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ATPase

ATPases ( adenylpyrophosphatase, ATP monophosphatase, triphosphatase, SV40 T-antigen, adenosine 5'-triphosphatase, ATP hydrolase, complex V (mitochondrial electron transport), (Ca2+ + Mg2+)-ATPase, HCO3−-ATPase, adenosine triphosphatase) are a class of enzymes that catalyze the decomposition of ATP into ADP and a free phosphate ion[1][2][3][4][5][6] or the inverse reaction. This dephosphorylation reaction releases energy, which the enzyme (in most cases) harnesses to drive other chemical reactions that would not otherwise occur.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T2922 Phlorizin 60-81-1 99.58%
Phlorizin
Phlorizin (Phloridzin) is a non-selective SGLT inhibitor found in apple, for hSGLT1( Ki=300 nM) and hSGLT2( Ki=39 nM) .
T15373 Gboxin 2101315-36-8 99.58%
Gboxin
Gboxin is an inhibitor of oxidative phosphorylation that targets glioblastoma,inhibits the activity of F0F1 ATP synthase, with antitumour activity.
T27812 Leminoprazole 104340-86-5 99.56%
Leminoprazole
Leminoprazole is an orally available H+,K(+)-ATPase inhibitor that protects gastric mucosal cells from various cellular damages.
T6834 FCCP 370-86-5 99.5%
FCCP
FCCP (Trifluoromethoxy carbonylcyanide phenylhydrazone), a potent uncoupler of oxidative phosphorylation in mitochondria, transport protons across cell membranes...
T2093L (S)-PF-03716556 928774-44-1 99.49%
(S)-PF-03716556
(S)-PF-03716556 can be used as an acid pump inhibitor for the treatment of disease conditions mediated by acid pump inhibitory activity.
T1137 Clorsulon 60200-06-8 99.44%
Clorsulon
Clorsulon (L631529) is utilized for the treatment of Fasciola hepatica infections in calves and sheep.
T1482 Ciclopirox 29342-05-0 99.41%
Ciclopirox
Ciclopirox (HOE296b) exerts its action by binding to and chelating trivalent cations, such as Fe3+ and Al3+, thereby inhibiting the availability of essential co-...
T0114 Trichlormethiazide 133-67-5 99.32%
Trichlormethiazide
Trichlormethiazide (Naqua) is a short-acting, 3-dichloromethyl derivative of hydrochlorothiazide, belonging to the class of thiazide diuretics. Trichlormethiazid...
T5S0890 Oleandrin 465-16-7 99.31%
Oleandrin
1. Oleandrin (Folinerin), the principal cardiac glycoside component of PBI-524, can quantitatively account for regulation of BDNF at both the protein and transcr...
T6062 Brefeldin A 20350-15-6 99.26%
Brefeldin A
Brefeldin A (Cyanein) , a Penicillium brefeldianum metabolite, which is a macrocyclic lactone exhibiting a wide range of antibiotic activity. It is also an ATPas...
T4190 Ticlopidine 55142-85-3 99.21%
Ticlopidine
Ticlopidine (PCR 5332) is an antiplatelet drug in the thienopyridine family which is an adenosine diphosphate (ADP) receptor inhibitor.
T27371 FR-167356 174185-16-1 99.19%
FR-167356
FR-167356 is a specific inhibitor of a3 isoform vacuolar type H⁺-ATPase with IC50s of 170 nM, 370 nM and 220 nM for osteoclast plasma membranes, renal brush bord...
T2093 PF 03716556 928774-43-0 99.17%
PF 03716556
PF 03716556 (PF-3716556) , an effective and specific P-CAB (potassium-competitive acid blocker), is utilized for the treatment of gastroesophageal reflux disease...
T4861 Trans-Aconitic acid 4023-65-8 99.16%
trans-Aconitic acid
Trans-Aconitic acid is normally present in normal human urine, and it has been suggested that is present in larger amounts with Reye's syndrome and organic acidu...
T2822 Ginsenoside Rb1 41753-43-9 99.12%
Ginsenoside Rb1
Ginsenoside Rb1 (Gypenoside Ⅲ) is part of a class of steroid glycosides; may have properties that inhibit or prevent the growth of tumors.
T13881 Dicirenone 41020-79-5 99.1%
Dicirenone
Dicirenone (SC26304) inhibits the Mineralocorticoid receptor (MR), aldosterone regulation of the urinary K+:Na+ ratio, and aldosterone binding to renal cytoplasm...
