Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ascamycin is a 5'-O-sulfonamide ribonucleoside antibiotic produced by Streptomyces spp. It shows selective antibacterial activity against Xanthomonas species and inhibits Xanthomonas citri, Xanthomonas oryzae and phage with MIC values of 0.4 μg/mL, 12.5 μg/mL and 12.5 μg/mL respectively.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 350.00 | |
5 mg | In stock | $ 828.00 | |
10 mg | In stock | $ 1,130.00 | |
25 mg | In stock | $ 1,590.00 | |
50 mg | In stock | $ 1,980.00 | |
100 mg | In stock | $ 2,500.00 | |
500 mg | In stock | $ 4,900.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 786.00 |
Description | Ascamycin is a 5'-O-sulfonamide ribonucleoside antibiotic produced by Streptomyces spp. It shows selective antibacterial activity against Xanthomonas species and inhibits Xanthomonas citri, Xanthomonas oryzae and phage with MIC values of 0.4 μg/mL, 12.5 μg/mL and 12.5 μg/mL respectively. |
Targets&IC50 | Mycobacterium phlei:12.5 μg/ml, Xanthomonas oryzae:12.5 μg/ml, Xanthomonas citri:(MIC)0.4 μg/ml, Xanthomonas citri:0.4 μg/ml(MIC), Xanthomonas oryzae:12.5 μg/ml(MIC), Mycobacterium phlei:12.5 μg/ml(MIC) |
In vitro |
Ascamycin has a selective antibacterial activity against Xanthomonas species and it has C2-chloroadenine as the base on C-1' which lacks the chlorine.[1] Xanthomonas citri is susceptible to Ascamycin by virtue of the Ascamycin-dealanylating enzyme on the cell surface, When Ascamycin is dealanylated, Dealanylascamycin shows a broad antibacterial activity against various Gram-negative and Gram-positive bacteria.[2] |
Molecular Weight | 451.84 |
Formula | C13H18ClN7O7S |
CAS No. | 91432-48-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 10 mg/mL (22.13 mM)
You can also refer to dose conversion for different animals. More
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Ascamycin 91432-48-3 Cell Cycle/Checkpoint DNA Damage/DNA Repair Microbiology/Virology Others Nucleoside Antimetabolite/Analog Antibacterial Antibiotic inhibitor inhibit