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Search Results for " caspase-1 "

148

Compounds

36

Natural Products

1751

Recombinant Proteins

1

Libraries

Cat No. Product Name Synonyms Targets
T70650 Caspase-6-IN-1
Caspase-6-IN-1 is a novel Allosteric Inhibitor of Caspase-6 Activation, blocking the interaction between C6 and mHTT1-586.
TP1466 Z-YVAD-FMK Caspase
AA-Z-YVAD-FMK is a Irreversible caspase-1 inhibitor,with anti-inflammatory and anti-tumor activities.
T10384 Farudodstat ASLAN003 Apoptosis , Dehydrogenase , DNA/RNA Synthesis
Farudodstat (ASLAN003) is an orally active and potent inhibitor of DHODH (Human Dihydroorotate Dehydrogenase) with antitumor activity. It has the potential to be a first-in-class candidate in AML.
T36347 Ac-YVAD-CMK Caspase-1 Inhibitor II,Ac-Tyr-Val-Ala-Asp-chloromethylketone,Ac-Tyr-Val-Ala-Asp-CMK IL Receptor , Caspase , Immunology/Inflammation related , Pyroptosis
Ac-YVAD-CMK (Ac-Tyr-Val-Ala-Asp-CMK) is a selective and irreversible inhibitor of Caspase-1 and inhibits pyroptosis, IL-1β and IL-18. Ac-YVAD-CMK shows neuroprotective and anti-inflammatory capacity.
T5104 BTSA1 Apoptosis , BCL
BTSA1 is a BAX activator that binds with high affinity and specificity to the N-terminal activation site and induces conformational changes to BAX leading to BAX-mediated apoptosis.
T2503 PAC-1 Procaspase activating compound 1 Apoptosis , Caspase , Autophagy
PAC-1 (Procaspase activating compound 1) has been used in trials studying the treatment of Lymphoma, Melanoma, Solid Tumors, Breast Cancer, and Thoracic Cancers, among others.
T9118 KEA1-97 Apoptosis , Others , Caspase
Kea1-97 is a selective disruptor of interaction between thioredoxin and caspase-3 (IC50 = 10 μ M). Kea1-97 destroys the interaction between thioredoxin and caspase 3 and activates caspases without affecting the activity ...
T3103 L67 DNA Ligase Inhibitor DNA , DNA/RNA Synthesis
L67 (DNA Ligase Inhibitor) is a competitive human DNA ligase inhibitor, inhibits DNA ligases I and III (IC50: 10 μM).
T22119 NS3694 Apoptosis
NS3694 is an inhibitor of apoptosis and inhibits apoptosome formation and caspase activation.
T0432 Diclofenac diethylamine Apoptosis , COX
Diclofenac Diethylamine, a non-selective COX inhibitor, is utilized as a nonsteroidal anti-inflammatory drug (NSAID).
T63479 Caspase-3-IN-1
Caspase-3-IN-1 is a potent inhibitor of Caspase-3 (IC50: 14.5 nM).
T76571 Caspase-8-IN-1
Caspase-8-IN-1 is a potent caspase-8 inhibitor [1] .
T79743 Caspase-3 activator 1 Pyroptosis
Caspase-3 activator 1 (compound 4b), a Ru(III) metal complex, effectively inhibits gastric tumor growth and metastasis by mediating caspase-3 cleavage. This cleavage enables Caspase-3 to process gasdermin E (GSDME), whic...
T12412L PDK4-IN-1 hydrochloride Apoptosis , PDK
PDK4-IN-1 hydrochloride is an anthraquinone derivative and a potent and orally active inhibitor of pyruvate dehydrogenase kinase 4 (PDK4)(IC50 value of 84 nM)
T8478 SC-43 Apoptosis , Phosphatase , STAT
SC-43 is a potent and orally active agonist of SHP-1 (PTPN6). SC-43 inhibits the phosphorylation of STAT3 and induces cell apoptosis, and with anti-fibrotic and anticancer effects.
T28178 NLRP3-IN-9 INF-4E,INF 4E,INF4E NOD
NLRP3-IN-9 (INF-4E) is an inhibitor of NLRP3 ATPase and caspase-1. NLRP3-IN-9 acts by irreversibly trapping thiol nucleophiles, which prevents both ATP- and nigericin-triggered pyroptosis of human THP-1 cells in a time- ...
T0196 Diclofenac Diclofenacum,Voltaren Apoptosis , COX
Diclofenac (Diclofenacum) is a nonsteroidal benzeneacetic acid derivative with anti-inflammatory activity. Diclofenac binds and chelates both isoforms of cyclooxygenase (COX-1 and-2), thereby blocking the conversion of a...
T6085 PF-543 Sphingosine Kinase 1 Inhibitor II,PF 543 Apoptosis , S1P Receptor , Autophagy , LPL Receptor
PF-543 (Sphingosine Kinase 1 Inhibitor II), a novel sphingosine-competitive inhibitor of SphK1, inhibits SphK1 with IC50 and Ki of 2.0 nM and 3.6 nM.
T15418 GS-6201 CVT-6883 Adenosine Receptor
GS-6201 (CVT-6883) is a selective antagonist of adenosine A2B receptor. GS-6201 shows high affinity and selectivity for the human adenosine A2B receptors with a Ki of 22 nM.
T1555 Diclofenac sodium GP 45840 Apoptosis , COX
Diclofenac sodium (GP 45840) is a non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.
T6470 Diclofenac Potassium CGP-45840B,Cataflam,Voltfast Apoptosis , Others , COX
Diclofenac Potassium (CGP-45840B) is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions.
T9083 TC11 CLT-003,1H-Isoindole-1,3(2H)-dione, 5-amino-2-[2,6-bis(1-methylethyl)phenyl]-TC11 BCL , Caspase , CDK
TC11 (1H-Isoindole-1,3(2H)-dione, 5-amino-2-[2,6-bis(1-methylethyl)phenyl]-TC11) is a potent inhibitor of tumor cell proliferation and an inducer of apoptosis via activation of caspase-3, 8 and 9.
T23861 CAY10526 CAY-10526,BTH,CAY 10526 Prostaglandin Receptor
CAY10526 (BTH) is a selective mPGES-1 inhibitor that acts as an inhibitor of the NF-κB signaling pathway.
T2613 Almorexant ACT 078573 OX Receptor
Almorexant (ACT 078573) is a potent and competitive dual orexin 1 receptor (OX1)/orexin 2 receptor (OX2) antagonist with Ki values of 1.3 and 0.17 nM for OX1 and OX2, respectively.
T8840 PF-543 hydrochloride PF-543 Apoptosis , S1P Receptor , Autophagy , LPL Receptor
PF-543 hydrochloride (PF-543) inhibits SphK1 with a K(i) of 3.6 nM, is sphingosine-competitive and is more than 100-fold selective for SphK1 over the SphK2 isoform.