T0490 Chlorpropamide 94-20-2 99.01%
Chlorpropamide
Chlorpropamide (Diabinese) is a sulfonylurea hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modifi...
TN2148 Retusin 1245-15-4 99.00%
Retusin
Retusin is derived from the leaves of Talinum triangulare. Retusin Retusin can be used in studies about acting as pre- and postemergent herbicides.
T1114 Ciclopirox olamine 41621-49-2 98.97%
Ciclopirox olamine
Ciclopirox olamine is a broad-spectrum antifungal agent with additional antibacterial and anti-inflammatory activities.
T2686 Esomeprazole Magnesium 161973-10-0 98.84%
Esomeprazole Magnesium
Esomeprazole Magnesium (NEXIUM) is the S-isomer of omeprazole, can reduce gastric acid secretion with selective and irreversible proton pump inhibitor activity.E...
Phlorizin
T2922
Phlorizin (Phloridzin) is a non-selective SGLT inhibitor found in apple, for hSGLT1( Ki=300 nM) and hSGLT2( Ki=39 nM) .
Gboxin
T15373
Gboxin is an inhibitor of oxidative phosphorylation that targets glioblastoma,inhibits the activity of F0F1 ATP synthase, with antitumour activity.
Leminoprazole
T27812
Leminoprazole is an orally available H+,K(+)-ATPase inhibitor that protects gastric mucosal cells from various cellular damages.
FCCP
T6834
FCCP (Trifluoromethoxy carbonylcyanide phenylhydrazone), a potent uncoupler of oxidative phosphorylation in mitochondria, transport protons across cell membranes...
(S)-PF-03716556
T2093L
(S)-PF-03716556 can be used as an acid pump inhibitor for the treatment of disease conditions mediated by acid pump inhibitory activity.
Clorsulon
T1137
Clorsulon (L631529) is utilized for the treatment of Fasciola hepatica infections in calves and sheep.
Ciclopirox
T1482
Ciclopirox (HOE296b) exerts its action by binding to and chelating trivalent cations, such as Fe3+ and Al3+, thereby inhibiting the availability of essential co-...
Trichlormethiazide
T0114
Trichlormethiazide (Naqua) is a short-acting, 3-dichloromethyl derivative of hydrochlorothiazide, belonging to the class of thiazide diuretics. Trichlormethiazid...
Oleandrin
T5S0890
1. Oleandrin (Folinerin), the principal cardiac glycoside component of PBI-524, can quantitatively account for regulation of BDNF at both the protein and transcr...
Brefeldin A
T6062
Brefeldin A (Cyanein) , a Penicillium brefeldianum metabolite, which is a macrocyclic lactone exhibiting a wide range of antibiotic activity. It is also an ATPas...
Ticlopidine
T4190
Ticlopidine (PCR 5332) is an antiplatelet drug in the thienopyridine family which is an adenosine diphosphate (ADP) receptor inhibitor.
FR-167356
T27371
FR-167356 is a specific inhibitor of a3 isoform vacuolar type H⁺-ATPase with IC50s of 170 nM, 370 nM and 220 nM for osteoclast plasma membranes, renal brush bord...
PF 03716556
T2093
PF 03716556 (PF-3716556) , an effective and specific P-CAB (potassium-competitive acid blocker), is utilized for the treatment of gastroesophageal reflux disease...
trans-Aconitic acid
T4861
Trans-Aconitic acid is normally present in normal human urine, and it has been suggested that is present in larger amounts with Reye's syndrome and organic acidu...
Ginsenoside Rb1
T2822
Ginsenoside Rb1 (Gypenoside Ⅲ) is part of a class of steroid glycosides; may have properties that inhibit or prevent the growth of tumors.
Dicirenone
T13881
Dicirenone (SC26304) inhibits the Mineralocorticoid receptor (MR), aldosterone regulation of the urinary K+:Na+ ratio, and aldosterone binding to renal cytoplasm...
Chlorpropamide
T0490
Chlorpropamide (Diabinese) is a sulfonylurea hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modifi...
Retusin
TN2148
Retusin is derived from the leaves of Talinum triangulare. Retusin Retusin can be used in studies about acting as pre- and postemergent herbicides.
Ciclopirox olamine
T1114
Ciclopirox olamine is a broad-spectrum antifungal agent with additional antibacterial and anti-inflammatory activities.
Esomeprazole Magnesium
T2686
Esomeprazole Magnesium (NEXIUM) is the S-isomer of omeprazole, can reduce gastric acid secretion with selective and irreversible proton pump inhibitor activity.E...
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TargetMol