Search Result

Search Results for " 干细胞 "

Targets

223

Compounds

Natural Products

Libraries

Cat No.	Product Name	Synonyms	Targets
T13613	ChX710		STING
	ChX710 activates the type I interferon response to cytosolic DNA by priming specific Interferon-Stimulated Genes (ISGs), inducing the ISRE promoter sequence, and facilitating the phosphorylation of Interferon Regulatory ...		STING
T2102	FH1	BRD-K4477,NSC 12407	Others
	FH1 (NSC-12407) (BRD-K4477), a small molecule, enhances the functions of hepatocytes and promotes differentiation hepatocytes derived by iPS.		Others
T40222	FTO-IN-3		Others
	FTO-IN-3 is a FTO inhibitor. FTO-IN-3 impairs self-renewal in glioblastoma stem cells.		Others
T2052	KY02111		Wnt/beta-catenin
	KY02111 facilitates differentiation of hPSCs to cardiomyocytes by inhibiting Wnt signaling, maybe affect downstream of GSK3β and APC.		Wnt/beta-catenin
T3218	Napabucasin	BBI608	STAT
	Napabucasin (BBI608) is an orally available Stat3 and Y cell stemness inhibitor.		STAT
T8987	Epiblastin A		Casein Kinase
	Epiblastin A is an inhibitor of Casein Kinase 1 (CK1). Epiblastin A engages CK1 isoenzymes in cell lysate and induces efficient conversion of epiblast stem cells (EpiSCs) into embryonic stem cells (cESCs).		Casein Kinase
T0640	Benzyl butyl phthalate	BBP,1,2-benzenedicarboxylic acid,butyl phenylmethyl ester,Butyl benzyl phthalate	Others , Aryl Hydrocarbon Receptor
	Benzyl butyl phthalate (1,2-benzenedicarboxylic acid) is used as a plasticizer for PVC.		Others , Aryl Hydrocarbon Receptor
T8786	VUT-MK142		Others
	VUT-MK142 is a new cardiomyogenic small molecule promoting the differentiation of pre-cardiac mesoderm into cardiomyocytes,which may be useful to differentiate stem cells into cardiomyocytes for cardiac repair.		Others
T0838	Triclabendazole	CGA89317	Microtubule Associated , Parasite
	Triclabendazole (CGA89317) has been used in trials studying Parasitic Disease.		Microtubule Associated , Parasite
T33519	MTOB	α-keto-γ-Methylthiobutyric acid,KMBA,MTOB salt,4-methylthio 2-oxobutyric acid	Others
	MTOB (α-keto-γ-Methylthiobutyric acid) is a substrate for c-terminal binding protein (CtBP) that interferes with the carcinogenic activity of CtBP in cell culture and mice. It also actively regulates TCF-4 signaling, lea...		Others
T7491	6-O-Methyl Guanosine		Nucleoside Antimetabolite/Analog
	6-O-Methyl Guanosine inhibit colony-forming ability in a malignant xeroderma pigmentosum cell line.		Nucleoside Antimetabolite/Analog
T3590	NSC23005		CDK
	NSC23005 sodium is a p18INK inhibitor with potently promoted hematopoietic stem cell (HSC) expansion (ED50: 5.21 nM).		CDK
T2431	ID-8	ID8	DYRK
	ID-8, a DYRK inhibitor, sustains embryonic stem cell self-renewal in long-term culture.		DYRK
T2155	Thiazovivin		ROCK
	Thiazovivin, a ROCK inhibitor (IC50: 0.5 μM), increases the survival rate of hESC.		ROCK
T5627	Methoxychlor		Others
	Methoxychlor, an organochlorine pesticide, is thought to be an endocrine disrupter that affects Ca2 homeostasis and cell viability in different cell models.		Others
T4399	ML239	CID-49843203	Others
	ML239 (CID-49843203) is a potent and selective inhibitor of breast cancer stem cells, with an IC50 of 1.16 μM.		Others
T2437	O4I2	O-4I2,O4I2	OCT
	O4I2 is an effective Oct3/4 inducer in various human cell lines including human fibroblasts.		OCT
T37596	Terevalefim		c-Met/HGFR
	Terevalefim (ANG-3777) is an hepatocyte growth factor (HGF) mimetic. Terevalefim selectively activates the c-Met receptor.		c-Met/HGFR
T10343	AOH1160	N-(2-Oxo-2-(2-phenoxyphenylamino)ethyl)-1-naphthamide	Apoptosis , DNA/RNA Synthesis
	AOH1160 is an inhibitor of proliferating cell nuclear antigen (PCNA). AOH1160 induces apoptosis and causes cell-cycle arrest by interfering with DNA replication.		Apoptosis , DNA/RNA Synthesis