T6155 Almorexant hydrochloride ACT-078573 hydrochloride,Almorexant HCl OX Receptor
Almorexant hydrochloride (ACT-078573 hydrochloride) is a potent and competitive dual orexin 1 receptor (OX1)/orexin 2 receptor (OX2) antagonist with Ki values of 1.3 and 0.17 nM for OX1 and OX2, respectively.
T73556 CZL55 Caspase
CZL55 is a potent caspase-1 inhibitor with an IC50 value of 0.024 μM.CZL55 has low cytotoxicity and can be used in the study of febrile seizures (FS).
T6090 Belnacasan VX-765 Caspase
Belnacasan (VX-765) is an orally active IL-converting enzyme/caspase-1 inhibitor.
T36819 Ac-FLTD-CMK Caspase
Ac-FLTD-CMK is an inhibitor derived from abscisicin D (GSDMDD) with specific inhibitory effects on inflammatory caspases. ac-FLTD-CMK showed inhibitory effects on caspases-1, caspases-4 and caspases-11 with IC50s of 46.7...
T10366L Arg-Gly-Asp-Ser acetate Arg-Gly-Asp-Ser acetate(91037-65-9 free base) Integrin
Arg-Gly-Asp-Ser acetate is an integrin binding sequence that directly and specifically bind pro-caspase-8, pro-caspase-9 and pro-caspase-3, while it does not bind pro-caspase-1. Arg-Gly-Asp-Ser acetate inhibits integrin ...
T7016 VR23 Apoptosis , Proteasome , Caspase
VR23 is a potent proteasome inhibitor. Data shows IC50 =1 nM for trypsin-like proteasomes, IC50=50-100 nM for chymotrypsin-like proteasomes, and IC50=3 μM for caspase-like proteasomes.
T8468 CIL62 Caspase
CIL62 is a caspase-3/7-independent inducer of cell death. The mechanism of action of CIL62 is Necrostatin-1 dependent cell death [1].
T26193 SKLB-163 SKLB163 MAPK , Akt , Caspase , Rho , JNK
SKLB-163 acts by downregulating RhoGDI, activating JNK-1 signaling pathway and caspase-3, and reducing phosphorylated Akt and p44/42 MAPK.
T78631 Ac-YVAD-AOM Caspase
Ac-YVAD-AOM is a selective and potent caspase-1 inhibitor showing antitumor activity and potential analgesic activity.
T77579 JC2-11 IL Receptor , Dehydrogenase , ROS , Caspase , NOD-like Receptor (NLR) , AIM2
JC2-11 is an inhibitory compound for inflammation.JC2-11 inhibits the recruitment domain-containing proteins NLRC 4, atypical in melanoma 2 (AIM 2) and atypical (NC) inflammatory vesicles by disrupting reactive oxygen sp...
T1772 MDK83190 Apoptosis Activator 2 Apoptosis , Caspase
MDK83190 (Apoptosis Activator 2) is a potent apoptosis activator, induceing caspase-3 activation, PARP cleavage, and DNA fragmentation .
T26326 VU0285655-1 VU-0285655,VU0285655,BML 280,VU 0285655,BML280,BML-280 TNF , Phospholipase , Interleukin
VU0285655-1(BML-280) is a potent and selective phospholipase D2 (PLD2) inhibitor that inhibits the proliferation of PLD2-deficient cells.VU0285655-1 has an inhibitory effect on high glucose-induced caspase-3 cleavage and...
T16680 PTC-028 Apoptosis , BMI-1
PTC-028 selectively suppresses cancer cells whereas normal cells remain unaffected. PTC-028 is an orally bioavailable inhibitor of stem cell factor BMI-1 in ovarian cancer. The depletion of BMI-1 by PTC-028 causes caspas...
T10896L CSRM617 hydrochloride CSRM617 hydrochloride(787504-88-5 Free base) Apoptosis , Others , Androgen Receptor
CSRM617 hydrochloride is a selective small-molecule inhibitor of the transcription factor ONECUT2 ( OC2, a master regulator of androgen receptor) with a K d of 7.43 uM in SPR assays, directly binds to OC2-HOX domain. CSR...
T11766L Eltanexor ONO-7706,KPT-8602,ATG-016 Others
Eltanexor (ONO-7706) is an orally active exportin-1 (XPO1) inhibitor. It has effective anti-leukemic activity. Eltanexor inhibits XPO1-dependent nuclear export (EC50=60.9 nM) by directly targeting XPO1. Eltanexor causes ...
T76787 Conatumumab TRAIL-R2 mAb,AMG 655 TNF
Conatumumab (AMG 655) is a monoclonal agonist antibody targeting human death receptor 5 (DR5, TRAILR2) at Kd 1 nM for long DR5 and Kd 0.8 nM for short DR5. Conatumumab induces apoptosis in a variety of tumor types throug...
T3701 MCC950 CP-456773 NOD
CP-456773 (MCC950 (CP-456773) and CRID3) is an effective and specific cytokine release inhibitor and NLRP3 inflammasome inhibitor. CP-456773 inhibits IL-1β secretion and caspase 1 processing. MCC950 blocked canonical and...
T63321 20S Proteasome activator 1 Proteasome
20S Proteasome activator 1 is a 20S proteasome activator with IC50 of 0.3 μM for trypsin-like sites, 0.7 μM for chymotrypsin-like sites and 1.8 μM for caspase sites. 20S Proteasome activator 1 prevents the accumulation o...
T2085 PQ401 IGF-1R Inhibitor II Apoptosis , IGF-1R
PQ401 (IGF-1R Inhibitor II) suppresses autophosphorylation of IGF-1R domain(IC50<1 μM).
TQ0146 Ac-DEVD-CHO Apoptosis , Caspase
Ac-DEVD-CHO is a specific Caspase-3 inhibitor (Ki: 230 pM).Ac-DEVD-CHO has an inhibitory effect in SLNT-induced apoptosis.
T6761 Ossirene AS101 IL Receptor , Caspase , Interleukin
Ossirene (AS101), a potent in vitro and in vivo immunomodulator, is a novel inhibitor of IL-1beta converting enzyme.
T0282 Q-VD-OPH Quinoline-Val-Asp-Difluorophenoxymethylketone Caspase , HIV Protease
Q-VD-OPH (Quinoline-Val-Asp-Difluorophenoxymethylketone) is a pan-caspase inhibitor with potent antiapoptotic properties.
T16105 ML132 NCGC 00185682 Others
ML132 is an effective and selective inhibitor of caspase 1 (IC50: 0.316 nM).
T80093 IETD-CHO TFA Caspase
IETD-CHO TFA (Caspase-8-IN-1) functions as a potent inhibitor of caspase-8 [1].
T76665 Z-LEED-FMK
Z-LEED-FMK is a chemical compound that acts as an inhibitor for caspase-13 and caspase-4. Additionally, it impedes caspase-1 processing in S. typhimurium-infected macrophages [1] [2].

