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Apoptosis Caspase Ac-DEVD-CHO

Ac-DEVD-CHO

Catalog No. TQ0146   CAS 169332-60-9

Ac-DEVD-CHO is a selective Caspase-3 inhibitor (Ki: 230 pM).

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Ac-DEVD-CHO, CAS 169332-60-9
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50 mg Inquiry 1013.00
100 mg Inquiry 1655.00
200 mg Inquiry 2483.00
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Ac-DEVD-CHO is a selective Caspase-3 inhibitor (Ki: 230 pM).
Molecular Weight 502.47
Formula C20H30N4O11
CAS No. 169332-60-9

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 6 months

Solubility Information

Water: 50 mg/mL (99.51 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )

Citations

References and Literature
1. Garcia-Calvo M, et al.nhibition of human caspases by peptide-based and macromolecular inhibitors. J Biol Chem. 1998 Dec 4;273(49):32608-13. 2. Jinglin Wang, et al. A polysaccharide from Lentinus edodes inhibits human colon cancer cell proliferation and suppresses tumor growth in athymic nude mice. Oncotarget. 2017 Jan 3; 8(1): 610-623. 3. Long-gang He, et al. Sinomenine induces apoptosis in RAW 264.7 cell-derived osteoclasts in vitro via caspase-3 activation. Acta Pharmacol Sin. 2014 Feb; 35(2): 203-210. 4. Liu LX, et al. The effect of caspase-3 inhibitor on the concentrations of serum inflammatory cytokines in sepsis related acute kidney injury induced by peritoneal cavity infection in mice. Zhongguo Wei Zhong Bing Ji Jiu Yi Xue. 2010 Dec;22(12):736-9.

Related Products

Related compounds with same targets
Caspase-3 Inhibitor I Ac-DEVD-CHO Z-WEHD-FMK Z-YVAD-FMK (-)-Zeylenol 1-[2,4-Dihydroxy-6-methoxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-2-propen-1-one Uncarinic acid E Skullcapflavone I

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