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Daphnetin

Catalog No. T2851    CAS 486-35-1    Synonyms: 7,8-Dihydroxycoumarin, Daphnetol

Daphnetin, a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM), and PKC (IC50: 25.01 μM), also exhibit anti-oxidant and anti-inflammatory activities.

Pack Size Availability Price/USD Quantity
10 mg In stock 50.00
25 mg In stock 115.00
100 mg In stock 340.00
200 mg Inquiry 505.00
1 mL * 10 mM (in DMSO) In stock 50.00
Bulk Size: Please Quote for Discount Please Quote for Bulk Size
Biological Activity:

Product Description:

Daphnetin, a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM), and PKC (IC50: 25.01 μM), also exhibit anti-oxidant and anti-inflammatory activities.

Receptor:

EGFR; PKA; PKC;

Chemical Information:
Molecular Weight 178.14
Formula C9H6O4
CAS Number 486-35-1
Solubility

DMSO: 33 mg/mL (185.2 mM)

Ethanol: <1 mg/mL

Water: <1 mg/mL

( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage store at -80°C
Remark For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ℃ for several month.
Technical Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.

Reference
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