Compounds

Caspase-6-IN-1
T70650
Synonym:
Target:
Z-YVAD-FMK
TP1466
Synonym:
Target: Caspase
Farudodstat
T10384
Synonym: ASLAN003
Target: Apoptosis, Dehydrogenase, DNA/RNA Synthesis
Ac-YVAD-CMK
T36347
Synonym: Caspase-1 Inhibitor II,Ac-Tyr-Val-Ala-Asp-chloromethylketone,Ac-Tyr-Val-Ala-Asp-CMK
Target: IL Receptor, Caspase, Immunology/Inflammation related, Pyroptosis
BTSA1
T5104
Synonym:
Target: Apoptosis, BCL
PAC-1
T2503
Synonym: Procaspase activating compound 1
Target: Apoptosis, Caspase, Autophagy
KEA1-97
T9118
Synonym:
Target: Apoptosis, Others, Caspase
L67
T3103
Synonym: DNA Ligase Inhibitor
Target: DNA, DNA/RNA Synthesis
NS3694
T22119
Synonym:
Target: Apoptosis
Diclofenac diethylamine
T0432
Synonym:
Target: Apoptosis, COX
Caspase-3-IN-1
T63479
Synonym:
Target:
Caspase-8-IN-1
T76571
Synonym:
Target:
Caspase-3 activator 1
T79743
Synonym:
Target: Pyroptosis
PDK4-IN-1 hydrochloride
T12412L
Synonym:
Target: Apoptosis, PDK
SC-43
T8478
Synonym:
Target: Apoptosis, Phosphatase, STAT
NLRP3-IN-9
T28178
Synonym: INF-4E,INF 4E,INF4E
Target: NOD
Diclofenac
T0196
Synonym: Diclofenacum,Voltaren
Target: Apoptosis, COX
PF-543
T6085
Synonym: Sphingosine Kinase 1 Inhibitor II,PF 543
Target: Apoptosis, S1P Receptor, Autophagy, LPL Receptor
GS-6201
T15418
Synonym: CVT-6883
Target: Adenosine Receptor
Diclofenac sodium
T1555
Synonym: GP 45840
Target: Apoptosis, COX
Diclofenac Potassium
T6470
Synonym: CGP-45840B,Cataflam,Voltfast
Target: Apoptosis, Others, COX
TC11
T9083
Synonym: CLT-003,1H-Isoindole-1,3(2H)-dione, 5-amino-2-[2,6-bis(1-methylethyl)phenyl]-TC11
Target: BCL, Caspase, CDK
CAY10526
T23861
Synonym: CAY-10526,BTH,CAY 10526
Target: Prostaglandin Receptor
Almorexant
T2613
Synonym: ACT 078573
Target: OX Receptor
PF-543 hydrochloride
T8840
Synonym: PF-543
Target: Apoptosis, S1P Receptor, Autophagy, LPL Receptor
Almorexant hydrochloride
T6155
Synonym: ACT-078573 hydrochloride,Almorexant HCl
Target: OX Receptor
CZL55
T73556
Synonym:
Target: Caspase
Belnacasan
T6090
Synonym: VX-765
Target: Caspase
Ac-FLTD-CMK
T36819
Synonym:
Target: Caspase
Arg-Gly-Asp-Ser acetate
T10366L
Synonym: Arg-Gly-Asp-Ser acetate(91037-65-9 free base)
Target: Integrin
VR23
T7016
Synonym:
Target: Apoptosis, Proteasome, Caspase
CIL62
T8468
Synonym:
Target: Caspase
SKLB-163
T26193
Synonym: SKLB163
Target: MAPK, Akt, Caspase, Rho, JNK
Ac-YVAD-AOM
T78631
Synonym:
Target: Caspase
JC2-11
T77579
Synonym:
Target: IL Receptor, Dehydrogenase, ROS, Caspase, NOD-like Receptor (NLR), AIM2
MDK83190
T1772
Synonym: Apoptosis Activator 2
Target: Apoptosis, Caspase
VU0285655-1
T26326
Synonym: VU-0285655,VU0285655,BML 280,VU 0285655,BML280,BML-280
Target: TNF, Phospholipase, Interleukin
PTC-028
T16680
Synonym:
Target: Apoptosis, BMI-1
CSRM617 hydrochloride
T10896L
Synonym: CSRM617 hydrochloride(787504-88-5 Free base)
Target: Apoptosis, Others, Androgen Receptor
Eltanexor
T11766L
Synonym: ONO-7706,KPT-8602,ATG-016
Target: Others
Conatumumab
T76787
Synonym: TRAIL-R2 mAb,AMG 655
Target: TNF
MCC950
T3701
Synonym: CP-456773
Target: NOD
20S Proteasome activator 1
T63321
Synonym:
Target: Proteasome
PQ401
T2085
Synonym: IGF-1R Inhibitor II
Target: Apoptosis, IGF-1R
Ac-DEVD-CHO
TQ0146
Synonym:
Target: Apoptosis, Caspase
Ossirene
T6761
Synonym: AS101
Target: IL Receptor, Caspase, Interleukin
Q-VD-OPH
T0282
Synonym: Quinoline-Val-Asp-Difluorophenoxymethylketone
Target: Caspase, HIV Protease
ML132
T16105
Synonym: NCGC 00185682
Target: Others
IETD-CHO TFA
T80093
Synonym:
Target: Caspase
Z-LEED-FMK
T76665
Synonym:
Target:
1 2 3
Cat No. Product Name Synonyms Targets
T2764 (S)-10-Hydroxycamptothecin 10-Hydroxycamptothecin,10-HCPT Apoptosis , Topoisomerase
(S)-10-Hydroxycamptothecin (10-HCPT) is a DNA topoisomerase I inhibitor, utilized as a clinical therapy agent against hepatoma.
T2851 Daphnetin 7,8-Dihydroxycoumarin,Daphnetol EGFR , PKA , PKC , Parasite , Autophagy
Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM), and PKC (IC50: 25.01 μM), also exhibit anti-oxidant and anti-...
T4085 Paris saponin VII Chonglou Saponin VII,Polyphyllin-VII,Dioscinin,Paris saponin-VII Apoptosis , BCL , Others , PARP , p38 MAPK , Akt , Caspase , P-gp , Autophagy
Paris saponin VII (Dioscini) shows inhibitory effects on cell proliferation.
T3892 Isoacteoside Isoverbascoside NF-κB
Isoacteoside has the anti-inflammatory effect, mediated by action on caspase-1, mitogen-activated protein kinases (c-Jun N-terminal kinase, p38, extracellular signal-regulated protein kinase) and nuclear factor-kappa B p...
TN1880 Lucidenic acid B Lucidenicacid B Apoptosis , Caspase
Lucidenic acid B (Lucidenicacid B), a natural compound extracted from Ganoderma lucidum, induces activation of caspase-9 and caspase-3 and cleavage of PARP, which can induce apoptosis in human leukemia cells through mito...
T5S2283 Sesamolin p38 MAPK , Caspase , JNK
1. Sesamolin and Sesamin has neuroprotective effect. 2. Sesamolin protects microglia against H2O2-induced cell injury, by inhibiting of p38 MAPK and caspase-3 activation and ROS production. 3. Sesamolin and Sesamin can s...
T3S0335 Soyasaponin Bb Soyasaponin I NF-κB , Caspase
1. Soyasaponin Bb (Soyasaponin I) can suppress Eca-976 cell growth, reverse effects on over expression of c-met, VEGF, and induce cell apoptosis through inhibiting HDAC1-NF-kappaB and activating PETEN and caspase-3 signa...
T4S1335 Daphnoretin Dephnoretin,Thymelol Influenza Virus , Caspase , PKC
1. Daphnoretin (Thymelol) has strong antiviral activity, mainly on the later phase of the replication cycle. 2. Daphnoretin has anticancer effects on leukemia, osteosarcoma and uterine cervix cancer cells, might through ...
T16791 Rottlerin Mallotoxin,NSC 56346,NSC 94525 CaMK , Apoptosis , Others , HIV Protease , PKA , PKC , Autophagy
Rottlerin (NSC-56346) is a natural product purified from Mallotus Philippinensis and is a specific PKC inhibitor (IC50: PKCδ of 3-6 μM, PKCα,β,γ of 30-42 μM, PKCε,η,ζ of 80-100 μM). Rottlerin causes apoptosis via caspase...
T6S1597 Mulberroside A TNF , Tyrosinase , Interleukin
1. Mulberroside has nephroprotective, hypoglycemic, and antidiabetic effects. 2. Mulberroside A is a glycosylated stilbene of oxyresveratrol; thus, the deglycosylation of Mulberroside A resulted in enhanced inhibition of...
T3S1227 Aristolactam I Aristolactam,Aristololactam I,Aristololactum Apoptosis , Caspase
1.Aristolactam I (Aristololactum) has cytotoxic potency, mediated through the induction of apoptosis in a caspase 3-dependent pathway. 2. The effects of Aristololactam I may be mediated by different mechanisms except TGF...
T2S2362 Dehydrocorydaline nitrate BCL , Others , PARP , p38 MAPK , Caspase , Parasite , Autophagy
1. Dehydrocorydaline(DHC) not only inhibits antibody-mediated allergic reactions but also influences cell-mediated allergic reactions, and the inhibitory effect of Corydalis Tuber on allergic reactions may be partially a...
