Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Saikosaponin A has a variety of pharmacological benefits, including antiepileptic, anti-osteoporosis, antioxidant, anti-in ammatory, immunomodulatory, and anti-bacterial activities. It can effectively attenuate neuropathic pain in CCI rats by inhibiting the activation of p38 MAPK and NF-κB signaling pathways in spinal cord. It can inhibit NMDA receptor current and persistent sodium current, and inhibit the TNF-α level, the IL-1β production, and cysteine-aspartic acid protease (caspase)-1 activity.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 34.00 | |
5 mg | In stock | $ 72.00 | |
10 mg | In stock | $ 126.00 | |
25 mg | In stock | $ 247.00 | |
50 mg | In stock | $ 409.00 | |
100 mg | In stock | $ 596.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 115.00 |
Description | Saikosaponin A has a variety of pharmacological benefits, including antiepileptic, anti-osteoporosis, antioxidant, anti-in ammatory, immunomodulatory, and anti-bacterial activities. It can effectively attenuate neuropathic pain in CCI rats by inhibiting the activation of p38 MAPK and NF-κB signaling pathways in spinal cord. It can inhibit NMDA receptor current and persistent sodium current, and inhibit the TNF-α level, the IL-1β production, and cysteine-aspartic acid protease (caspase)-1 activity. |
Source |
Molecular Weight | 780.98 |
Formula | C42H68O13 |
CAS No. | 20736-09-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (64.02 mM)
Ethanol: 30 mg/mL
H2O: Insoluble
You can also refer to dose conversion for different animals. More
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Saikosaponin A 20736-09-8 Metabolism Microbiology/Virology NF-Κb NF-κB Liver X Receptor Antibacterial inhibit LXR Inhibitor Liver X receptor Bacterial inhibitor