T7194	CM-272		Apoptosis , DNA Methyltransferase , Histone Methyltransferase
	CM-272 is a dual G9a/DNA methyltransferases (DNMTs) inhibitor.
T16695	Pyrintegrin		Integrin
	Pyrintegrin is an β1-integrin agonist that promotes embryonic stem cells' survival. Pyrintegrin can be used as a podocyte-protective agent. Pyrintegrin enhances cell-extracellular matrix adhesion-mediated integrin signal...		Integrin
T2003	ISX-9	Isoxazole 9,Isoxazole 9 (ISX-9)	Calcium Channel , Wnt/beta-catenin
	ISX-9 (Isoxazole 9) is necessary to activate neuron-specific genes as neurogenesis inducer.		Calcium Channel , Wnt/beta-catenin
T72482	Dazostinag disodium		STING
	Dazostinag disodium (TAK-676) is a novel stimulator of interferon genes (STING) agonist and immune system modulator with antitumor activity that activates dendritic cells, natural killer cells, and T cells.		STING
T1776	Plerixafor	JM3100,AMD 3100,AMD-3329	Virus Protease , HIV Protease , CXCR
	Plerixafor (AMD-3329), a chemokine receptor antagonist, blocks the binding of stromal cell-derived factor (SDF-1alpha) to the cellular receptor CXCR4.		Virus Protease , HIV Protease , CXCR
T21981	Phthalazinone pyrazole		Aurora Kinase
	Phthalazinone pyrazole is potent, selective, and orally bioavailable inhibitor of Aurora-A kinase. Aurora-A is overexpressed in a variety of tumor types and displays oncogenic activity.		Aurora Kinase
T3995	Amcasertib	BBI503	Stemness kinase
	Amcasertib (BBI503) is an orally administered investigational agent designed to inhibit cancer stem cell pathways via targeting stemness kinases.		Stemness kinase
T16680	PTC-028		Apoptosis , BMI-1
	PTC-028 selectively suppresses cancer cells whereas normal cells remain unaffected. PTC-028 is an orally bioavailable inhibitor of stem cell factor BMI-1 in ovarian cancer. The depletion of BMI-1 by PTC-028 causes caspas...		Apoptosis , BMI-1
TP1828	N-Acetyl-Ser-Asp-Lys-Pro		RAAS
	Acetyl Ser-Asp-Lys-Pro is formed in bone marrow cells by enzymatic processing of thymosin β4. It inhibits the entry of pluripotent hemopoietic stem cells into S-phase of the cell cycle and protects against Ara-C lethalit...		RAAS
T0432	Diclofenac diethylamine		Apoptosis , COX
	Diclofenac Diethylamine, a non-selective COX inhibitor, is utilized as a nonsteroidal anti-inflammatory drug (NSAID).		Apoptosis , COX
T28866	Stemazole		Apoptosis
	Stemazole is a novel small molecule human stem/progenitor cell proliferation activator that promotes the survival of human embryonic stem cells and maintains stemness, and promotes the survival of oligodendrocyte precurs...		Apoptosis
T10745	CDK9-IN-7		CDK
	CDK9-IN-7 is a highly selective and orally active CDK9/cyclin T inhibitor (IC50: 11 nM), which exhibits more potent over other CDKs (CDK4/cyclinD: 148 nM; CDK6/cyclinD: 145 nM).		CDK
T2301	SB 202190	FHPI,SB202190	Apoptosis , p38 MAPK , Autophagy
	SB 202190 (FHPI) is a p38 MAPK inhibitor that inhibits p38α and p38β2 (IC50=50/100 nM) selectively and cell-permeably. SB 202190 has antitumor activity and also induces the differentiation of human embryonic stem cells i...		Apoptosis , p38 MAPK , Autophagy
TP1024	Rusalatide acetate (497221-38-2 free base)	Rusalatide acetate,TP508 amide acetate	Others
	Rusalatide acetate (TP508 amide acetate), a regenerated peptide, alleviates radiation-induced gastrointestinal injury by activating stem cells and protecting recess integrity.		Others
T3589	NSC23005 Sodium		CDK
	NSC23005 sodium is a novel and effective p18 inhibitor (ED50=5.21 nM) in promoting Hematopoietic stem cells (HSCs) expansion in both murine and human models.		CDK
T2019	OAC2		OCT
	OAC2 is an Oct4 activator which activates expression through the Oct4 gene promoter; enhances reprogramming efficiency by increasing the rate of production of induced pluripotent stem cells (iPSCs) from embryonic fibrobl...		OCT