T6S2315 Polyphyllin VI Apoptosis , Antibacterial , Pyroptosis
1. Polyphyllin VI has hemostasis , expectorant , bacteriostasis, anticytotoxic, anti pregnancy kill sperm effects.
T2768 Saikosaponin A NF-κB , Antibacterial , Liver X Receptor
Saikosaponin A has a variety of pharmacological benefits, including antiepileptic, anti-osteoporosis, antioxidant, anti-in ammatory, immunomodulatory, and anti-bacterial activities. It can effectively attenuate neuropath...
T2909 Fraxetin 7,8-dihydroxy-6-methoxy coumarin Apoptosis , Others
Fraxetin (7,8-dihydroxy-6-methoxy coumarin) has dual-antioxidative ,hepatoprotective and antihyperglycemic functions, it shows potent protective effects against CCl4 induced oxidative stress and hepatic fibrosis, has a m...
T5S1805 5,7-Dihydroxychromone 5,7-Dihydroxy-4H-Chromen-4-One Others , Virus Protease , PARP , Caspase , Nrf2
1. 5,7-Dihydroxychromone (5,7-Dihydroxy-4H-Chromen-4-One) isolated from DME is one of the active compounds that may contribute to regulate blood glucose levels. 2. 5,7-Dihydroxychromone exerts neuroprotective effect agai...
T5S2358 Dehydrocorydaline Dehydrocorydalin,13-Methylpalmatine BCL , PARP , p38 MAPK , Caspase , Parasite , Autophagy
1. Dehydrocorydaline (13-Methylpalmatine) exerts anti-metastatic potential via suppression of MMPs and Bcl-2 signaling in NSC-LC cells. 2. Dehydrocorydaline stimulates p38 MAPK activation, which can enhance heterodimeriz...
T3S2344 β,β-Dimethylacrylshikonin Dimethylacrylshikonin,β, β-Dimethylacrylshikonin ERK , HIF/HIF Prolyl-Hydroxylase
1. β,β-Dimethylacrylshikonin (Dimethylacrylshikonin) is a promising agent for developing an improved strategy for radiotherapy against tumors. (a) Injection of Dimethylacrylshikonin combined with IR treatment significant...
T6S0721 Orientin Lutexin,Luteolin-8-glucoside Others
1. Orientin (Luteolin-8-glucoside) may be regarded as a candidate therapeutic agent for treatment of vascular inflammatory diseases via inhibition of the HMGB1 signaling pathway. 2. Orientin protects vascular barrier int...
T5S1632 Barlerin 8-O-Acetylshanzhiside methyl ester,ND01 VEGFR , TNF , NF-κB , Akt , Caspase
Barlerin (8-O-Acetylshanzhiside methyl ester) has potential against cerebral ischemic injury, and its protective effect on oxygen-glucose deprivation-induced injury might be due to the suppression of intracellular Ca2+ e...
T4S0498 Glaucocalyxin A Wangzaozin B,Leukamenin F Apoptosis , Akt , Caspase , PI3K
1. Glaucocalyxin A (Leukamenin F)-SBE-β-CD could be useful with a better solubility and sustained function in drug delivery. 2. Glaucocalyxin A activates caspase-3, decreases BAD phosphorylation, and reduces the expressi...
T4S2126 Ginkgetin Apoptosis , Wnt/beta-catenin , COX , STAT , Autophagy
1. Ginkgetin has anti-influenza virus and anti-fungal activities. 2. Ginkgetin has anti-inflammatory activity, can down-regulates COX-2 induction in vivo against skin inflammatory responses. 3. Ginkgetin is a good STAT3 ...
T4S2326 Cornuside 7-Galloylsecologanol,7-O-Galloylsecologanol,Comuside ERK , p38 MAPK , NF-κB , JNK
1. Cornuside (Comuside) has immunomodulatory activity . 2. Cornuside suppresses expression levels of cytokine-induced proinflammatory and adhesion molecules in the human endothelial cells. 3. Cornuside can treat myocardi...
T5558 Chelidonic acid Jervaic acid,Jerva acid,γ-Pyrone-2,6-dicarboxylic acid NF-κB , Caspase
Chelidonic acid (Jervaic acid) is a component of Chelidonium majus L., used as a mild analgesic, an antimicrobial, an acentral nervous system sedative. Chelidonic acid (Jervaic acid) also shows anti-inflammatory activity...
T5S0661 Koumine Others
1. Koumine can treat the diabetic neuropathy. 2. Koumine has antineoplastic effect, may be a future breast cancer chemotherapeutic agent. 3. Koumine has a significant analgesic effect in rodent behavioral models of infla...
T5S0055 Chelidonine Helidonine,Khelidonin,Stylophorin Apoptosis , Others , Influenza Virus
1. Chelidonine (Stylophorin) isolated from Chelidonium majus efficiently induced apoptosis in HeLa cells through possible alteration of p38-p53 and AKT/PI3 kinase signalling pathways. 2. Chelidonine is a promising model ...
T14003 15-Acetoxyscirpenol Caspase
15-Acetoxyscirpenol, a member of the acetoxyscirpenol moiety mycotoxins (ASMs), potently induces apoptosis and inhibits the growth of Jurkat T cells in a dose-dependent manner. This effect is mediated through the activat...
T75632 Ganoderic acid T1
Ganoderic acid T1, a deacetylated derivative of Ganoderic acid T, diminishes mitochondrial membrane potential and triggers cell apoptosis by activating caspase-9 and caspase-3, thus impairing the antioxidant defense syst...
T79992 Sarglaroids F Caspase
Sarglaroids F (compound 6), an anti-inflammatory agent extracted from the roots of Grass Coral, suppresses LPS/ATP-induced IL-1β secretion by modulating K+ efflux and diminishing Caspase-1(P20) concentrations. Additional...
TN5033 Skullcapflavone I IL Receptor , Caspase , Prostaglandin Receptor
Skullcapflavone I has anti-inflammatory and anti-allergic potential, it can significantly inhibit LPS stimulated NO and PGE(2) release in J774A.1 macrophages and inhibit LPS induced IL-6 production in a concentration dep...
T73876 Sanggenon G
Sanggenon G, a cell-permeable and potent inhibitor of X-linked inhibitor of apoptosis protein (XIAP), specifically binds to the XIAP BIR3 domain with a binding affinity of 34.26 μM, thereby enhancing caspase activation [...
T80656 Cannflavin A
Cannflavin A, isolated from Cannabis sativa L., exhibits anti-cancer, neuroprotective, and anti-inflammatory activities by inhibiting Aβ1-42 aggregation and kynurenine-3-monooxygenase (KMO), as well as inducing apoptosis...
T38838 QS-21 Stimulon,QS-21
QS-21, an immunostimulatory saponin, is a powerful vaccine adjuvant that stimulates both Th2 humoral and Th1 cell-mediated immune responses by interacting with antigen presenting cells (APCs) and T cells. Additionally, Q...
T79941 Antimycin A2c Apoptosis
Anticancer Agent 141 (Compound AE), an antimycin alkaloid, exhibits inhibitory potential against HPV-infected cervical cancer. It impedes HeLa cell proliferation by arresting the cell cycle at the S phase and induces cas...
TN6515 Selaginellin
Selaginellin has a neuroprotective effect against L-glutamate-induced neurotoxicity through mechanisms related to anti-oxidation and anti-apoptosis via scavenging reactive oxygen species and up-regulating the expression ...
T36954 Nemorosone
Nemorosone is a polycyclic polyprenylated acylphloroglucinol (PPAP) originally isolated from C. rosea that has antiproliferative properties.1 Nemorosone inhibits growth of NB69, Kelly, SK-N-AS, and LAN-1 neuroblastoma ce...

