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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TP1035 | Cyclic somatostatin | SRIF-14,Somatostatin-14 | Others |
Cyclic somatostatin (SRIF-14) is a cyclic tetradecapeptide regulating many endocrine and nervous system functions. | |||
T21622 | Tyrphostin A25 | AG-82,Tyrphostin AG 82,RG-50875 | EGFR , GPR |
Tyrphostin A25 (Tyrphostin AG 82) is a specific EGFR tyrosine kinase inhibitor and GPR35 agonist with an IC50 value of 0.94 μM for GPR35 and an EC50 value of 5.3 μM for GPR35. | |||
T25859 | Necrostatin-7 | Necrostatin 7,Necrostatin7,Nec 7,Nec-7,Nec7 | Apoptosis |
Necrostatin-7 (Necrostatin 7) is an inhibitor of necrotic apoptosis with cardioprotective effects, inhibits RANK-NFATc1 signaling, and attenuates macrophage differentiation into osteoblasts. | |||
T9095 | Necrostatin-34 | 2-{[3-cyano-4-(4-methylphenyl)-6-oxo-1,4 | RIP kinase |
Necrostatin-34 (2-{[3-cyano-4-(4-methylphenyl)-6-oxo-1,4) is a RIPK1 kinase inhibitor, stabilizing RIPK1 kinase in an inactive conformation by occupying a distinct binding pocket in the kinase domain. | |||
T7184 | Firsocostat | ND-630,NDI-010976,GS-0976 | Acetyl-CoA Carboxylase |
Firsocostat (GS-0976) is an inhibitor of acetyl-CoA carboxylase (ACC) dimerization that inhibits human ACC1 and ACC2 activity (IC50s of 2.1 and 6.1 nM, respectively) | |||
TP1035L | Cyclic somatostatin Acetate(38916-34-6(free base)) | Somatostatin (sheep), monoacetate (salt),Somatostatin-14,SRIF-14,monoacetate (salt) | Others |
Cyclic somatostatin Acetate(38916-34-6(free base)) (Somatostatin-14) is a cyclic tetradecapeptide regulating many endocrine and nervous system functions. | |||
T27066 | Prostaglandin G/H synthase 1 inhibitor | CP74006,CP 74006,2-Amino-N-(4-chlorophenyl)benzamide | Others |
Prostaglandin G/H synthase 1 inhibitor (CP 74006) is a selective D5D inhibitor with an IC(50) value of 20 nM. | |||
T0598 | Iminostilbene | Dibenzazepine | Others |
Iminostilbene (Dibenzazepine) (Dibenzazepine) is a chemical precursor of carbamazepine which is used primarily in the treatment of epilepsy and neuropathic pain. | |||
T3510 | Olumacostat Glasaretil | Acetyl-CoA Carboxylase | |
Olumacostat glasaretil is a small molecule inhibitor of acetyl coenzyme A carboxylase (ACC). It has been used in trials studying the treatment of Acne Vulgaris. | |||
T4532 | Linrodostat | BMS-986205 | IDO , Indoleamine 2,3-Dioxygenase (IDO) |
Linrodostat (BMS-986205) is a selective indoleamine 2, 3-dioxygenase 1 (IDO1) inhibitor. | |||
T0431 | Abexinostat | CRA 24781,PCI24781,PCI-24781,PCI 24781,CRA 024781 | HDAC |
PCI-24781 (Abexinostat (PCI24781)) is a new pan-HDAC inhibitor mainly targeting HDAC1 (Ki: 7 nM), also have moderate inhibitory for HDACs 2, 3, 6, and 10 and greater than 40-fold selectivity against HDAC8. Phase 1/2. | |||
T27828 | Licostinel | CGP 63446,ACEA1021,ACEA 1021,ACEA-1021,CGP-63446 | GluR |
Licostinel (CGP 63446) is a glutamate receptor antagonist. Licostinel protects against permanent focal cerebral ischemia. | |||
T40199 | Tulmimetostat | CPI-0209 | Histone Methyltransferase |
Tulmimetostat (CPI-0209) is an orally active EZH1/EZH2 inhibitor.Tulmimetostat has antitumor activity and is used in the study of ovarian cancer and advanced solid tumors. | |||
T77627 | Opevesostat | ODM208,ODM-208 | P450 |
Opevesostat (ODM-208) is an inhibitor of lyase (CYP11A1) (the enzyme cleavage cholesterol side chain). | |||
T6381 | Amifostine trihydrate | Ethyol trihydrate,WR2721,Amifostine | Others , HIF/HIF Prolyl-Hydroxylase |
Amifostine trihydrate (WR2721) is the first approved radioprotective drug, used to decrease the risk of kidney problems caused by treatment with cisplatin. | |||
T2397 | Topiroxostat | FYX-051 | P450 , ROS , Xanthine Oxidase |
Topiroxostat (FYX-051) is a selective xanthine oxidase inhibitor developed for treatment and management of hyperuricemia and gout. | |||
T2479 | Tyrphostin A9 | Malonoben,Tyrphostin 9,SF 6847,AG 17,RG-50872 | EGFR , VEGFR , Influenza Virus , PDGFR |
Tyrphostin A9 (SF 6847) is an Agricultural acaricide, now superseded. Tyrphostin A9 is firstly designed as an EGFR inhibitor | |||
T2392 | Nafamostat mesylate | FUT-175 | Apoptosis , Serine/threonin kinase , SARS-CoV , Serine Protease |
Nafamostat mesylate (FUT-175), a synthetic serine protease inhibitor, has been used for the treatment of allergic disorders such as asthma, allergic rhinitis and atopic dermatitis. | |||
T1899 | Pyridostatin | RR82,Pyridostatin Trifluoroacetate Salt | DNA/RNA Synthesis |
Pyridostatin (RR82) is a synthetic small-molecule stabilizer of G-quadruplexes, a secondary structure of DNA that usually exists in the end of the chromosome or the telomeres. | |||
T67707 | Tyrphostin AG 538 | AG 538 | IGF-1R |
