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Cat No. | Product Name | Synonyms | Targets |
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T8994 | ML-226 | ML226,ML-226 | MAGL |
ML226 is a α/β hydrolase domain-containing protein 11 (ABHD11) inhibitor that inhibits ABHD11 in vitro and in situ. | |||
T3050 | ML-7 hydrochloride | ML-7 HCl | Serine/threonin kinase , Myosin , YAP , PKA , PKC |
ML-7 hydrochloride (ML-7 HCl) is a cell-permeable, reversible, effective, ATP-competitive, and specific inhibitor of myosin light chain kinase (Ki: 300 nM); also inhibits smooth-muscle myosin light chain kinase, PKA, and... | |||
T23002 | ML-335 | Opioid Receptor | |
ML-335 is a μ-δ isomer-targeted agonist, a μOR-δOR-biased ligand that can serve as a scaffold for the development of unique types of (isomer-biased) drugs.ML-335 is a MOR (μ-opioid receptor)/DOR (δ-opioid receptor) heter... | |||
T37587 | ML 209 | ROR | |
ML-209 is an antagonist of retinoic acid receptor-related orphan receptor γt (RORγt; IC50= 1.1 μM in a reporter assay).1It inhibits RORγt-induced transcription in HEK293T cells expressing the human receptor (IC50= 300 nM... | |||
T5496 | ML-030 | PDE | |
ML-030 is a potent and selective inhibitor of PDE4(PDE4A, PDE4A1, PDE4B1, PDE4B2, PDE4C1,and PDE4D2 with IC50 of 6.7 nM, 12.9 nM, 48.2 nM, 37.2 nM, 452 nM and 49.2 nM, respectively) | |||
T4540 | ML-18 | Bombesin Receptor | |
ML-18 is a non-peptide bombesin receptor subtype-3 (BRS-3) antagonist with an IC50 of 4.8 μM. | |||
T36707 | ML 315 | DYRK , CDK | |
ML 315 is a selective Clk and DYRK inhibitor with potential anticancer activity for the study of neurological disorders. | |||
T8974 | ML-211 | Others | |
ML-211 is a carbamate-based dual inhibitor of LYPLA1 (IC50 = 17 nM) and the related LYPLA2 (IC50 = 30 nM) | |||
T60036 | ML-SA5 | Autophagy | |
ML-SA5 is an MCOLN1 agonist and arrests autophagic flux by perturbing fusion between autophagosomes and lysosomes. | |||
T8862 | ML 254 | GluR | |
ML254 competitively interacts with the MPEP allosteric binding site. ML254 is highly selective for mGlu5 versus other mGlu receptors, has a clean ancillary Ricerca profile, and suitable dystrophia myotonica protein kinas... | |||
T40661 | ML-60218 | DNA/RNA Synthesis | |
ML-60218 is an inhibitor of broad-spectrum RNA pol III with IC50s of 32 and 27 μM for Saccharomyces cerevisiae and human. ML-60218 disrupts already assembled viroplasms and hampers the formation of new viroplasms. | |||
T12073 | ML-109 | TSH Receptor | |
ML-109 is a potent agonist of thyroid stimulating hormone receptor (TSHR) (EC50 of 40 nM) | |||
T22991 | ML-099 | Rho , Ras | |
pan activator of Ras-related GTPases | |||
T22994 | ML 154 | Neuropeptide Y Receptor | |
neuropeptide S receptor (NPSR) antagonist | |||
T16104 | ML-9 | Myosin , Akt | |
ML-9 suppresses MLCK, PKA, and PKC activity with Ki values of 4, 32, and 54 μM, respectively. ML-9 is a selective and effective inhibitor of Akt kinase, inhibits myosin light-chain kinase (MLCK), and stromal interaction ... | |||
T38163 | ML-148 | Dehydrogenase | |
ML-148 is a selective inhibitor of 15-hydroxy prostaglandin dehydrogenase (15-PGDH, IC50 = 56 nM). ML-148 can be used to profile across a panel of related dehydrogenase or reductase enzymes and in studies about prostagla... | |||
T22990 | ML-090 | Fluoflavine | NADPH-oxidase , Others |
ML-090 is NOX1-specific inhibitor(IC50 = 90 nM) which is >100 selectivity for NOX1 over NOX2, NOX3, NOX4 (all IC50s >10 μM). | |||
T22996 | ML-191 | ERK | |
ML-191 is an inhibitor of LPI-induced phosphorylation of ERK1/2. | |||
T21970 | ML-097 | GTPase | |
ML-097 (CID-2160985) is a pan activator of Ras-related GTPases | |||
T4619 | ML-098 | CID-7345532 | Ras |
ML-098 (CID-7345532) is an activator of the GTP-binding protein Rab7 (EC50: 77.6 nM). | |||
T22101 | ML-031 | S1P Receptor | |
ML-031 activated S1P2 with an EC50 value of 1 μM in an S1P reporter assay. | |||
T8571 | ML-184 | CID2440433 | Cannabinoid Receptor |
ML-184 (CID2440433) is a potent synthetic agonist of GPR55 with EC50 of 0.26 μM. | |||
T8375 | ML-210 | CID 49766530 | Ferroptosis , GPX , Glutathione Peroxidase , Ras |
ML-210 (CID 49766530) is a selective RAS and covalent glutathione peroxidase 4 (GPX4) inhibitor(GPX4, EC50 : 30 nM), with anti-cancer activity | |||
T12075 | ML-180 | SR1848 | Others |
ML-180 (SR1848) is a potent orphan nuclear receptor liver receptor homolog 1 (LRH-1; NR5A2) inverse agonist (IC50 of 3.7 μM) . | |||
T22102 | ML-178 | CYM50179 | Others |
ML-178, a dichlorobenzene, is a potent and selective agonist of sphingosine-1-phosphate receptor 4 (S1PR4), with an EC50 of 46 nM, and has no effect on other S1P receptors at a concentration of 25 μM. | |||