Natural Products

(S)-10-Hydroxycamptothecin
T2764
Synonym: 10-Hydroxycamptothecin,10-HCPT
Target: Apoptosis, Topoisomerase
Daphnetin
T2851
Synonym: 7,8-Dihydroxycoumarin,Daphnetol
Target: EGFR, PKA, PKC, Parasite, Autophagy
Paris saponin VII
T4085
Synonym: Chonglou Saponin VII,Polyphyllin-VII,Dioscinin,Paris saponin-VII
Target: Apoptosis, BCL, Others, PARP, p38 MAPK, Akt, Caspase, P-gp, Autophagy
Isoacteoside
T3892
Synonym: Isoverbascoside
Target: NF-κB
Lucidenic acid B
TN1880
Synonym: Lucidenicacid B
Target: Apoptosis, Caspase
Sesamolin
T5S2283
Synonym:
Target: p38 MAPK, Caspase, JNK
Soyasaponin Bb
T3S0335
Synonym: Soyasaponin I
Target: NF-κB, Caspase
Daphnoretin
T4S1335
Synonym: Dephnoretin,Thymelol
Target: Influenza Virus, Caspase, PKC
Rottlerin
T16791
Synonym: Mallotoxin,NSC 56346,NSC 94525
Target: CaMK, Apoptosis, Others, HIV Protease, PKA, PKC, Autophagy
Mulberroside A
T6S1597
Synonym:
Target: TNF, Tyrosinase, Interleukin
Aristolactam I
T3S1227
Synonym: Aristolactam,Aristololactam I,Aristololactum
Target: Apoptosis, Caspase
Dehydrocorydaline nitrate
T2S2362
Synonym:
Target: BCL, Others, PARP, p38 MAPK, Caspase, Parasite, Autophagy
Polyphyllin VI
T6S2315
Synonym:
Target: Apoptosis, Antibacterial, Pyroptosis
Saikosaponin A
T2768
Synonym:
Target: NF-κB, Antibacterial, Liver X Receptor
Fraxetin
T2909
Synonym: 7,8-dihydroxy-6-methoxy coumarin
Target: Apoptosis, Others
5,7-Dihydroxychromone
T5S1805
Synonym: 5,7-Dihydroxy-4H-Chromen-4-One
Target: Others, Virus Protease, PARP, Caspase, Nrf2
Dehydrocorydaline
T5S2358
Synonym: Dehydrocorydalin,13-Methylpalmatine
Target: BCL, PARP, p38 MAPK, Caspase, Parasite, Autophagy
β,β-Dimethylacrylshikonin
T3S2344
Synonym: Dimethylacrylshikonin,β, β-Dimethylacrylshikonin
Target: ERK, HIF/HIF Prolyl-Hydroxylase
Orientin
T6S0721
Synonym: Lutexin,Luteolin-8-glucoside
Target: Others
Barlerin
T5S1632
Synonym: 8-O-Acetylshanzhiside methyl ester,ND01
Target: VEGFR, TNF, NF-κB, Akt, Caspase
Glaucocalyxin A
T4S0498
Synonym: Wangzaozin B,Leukamenin F
Target: Apoptosis, Akt, Caspase, PI3K
Ginkgetin
T4S2126
Synonym:
Target: Apoptosis, Wnt/beta-catenin, COX, STAT, Autophagy
Cornuside
T4S2326
Synonym: 7-Galloylsecologanol,7-O-Galloylsecologanol,Comuside
Target: ERK, p38 MAPK, NF-κB, JNK
Chelidonic acid
T5558
Synonym: Jervaic acid,Jerva acid,γ-Pyrone-2,6-dicarboxylic acid
Target: NF-κB, Caspase
Koumine
T5S0661
Synonym:
Target: Others
Chelidonine
T5S0055
Synonym: Helidonine,Khelidonin,Stylophorin
Target: Apoptosis, Others, Influenza Virus
15-Acetoxyscirpenol
T14003
Synonym:
Target: Caspase
Ganoderic acid T1
T75632
Synonym:
Target:
Sarglaroids F
T79992
Synonym:
Target: Caspase
Skullcapflavone I
TN5033
Synonym:
Target: IL Receptor, Caspase, Prostaglandin Receptor
Sanggenon G
T73876
Synonym:
Target:
Cannflavin A
T80656
Synonym:
Target:
QS-21
T38838
Synonym: Stimulon,QS-21
Target:
Antimycin A2c
T79941
Synonym:
Target: Apoptosis
Selaginellin
TN6515
Synonym:
Target:
Nemorosone
T36954
Synonym:
Target:

