Powder: -20°C for 3 years | In solvent: -80°C for 1 year
ML380 is a highly potent and the first CNS penetrant M5 positive allosteric modulator (PAM).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
2 mg | In stock | $ 42.00 | |
5 mg | In stock | $ 68.00 | |
10 mg | In stock | $ 122.00 | |
25 mg | In stock | $ 198.00 | |
50 mg | In stock | $ 372.00 | |
100 mg | In stock | $ 556.00 | |
500 mg | In stock | $ 1,220.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 75.00 |
Description | ML380 is a highly potent and the first CNS penetrant M5 positive allosteric modulator (PAM). |
Targets&IC50 | M5 mAChR (human):190 nM, M5 mAChR (rat):610 nM |
Synonyms | ML 380, ML-380 |
Molecular Weight | 494.53 |
Formula | C23H25F3N4O3S |
CAS No. | 1627138-52-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 90 mg/mL (181.99 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
ML380 1627138-52-6 Neuroscience AChR positive ML 380 Muscarinic acetylcholine receptor allosteric inhibit ACh ML-380 modulator Inhibitor mAChR PAM inhibitor