T1748	Kartogenin	KGN	TGF-beta/Smad
	Kartogenin (KGN) is an activator of the smad4/smad5 pathway, and promotes the selective differentiation of multipotent mesenchymal stem cells into chondrocytes.		TGF-beta/Smad
T77635	LSD1-IN-27		Histone Demethylase , PD-1/PD-L1
	LSD1-IN-27 is a potent LSD1 inhibitor with an IC50 value of 13 nM.LSD1-IN-27 inhibited the stemness and migration of gastric cancer cells.LSD1-IN-27 inhibited the expression of PD-L1 in BGC-823 and MFC cells.LSD1-IN-27 p...		Histone Demethylase , PD-1/PD-L1
T5486	RU.521	RU320521	DNA , cGAS
	RU.521 (RU3205217) is a potent dsDNA inhibitor (IC50 : 700 nM), inhibition of the dsDNA pathway by RU.521 requires the presence of cGAS.		DNA , cGAS
T1555	Diclofenac sodium	GP 45840	Apoptosis , COX
	Diclofenac sodium (GP 45840) is a non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.		Apoptosis , COX
T8541	Lenvatinib mesylate	E7080 (mesylate)	VEGFR , FGFR , c-RET , PDGFR , c-Kit
	Lenvatinib mesylate (E7080 (mesylate)) is an oral and multi-targeted inhibitor of VEGFR1-3, FGFR1-4, PDGFR, KIT, and RET, with potent antitumor activities.		VEGFR , FGFR , c-RET , PDGFR , c-Kit
T10904	CWP232228		Wnt/beta-catenin
	CWP232228, a potent and selective Wnt / β-catenin signaling inhibitor, antagonizes the binding of β-catenin to T-cell factor (TCF) in the nucleus. CWP232228 inhibits the formation and metastasis of tumors by inhibiting t...		Wnt/beta-catenin
T22632	TASIN-1	1-[(4-methoxyphenyl)sulfonyl]-4'-methyl-4,1'-bipiperidine	APC
	TASIN-1 is a small molecule inhibitor of mutant adenomatous polyposis coli (APC).		APC
T7545	6-Aminonicotinamide		Others
	6-Aminonicotinamide (6-AN) is a well-established inhibitor of the NADP+-dependent enzyme.		Others
T16528	PI-828	LY 294002, 4gamma-NH2	Casein Kinase , PI3K
	PI-828 is a phosphatidylinositol 3-kinase (PI3K) inhibitor, which is widely used to study the physiological function of PI3K and also promotes stem cell differentiation into mesoderm.		Casein Kinase , PI3K
T0365	Thioridazine hydrochloride	Mellaril,Aldazine	Apoptosis , Potassium Channel , Dopamine Receptor , 5-HT Receptor , Antibacterial , Adrenergic Receptor , Autophagy
	Thioridazine hydrochloride (Mellaril) , an antipsychotic drug, is used in the therapy of psychosis and schizophrenia and shows serotonin antagonism or D4 selectivity.
T2310	CHIR-99021	Laduviglusib,CT99021,CHIR-99021	GSK-3 , Wnt/beta-catenin , Autophagy
	CHIR-99021 (CT99021) is an activator of the Wnt/β-catenin signaling pathway and a GSK-3α/β inhibitor (IC50=10/6.7 nM) with selective and oral activity.CHIR-99021 induces cellular autophagy, which enhances self-renewal in...		GSK-3 , Wnt/beta-catenin , Autophagy
T6711	Tyrphostin AG1296	Tyrphostin AG 1296,AG 1296	Apoptosis , FGFR , FLT , PDGFR , c-Kit
	Tyrphostin AG1296 (Tyrphostin AG 1296) is an inhibitor of PDGFR with IC50 of 0.3-0.5 μM, no activity to EGFR.		Apoptosis , FGFR , FLT , PDGFR , c-Kit
TP1943L1	Pep2-EVKI acetate(1315378-67-6 free base)		GluR
	Pep2-EVKI acetate is a cell-permeable peptide. Pep2-EVKI acetate interferes the interaction between protein interacting with C-kinase (PICK1) and GluR2 AMPA receptor subunits.		GluR
T6470	Diclofenac Potassium	CGP-45840B,Cataflam,Voltfast	Apoptosis , Others , COX
	Diclofenac Potassium (CGP-45840B) is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions.		Apoptosis , Others , COX
T15183	Dynarrestin		Hedgehog/Smoothened
	Dynarrestin is an inhibitor of cytoplasmic dyneins 1 and 2. Dynarrestin suppresses hedgehog (Hh)-dependent proliferation of neuronal precursors and tumor cells. It inhibits dynein 1-driven microtubule gliding in vitro pl...		Hedgehog/Smoothened

