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Prostaglandin G/H synthase 1 inhibitor

Catalog No. T27066 CAS 4943-86-6

Synonyms: CP74006, CP 74006, 2-Amino-N-(4-chlorophenyl)benzamide

Prostaglandin G/H synthase 1 inhibitor (CP 74006) is a selective D5D inhibitor with an IC(50) value of 20 nM.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Prostaglandin G/H synthase 1 inhibitor Chemical Structure

Prostaglandin G/H synthase 1 inhibitor, CAS 4943-86-6

Pack Size	Availability	Price/USD
50 mg	In stock	$ 40.00
100 mg	In stock	$ 64.00
200 mg	In stock	$ 93.00
500 mg	In stock	$ 155.00
1 g	In stock	$ 228.00
1 mL * 10 mM (in DMSO)	In stock	$ 39.00

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Purity: 98.5%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Prostaglandin G/H synthase 1 inhibitor (CP 74006) is a selective D5D inhibitor with an IC(50) value of 20 nM.
In vitro	Prostaglandin G/H synthase 1 inhibitor inhibits D5D in the rat liver microsomal assay with IC50 of 0.04 μM[2].

Synonyms	CP74006, CP 74006, 2-Amino-N-(4-chlorophenyl)benzamide
Molecular Weight	246.69
Formula	C13H11ClN2O
CAS No.	4943-86-6

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 50 mg/mL (202.68 mM)

References and Literature

1. Zhang L, et al. A multiplexed cell assay in HepG2 cells for the identification of delta-5, delta-6, and delta-9 desaturase and elongase inhibitors. J Biomol Screen. 2010 Feb;15(2):169-76. 2. Obukowicz MG, Welsch DJ, Salsgiver WJ, Martin-Berger CL, Chinn KS, Duffin KL, Raz A, Needleman P. Novel, selective delta6 or delta5 fatty acid desaturase inhibitors as antiinflammatory agents in mice. J Pharmacol Exp Ther. 1998 Oct;287(1):157-66.

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Prostaglandin G/H synthase 1 inhibitor 4943-86-6 Others CP74006 CP 74006 CP-74006 2-Amino-N-(4-chlorophenyl)benzamide inhibitor inhibit

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