Tyrphostin AG 538 is a chalcone compound, an IGF-1 receptor kinase inhibitor (IC₅0 : for 400 nM) that is potent, cell-permeable, reversible, and competitive. | |||
T60522 | Letosteine | Viscotiol | Others |
Letosteine (Viscotiol) is an orally active, effective, and safe expectorant that can be used in the study of acute or chronic respiratory diseases, for example, bronchopulmonary disease. Letosteine dissolves bronchial mu... | |||
TP1658L | Type A Allatostatin I acetate | Type A Allatostatin I acetate(123209-95-0 free base) | Others |
Type A Allatostatin I acetate is a tridecapeptide. Allatostatins are pleiotropic neuropeptides for inhibition of juvenile hormone synthesis in insects. | |||
T6711 | Tyrphostin AG1296 | Tyrphostin AG 1296,AG 1296 | Apoptosis , FGFR , FLT , PDGFR , c-Kit |
Tyrphostin AG1296 (Tyrphostin AG 1296) is an inhibitor of PDGFR with IC50 of 0.3-0.5 μM, no activity to EGFR. | |||
T9170 | Testosterone decanoate | Others | |
Subcutaneous etonogestrel can be used for birth control. | |||
T2512 | Mocetinostat | MGCD0103,MG0103 | Apoptosis , HDAC , Autophagy |
Mocetinostat (MG0103) is an orally available HDAC inhibitor with most potency for HDAC1 (IC50: 0.15 μM), 2- to 10- fold selectivity against HDAC2/3/11. | |||
T4370 | Resminostat hydrochloride | 4SC-201 hydrochloride,RAS2410 hydrochloride | HDAC |
Resminostat hydrochloride (RAS2410 hydrochloride) is an effective inhibitor of HDAC1/HDAC3/HDAC6 (IC50: 42.5/50.1/71.8 nM), respectively, and shows less potent activities against HDAC8 (IC50: 877 nM). | |||
T5862 | Ezatiostat TFA | TER199(free base),Ezatiostat TFA (free base),Ezatiostat,TLK199 | GST |
Ezatiostat TFA (TLK199) is a liposomal small-molecule glutathione analog inhibitor of glutathione S-transferase (GST) P1-1 with hematopoiesis-stimulating activity. | |||
T0780 | Pyridostigmine bromide | Mestinon | AChE |
Pyridostigmine bromide (Mestinon) is a cholinesterase inhibitor with a slightly longer duration of action than NEOSTIGMINE. It is used in the treatment of myasthenia gravis and to reverse the actions of muscle relaxants. | |||
T4042 | Talabostat mesylate | Val-boroPro,PT100 | Proteasome , DPP-4 |
Talabostat mesylate (PT100) is an orally active, selective inhibitor of dipeptidyl peptidases IV (DPP4, IC50: 0.18 nM), including tumor-associated fibroblast activation protein. This agent may also stimulate the producti... | |||
T4470 | Pyridostatin TFA | DNA/RNA Synthesis | |
Pyridostatin Trifluoroacetate Salt is a G-quadruplexe stabilizer with Kd of 490 nM in a cell-free assay, which targets a series of proto-oncogenes including c-kit, K-ras and Bcl-2. | |||
T6115 | Fostamatinib | R788 | FLT , Syk , Monoamine Transporter , Adenosine Receptor |
Fostamatinib (R788)(IC50 of 41 nM), which is a prodrug of the active metabolite R406, is a Syk inhibitor. It does not work on Lyn. | |||
T21224 | (+)-Fluprostenol | Fluprostenol, (+)-,Travoprost acid,AL-5848 | Prostaglandin Receptor |
(+)-Fluprostenol (AL-5848), an analogue of prostaglandin F2 alpha, is a prostaglandin F2α receptor PTGFR agonist and decreases the expression of Oviductal glycoprotein 1 (OVGP1). | |||
T3211 | Midostaurin | N-Benzoylstaurosporine,PKC412,CGP41231,CGP 41251 | Others , PKC |
PKC412(Midostaurin (PKC412); CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor. Midostaurin inhibits protein kinase C alpha (PKCalpha), vascular endothelial growth factor receptor 2 (VEGFR2), c-kit, platel... | |||
T9035 | Testosterone undecanoate | Others , Androgen Receptor | |
Testosterone undecanoate is a metabolite of Testosterone, which is a promising androgen for male hormonal contraception. | |||
T15719 | Latanoprostene bunod | LBN,NCX116 | Others |
Latanoprostene bunod (LBN) is nitric oxide (NO)-donating prostaglandin F2a analog and is a topical ophthalmic therapeutic. It is used for the reduction of intraocular pressure (IOP) in patients with open-angle glaucoma o... | |||
T4006 | Pentostatin | Nipent,CI-825,Covidarabine,Deoxycoformycin | Adenosine deaminase , Adenosine Receptor |
Pentostatin (CI-825) is an extremely effective and irreversible inhibitor of adenosine deaminase (Ki: 2.5 pM). | |||
T6307 | Lubiprostone | SPI-0211,RU-0211 | Chloride channel |
Lubiprostone (RU-0211), an activator of ClC-2 chloride channels, is used in the therapy of idiopathic chronic constipation. | |||
T60625 | Tigulixostat | LR-19074,IBI-350,LC350189 | Xanthine Oxidase |
Tigulixostat (LC350189) is a novel xanthine oxidase inhibitor (XOI) that reduces uric acid production and may be used to study gout-related diseases. | |||
T0773 | Febuxostat | TMX 67,TEI 6720 | ROS , Xanthine Oxidase |
Febuxostat (TEI 6720) is a xanthine oxidase Inhibitor. | |||
T61562 | CB1R Allosteric modulator 3 | cAMP , Cannabinoid Receptor | |