T23004 | ML-SA1 | Mucolipin synthetic agonist 1 | Others , TRP/TRPV Channel |
ML-SA1 (Mucolipin synthetic agonist 1) is a selective TRPML agonist, inhibits Dengue virus 2 (DENV2) and Zika virus (ZIKV) by promoting lysosomal acidification and protease activity. The IC50 value of ML-SA1 against DENV... | |||
T22992 | ML 10302 hydrochloride | 5-HT Receptor | |
ML 10302 hydrochloride is a specific agonist 5-HT4 and binds 5-HT receptors with Kis of 1.07 nM and 782 nM for 5-HT4 and 5-HT3. | |||
T21900 | ML-336 | Others | |
ML-336 is an inhibitor of of the Venezuelan equine encephalitis virus (VEEV) strain TC-83. | |||
T1757 | ML-323 | ML323 | DUB |
ML323 is a reversible and effective USP1-UAF1 inhibitor in a Ub-Rho assay (IC50: 76 nM) and in orthogonal gel-based assays using K63-linked diubiquitin (di-Ub) (IC50: 174 nM 820 nM)and monoubiquitinated PCNA (Ub-PCNA) (I... | |||
T8966 | ML-298 | ML298,CID53393915 | Phospholipase |
ML-298 (CID53393915) is a potent, specific inhibitor of Phospholipase D2 (PLD2, IC50 of 355 nM). | |||
T21969 | ML-095 hydrochloride | CID-25067483 hydrochloride,MLS-0315848 hydrochloride | Phospholipase |
ML-095 hydrochloride (CID-25067483 hydrochloride) is a specific placental alkaline phosphatase inhibitor. It inhibits PLAP, TNAP and IAP with IC50 of 2.1, >100 and 53 μM, respectively. | |||
T4664 | ML 297 | ML297 | Potassium Channel |
ML 297 is a selective Kir3.1/3.2 (GIRK1/2) channel activator (IC50 values are 160, 887 and 914 nM for GIRK1/2, GIRK1/4 and GIRK1/3 respectively). ML 297 exhibits no effect on GIRK2, GIRK2/3, Kir2.1 and Kv7.4 channels, an... | |||
T16102 | ML-792 | E1/E2/E3 Enzyme | |
ML-792 is a specific small ubiquitin-like modifier (SUMO)-activating enzyme (SAE) inhibitor. Compared with NAE/NEDD8 and UAE/ubiquitin (IC50s of 32 μM and >100 μM, respectively), ML-792 is an effective and selective inhi... | |||
T22103 | ML-193 | CID 1261822 | Cannabinoid Receptor |
ML-193 (CID 1261822) is a potent and selective GPR55 antagonist( IC50 : 221 nM). It shows more than 27-fold selectivity for GPR55 over GPR35, CB1 and CB2, and can improve the motor and the sensorimotor deficits of Parkin... | |||
T1893 | Parmodulin 2 | ML 161 | Protease-activated Receptor |
Parmodulin 2 (ML 161) is the inhibitor of protease-activated receptor 1 (PAR1)-mediated platelet activation (IC50: 0.26 μM for the inhibition of platelet P-selectin expression on human platelets). It also inhibits thromb... | |||
T25821 | ML359 | ML-359,ML 359 | Others |
ML359 is a protein disulfide isomerase inhibitor. | |||
T28069 | ML380 | ML 380,ML-380 | AChR |
ML380 is a highly potent and the first CNS penetrant M5 positive allosteric modulator (PAM). | |||
T23003 | ML337 | ML 337 | GluR |
ML337 is a negative allosteric modulator of mGlu3 with an IC50 of 593 nM. | |||
T33450 | ML 23 | ML-23,ML23 | |
ML 23 is a melatonin analogue in the treatment and management of Parkinson's disease. ML-23 is a potential clinical candidate for the treatment of PD, and the present study has been undertaken to determine the efficacy o... | |||
T33449 | ML 1035 | ML103,ML-1035 | |
ML 1035 is a benzamide that elicits contractions from guinea-pig non-stimulated ileum. | |||
T33448 | ML 10 | ML-10,ML10 | |
ML 10 is is a [18F] positron emission tomography (PET) radiotracer that accumulates in cells presenting apoptosis-specific membrane alterations. [18F]ML-10 allows for the detection of apoptotic cells located in atheroscl... | |||
T33451 | ML 7 | ML7,ML-7 | |
ML 7 is an inhibitor of myosin light chain kinase that protects cardiac function from ischemia/reperfusion (I/R) injury. | |||
T8954 | ML179 | ML-179 | Others |
ML179 is a potent and selective inverse agonist of liver receptor homolog-1 (LRH1, NR5A2) with IC50 of 320 nM. | |||
T23000 | ML289 | VU0463597,ML 289 | GluR |
ML289 (VU0463597) is a potent, selective, and CNS-penetrant negative allosteric modulator of mGlu3 (IC50=0.66 μM), demonstrating over 15-fold selectivity compared to mGlu2 and showing no activity against mGlu5. | |||
T6568 | Licofelone | ML-3000 | Apoptosis , Lipoxygenase , COX |
Licofelone (ML-3000) is a dual COX/LOX inhibitor potentially for the treatment of osteoarthritis. Licofelone is both an analgesic and an anti-inflammatory. Inhibition of 5-LOX may reduce the gastrointestinal toxicity ass... | |||
T9011 | VU0155094 | ML 397,ML-397,VU 0155094,VU-0155094 | GluR |
VU0155094 (ML 397) is a positive allosteric modulator with differential activity at the various group III mGluRs. | |||
T5160 | SR3335 | ML 176 | ROR |
SR3335 (ML 176) is a selective inverse agonist of RORα, competitively inhibiting the binding of 25-hydroxycholesterol to the ligand binding domain (Ki: 220 nM). | |||
T25824 | ML400 | ML 400,CID-73050863,ML-400,CID73050863,CID 73050863 | Phosphatase |