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPH-01055 Caspase-1 Protein, Human, Recombinant (HA) Human E. coli
Caspase-1 Protein, Human, Recombinant (HA) is expressed in E. coli expression system with C-HA tag. The predicted molecular weight is 11.4 kDa and the accession number is P29466.
TMPY-02831 Caspase-7 Protein, Human, Recombinant (His) Human E. coli
Caspase 7, also known as caspase-7 and MCH3, belongs to the cysteine-aspartic acid protease (caspase) family. Caspases play a role in the signal transduction pathways of apoptosis, necrosis and inflammation. There are tw...
TMPH-01056 Caspase-3 Protein, Human, Recombinant (His) Human E. coli
Caspase-3 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 20.6 kDa and the accession number is P42574.
TMPK-00277 TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant (hFc) Human HEK293 Cells
DR5, also called TRAIL R2, TRICK 2, TNFRSF10B, and MK is a type 1 TNF R superfamily, membrane protein which is a receptor for TRAIL (APO2 ligand). DR5 is a receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter mol...
TMPH-02521 PYCARD Protein, Mouse, Recombinant (His & Myc) Mouse E. coli
Functions as key mediator in apoptosis and inflammation. Promotes caspase-mediated apoptosis involving predominantly caspase-8 and also caspase-9 in a probable cell type-specific manner. Involved in activation of the mit...
TMPY-00507 UNC5B Protein, Human, Recombinant (hFc) Human HEK293 Cells
The netrin-1 receptor, UNC-5 Homology B, or UNC5B plays vital roles in angiogenesis, inflammation, embryonic development and carcinogenesis. Overexpression of UNC5B human colon epithelial cells suppressed dextran sodium ...
TMPJ-01256 Caspase-10 Protein, Human, Recombinant (His) Human E. coli
Caspase-10 (CASP10) is a 521 amino acid protein member of the Cysteine-Aspartic Acid Protease (Caspase) family. CASP10 contains two DED (Death Effector) domains and is detectable in most tissues. CASP10 cleavage by Granz...
TMPY-04133 UNC5B Protein, Human, Recombinant (His) Human HEK293 Cells
The netrin-1 receptor, UNC-5 Homology B, or UNC5B plays vital roles in angiogenesis, inflammation, embryonic development and carcinogenesis. Overexpression of UNC5B human colon epithelial cells suppressed dextran sodium ...
TMPK-00276 TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant (His & Avi) Human HEK293 Cells
DR5, also called TRAIL R2, TRICK 2, TNFRSF10B, and MK is a type 1 TNF R superfamily, membrane protein which is a receptor for TRAIL (APO2 ligand). DR5 is a receptor for the cytotoxic ligand TNFSF10/TRAIL. The resulting d...
TMPY-02213 RAIDD Protein, Human, Recombinant (His) Human E. coli
Death domain-containing protein CRADD, also known as Caspase and RIP adapter with death domain, RIP-associated protein with a death domain, CRADD and RAIDD, is a protein which is constitutively expressed in most tissu...
TMPJ-00697 NOL3 Protein, Human, Recombinant (GST) Human E. coli
Nucleolar Protein 3 is encoded by NOL3 gene; multiple transcript variants encoding different isoforms have been found for this gene. So far, Nucleolar protein 3 has show to have two Isoforms. Isoform 1 may be involved in...
TMPJ-00358 DR6 Protein, Mouse, Recombinant (hFc & His) Mouse HEK293 Cells
Tumor necrosis factor receptor superfamily member 21(DR6) is a single-pass type I membrane protein and contains 1 death domain and 4 TNFR-Cys repeats. The protein may activate NF-kappa-B and promote apoptosis and it may ...
TMPJ-00718 AIF Protein, Human, Recombinant (His) Human E. coli
Apoptosis-Inducing Factor 1, Mitochondrial (AIFM1) is a flavoprotein essential for nuclear disassembly in apoptotic cells that is found in the mitochondrial intermembrane space in healthy cells. During apoptosis, it is t...
TMPJ-00215 Fas/CD95 Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
Mouse Apoptosis-mediating surface antigen FAS (Fas) belongs to the death receptor subfamily of the TNF receptor superfamily and is designated TNFRSF6. Mouse Fas contains 1 death domain and 3 TNFR-Cys repeats. It detected...
TMPJ-00696 NOL3 Protein, Human, Recombinant Human E. coli
Nucleolar protein 3 is encoded by NOL3 gene. Multiple transcript variants encoding different isoforms have been found for this gene. So far, Nucleolar protein 3 has show to have two Isoforms. Isoform 1 may be involved in...
TMPK-00515 IL-1 beta/IL-1F2 Protein, Cynomolgus, Recombinant (His) Cynomolgus E. coli
Interleukin-1 beta (IL-1β) is induced by inflammatory signals in a broad number of immune cell types. IL-1β (and IL-18) are the only cytokines which are processed by caspase-1 after inflammasome-mediated activation. IL-1...
TMPK-00161 IL-1 beta/IL-1F2 Protein, Human, Recombinant (His & Avi) Human E. coli
Interleukin-1 beta (IL-1β) is induced by inflammatory signals in a broad number of immune cell types. IL-1β (and IL-18) are the only cytokines which are processed by caspase-1 after inflammasome-mediated activation. IL-1...
TMPY-04003 UNC5B Protein, Rat, Recombinant (hFc) Rat HEK293 Cells
The netrin-1 receptor, UNC-5 Homology B, or UNC5B plays vital roles in angiogenesis, inflammation, embryonic development and carcinogenesis. Overexpression of UNC5B human colon epithelial cells suppressed dextran sodium ...
TMPK-00162 IL-1 beta/IL-1F2 Protein, Human, Recombinant (His & Avi), Biotinylated Human E. coli
Interleukin-1 beta (IL-1β) is induced by inflammatory signals in a broad number of immune cell types. IL-1β (and IL-18) are the only cytokines which are processed by caspase-1 after inflammasome-mediated activation. IL-1...
TMPJ-00770 Granzyme B/GZMB Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
Granzyme B(GZMB) contains 1 peptidase S1 domain and belongs to the peptidase S1 family. This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp and seems to be linked to an...
TMPY-01775 AIM2 Protein, Human, Recombinant (GST) Human Baculovirus Insect Cells
AIM2, Absent In Melanoma 2 is a member of the interferon-inducible HIN-200 protein family that contains an amino-terminal pyrin domain and a carboxy-terminal oligonucleotide/oligosaccharide-binding domain, senses cytopla...
