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LANOSTEROL

Catalog No. T4970 CAS 79-63-0

Synonyms: 3β-Hydroxy-8,24-lanostadiene, 8,24-Lanostadien-3β-ol

Lanosterol (3β-Hydroxy-8,24-lanostadiene) is a tetracyclic triterpenoid which is the compound from which all steroids are derived.

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LANOSTEROL, CAS 79-63-0

Pack Size	Availability	Price/USD
1 mg	In stock	$ 53.00
50 mg	In stock	$ 434.00
100 mg	In stock	$ 642.00

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Purity: 99.67%

Purity: 99.42%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Lanosterol (3β-Hydroxy-8,24-lanostadiene) is a tetracyclic triterpenoid which is the compound from which all steroids are derived.

Synonyms	3β-Hydroxy-8,24-lanostadiene, 8,24-Lanostadien-3β-ol
Molecular Weight	426.72
Formula	C30H50O
CAS No.	79-63-0

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

Ethanol: 10 mM, Sonication is recommended.

DMSO: Insoluble

References and Literature

1. Sinha R , Ahn J , Sampson J N , et al. Fecal Microbiota, Fecal Metabolome, and Colorectal Cancer Interrelations[J]. PLOS ONE, 2016, 11(3):e0152126. 2. Goedert J J, Sampson J N, Moore S C, et al. Fecal metabolomics: assay performance and association with colorectal cancer[J]. Carcinogenesis, 2014, 35(9):2089.

Citations

1. Liu Y, Wang Z, Jin H, et al.Squalene-epoxidase-catalyzed 24 (S), 25-epoxycholesterol synthesis promotes trained-immunity-mediated antitumor activity.Cell Reports.2024, 43(4).

Related compound libraries

This product is contained In the following compound libraries：

Tobacco Monomer Library Human Endogenous Metabolite Library Natural Product Library Bioactive Lipid Compound Library Inactive Ingredient Library Selected Plant-Sourced Compound Library Anti-COVID-19 Traditional Chinese Medicine Compound Library Traditional Chinese Medicine Monomer Library NO PAINS Compound Library Food as Medicine Compound Library

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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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Molecular Weight Calculator

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Mass of a compound required to prepare a solution of known volume and concentration
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An example of a molarity calculation using the molarity calculator
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
Enter 197.13 into the Molecular Weight (MW) box
Enter 10 into the Concentration box and select the correct unit (millimolar)
Enter 10 into the Volume box and select the correct unit (milliliter)
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The answer of 19.713 mg appears in the Mass box

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Calculator the dilution required to prepare a stock solution

Calculate the dilution required to prepare a stock solution
The dilution calculator is a useful tool which allows you to calculate how to dilute a stock solution of known concentration. Enter C1, C2 & V2 to calculate V1.

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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
Enter 10 into the Concentration (start) box and select the correct unit (millimolar)
Enter 50 into the Concentration (final) box and select the correct unit (micromolar)
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The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

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Molecule Formula

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Instructions to calculate molar mass (molecular weight) of a chemical compound:
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Definitions of molecular mass, molecular weight, molar mass and molar weight:
Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed n the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

LANOSTEROL 79-63-0 Metabolism Endogenous Metabolite cholesterol degradation Inhibitor inhibit misfolded intermediate synthesis 8,24-Lanostadien-3b-ol 8,24-Lanostadien-3beta-ol 3beta-Hydroxy-8,24-lanostadiene cytotoxicity 3b-Hydroxy-8,24-lanostadiene 3β-Hydroxy-8,24-lanostadiene 8,24-Lanostadien-3β-ol ubiquitination inhibitor

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