ML400 (CID73050863) is an allosteric inhibitor of LMPTP with an EC50 of 1μM. ML400 displays good cell-based activity and rodent pharmacokinetics. | |||
T7596 | Firocoxib | ML 1785713 | COX |
Firocoxib (ML 1785713) is a selective non-steroidal inhibitor of cycooxygenase-2 (COX-2) (IC50 of 0.13 μM), with anti-inflammatory for use in dogs and horses. | |||
T33452 | ML192 | ML-192,CID1434953,CID 1434953,ML 192,CID-1434953 | Cannabinoid Receptor , GPR , Arrestin |
ML192 (CID1434953) is a selective GPR55 ligand antagonist. ML192 is an inhibitor that inhibits β-arrestin transport, ERK1/2 phosphorylation, and PKCβII translocation. |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T3629 | Gamithromycin | ML-1709460 | Antibacterial , Antibiotic |
Gamithromycin (ML-1709460) is a macrolide compound with antibacterial activity. | |||
T16012 | Marizomib | NPI-0052,Salinosporamide A,ML858 | Proteasome |
Marizomib (ML858) is a novel irreversible brain-permeable proteasome inhibitor that inhibits CT-L (β5), CT-T-laspase-like (C-L, β1), and trypsin-like (T-L, β2) 20S proteasomes with IC50s of 3.5, 28, and 430 nM, respectiv... | |||
TN6302 | Illiciumlignan D | ||
Illiciumlignan D is a natural product for research related to life sciences. The catalog number is TN6302 and the CAS number is 2237239-36-8. | |||
T2843 | Aloe emodin | NSC 38628,3-Hydroxymethylchrysazine,Rhabarberone,Aloe-emodin | Autophagy , HSV |
Aloe emodin (Rhabarberone) is an interferon-inducing agent, for JEV (IC50=1 μg/mL) and EV71(IC50=0.33 μg/mL ). | |||
T14329 | Ascamycin | Nucleoside Antimetabolite/Analog , Others , Antibacterial , Antibiotic | |
Ascamycin is a 5'-O-sulfonamide ribonucleoside antibiotic produced by Streptomyces spp. It shows selective antibacterial activity against Xanthomonas species and inhibits Xanthomonas citri, Xanthomonas oryzae and phage w... | |||
T13708 | Glycol chitosan | Antibacterial | |
Glycol chitosan is a chitosan derivative with hydrophilic ethylene glycol branches. Glycol chitosan inhibits E. coli, S. aureus, and S. enteritidis growths (MICs: 4 μg/mL, 32 μg/mL, and <0.5 μg/mL). It enhances membrane ... | |||
T15277 | Fervenulin | Parasite | |
Fervenulin is isolated from a nematicidal actinomycete Streptomyces sp. CMU-MH021 with nematicidal activity. It also inhibits egg hatch and J2 mortality of M. incognita (MICs: 30 μg/mL and 120 μg/mL, respectively). | |||
T3855 | Tracheloside | Estrogen Receptor/ERR , Phosphorylase | |
Tracheloside significantly decreases the activity of alkaline phosphatase (IC50: 0.31 μg/ml), a level of inhibition comparable to that of tamoxifen (IC50: 0.43 μg/ml). | |||
T8205 | Norwogonin | 5,7,8-Trihydroxyflavone | Virus Protease |
Norwogonin (5,7,8-Trihydroxyflavone), isolated from Scutellaria baicalensis Georgi, possesses antiviral activity against Enterovirus 71 (IC50: 31.83 μg/ml). | |||
TN1091 | Dehydronuciferine | AChE | |
Dehydronuciferine is isolated from the leaves of Nelumbo nucifera Gaertn. Dehydronuciferine shows inhibitory of acetylcholinesterase with the IC50 of 25 ug/mL. | |||
TN3049 | 4-Methoxycinnamyl alcohol | Others | |
4-Methoxycinnamyl alcohol showed toxicity to MCF-7, HeLa and DU145 cancer cell lines with IC50 values of 14.24, 7.82 and 22.10 μg/mL, respectively. 4-Methoxycinnamyl alcohol was isolated from Foeniculum vulgare. 4-Methox... | |||
T2S2169 | Naringenin trimethyl ether | 5,7,4'-Trimethoxyflavanone | Others |
1. Naringenin trimethyl ether (5,7,4'-Trimethoxyflavanone) shows significant molluscicidal activity with a median lethal concentration (LC(5)) of 3.9 μg/mL. | |||
T3792 | Ajugol | Leonuride | Parasite |
Ajugol (Leonuride) shows some trypanocidal potential against Trypanosoma brucei rhodesiense (IC50 values 29.3–73.0 ug/ml). | |||
T13305 | Viridicatol | Anti-infection , Antifungal | |
Viridicatol, with potent antibacterial activity against Staphylococcus aureus(MIC: 15.6 μg/mL), is isolated from the fermentation of an endophytic fungus Penicillium sp. R22 in Nerium indicum. | |||
TQ0217 | Gomisin G | P450 , HIV Protease | |
Gomisin G is a natural compound and exhibits potent anti-HIV activity (EC50: 0.006 μg/mL; therapeutic index: 300). It is a good substrate of CYP2C9. | |||
TN2233 | Spathulenol | Antioxidant , Antifungal | |
Spathulenol is a natural ingredient from Aristolochia yunnanensis that has anti-inflammatory, antioxidant, anti-proliferation, anti-ulcer and anti-mycobacterium activities. Spathulenol showed significant antioxidant acti... | |||
T12830 | Sapienic acid sodium | Antibacterial | |
Sapienic acid sodium is a fatty acid commonly. It has variable antimicrobial activities against Gram-positive and Gram-negative bacteria found on the skin and in the oral cavity. | |||