CB1R Allosteric modulator 3 is a potent CB1R modulator.CB1R Allosteric modulator 3 inhibits cAMP and β-Arrestin, and can be used for the study of obesity and nicotine addiction. | |||
T1583 | Vorinostat | MK0683,suberoylanilide hydroxamic acid,SAHA | Apoptosis , Mitophagy , Virus Protease , HDAC , Autophagy |
Vorinostat (SAHA) is a pan-histone deacetylase (HDAC) inhibitor (IC50=10 nM) with inhibitory activity against HDAC1/2/3/6/7/11. Vorinostat has antitumor activity, induces cell differentiation, blocks the cell cycle and i... | |||
T34973 | Tyrphostin 8 | 4-Hydroxybenzylidenemalononitrile | EGFR , GTPase |
Tyrphostin 8(4-Hydroxybenzylidenemalononitrile) is a potent GTPase inhibitor that inhibits EGFR kinase with an IC50 of 560 μM.Tyrphostin 8 inhibits protein serine/threonine calmodulin phosphatases (IC50=21 μM), enhances ... | |||
T72482 | Dazostinag disodium | STING | |
Dazostinag disodium (TAK-676) is a novel stimulator of interferon genes (STING) agonist and immune system modulator with antitumor activity that activates dendritic cells, natural killer cells, and T cells. | |||
T1847 | Necrostatin-1 | Nec-1,Necrostatin 1 | Indoleamine 2,3-Dioxygenase (IDO) , Ferroptosis , Autophagy , RIP kinase |
Necrostatin-1 (Nec-1) is a necrotic apoptosis inhibitor and RIP1 inhibitor with specificity. Necrostatin-1 inhibits TNF-α-induced necrotic apoptosis. Necrostatin-1 also inhibits IDO. | |||
T2078 | Fimepinostat | CUDC-907,PI3K/HDAC Inhibitor,CUDC 907 | Apoptosis , PI3K , HDAC |
Fimepinostat (CUDC 907) is an orally bioavailable inhibitor of both phosphoinositide 3-kinase (PI3K) class I and pan-histone deacetylase (HDAC) enzymes, with potential antineoplastic activity. Upon oral administration, C... | |||
TQ0133 | Amifostine thiol dihydrochloride | WR 1065 | p53 |
Amifostine thiol dihydrochloride (WR 1065) can activate p53 through a JNK-dependent signaling pathway. It also protects normal tissues from the toxic effects of certain cancer drugs. | |||
T13238 | Tyrphostin AG1433 | SU1433,AG1433 | VEGFR , PDGFR |
Tyrphostin AG1433 (AG1433) is an inhibitor of tyrosine kinases and also a dual inhibitor of PDGFRβ(IC50s = 5.0 μM) and VEGFR-2 (Flk-1/KDR)(IC50s = 9.3 μM). | |||
T7642 | Cilostamide | OPC3689 | PDE |
Cilostamide (OPC3689) is a selective phosphodiesterase (PDE)3A and PDE3B inhibitor(IC50 values of 27 and 50 nM, respectively) | |||
T11593 | I-OMe-Tyrphostin AG 538 | I-OMe-AG 538 | IGF-1R , PI3K |
I-OMe-Tyrphostin AG 538 is a specific IGF-1R inhibitor and ATP-competitive inhibitor of PI5P4Kα (IC50: 1 µM).I-OMe-Tyrphostin AG 538 inhibits IGF-1R-mediated signaling and exhibits preferential cytotoxicity to nutrient-d... | |||
T27083 | Crebinostat | Epigenetic Reader Domain , Histone Acetyltransferase , HDAC | |
Crebinostat is a potent histone deacetylase (HDAC) inhibitor, inhibiting HDAC1, HDAC2, HDAC3, and HDAC6 with IC50s of 0.7 nM, 1.0 nM, 2.0 nM, and 9.3 nM, respectively.Crebinostat increases the density of synapsin-1 punct... |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TN2546 | 1-Isomangostin | NF-κB | |
1-Isomangostin has cytotoxic and anticomplementary activities. | |||
TN1019 | Beta-mangostin | β-Mangostin | Apoptosis , Antibacterial , Parasite |
Beta-mangostin (β-Mangostin) is a xanthone compound with antibacterial and antimalarial activities. Beta-mangostin present in Cratoxylum arborescens and exhibits antimycobacterial activity against Mycobacterium tuberculo... | |||
T3755 | Pinostilbene | Others | |
Pinostilbene obviously attenuates the phosphorylation of c-Jun and JNK triggered by 6-OHDA. | |||
TN1120 | Osthenol | MAO , Monoamine Oxidase | |
Osthenol is a natural product, and is selective, reversible, and competitive human monoamine oxidase-A (hMAO-A) inhibitor (Ki=0.26 µM).It shows antitumor-promoting activity, it also has antifungal and antibacterial activ... | |||
T2912 | Ergosterol | Provitamin D,Ergosterin,Provitamin D2 | Others , Endogenous Metabolite |
Ergosterol (Provitamin D2) is a steroid extracted from Ganoderma lucidum cystocarp. | |||
T4970 | LANOSTEROL | 3β-Hydroxy-8,24-lanostadiene,8,24-Lanostadien-3β-ol | Endogenous Metabolite |
Lanosterol (3β-Hydroxy-8,24-lanostadiene) is a tetracyclic triterpenoid which is the compound from which all steroids are derived. | |||
TC0027 | Beta-Sitosterol acetate | Others | |
Beta-sitosterol is one of several plant-based substances known as phytosterols. | |||
TC0026 | Testosterone benzoate | Others | |
Testosterone benzoate is a synthetic, injected anabolic androgenic steroid (AAS) and an androgen ester specifically | |||
TN7132 | 4,12-Dimethoxy-6-(7,8-dihydroxy-7,8-dihydrostyryl)-2-pyrone | Others | |
4,12-Dimethoxy-6-(7,8-dihydroxy-7,8-dihydrostyryl)-2-pyrone is a microbial metabolism of yangonin, a major styryl lactone from Piper methysticum. | |||
