplasmic dynein inhibitor. Ciliobrevin D inhibits Hedgehog (Hh) signaling and primary cilia formation and it also inhibit...
T13159 Tiludronate disodium 149845-07-8 100%
Tiludronate disodium
Tiludronate disodium (Tiludronic acid disodium) is an osteoclast vacuolar H(+)-ATPase inhibitor with antiresorptive and anti-inflammatory properties. Tiludronate...
TN2239 Strictosamide 23141-25-5 100%
Strictosamide
Strictosamide possesses antibacterial and antiviral activities, it also may have important effects on inflammation and inflammatory pain.
T2404 Vonoprazan fumarate 1260141-27-2 100%
Vonoprazan fumarate
Vonoprazan fumarate (TAK-438) is a novel P-CAB (potassium-competitive acid blocker) that reversibly inhibits H+/K+, ATPase.
T0126 Diazoxide 364-98-7 100%
Diazoxide
Diazoxide (Proglycem) is a benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies. It lacks diuretic effect, apparently b...
T6953 Prilocaine 721-50-6 100%
Prilocaine
Prilocaine (NSC-40027) is a local anesthetic of the amino amide type, which acts on the sodium channel on the neuronal membrane and limits the spread of seizures...
T15373 Gboxin 2101315-36-8 100%
Gboxin
Gboxin is an inhibitor of oxidative phosphorylation that targets glioblastoma,inhibits the activity of F0F1 ATP synthase, with antitumour activity.
T0796 Prilocaine hydrochloride 1786-81-8 100%
Prilocaine hydrochloride
Prilocaine hydrochloride (Prilocaine HCl) is a local anesthetic of the amino amide type, binds to voltage-gated sodium ion channels in the neuronal membrane, the...
TN1103 Diphyllin 22055-22-7
Diphyllin
Diphyllin could be characterized as a new V-ATPase inhibitor in treating gastric cancer and inhibiting the phosphorylation of LRP6 in Wnt/β-catenin signaling.
T3432 Cinobufagin 470-37-1
Cinobufagin
Cinobufagin (Cinobufagine) is a selective Na+/K+-ATPase inhibitor. The activity of Cinobufagin is same as ouabain.
T20436 DHQ 15804-19-0
DHQ
DHQ (2,3-dihydroxy-quinoxalin) is an inducer of ATPase activity that of Herpes Simplex Virus thymidine kinase.
T3480 Sudoterb free base 676266-31-2
Sudoterb free base
Sudoterb free base (Sudoterb) , also known as LL3858, is an anti-tubercular drug candidate.
TN3209 3′,4′,7-Trihydroxyflavone  2150-11-0 98%
3′,4′,7-Trihydroxyflavone 
3'4'7-Trihydroxyflavone can markedly inhibit the receptor activator of nuclear factor kappa B ligand (RANKL) induced osteoclastic differentiation from mouse bone...
TN1425 Bacoside A3 157408-08-7 98%
Bacoside A3
Bacoside A3 has antioxidant potential, it shows comparatively higher neuroprotective response analysed as higher cell viability and decreased intracellular ROS.
T2089 Eniporide 176644-21-6 98%
Eniporide
Eniporide is a Na(+)/H(+) exchange inhibitor.
T2621 Rostafuroxin 156722-18-8 98%
Rostafuroxin
Rostafuroxin (PST 2238) has been used in trials studying the treatment of Essential Hypertension.
TN3831 (-)-Denudatin B 87402-88-8 98%
(-)-Denudatin B
(-)-Denudatin B (Denudatin B) is derived from Magnolia fargesii. (-)-Denudatin B has nonspecific antiplatelet action at high concentration by inhibiting phosphoi...
T6587 Mitiglinide Calcium 145525-41-3 98%
Mitiglinide Calcium
Mitiglinide Calcium (KAD-1229) is a blood glucose-lowering drugs, stimulating insulin secretion by closing the ATP-sensitive K+ channels in pancreatic beta-cells...
Ciliobrevin D
T14965
Ciliobrevin D is a AAA+ ATPase motor cytoplasmic dynein inhibitor. Ciliobrevin D inhibits Hedgehog (Hh) signaling and primary cilia formation and it also inhibit...
Tiludronate disodium
T13159
Tiludronate disodium (Tiludronic acid disodium) is an osteoclast vacuolar H(+)-ATPase inhibitor with antiresorptive and anti-inflammatory properties. Tiludronate...
Strictosamide
TN2239
Strictosamide possesses antibacterial and antiviral activities, it also may have important effects on inflammation and inflammatory pain.
Vonoprazan fumarate
T2404
Vonoprazan fumarate (TAK-438) is a novel P-CAB (potassium-competitive acid blocker) that reversibly inhibits H+/K+, ATPase.
Diazoxide
T0126
Diazoxide (Proglycem) is a benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies. It lacks diuretic effect, apparently b...
Prilocaine
T6953
Prilocaine (NSC-40027) is a local anesthetic of the amino amide type, which acts on the sodium channel on the neuronal membrane and limits the spread of seizures...
Gboxin
T15373
Gboxin is an inhibitor of oxidative phosphorylation that targets glioblastoma,inhibits the activity of F0F1 ATP synthase, with antitumour activity.
Prilocaine hydrochloride
T0796
Prilocaine hydrochloride (Prilocaine HCl) is a local anesthetic of the amino amide type, binds to voltage-gated sodium ion channels in the neuronal membrane, the...
Diphyllin
TN1103
Diphyllin could be characterized as a new V-ATPase inhibitor in treating gastric cancer and inhibiting the phosphorylation of LRP6 in Wnt/β-catenin signaling.
Cinobufagin
T3432
Cinobufagin (Cinobufagine) is a selective Na+/K+-ATPase inhibitor. The activity of Cinobufagin is same as ouabain.
DHQ
T20436
DHQ (2,3-dihydroxy-quinoxalin) is an inducer of ATPase activity that of Herpes Simplex Virus thymidine kinase.
Sudoterb free base
T3480
Sudoterb free base (Sudoterb) , also known as LL3858, is an anti-tubercular drug candidate.
3′,4′,7-Trihydroxyflavone 
TN3209
3'4'7-Trihydroxyflavone can markedly inhibit the receptor activator of nuclear factor kappa B ligand (RANKL) induced osteoclastic differentiation from mouse bone...
Bacoside A3
TN1425
Bacoside A3 has antioxidant potential, it shows comparatively higher neuroprotective response analysed as higher cell viability and decreased intracellular ROS.
Eniporide
T2089
Eniporide is a Na(+)/H(+) exchange inhibitor.
Rostafuroxin
T2621
Rostafuroxin (PST 2238) has been used in trials studying the treatment of Essential Hypertension.
(-)-Denudatin B
TN3831
(-)-Denudatin B (Denudatin B) is derived from Magnolia fargesii. (-)-Denudatin B has nonspecific antiplatelet action at high concentration by inhibiting phosphoi...
Mitiglinide Calcium
T6587
Mitiglinide Calcium (KAD-1229) is a blood glucose-lowering drugs, stimulating insulin secretion by closing the ATP-sensitive K+ channels in pancreatic beta-cells...
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TargetMol