T3747 | Syringaldehyde | Syringic aldehyde,Springaldehyde | COX |
syringaldehyde is a polyphenolic compound belonging to the group of flavonoids and is found in different plant species like Manihot esculenta and Magnolia officinalis. Syringaldehyde moderately inhibits COX-2 activity wi... | |||
T2785 | 4-Methylherniarin | 7-Methoxy-4-methylcoumarin | Others , Antibacterial |
4-Methylherniarin (7-Methoxy-4-methylcoumarin) is a coumarin derivative and fluorescent label, it displays good activity against B. subtilis. | |||
T2989 | 4-Hydroxybenzoic acid | p-hydroxybenzoic acid,para-Hydroxybenzoic acid,PHBA,4-hydroxybenzoate | Endogenous Metabolite , Antibacterial |
4-Hydroxybenzoic acid (4-hydroxybenzoate) is a monohydroxybenzoic acid, a phenolic derivative of benzoic acid. It is a white crystalline solid that is slightly soluble in water and chloroform but more soluble in polar or... | |||
T4S1718 | Punicalin | HBV , HIV Protease | |
Punicalin exerts anti-inflammatory, antioxidative, and anti-hepatotoxic activities, it shows inhibitory activity on HIV-1 reverse transcriptase in a dose-dependent manner, with an IC50 of 0.11 microg/ml (0.14 microM). | |||
TN1600 | Eclalbasaponin I | Others | |
Eclalbasaponin I has anti-oxidative, and antitumor activities, it reduces oxidative stress-induced neural cell death by autophagy activation, it can dose-dependently inhibit the proliferation of hepatoma cell smmc-7721 w... | |||
TN1772 | Isoastilbin | Anti-infection , Tyrosinase , Antibacterial | |
Isoastilbin is a dihydroflavonol glycoside compound in Rhizoma Smilacis glabrae and Astragalus membranaceus. Isoastilbin inhibits glucosyltransferase (GTase) with an IC50 value of 54.3 μg/mL, Isoastilbin has anti-acne an... | |||
TN6930 | 5-Desmethylsinensetin | Others | |
5-Desmethylsinensetin is a natural product. | |||
T3868 | Agnuside | chasteberry oil | COX , Prostaglandin Receptor , P-gp |
Agnuside (chasteberry oil) inhibits COX-2 (IC50: 0.026 mg/ml) but exhibits less than 10% inhibition of COX-1 at this concentration. It also inhibits 46.3, 66.8, and 82.1% of P-glycoprotein (P-gp) ATPase activity at conce... | |||
TN2083 | Pinostrobin chalcone | ||
Pinostrobin chalcone, a chalcone analog isolated from the leguminous plant, Mucuna pruriens, exhibits anticancer activity with an IC50 value of 20.42±2.23 μg/mL against MDA-MB-231 and 22.51±0.42 μg/mL against the HT-29 c... | |||
T1506 | Vidarabine | Adenine Arabinoside,9-β-D-Arabinofuranosyladenine,Vira-A,Arabinosyladenine,Ara-A | Nucleoside Antimetabolite/Analog , Tyrosine Kinases , DNA/RNA Synthesis , Antibiotic , HSV |
Vidarabine (Adenine Arabinoside) is a nucleoside antibiotic isolated from Streptomyces antibioticus. It has some antineoplastic properties and has broad spectrum activity against DNA viruses in cell cultures and signific... | |||
T37267 | Pachybasin | Antibacterial | |
Pachybasin is an anthraquinone fungal metabolite. Pachybasin shows antimicrobial activities against E. coli, B. subtilis, M. luteus, S. cerevisiae, C. albicans, A. niger, and A. flavus, with MIC values of 64.0 μg/mL, and... | |||
TN1788 | Isookanin | Amylase | |
Isookanin shows strong diphenyl(2,4,6-trinitrophenyl)iminoazanium (DPPH) radical-scavenging activity with the IC50 value of 7.9 ± 0.53 μM. Isookanin is a potent inhibitor of α-amylase (IC50=0.447 mg/ml). | |||
T3S1960 | Kakuol | Antifungal | |
1. Kakuol has antifungal activity, it can completely inhibit the mycelial growth of Botrytis cinerea Pers ex Fr and Cladosporium cucumerinum Ellis & Arthur at 5 microg ml(-1) and 3 microg ml(-1), respectively. 2. kakuol ... | |||
T8185 | (+)-Viroallosecurinine | Viroallosecurinine | Antibacterial |
(+)-Viroallosecurinine (Viroallosecurinine) is a natural alkaloid with antibacterial activity. It exhibits a MIC of 0.48 μg/mL for Ps. Aeruginosa and Staph. aureus. | |||
T2826 | Asaraldehyde | Asarylaldehyde,2,4,5-trimethoxy-Benzaldehyde,Asaronaldehyde | COX |
Asaraldehyde (2,4,5-trimethoxy-Benzaldehyde), a natural COX-2 inhibitor, exhibits 17-fold selectivity than COX-1. | |||
TN2010 | Ombuin | Antibacterial | |
Ombuin has anti-inflammary activity, it inhibits some macrophage functions involved in the inflammatory process. | |||
T38375 | Pseudane IX | 2-nonyl-4-hydroxyquinoline,2-nonyl-1H-quinolin-4-one,2-nonyl-4(1h)-quinolone | HCV Protease |
Pseudane IX (2-nonyl-1H-quinolin-4-one) reduces infection of Huh 7.5 cells by hepatitis C virus (HCV) with an IC50 of 1.4 μg/ml. | |||
T2S1682 | Pinocembrin 7-O-[3''-O-galloyl-4'',6''-hexahydroxydiphenoyl]-β-D-glucoside | Pinocembrin 7-O-(3''-galloyl-4'',6''-(S)-hexahydroxydiphenoyl)-beta-D-glucose,pinocembrin-7-o-3-o-galloyl-4-6-hexahydroxydiphenoyl-beta-d-glucoside | Amylase |