TMPY-01176 CIAP1 Protein, Human, Recombinant (Avi) Human E. coli
The cellular inhibitor of apoptosis protein-1 (cIAP1) is a member of the Inhibitor of Apoptosis family proteins are (IAP) whose members are characterized by a novel domain of about 70 amino acids termed baculoviral IAP r...
TMPJ-01066 CYCS Protein, Human, Recombinant (His) Human E. coli
Cytochrome C (CYCS) is a small heme protein that belongs to the cytochrome c family. It is found loosely associated with the inner membrane of the mitochondrion. Cytochrome C is a highly soluble protein that functions as...
TMPY-00924 SMAC Protein, Human, Recombinant (His) Human E. coli
Apoptosis is an essential processes required for normal development and homeostasis of all metazoan organisms. Second Mitochondria-Derived Activator of Caspases (Smac) or Direct IAP Binding Protein with low isoelectric p...
TMPY-04451 AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) Human Baculovirus Insect Cells
AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 160 kDa and the accession number is P54619-1&Q9Y478-1&...
TMPY-03878 Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His) Human HEK293 Cells
Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 190.4 kDa and the accession number is P06756-1&P18564-1.
TMPY-02501 CD3D & CD3E Heterodimer Protein, Human, Recombinant Human HEK293 Cells
CD3D & CD3E Heterodimer Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 77.5 kDa and the accession number is P04234-1&P07766-1.
TMPY-03745 CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His) Human HEK293 Cells
CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 31.05 kDa and the accession number is P04234-1&P07766-1.
TMPY-03958 TGF alpha Protein, Human, Recombinant Human E. coli
The miR-137 served as a tumor suppressor in non-small cell lung cancer (NSCLC) and its suppressive effect is mediated by repressing TGFA expression. TGFA gene expression was significantly higher in tumor tissues compared...
TMPY-04069 Neurotrophin 3 Protein, Human, Recombinant Human E. coli
NTF3 (Neurotrophin 3) is a Protein Coding gene. The protein encoded by this gene is a member of the neurotrophin family, that controls the survival and differentiation of mammalian neurons. This protein is closely relate...
TMPY-02907 FGF-19 Protein, Human, Recombinant Human E. coli
FGF19, also known as FGF-19, is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, inclu...
TMPK-00383 ACE2/ACEH Protein, Human, Recombinant (His & Avi) Human HEK293 Cells
ACE2 (Angiotensin I Converting Enzyme 2) is a Protein Coding gene. Diseases associated with ACE2 include Severe Acute Respiratory Syndrome and Neurogenic Hypertension.The protein encoded by this gene belongs to the angio...
TMPY-01459 TNFR1/CD120a/TNFRSF1A Protein, Human, Recombinant (His) Human HEK293 Cells
TNFR1/CD120a/TNFRSF1A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.7 kDa and the accession number is P19438-1.
TMPY-01827 CD30/TNFRSF8 Protein, Human, Recombinant (His) Human HEK293 Cells
CD30/TNFRSF8 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is P28908-1.
TMPY-01776 Carboxylesterase 2/CES2 Protein, Human, Recombinant (His) Human HEK293 Cells
Carboxylesterase 2/CES2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 60.4 kDa and the accession number is O00748-1.
TMPY-02019 CD59 Protein, Human, Recombinant (His) Human HEK293 Cells
CD59 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 10.2 kDa and the accession number is P13987-1.
TMPY-01461 EMAP-II/AIMP1 Protein, Human, Recombinant (His) Human E. coli
EMAP-II/AIMP1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 35 kDa and the accession number is Q12904-1.
TMPY-00972 FGFR2 Protein, Human, Recombinant (His & hFc) Human HEK293 Cells
FGFR2 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 67.6 kDa and the accession number is P21802-1.
TMPY-01104 Coagulation factor XI/F11 Protein, Human, Recombinant (His) Human HEK293 Cells
Factor XI (plasma thromboplastin antecedent) is a plasma glycoprotein, and a zymogen acting as a serine protease which participates in blood coagulation as a catalyst in the conversion of factor IX to factor IXa in the p...
TMPY-01912 Cadherin 17/CDH17 Protein, Human, Recombinant (His) Human HEK293 Cells
Cadherin 17/CDH17 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 87 kDa and the accession number is Q12864-1.
TMPY-02031 B7-H3 Protein, Human, Recombinant (His) Human HEK293 Cells
B7-H3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 48 kDa and the accession number is Q5ZPR3-1.
TMPY-02525 RGMA Protein, Human, Recombinant (His) Human HEK293 Cells
RGMa, also known as RGM domain family, member A, belongs to the RGM (repulsive guidance molecule) family whose members are membrane-associated glycoprotein. RGMa is a glycosylphosphatidylinositol-anchored glycoprotein th...
TMPY-04262 B7-H3 Protein, Human, Recombinant (His), Biotinylated Human HEK293 Cells
B7-H3 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 48 kDa and the accession number is Q5ZPR3-1.
TMPY-00915 Serpin A1 Protein, Human, Recombinant (His) Human HEK293 Cells
Serpin A1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 45.7 kDa and the accession number is P01009-1.
TMPY-02836 MFGE8 Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
MFGE8 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 42 kDa and the accession number is Q08431-1.
TMPY-01462 IL-11R alpha/IL-11RA Protein, Human, Recombinant (His) Human HEK293 Cells
IL-11R alpha/IL-11RA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.6 kDa and the accession number is Q14626-1.
TMPK-00176 BAFF/TNFSF13B Trimer Protein, Human, Recombinant (His & Flag) Human HEK293 Cells
B-cell activating factor (BAFF) also known as tumor necrosis factor ligand superfamily member 13B is a protein that in humans is encoded by the TNFSF13B gene.BAFF is a cytokine that belongs to the tumor necrosis factor (...
TMPY-02034 Siglec-2/CD22 Protein, Human, Recombinant (His) Human HEK293 Cells