TN6718 | Dehydrocostuslactone | Others | |
Dehydrocostuslactone is a natural product extracted from Aucklandia.It has wide spectrum of biological effects, including anti-inflammatory, anticancer, antiviral, antimicrobial, antifungal, antioxidant, antidiabetic, an... | |||
T2966 | Beta-Sitosterol | Cupreol,Beta-Sitosterol,β-Sitosterol,Azuprostat,SKF 14463,22,23-Dihydrostigmasterol,Betaprost | Apoptosis , Lipase , Endogenous Metabolite |
Beta-Sitosterol (SKF 14463) has recently been shown to induce G2/M arrest, endoreduplication, and apoptosis through the Bcl-2 and PI3K/Akt signaling pathways. Beta-Sitosterol (SKF 14463) , a main dietary phytosterol foun... | |||
T3871 | Daucosterol | Alexandrin,Sitogluside,β-Sitosterol β-D-glucoside,Eleutheroside A | Glucosidase |
Daucosterol (Sitogluside) has proliferation-enhancing activity, may be involved in the IGF1-AKT pathway. Daucosterol(β-Sitosterol β-D-glucoside) has efficient and inexpensive neuroprotectant effect, to contribute to IGF1... | |||
T3033 | Deoxycorticosterone acetate | DOC acetate,Cortexone acetate,11-Deoxycorticosterone acetate | Glucocorticoid Receptor , Endogenous Metabolite , Adrenergic Receptor |
Deoxycorticosterone acetate (Cortexone acetate) is the 21-acetate derivative of desoxycorticosterone, used for intramuscular injection for replacement therapy of the adrenocortical steroid. | |||
T3130 | Testosterone phenylpropionate | Testosterone hydrocinnamate,Retandrol,Testosterone 17-phenylpropionate | Others |
Testosterone phenylpropionate (Testosterone 17-phenylpropionate)is a steroid indicated for testosterone replacement therapy in sterilization, missing testicle, hypopituitarism, and osteoporosis. | |||
T2888 | Pterostilbene | Autophagy | |
Pterostilbene is extracted from Pterocarpus indicus. | |||
T1626 | Prostaglandin E1 | PGE1,Alprostadil | Endogenous Metabolite , Prostaglandin Receptor |
Prostaglandin E1 (Alprostadil) is the naturally occurring prostaglandin E1 (PGE1) which displays a variety of pharmacologic actions. Prostaglandin E1 is a potent vasodilator agent that increases peripheral blood flow, in... | |||
T20302 | Deoxycorticosterone | Desoxycorticosterone,Desoxycorticosteronum,Desoxycortone | Endogenous Metabolite |
Deoxycorticosterone (Desoxycortone) is a steroid metabolite produced by the adrenal gland. Deoxycorticosterone is an aldosterone precursor and possesses mineralocorticoid activity. | |||
T15133 | Dinoprost | Prostaglandin F2a,PGF2α | Endogenous Metabolite |
Dinoprost (Prostaglandin F2a) is a naturally occurring prostaglandin. It is used in medicine to induce labor and as an abortifacient. | |||
T6528 | Gynostemma Extract | Gypenoside IX,Gypenoside,Gynostemma Pentaphyllum,Notoginsenoside Fd,Ginsenoside C-Mx1,Gynosaponin I | Others , Endogenous Metabolite |
Gynostemma Extract (Gypenoside IX) is a saponins extract derived from the Gynostemma pentaphyllum. | |||
T6270 | Trichostatin A | TSA | HDAC |
Trichostatin A (TSA) is a natural derivative of diene isohydroxamic acids. Trichostatin A is a histone deacetylase inhibitor (IC50=1.8 nM) that is reversible and specific. Trichostatin A leads to the hyperacetylation of ... | |||
TN6737 | (25R)-Spirost-4-ene-3,12-dione | Others | |
(25R)-Spirost-4-ene-3,12-dione is a natural product. | |||
T6S0084 | Tuberostemonine | Tuberstemonine | Parasite |
1. Tuberostemonine (Tuberstemonine) exhibits relatively higher intestinal permeabilities. 2. Tuberostemonine acts in part as an open-channel blocker at the crayfish neuromuscular junction. | |||
T2S1635 | 3-Isomangostin | MTH1 | |
3-Isomangostin is a potent human aldose reductase inhibitor with an IC50 of 3.48 uM; it is also an acetylcholinesterase selective inhibitor. 3-Isomangostin has free radical scavenging activity; it shows antiplasmodial ac... | |||
TN1129 | Protostemotinine | Others | |
Protostemotinine is a natural product from Stemona japonica. | |||
T4953 | Neotuberostemonine | NOS | |
Neotuberostemonine (NTS) is one of the main antitussive alkaloids in the root of Stemona tuberosa Lour, it has a significant protective effect on bleomycin (BLM)-induced pulmonary fibrosis through suppressing the recruit... | |||
TN2082 | Pinostrobin | Beta Amyloid , IL Receptor , Serine/threonin kinase , TNF | |
Pinostrobin, a potent flavonoid inducer, exerts a neuroprotective effect against Aα²(25-35)-induced neurotoxicity in PC12 cells, at least in part, via inhibiting oxidative damage and calcium overload, as well as suppress... | |||
T15720 | Lathosterol | Endogenous Metabolite | |
Lathosterol, a molecule akin to cholesterol, serves as a biomarker for the body's total cholesterol synthesis, as indicated by its serum concentration. | |||