Pinocembrin 7-O-[3''-O-galloyl-4'',6''-hexahydroxydiphenoyl]-β-D-glucoside can moderately inhibit α-amylase activity, with the IC50 value of 0.03 umol/ml. | |||
T3235 | Rebaudioside A | Reb-A 97,Reb A,Stevioside A3,Glycoside A3 | Endogenous Metabolite , Glucosidase |
Rebaudioside A (Reb A) is a novel agent of glycoside clathration of pharmacons, acts as α-glucosidase inhibitor. | |||
TN1019 | Beta-mangostin | β-Mangostin | Apoptosis , Antibacterial , Parasite |
Beta-mangostin (β-Mangostin) is a xanthone compound with antibacterial and antimalarial activities. Beta-mangostin present in Cratoxylum arborescens and exhibits antimycobacterial activity against Mycobacterium tuberculo... | |||
TN5503 | Linaroside | Antibacterial | |
Linaroside exhibited 30% inhibition for antimycobacterial activity against Mycobacterium tuberculosis, strain H(37)Rv at 6.25 microg mL(-1) concentration. | |||
TN3048 | 4-Methoxycinnamaldehyde | p-Methoxycinnamaldehyde | RSV |
4-Methoxycinnamaldehyde (p-Methoxycinnamaldehyde) is an active ingredient of Agastache rugosa.4-Methoxycinnamaldehyde has cytoprotective activity against respiratory syncytial virus (RSV) in human laryngeal carcinoma cel... | |||
TN1440 | Beta-Hydroxyisovalerylshikonin | EGFR , Tyrosine Kinases , Prostaglandin Receptor , Src , AMPK , Fatty Acid Synthase | |
Beta-Hydroxyisovalerylshikonin is an inhibitor of protein-tyrosine kinases such as v-Src and EGFR, and has been shown to induce apoptosis in several human tumor cell lines. Beta-Hydroxyisovalerylshikonin significantly de... | |||
TN2281 | Sinapaldehyde | trans-3,5-Dimethoxy-4-hydroxy cinnamaldehyde | Antibacterial |
Sinapaldehyde (trans-3,5-Dimethoxy-4-hydroxy cinnamaldehyde) is a natural product. Sinapaldehyde exhibits moderate antibacterial against Methicillin resistant S. aureus (MRSA) and E. coli with MIC values of 128 and 128 μ... | |||
TN2283 | Tripterifordin | HIV Protease | |
Tripterifordin shows anti-HIV replication activity in H9 lymphocyte cells with an EC50 of 1 microgram/ml. | |||
T35673 | Stictic Acid | Scopularic acid | Others |
Stictic Acid (Scopularic acid) is isolated from a Sumatran lichen Stereocaulon montagneanum and inhibits the growth of HT-29 human colon adenocarcinoma cells with an IC50 of 29.29 μg/ml. | |||
T6S0214 | Dl-Maackiain | (+)-Maackiain,Demethylpterocarpin | Apoptosis , Parasite |
1. dl-Maackiain (Demethylpterocarpin) induces apoptosis and growth suppression 2. MAK1 is the second functional gene cloned from Maackiain detoxification. | |||
TN2898 | Kaempferol-7,4'-dimethyl ether | 3,5-Dihydroxy-4',7-dimethoxyflavone | Antioxidant , Antifection |
Kaempferol-7,4'-dimethyl ether is isolated from the rhizomes of Zingiber phillipseae and exhibits antioxidant activity against S. aureus and E. coli with MICs at 200 and 225 μg/ml, respectively. | |||
T5S0543 | Isocurcumenol | Apoptosis , Estrogen Receptor/ERR , Reductase | |
1. Isocurcumenol inhibits 5α-reductase which converts testosterone to dihydrotestosterone (DHT). | |||
T2S0493 | Isoeugenol | 4-Propenylguaiacol,2-Methoxy-4-propenylphenol | Antibacterial |
Isoeugenol (4-Propenylguaiacol), an essential oil constituent of nutmeg, clove, and cinnamon, shows antimicrobial activity. | |||
TN1839 | Kumatakenin | Jaranol,Kaempferol 3,7-O-dimethyl ether | Apoptosis , Anti-infection |
Kumatakenin can suppress >80% of the SOS-inducing activity of Trp-P-1 at <0.06 micromol/mL. | |||
T67670 | 4-Ethylbenzaldehyde | Endogenous Metabolite | |
4-Ethylbenzaldehyde is a RIFM flavor present in naturally fermented tilapia sausage and soybean plants.4-Ethylbenzaldehyde shows nematicidal activity at 250 g/ml and can be used as a novel nematicide. | |||
TN1474 | Caulilexin C | Others , Antifungal | |
Caulilexin C shows inhibitory activity on human Acyl CoA: cholesterol transferase I (hACATI) and on human Acyl CoA: cholesterol transferase 2 (hACAT2) at 100 mug/ml. | |||
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Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-00939 | Thrombopoietin Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Thrombopoietin (TPO or THPO), also known as myeloproliferative leukemia virus ligand (c-Mpl), is a hematopoietic growth factor belonging to the EPO/TPO family. The thrombopoietin protein is produced mainly by the liver a... | |||
TMPY-03802 | IL-17F Protein, Human, Recombinant (aa 31-163) | Human | E. coli |
Interleukin-17F (IL-17F) is a cytokine that shares sequence similarity with IL17. The most notable role of IL-17 is its involvement in inducing and mediating proinflammatory responses. IL-17 is commonly associated with a... | |||
TMPY-04201 | Thrombopoietin Protein, Human, Recombinant (hFc) | Human | HEK293 |
