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Diclofenac Potassium

Diclofenac Potassium
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Purity:99.51%
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Diclofenac Potassium

Catalog No. T6470Cas No. 15307-81-0
Diclofenac Potassium (CGP-45840B) is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
25 mg$39In Stock
50 mg$55In Stock
100 mg$80In Stock
200 mg$133In Stock
500 mg$218In Stock
1 mL x 10 mM (in DMSO)$61In Stock
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Related Compound Libraries of "Diclofenac Potassium"

Product Introduction

Bioactivity
Description
Diclofenac Potassium (CGP-45840B) is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions.
In vitro
The primary mechanism of diclofenac responsible for its anti-inflammatory, antipyretic, and analgesic action is thought to be inhibition of prostaglandin synthesis by inhibition of cyclooxygenase (COX). It also appears to exhibit bacteriostatic activity by inhibiting bacterial DNA synthesis. Inhibition of COX also decreases prostaglandins in the epithelium of the stomach, making it more sensitive to corrosion by gastric acid. This is also the main side effect of diclofenac. Diclofenac has a low to moderate preference to block the COX2-isoenzyme (approximately 10-fold) and is said to have, therefore, a somewhat lower incidence of gastrointestinal complaints than noted with indomethacin and aspirin.
AliasCGP-45840B, Cataflam, Voltfast
Chemical Properties
Molecular Weight334.24
FormulaC14H10Cl2KNO2
Cas No.15307-81-0
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
H2O: 10 mg/mL (29.91 mM)
Ethanol: < 1 mg/mL (insoluble or slightly soluble)
DMSO: 55 mg/mL (164.55 mM)
Solution Preparation Table
DMSO/H2O
1mg5mg10mg50mg
1 mM2.9919 mL14.9593 mL29.9186 mL149.5931 mL
5 mM0.5984 mL2.9919 mL5.9837 mL29.9186 mL
10 mM0.2992 mL1.4959 mL2.9919 mL14.9593 mL
20 mM0.1496 mL0.7480 mL1.4959 mL7.4797 mL
DMSO
1mg5mg10mg50mg
50 mM0.0598 mL0.2992 mL0.5984 mL2.9919 mL
100 mM0.0299 mL0.1496 mL0.2992 mL1.4959 mL

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