store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Pinostrobin chalcone, a chalcone analog isolated from the leguminous plant, Mucuna pruriens, exhibits anticancer activity with an IC50 value of 20.42±2.23 μg/mL against MDA-MB-231 and 22.51±0.42 μg/mL against the HT-29 colon cancer cell line.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 100.00 | |
5 mg | In stock | $ 241.00 | |
10 mg | In stock | $ 357.00 | |
25 mg | In stock | $ 589.00 | |
50 mg | In stock | $ 858.00 | |
100 mg | In stock | $ 1,180.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 397.00 |
Description | Pinostrobin chalcone, a chalcone analog isolated from the leguminous plant, Mucuna pruriens, exhibits anticancer activity with an IC50 value of 20.42±2.23 μg/mL against MDA-MB-231 and 22.51±0.42 μg/mL against the HT-29 colon cancer cell line. |
In vitro | Pinostrobin chalcone (30 μM; 3T3-L1 cells) was a more potent inhibitor of triglyceride accumulation than the positive control berberine. Gene expression studies revealed that treatment of 3T3-L1 cells with Pinostrobin chalcone lowers the expression levels of CCAAT/enhancer-binding protein α± and peroxisome proliferator activator γ2 during adipogenesis without affecting cell viability. Treatment of 3T3-L1 cells with Pinostrobin chalcone reduced the expression levels of mRNAs encoding sterol regulatory element-binding protein 1c and several lipogenic enzymes, including fatty acid synthase and stearoyl CoA desaturase-1.[1] |
Molecular Weight | 270.28 |
Formula | C16H14O4 |
CAS No. | 18956-15-5 |
store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 90.0 mg/mL (333.0 mM), Sonification is recommended.
You can also refer to dose conversion for different animals. More
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Pinostrobin chalcone 18956-15-5 inhibitor inhibit