Thrombopoietin (TPO or THPO), also known as myeloproliferative leukemia virus ligand (c-Mpl), is a hematopoietic growth factor belonging to the EPO/TPO family. The thrombopoietin protein is produced mainly by the liver a... | |||
TMPY-01898 | IL-17F Protein, Human, Recombinant (aa 31-163, His) | Human | HEK293 |
Interleukin-17F (IL-17F) is a cytokine that shares sequence similarity with IL17. The most notable role of IL-17 is its involvement in inducing and mediating proinflammatory responses. IL-17 is commonly associated with a... | |||
TMPY-05461 | IL-17F Protein, Human, Recombinant (His), Biotinylated | Human | HEK293 |
Interleukin-17F (IL-17F) is a cytokine that shares sequence similarity with IL17. The most notable role of IL-17 is its involvement in inducing and mediating proinflammatory responses. IL-17 is commonly associated with a... | |||
TMPJ-00633 | IL-17F Protein, Cynomolgus, Recombinant (His) | Cynomolgus | Human Cells |
Interleukin-17F (IL-17F) exists in a disulfide-linked heterodimer that belongs to the IL-17 family. IL-17F is expressed in activated, but not resting, CD4+ T-cells and activated monocytes. IL-17F has been shown to stimul... | |||
TMPJ-00573 | IL-17F Protein, Human, Recombinant (His) | Human | Human Cells |
Interleukin-17F (IL-17F) exists in a disulfide-linked heterodimer that belongs to the IL-17 family. IL-17F is expressed in activated, but not resting, CD4+ T-cells and activated monocytes. IL-17F has been shown to stimul... | |||
TMPK-00116 | NKp80/KLRF1 Protein, Human, Recombinant (hFc) | Human | HEK293 |
NKp80, an activating homodimeric C-type lectin-like receptor (CTLR), is expressed on essentially all human natural killer (NK) cells and stimulates their cytotoxicity and cytokine release. | |||
TMPK-00042 | IL-17F Protein, Mouse, Recombinant (His & Avi), Biotinylated | Mouse | HEK293 |
The Interleukin 17 (IL-17) family proteins, comprising six members (IL-17A through IL-17F), are secreted, structurally related proteins that share a conserved cystine-knot fold near the C-terminus, but have considerable ... | |||
TMPK-00041 | IL-17F Protein, Mouse, Recombinant (His & Avi) | Mouse | HEK293 |
The Interleukin 17 (IL-17) family proteins, comprising six members (IL-17A through IL-17F), are secreted, structurally related proteins that share a conserved cystine-knot fold near the C-terminus, but have considerable ... | |||
TMPK-00046 | IL-17F Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 |
The Interleukin 17 (IL-17) family proteins, comprising six members (IL-17A through IL-17F), are secreted, structurally related proteins that share a conserved cystine-knot fold near the C-terminus, but have considerable ... | |||
TMPJ-00046 | IL-17F Protein, Human, Recombinant | Human | E. coli |
Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. Today, IL-17 represents a family of structurally relate... | |||
TMPY-04118 | Livin/BIRC7 Protein, Human, Recombinant (His) | Human | E. coli |
BIRC7, a new member of inhibitor of the apoptosis protein family, is expressed in fetal tissues and most solid tumors in humans. BIRC7/livin expression is a novel prognostic marker in adult acute leukemia. Livin/BIRC7 is... | |||
TMPK-00874 | Thyroid Peroxidase Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Thyroid peroxidase, also called thyroperoxidase (TPO) or iodide peroxidase that encodes a 933 amino-acid residue (aa) molecule with a single membrane-spanning region. Thyroid peroxidase plays a key role in thyroid hormon... | |||
TMPY-01648 | TREML2 Protein, Human, Recombinant (His) | Human | HEK293 |
Trem-like transcript 2 protein, also known as Triggering receptor expressed on myeloid cells-like protein 2, TREML2 and TLT2, is a single-pass type I membrane protein that contains one Ig-like V-type (immunoglobulin-like... | |||
TMPH-01807 | OLFML2B Protein, Human, Recombinant (His & Myc) | Human | HEK293 |
OLFML2B Protein, Human, Recombinant (His & Myc) is expressed in HEK293 with N-terminal 10xHis tag and C-terminal Myc tag. The predicted molecular weight is 86.6 kDa. Accession number: Q68BL8 | |||
TMPK-01505 | HLA-A*02:01&B2M&HPV16 E7 (YMLDLQPET) Monomer Protein, Human, MHC (His & Avi), Biotinylated | Human | HEK293 |
HPV16 E7 protein, one of the primary target proteins in molecular targeted therapy for HPV-induced cervical cancer. The affitoxin, ZHPV16E7 affitoxin384 was generated by fusing the modified Pseudomonas Exotoxin A (PE38KD... | |||
TMPK-01480 | HLA-A*02:01&B2M&Survivin (LMLGEFLKL) Monomer Protein, Human, MHC (His & Avi), Biotinylated | Human | HEK293 |
Survivin (also known as BIRC5) is an evolutionarily conserved eukaryotic protein that is essential for cell division and can inhibit cell death. Normally it is only expressed in actively proliferating cells, but is upreg... | |||