T3S0895 | Spirostan-3-ol | Sarsaponin | Others |
Spirostan-3-ol (Sarsaponin) is a stereoisomer of Sarsasapogenin (S142505), a steroid glycoside isolated from plant materials. A saponin with with potential anti-tumor activity via apoptosis. | |||
TN4919 | Rosthornin A | Others | |
Rosthornin A is a kind of natural product derived from the herbs of Rabdosia rosthornii. | |||
T3332 | Isosteviol | (-)-Isosteviol | IL Receptor , Potassium Channel , TNF , NF-κB , Reactive Oxygen Species , COX , Topoisomerase |
Isosteviol ((-)-Isosteviol), a common natural sweetener, belongs to tetracyclic diterpene glycosides. The pharmacology researches have suggested that stevioside and its hydrolysis products, steviol, isosteviol and stevio... | |||
TN7127 | 5,6-Epoxyergosterol | Others | |
5,6-Epoxyergosterol is derived from the endophytic fungus Phyllosticta capitalensis. | |||
TN7071 | Ergosterol Acetate | Ergosta-5,7,22-trien-3-beta-yl acetate | Others |
Ergosterol Acetate (Ergosta-5,7,22-trien-3-beta-yl acetate) is one of the acetate derivatives of Ergosterol from Monascus anka. | |||
T4S1637 | Gamma-Mangostin | Normangostin | Others , 5-HT Receptor |
1. gamma-Mangostin (Normangostin) as a preventive agent of the metabolic syndrome. 2. Gamma-Mangostin has free radical scavenging activity, and antiproliferative and apoptotic activity in HepG2 cells. 3. Gamma-Mangostin ... | |||
T2848 | Osthole | Osthol,NSC 31868,Ostol | Apoptosis , HBV , Parasite , Histamine Receptor |
Osthole (Osthol), a potential inhibitor of histamine H1 receptor, has been shown to stimulate osteoblast proliferation and differentiation. | |||
T2S2382 | 3'-Hydroxypterostilbene | 3'-HPT | Apoptosis , Autophagy |
3'-Hydroxypterostilbene (3'-HPT), a natural pterostilbene analogue, effectively inhibits the growth of human colon cancer cells with IC50s of 9.0, 40.2, and 70.9 μM for COLO 205, HCT-116, and HT-29 cells, respectively, b... | |||
T0130 | Physostigmine Salicylate | AChR , AChE | |
Physostigmine, a parasympathomimetic alkaloid, is a reversible cholinesterase inhibitor. It extracts from the Calabar bean. | |||
TC0025 | Testosterone acetate | NSC523836,NSC-523836,NSC 523836 | Others |
Testosterone acetate (NSC-523836) is a hormone with in vitro antitumor activity. | |||
T2902 | Costunolide | Costus lactone,NSC 106404,Costunolid,(+)-Costunolide | Apoptosis , Endogenous Metabolite , Telomerase |
Costunolide (Costus lactone) has anti-inflammatory and anti-oxidant properties and mediates apoptosis. | |||
T1214 | Ribostamycin sulfate | Vistamycin sulfate | Antibacterial , Antibiotic |
Ribostamycin sulfate (Vistamycin sulfate) , an aminoglycoside antibiotic, contains a neutral sugar moiety and is produced by Streptomyces ribosome. | |||
T19711 | Desmosterol | Desmesterol,24-Dehydrocholesterol | Endogenous Metabolite |
Desmosterol (24-Dehydrocholesterol) is a cholesterol biosynthesis intermediate that inhibits macrophage inflammatory vesicle activation and prevents vascular inflammation and atherosclerosis. | |||
T2833 | Dehydrocostus Lactone | Epiligulyl oxide,(-)-Dehydrocostus lactone | IκB/IKK |
Dehydrocostus Lactone ((-)-Dehydrocostus lactone) shows anti-inflammatory, anti-ulcer, immunomodulatory and anti-tumor properties. | |||
T1717 | Alpha-Mangostin | α-Mangostin,Mangostin | Apoptosis , Virus Protease , Dehydrogenase , Reactive Oxygen Species , Antibacterial , Antifungal |
alpha-Mangostin (Mangostin) is a natural xanthonoid, a type of organic compound isolated from various parts of the mangosteen tree. | |||
T7990 | 9-hydroxy-4-androstene-3,17-dione | Others | |
9-hydroxy-4-androstene-3,17-dione is a steroid hormone. It has anti-tumor activity and can inhibit the growth of many types of cancer cells, including breast, prostate and lung cancer cells. | |||
TN7112 | (25R)-3β,17α-dihydroxy-5α- spirostan-6-one3-O-α-L- rhamnopyranosyl-(1→2)-β- D-glucopyranoside | Others | |
(25R)-3β,17α-dihydroxy-5α- spirostan-6-one3-O-α-L- rhamnopyranosyl-(1→2)-β- D-glucopyranoside is a natural product isolated from the bulbs of Lilium brownii var. viridulum. | |||
T20939 | Bimatoprost acid | 17-phenyl trinor PGF2α,17-phenyl trinor Prostaglandin F2α | GPR |
Bimatoprost acid (17-phenyl trinor PGF2α) is a metabolically stable analog of PGF2α and has a potential antagonistic activity for the FP receptor. It has a relative potency of 756% compared to PGF2α for binding to the FP... | |||
T26366 | Dehydroepiandrosterone sulfate | PB 005,PB005,Prasterone sulfate,DHEA sulfate,DHEAS,PB-005 | Others |
Dehydroepiandrosterone sulfate (PB-005) influences the migration of neurons, arborization of dendrites, and formation of new synapses. | |||
T14865 | Carboprost tromethamine | Prostaglandin Receptor | |
