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Thiostrepton

Catalog No. T1679   CAS 1393-48-2
Synonyms: Thiactin, Bryamycin, Alaninamide

Thiostrepton (Alaninamide) is a one of the CYCLIC PEPTIDES from Streptomyces that is active against gram-positive bacteria. In veterinary medicine, it has been used in mastitis caused by gram-negative organisms and in dermatologic disorders.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
Thiostrepton Chemical Structure
Thiostrepton, CAS 1393-48-2
Pack Size Availability Price/USD Quantity
25 mg In stock $ 30.00
50 mg In stock $ 39.00
100 mg In stock $ 55.00
1 mL * 10 mM (in DMSO) In stock $ 47.00
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Purity: 99.57%
Purity: 99.33%
Purity: 99%
Purity: 98.95%
Purity: 98.73%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Thiostrepton (Alaninamide) is a one of the CYCLIC PEPTIDES from Streptomyces that is active against gram-positive bacteria. In veterinary medicine, it has been used in mastitis caused by gram-negative organisms and in dermatologic disorders.
Synonyms Thiactin, Bryamycin, Alaninamide
Molecular Weight 1664.89
Formula C72H85N19O18S5
CAS No. 1393-48-2

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 40 mg/mL

TargetMolReferences and Literature

1. Kuiper EG, Conn GL. J Biol Chem. 2014 Sep 19;289(38):26189-200. 2. Lai W, Zhu W, Li X, et al. GTSE1 promotes prostate cancer cell proliferation via the SP1/FOXM1 signaling pathway[J]. Laboratory Investigation . 2020: 1-10. 3. Zhou Z, Chen H, Xie R, et al. Epigenetically modulated FOXM 1 suppresses dendritic cell maturation in pancreatic cancer and colon cancer[J]. Molecular oncology. 2019 Apr;13(4):873-893.

TargetMolCitations

1. Zhou Z, Chen H, Xie R, et al. Epigenetically modulated FOXM 1 suppresses dendritic cell maturation in pancreatic cancer and colon cancer. Molecular Oncology. 2019, 13(4): 873-893 2. Lai W, Zhu W, Li X, et al. GTSE1 promotes prostate cancer cell proliferation via the SP1/FOXM1 signaling pathway. Laboratory Investigation. 2021 May;101(5):554-563.

Related compound libraries

This product is contained In the following compound libraries:
Microbial Natural Product Library Macrocyclic Compound Library Cell Cycle Compound Library Anti-Bacterial Compound Library Cyclic Peptide Library NO PAINS Compound Library Antibiotics Library Anti-Infection Compound Library Peptide Compound Library Inhibitor Library

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Thiostrepton 1393-48-2 Cell Cycle/Checkpoint DNA Damage/DNA Repair Microbiology/Virology Antibacterial DNA/RNA Synthesis Antibiotic inhibit Bacterial Thiactin Bryamycin Inhibitor Alaninamide inhibitor

 

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