TMPK-01517 | HLA-A*02:01&B2M&Survivin (LMLGEFLKL) Monomer Protein, Human, MHC (His & Avi) | Human | HEK293 |
Survivin (also known as BIRC5) is an evolutionarily conserved eukaryotic protein that is essential for cell division and can inhibit cell death. Normally it is only expressed in actively proliferating cells, but is upreg... | |||
TMPY-01953 | CALML5 Protein, Human, Recombinant (His & GST) | Human | E. coli |
Calmodulin-like protein 5, also known as Calmodulin-like skin protein, CALML5 and CLSP, is a protein which contains fourEF-hand domains. CALML5 / CLSP is particularly abundant in the epidermis where its expression is ... | |||
TMPY-01164 | JAML Protein, Human, Recombinant (His) | Human | HEK293 |
Junctional adhesion molecules (JAMs) are endothelial and epithelial adhesion molecules involved in the recruitment of circulating leukocytes to inflammatory sites. JAML (Junctional adhesion molecule-like), also known as ... | |||
TMPY-04733 | OPCML Protein, Rat, Recombinant (hFc) | Rat | HEK293 |
Opioid-binding Cell Adhesion Molecule (OBCAM), also known as OPCML, is a GPI-anchored cell adhesion molecule in the plasma membrane. This neuron-specific protein consists of three immunoglobulin (Ig)-like domains anchore... | |||
TMPK-00620 | TLT-1/TREML1 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
Triggering receptor expressed on myeloid cells (TREM)-like transcript-1 (TLT-1) is an immunoreceptor tyrosine-based inhibitory motif (ITIM)-baring TREM family protein. Triggering receptor expressed on myeloid cells (TREM... | |||
TMPH-01694 | MLKL Protein, Human, Recombinant (E. coli, His) | Human | E. coli |
Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Does not have protein kinase activity. Activated following phosphorylation by RIPK3, leading to homotrimerization, localizat... | |||
TMPH-02855 | PML Protein, Mouse, Recombinant (His & Myc) | Mouse | E. coli |
Functions via its association with PML-nuclear bodies (PML-NBs) in a wide range of important cellular processes, including tumor suppression, transcriptional regulation, apoptosis, senescence, DNA damage response, and vi... | |||
TMPH-01949 | PML Protein, Human, Recombinant (His & Myc) | Human | Baculovirus |
PML Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus. | |||
TMPH-02465 | Moloney murine leukemia virus (MoMLV) (isolate Shinnick) Gag polyprotein (GST) | MoMLV | E. coli |
Plays a role in budding and is processed by the viral protease during virion maturation outside the cell. During budding, it recruits, in a PPXY-dependent or independent manner, Nedd4-like ubiquitin ligases that conjugat... | |||
TMPK-01504 | HLA-A*02:01&B2M&HPV16 E7 (YMLDLQPET) Tetramer Protein, Human, MHC (His & Avi) | Human | HEK293 |
HPV16 E7 protein, one of the primary target proteins in molecular targeted therapy for HPV-induced cervical cancer. The affitoxin, ZHPV16E7 affitoxin384 was generated by fusing the modified Pseudomonas Exotoxin A (PE38KD... | |||
TMPK-01506 | HLA-A*02:01&B2M&HPV16 E7 (YMLDLQPET) Monomer Protein, Human, MHC (His & Avi) | Human | HEK293 |
HPV16 E7 protein, one of the primary target proteins in molecular targeted therapy for HPV-induced cervical cancer. The affitoxin, ZHPV16E7 affitoxin384 was generated by fusing the modified Pseudomonas Exotoxin A (PE38KD... | |||
TMPJ-00589 | TREML2 Protein, Human, Recombinant (hFc) | Human | Human Cells |
Trem-like transcript 2 protein (TLT2), also known as Triggering receptor expressed on myeloid cells-like protein 2, TLT2 and C6orf76, is single-pass type I membrane protein. TREML2 contains one Ig-like V-type domain, whi... | |||
TMPJ-01144 | TREML2 Protein, Mouse, Recombinant (His) | Mouse | Human Cells |
Trem-like transcript 2 protein (TLT2), also known as Triggering receptor expressed on myeloid cells-like protein 2, TLT2 and C6orf76, is single-pass type I membrane protein. TREML2 contains one Ig-like V-type domain, whi... | |||
TMPJ-00193 | TREML1 Protein, Human, Recombinant (hFc) | Human | Human Cells |
Triggering Receptor Expressed on Myeloid Cells-Like Protein 1 (TREML1) is a single-pass type I membrane protein. TREML1 precursor contains a 15 amino acid signal peptide, a 147 amino acid extracellular domain with an Ig-... | |||
TMPY-00893 | OPCML Protein, Human, Recombinant (His) | Human | HEK293 |
Opioid-binding Cell Adhesion Molecule (OBCAM), also known as OPCML, is a GPI-anchored cell adhesion molecule in the plasma membrane. This neuron-specific protein consists of three immunoglobulin (Ig)-like domains anchore... | |||
TMPY-00224 | JAML Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
Junctional adhesion molecules (JAMs) are endothelial and epithelial adhesion molecules involved in the recruitment of circulating leukocytes to inflammatory sites. JAML (Junctional adhesion molecule-like), also known as ... | |||