Carboprost tromethamine, a synthetic 15-methyl analogue of prostaglandin F2α, effectively promotes uterine contractions and significantly reduces bleeding during and post-delivery. | |||
T1679 | Thiostrepton | Thiactin,Bryamycin,Alaninamide | DNA/RNA Synthesis , Antibacterial , Antibiotic |
Thiostrepton (Alaninamide) is a one of the CYCLIC PEPTIDES from Streptomyces that is active against gram-positive bacteria. In veterinary medicine, it has been used in mastitis caused by gram-negative organisms and in de... | |||
TN6736 | Dihydrolanosterol | 24,25-Dihydrolanosterol,Lanostenol | Others |
Dihydrolanosterol (24,25-Dihydrolanosterol) is a sterol and the C24-25 hydrogenated products of lanosterol, dihydrolanosterol can be demethylated by mammal or yeast cytochrome P450 sterol 14alpha-demethylase | |||
TQ0203 | Tafluprost | MK2452,AFP-168 | Prostaglandin Receptor |
Tafluprost, a prostaglandin analog, is the selective agonist of fluoroprostaglandin (FP) receptor PGF2α. | |||
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Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-02050 | DDOST Protein, Human, Recombinant | Human | E. coli |
The enzyme oligosaccharyltransferase (dolichyl-diphosphooligosaccharide-protein glycosyltransferase) (DDOST), or 48-kDa subunit (OST48) is one of the catalytic subunits in this complex, exerts a typical type I membrane t... | |||
TMPJ-01466 | Osteoprotegerin Protein, Human, Recombinant (aa 22-401, His) | Human | HEK293 Cells |
TNFRSF11B is a secreted protein, containing 2 death domains and 4 TNFR-Cys repeats. TNFRSF11B is a decoy receptor for the receptor activator of nuclear factor kappa B ligand (RANKL). By binding RANKL, TNFRSF11B inhibits ... | |||
TMPY-01020 | Periostin/OSF-2 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Periostin/OSF-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 86.4 kDa and the accession number is Q15063-3. | |||
TMPY-03014 | Osteoactivin/GPNMB Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Osteoactivin/GPNMB Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 54.9 kDa and the accession number is Q99P91. | |||
TMPY-01633 | SOST Protein, Rat, Recombinant (His) | Rat | HEK293 Cells |
SOST Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 23 kDa and the accession number is A6HJF6. | |||
TMPY-01288 | Osteopontin Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Osteopontin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35 kDa and the accession number is A0A024RDE2. | |||
TMPY-01613 | Periostin/OSF-2 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Periostin/OSF-2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 89 kDa and the accession number is Q62009-2. | |||
TMPY-04487 | Osteomodulin Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Osteomodulin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 48.6 kDa and the accession number is Q99983. | |||
TMPY-00925 | SOST Protein, Human, Recombinant (His) | Human | HEK293 Cells |
SOST Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.5 kDa and the accession number is Q9BQB4-1. | |||
TMPY-06988 | Osteopontin Protein, Human, Recombinant (aa 17-166, His) | Human | HEK293 Cells |
Osteopontin Protein, Human, Recombinant (aa 17-166, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.64 kDa. and the accession number is P10451. | |||
TMPY-03120 | Prostaglandin D2 Synthase Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Prostaglandin D2 Synthase Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.1 kDa and the accession number is P41222. | |||
TMPJ-01467 | Oncostatin M/OSM Protein, Human, Recombinant (E. coli, His) | Human | E. coli |
Oncostatin M (OSM) is a glycoprotein belonging to the interleukin-6 family of cytokines that includes leukemia-inhibitory factor, granulocyte colony-stimulating factor, and interleukin 6. OSM encodes a growth regulator, ... | |||
TMPH-00324 | SVTLE Protein, Calloselasma rhodostoma, Recombinant (His) | Calloselasma rhodostoma | P. pastoris (Yeast) |
SVTLE Protein, Calloselasma rhodostoma, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 28.6 kDa and the accession number is P26324. | |||
TMPH-00407 | PBP1a Protein, Clostridium botulinum, Recombinant (His & SUMO) | Clostridium botulinum | E. coli |
PBP1a Protein, Clostridium botulinum, Recombinant (His & SUMO) is expressed in E. coli. | |||
TMPH-00412 | BoNT/D Protein, Clostridium botulinum, Recombinant (B2M & His) | Clostridium botulinum | E. coli |
BoNT/D Protein, Clostridium botulinum, Recombinant (B2M & His) is expressed in E. coli expression system with N-6xHis-B2M tag. The predicted molecular weight is 64.5 kDa and the accession number is P19321. | |||
TMPH-03367 | SOSTDC1 Protein, Rat, Recombinant (His & Myc) | Rat | HEK293 Cells |