Siglec-2/CD22 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 76.6 kDa and the accession number is P20273-1.
TMPY-02794 TLR2 Protein, Human, Recombinant (aa 1-587, His) Human Baculovirus Insect Cells
TLR2 Protein, Human, Recombinant (aa 1-587, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 65.5 kDa and the accession number is O60603-1.
TMPY-04799 IFNAR2 Protein, Human, Recombinant (His), Biotinylated Human HEK293 Cells
IFNAR2 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.2 kDa and the accession number is P48551-1.
------------------------ More ------------------------
Caspase-1 Protein, Human, Recombinant (HA)
TMPH-01055
Species: Human
Expression System: E. coli
Caspase-7 Protein, Human, Recombinant (His)
TMPY-02831
Species: Human
Expression System: E. coli
Caspase-3 Protein, Human, Recombinant (His)
TMPH-01056
Species: Human
Expression System: E. coli
TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant (hFc)
TMPK-00277
Species: Human
Expression System: HEK293 Cells
PYCARD Protein, Mouse, Recombinant (His & Myc)
TMPH-02521
Species: Mouse
Expression System: E. coli
UNC5B Protein, Human, Recombinant (hFc)
TMPY-00507
Species: Human
Expression System: HEK293 Cells
Caspase-10 Protein, Human, Recombinant (His)
TMPJ-01256
Species: Human
Expression System: E. coli
UNC5B Protein, Human, Recombinant (His)
TMPY-04133
Species: Human
Expression System: HEK293 Cells
TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant (His & Avi)
TMPK-00276
Species: Human
Expression System: HEK293 Cells
RAIDD Protein, Human, Recombinant (His)
TMPY-02213
Species: Human
Expression System: E. coli
NOL3 Protein, Human, Recombinant (GST)
TMPJ-00697
Species: Human
Expression System: E. coli
DR6 Protein, Mouse, Recombinant (hFc & His)
TMPJ-00358
Species: Mouse
Expression System: HEK293 Cells
AIF Protein, Human, Recombinant (His)
TMPJ-00718
Species: Human
Expression System: E. coli
Fas/CD95 Protein, Mouse, Recombinant (hFc)
TMPJ-00215
Species: Mouse
Expression System: HEK293 Cells
NOL3 Protein, Human, Recombinant
TMPJ-00696
Species: Human
Expression System: E. coli
IL-1 beta/IL-1F2 Protein, Cynomolgus, Recombinant (His)
TMPK-00515
Species: Cynomolgus
Expression System: E. coli
IL-1 beta/IL-1F2 Protein, Human, Recombinant (His & Avi)
TMPK-00161
Species: Human
Expression System: E. coli
UNC5B Protein, Rat, Recombinant (hFc)
TMPY-04003
Species: Rat
Expression System: HEK293 Cells
IL-1 beta/IL-1F2 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00162
Species: Human
Expression System: E. coli
Granzyme B/GZMB Protein, Mouse, Recombinant (His)
TMPJ-00770
Species: Mouse
Expression System: HEK293 Cells
AIM2 Protein, Human, Recombinant (GST)
TMPY-01775
Species: Human
Expression System: Baculovirus Insect Cells
cIAP1 Protein, Human, Recombinant (Avi)
TMPY-01176
Species: Human
Expression System: E. coli
CYCS Protein, Human, Recombinant (His)
TMPJ-01066
Species: Human
Expression System: E. coli
SMAC Protein, Human, Recombinant (His)
TMPY-00924
Species: Human
Expression System: E. coli
AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST)
TMPY-04451
Species: Human
Expression System: Baculovirus Insect Cells
Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His)
TMPY-03878
Species: Human
Expression System: HEK293 Cells
CD3D & CD3E Heterodimer Protein, Human, Recombinant
TMPY-02501
Species: Human
Expression System: HEK293 Cells
CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His)
TMPY-03745
Species: Human
Expression System: HEK293 Cells
TGF alpha Protein, Human, Recombinant
TMPY-03958
Species: Human
Expression System: E. coli
Neurotrophin 3 Protein, Human, Recombinant
TMPY-04069
Species: Human
Expression System: E. coli
FGF-19 Protein, Human, Recombinant
TMPY-02907
Species: Human
Expression System: E. coli
ACE2/ACEH Protein, Human, Recombinant (His & Avi)
TMPK-00383
Species: Human
Expression System: HEK293 Cells
TNFR1/CD120a/TNFRSF1A Protein, Human, Recombinant (His)
TMPY-01459
Species: Human
Expression System: HEK293 Cells
CD30/TNFRSF8 Protein, Human, Recombinant (His)
TMPY-01827
Species: Human
Expression System: HEK293 Cells
Carboxylesterase 2/CES2 Protein, Human, Recombinant (His)
TMPY-01776
Species: Human
Expression System: HEK293 Cells
CD59 Protein, Human, Recombinant (His)
TMPY-02019
Species: Human
Expression System: HEK293 Cells
EMAP-II/AIMP1 Protein, Human, Recombinant (His)
TMPY-01461
Species: Human
Expression System: E. coli
FGFR2 Protein, Human, Recombinant (His & hFc)
TMPY-00972
Species: Human
Expression System: HEK293 Cells
Coagulation factor XI/F11 Protein, Human, Recombinant (His)
TMPY-01104
Species: Human
Expression System: HEK293 Cells
Cadherin 17/CDH17 Protein, Human, Recombinant (His)
TMPY-01912
Species: Human
Expression System: HEK293 Cells
B7-H3 Protein, Human, Recombinant (His)
TMPY-02031
Species: Human
Expression System: HEK293 Cells
RGMA Protein, Human, Recombinant (His)
TMPY-02525
Species: Human
Expression System: HEK293 Cells
B7-H3 Protein, Human, Recombinant (His), Biotinylated
TMPY-04262
Species: Human
Expression System: HEK293 Cells
Serpin A1 Protein, Human, Recombinant (His)
TMPY-00915
Species: Human
Expression System: HEK293 Cells
MFGE8 Protein, Human, Recombinant (His)
TMPY-02836
Species: Human
Expression System: Baculovirus Insect Cells
IL-11R alpha/IL-11RA Protein, Human, Recombinant (His)
TMPY-01462
Species: Human
Expression System: HEK293 Cells
BAFF/TNFSF13B Trimer Protein, Human, Recombinant (His & Flag)
TMPK-00176
Species: Human
Expression System: HEK293 Cells
Siglec-2/CD22 Protein, Human, Recombinant (His)
TMPY-02034
Species: Human
Expression System: HEK293 Cells
TLR2 Protein, Human, Recombinant (aa 1-587, His)
TMPY-02794
Species: Human
Expression System: Baculovirus Insect Cells
IFNAR2 Protein, Human, Recombinant (His), Biotinylated
TMPY-04799
Species: Human
Expression System: HEK293 Cells
Cat No. Product Name
L8720 Pyroptosis Compound Library

1066 compounds
1066 types of active small molecules associated with pyroptosis for high-throughput and high-content screening.
TargetMol