TMPY-04093 | JAML Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Junctional adhesion molecules (JAMs) are endothelial and epithelial adhesion molecules involved in the recruitment of circulating leukocytes to inflammatory sites. JAML (Junctional adhesion molecule-like), also known as ... | |||
TMPH-00379 | MLCK Protein, Chicken, Recombinant (His & Myc & SUMO) | Chicken | E. coli |
Phosphorylates a specific serine in the N-terminus of a myosin light chain, which leads to the formation of calmodulin/MLCK signal transduction complexes which allow selective transduction of calcium signals. | |||
TMPH-01950 | PML Protein, Human, Recombinant (His) | Human | E. coli |
PML Protein, Human, Recombinant (His) is expressed in E. coli. | |||
TMPK-01516 | HLA-A*02:01&B2M&Survivin (LMLGEFLKL) Tetramer Protein, Human, MHC (His & Avi) | Human | HEK293 |
Survivin (also known as BIRC5) is an evolutionarily conserved eukaryotic protein that is essential for cell division and can inhibit cell death. Normally it is only expressed in actively proliferating cells, but is upreg... | |||
TMPH-01653 | MLANA Protein, Human, Recombinant (His) | Human | Yeast |
Involved in melanosome biogenesis by ensuring the stability of GPR143. Plays a vital role in the expression, stability, trafficking, and processing of melanocyte protein PMEL, which is critical to the formation of stage ... | |||
TMPH-01634 | MLYCD Protein, Human, Recombinant (His & Myc) | Human | E. coli |
Catalyzes the conversion of malonyl-CoA to acetyl-CoA. In the fatty acid biosynthesis MCD selectively removes malonyl-CoA and thus assures that methyl-malonyl-CoA is the only chain elongating substrate for fatty acid syn... | |||
TMPH-01652 | MLANA Protein, Human, Recombinant (B2M & His) | Human | E. coli |
Involved in melanosome biogenesis by ensuring the stability of GPR143. Plays a vital role in the expression, stability, trafficking, and processing of melanocyte protein PMEL, which is critical to the formation of stage ... | |||
TMPH-03308 | Gremlin-1 Protein, Rat, Recombinant (His & Myc) | Rat | HEK293 |
Gremlin-1 Protein, Rat, Recombinant (His & Myc) is expressed in HEK293. | |||
TMPH-01695 | MLKL Protein, Human, Recombinant (His) | Human | Yeast |
Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Does not have protein kinase activity. Activated following phosphorylation by RIPK3, leading to homotrimerization, localizat... | |||
TMPY-03818 | OPCML Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Opioid-binding Cell Adhesion Molecule (OBCAM), also known as OPCML, is a GPI-anchored cell adhesion molecule in the plasma membrane. This neuron-specific protein consists of three immunoglobulin (Ig)-like domains anchore... | |||
TMPY-02760 | CALML3 Protein, Human, Recombinant (His) | Human | E. coli |
Calmodulin-like protein 3 (CALML3) is similar to that of authentic calmodulin and may actually compete with calmodulin by binding, with different affinity, to cellular substrates. Calmodulin-like protein 3 (CALML3) is a ... | |||
TMPY-01840 | TLT-1/TREML1 Protein, Human, Recombinant (His) | Human | HEK293 |
Trem-like transcript 1 protein, also known as Triggering receptor expressed on myeloid cells-like protein 1, TREML1 and TLT-1, is a cytoplasm and single-pass type I membrane protein. TREML1 / TLT-1 is expressed exclusive... | |||
TMPH-03168 | Exotoxin A Protein, Pseudomonas aeruginosa, Recombinant (His & KSI) | Pseudomonas aeruginosa | E. coli |
An NAD-dependent ADP-ribosyltransferase (ADPRT). Catalyzes the transfer of the ADP ribosyl moiety of oxidized NAD (NAD(+)) onto eukaryotic elongation factor 2 (eEF-2) thus arresting protein synthesis. Has an LD(50) of 65... | |||
TMPH-00715 | Mcr-1 Protein, E. coli, Recombinant (His & SUMO) | E. coli | E. coli |
Probably catalyzes the addition of a phosphoethanolamine moiety to lipid A. Phosphoethanolamine modification of lipid A gives polymyxin resistance.; Confers resistance to polymyxin-type antibiotics; expression of the Mcr... | |||
TMPH-02468 | Mo-CBP3 Protein, Moringa oleifera, Recombinant (GST) | Moringa oleifera | E. coli |
Chitin-binding protein. Has antifungal activity against F.solani, F.oxysporum, C.musae and C.gloesporoides but not against P.oligandrum. Depending on concentration the antifungal activity can be fungistatic or fungicidal... | |||
TMPY-03261 | CNPY2 Protein, Human, Recombinant (His) | Human | HEK293 |
CNPY2 is a novel MIR-interacting protein that enhances neurite outgrowth and increases myosin regulatory light chain. CNPY2 enhances migration of C6 glioma cells through phosphorylation of the myosin regulatory light cha... | |||
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