Directly antagonizes activity of BMP2, BMP4, BMP6 and BMP7 in a dose-dependent manner. May be involved in the onset of endometrial receptivity for implantation/sensitization for the decidual cell reaction. Enhances Wnt s... | |||
TMPH-03066 | PatA Protein, Nostoc sp., Recombinant (His & Myc) | Nostoc | E. coli |
Controls heterocyst pattern formation. Required for the differentiation of intercalary heterocysts but not for terminal heterocysts. | |||
TMPH-02508 | Angiogenin-4 Protein, Mouse, Recombinant (His & SUMOstar) | Mouse | P. pastoris (Yeast) |
Has bactericidal activity against E.faecalis and L.monocytogenes, but not against L.innocua and E.coli. Promotes angiogenesis (in vitro). Has low ribonuclease activity (in vitro). Promotes proliferation of melanoma cells... | |||
TMPY-05069 | Prostaglandin D2 Synthase Protein, Rat, Recombinant (His) | Rat | HEK293 Cells |
Prostaglandin D2 Synthase Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.3 kDa and the accession number is A6JT70. | |||
TMPY-04509 | Osteoprotegerin Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
Osteoprotegerin Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 70.2 kDa and the accession number is O08712. | |||
TMPH-02420 | APOC3 Protein, Cynomolgus, Recombinant (His & SUMOstar) | Cynomolgus | P. pastoris (Yeast) |
APOC3 Protein, Cynomolgus, Recombinant (His & SUMOstar) is expressed in yeast with N-6xHis-SUMOSTAR tag. The predicted molecular weight is 24.7 kDa and the accession number is P18659. | |||
TMPY-02627 | Oncostatin M/OSM Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Oncostatin M/OSM Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22 kDa and the accession number is P53347. | |||
TMPH-03683 | Varicella-zoster virus (strain Oka vaccine) glycoprotein H/gH Protein (His) | HHV-3 | E. coli |
The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell. Following initial binding to host receptor, membrane fusion is mediated by... | |||
TMPY-04624 | Prostaglandin D2 Synthase Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Prostaglandin D2 Synthase Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 19.9 kDa and the accession number is O09114-1. | |||
TMPH-03685 | Varicella-zoster virus (strain Oka vaccine) glycoprotein L/gL Protein (His & Myc) | HHV-3 | E. coli |
The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell. Acts as a functional inhibitor of gH and maintains gH in an inhibited form... | |||
TMPY-00283 | Oncostatin M/OSM Protein, Human, Recombinant | Human | HEK293 Cells |
Oncostatin M/OSM Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 22.16 kDa and the accession number is P13725. | |||
TMPH-00415 | BoNT/E Protein, Clostridium butyricum, Recombinant (His & SUMO) | Clostridium butyricum | E. coli |
BoNT/E Protein, Clostridium butyricum, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 63.7 kDa and the accession number is P30995. | |||
TMPK-00146 | Oncostatin M/OSM Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
Oncostatin M/OSM Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 25.1 kDa and the accession number is P13725. | |||
TMPH-00320 | Snaclec rhodocytin subunit alpha Protein, Calloselasma rhodostoma, Recombinant (His) | Calloselasma rhodostoma | P. pastoris (Yeast) |
Elicits platelet aggregation by the binding to the C-type lectin domain family 1 member B (CLEC1B/CLEC2). Binding leads to tyrosine phosphorylation in the cytoplasmic tail of CLEC1B, which promotes the binding of spleen ... | |||
TMPH-00408 | ClpP Protein, Clostridium botulinum, Recombinant (His & SUMO) | Clostridium botulinum | E. coli |
ClpP Protein, Clostridium botulinum, Recombinant (His & SUMO) is expressed in E. coli. | |||
TMPH-01603 | Lanosterol synthase/LSS Protein, Human, Recombinant (His) | Human | E. coli |
Key enzyme in the cholesterol biosynthesis pathway. Catalyzes the cyclization of (S)-2,3 oxidosqualene to lanosterol, a reaction that forms the sterol nucleus. Through the production of lanosterol may regulate lens prote... | |||
TMPH-00411 | BoNT/C Protein, Clostridium botulinum, Recombinant (His & SUMO) | Clostridium botulinum C phage | E. coli |
BoNT/C Protein, Clostridium botulinum, Recombinant (His & SUMO) is expressed in E. coli. | |||
TMPY-05113 | SOST Protein, Human, Recombinant (His), Biotinylated | Human | HEK293 Cells |
SOST Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.5 kDa and the accession number is Q9BQB4-1. | |||
TMPH-00477 | NDK, cytosolic Protein, Dictyostelium discoideum, Recombinant (His & V5) | Dictyostelium discoideum | E. coli |
NDK, cytosolic Protein, Dictyostelium discoideum, Recombinant (His & V5) is expressed in E. coli. | |||
TMPY-02155 | Prostatic Acid Phosphatase Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Prostatic Acid Phosphatase Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42 kDa and the accession number is P15309-2. | |||
TMPK-00576 | Oncostatin M/OSM Protein, Canine, Recombinant (His) | Canine | HEK293 Cells |
Oncostatin M/OSM Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 21.65 kDa and the accession number is A0A8I3Q5M1. | |||
TMPK-00807 | Osteopontin Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Secreted phosphoprotein 1 (SPP1) expression in TAMs isolated from lung adenocarcinoma tissues and PMA-treated THP-1 cells were measured. Macrophage polarization was identified by flow cytometric analysis. Cell migration ... | |||
TMPH-02765 | LY6C1 Protein, Mouse, Recombinant (His & SUMOstar) | Mouse | P. pastoris (Yeast) |
N/A. LY6C1 Protein, Mouse, Recombinant (His & SUMOstar) is expressed in yeast with N-6xHis-SUMOSTAR tag. The predicted molecular weight is 25.1 kDa and the accession number is P0CW02. | |||
TMPH-02910 | Somatostatin Protein, Mouse, Recombinant (His & KSI) | Mouse | E. coli |
Somatostatin Protein, Mouse, Recombinant (His & KSI) is expressed in E. coli expression system with N-6xHis-KSI tag. The predicted molecular weight is 18.5 kDa and the accession number is P60041. | |||
TMPK-01293 | SOST Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
SOST, also known as sclerostin, is a member of the cerberus/DAN family, a group of secreted glycoproteins characterized by a cysteine-knot motif. SOST is negative regulator of bone growth that acts through inhibition of ... | |||
TMPH-00323 | Snaclec rhodocytin subunit beta Protein, Calloselasma rhodostoma, Recombinant (His & Myc) | Calloselasma rhodostoma | E. coli |
Elicits platelet aggregation by the binding to the C-type lectin domain family 1 member B (CLEC1B/CLEC2). Binding leads to tyrosine phosphorylation in the cytoplasmic tail of CLEC1B, which promotes the binding of spleen ... | |||
TMPY-02230 | Influenza A H5N2 (A/ostrich/South Africa/AI1091/2006) Hemagglutinin/HA1 Protein (His) | H5N2 | HEK293 Cells |
Influenza A H5N2 (A/ostrich/South Africa/AI1091/2006) Hemagglutinin/HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.2 kDa and the accession number is B0F0B2. | |||
TMPH-00404 | Acetoacetate decarboxylase Protein, Clostridium acetobutylicum, Recombinant (His) | Clostridium acetobutylicum | Baculovirus Insect Cells |
Catalyzes the conversion of acetoacetate to acetone and carbon dioxide. Acetoacetate decarboxylase Protein, Clostridium acetobutylicum, Recombinant (His) is expressed in Baculovirus insect cells with C-6xHis tag. The pre... | |||
TMPH-00420 | Perfringolysin O Protein, Clostridium perfringens, Recombinant (His & SUMO) | C.perfringens | E. coli |
Perfringolysin O Protein, Clostridium perfringens, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 68.7 kDa and the accession number is P0C2E9. | |||
TMPH-00476 | DNA-PKcs Protein, Dictyostelium discoideum, Recombinant (His & Myc) | Dictyostelium discoideum | E. coli |
DNA-PKcs Protein, Dictyostelium discoideum, Recombinant (His & Myc) is expressed in E. coli. | |||
TMPH-03346 | Osteocalcin Protein, Rat, Recombinant (GST) | Rat | E. coli |
Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium. Osteocalcin Protein, Rat, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight i... | |||
TMPH-02415 | Lysyl endopeptidase Protein, Lysobacter enzymogenes, Recombinant (His & SUMOstar) | Lysobacter enzymogenes | P. pastoris (Yeast) |
Highly specific endopeptidase that hydrolyzes lysyl bonds including the Lys-Pro bond. Lysyl endopeptidase Protein, Lysobacter enzymogenes, Recombinant (His & SUMOstar) is expressed in yeast with N-6xHis-SUMOSTAR tag. The... | |||
TMPH-00418 | Rubredoxin Protein, Clostridium pasteurianum, Recombinant (His & SUMO) | Clostridium pasteurianum | E. coli |
Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule. Rubredoxin Protein, Cl... | |||
TMPH-00423 | Tetanus toxin Protein, Clostridium tetani, Recombinant (B2M & His) | Clostridium tetani | E. coli |
Tetanus toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynapt... | |||
TMPH-00380 | Osteocalcin Protein, Chicken, Recombinant (His & KSI) | Chicken | E. coli |
Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium. Osteocalcin Protein, Chicken, Recombinant (His & KSI) is expressed in E. coli expression system with N-6xHis-KSI tag. The predicted mo... | |||
------------------------ More ------------------------ |
Cat No. | Product Name | ||
---|---|---|---|
L7900 | Osteogenesis Compound Library | 317 compounds | |
A unique collection of 317 osteogenesis related compounds for high throughput and high content screening; | |||
L2195 | Anti-Prostate Cancer Compound Library | 2070 compounds | |
2070 compounds associated with prostate cancer that can be used for high-throughput and high-content screening. |