Compounds

Synonym: BRD-K4477,NSC 12407

Target: Wnt/beta-catenin

Target: Casein Kinase

Benzyl butyl phthalate

T0640

Synonym: BBP,1,2-benzenedicarboxylic acid,butyl phenylmethyl ester,Butyl benzyl phthalate

Target: Others, Aryl Hydrocarbon Receptor

Target: Microtubule Associated, Parasite

MTOB

T33519

Synonym: α-keto-γ-Methylthiobutyric acid,KMBA,MTOB salt,4-methylthio 2-oxobutyric acid

Target: Nucleoside Antimetabolite/Analog

Synonym: CID-49843203

Synonym: N-(2-Oxo-2-(2-phenoxyphenylamino)ethyl)-1-naphthamide

Target: Apoptosis, DNA/RNA Synthesis

CM-272

T7194

Synonym:

Target: Apoptosis, DNA Methyltransferase, Histone Methyltransferase

Synonym: Isoxazole 9,Isoxazole 9 (ISX-9)

Target: Calcium Channel, Wnt/beta-catenin

Synonym: JM3100,AMD 3100,AMD-3329

Target: Virus Protease, HIV Protease, CXCR

Phthalazinone pyrazole

T21981

Synonym:

Target: Aurora Kinase

Amcasertib

T3995

Synonym: BBI503

Target: Stemness kinase

PTC-028

T16680

Synonym:

Target: Apoptosis, BMI-1

N-Acetyl-Ser-Asp-Lys-Pro

TP1828

Synonym:

Target: RAAS

Diclofenac diethylamine

T0432

Synonym:

Target: Apoptosis, COX

Synonym: FHPI,SB202190

Target: Apoptosis, p38 MAPK, Autophagy

Rusalatide acetate (497221-38-2 free base)

TP1024

Synonym: Rusalatide acetate,TP508 amide acetate

Target: TGF-beta/Smad

LSD1-IN-27

T77635

Synonym:

Target: Histone Demethylase, PD-1/PD-L1

Target: Apoptosis, COX

Lenvatinib mesylate

T8541

Synonym: E7080 (mesylate)

Target: VEGFR, FGFR, c-RET, PDGFR, c-Kit

CWP232228

T10904

Synonym:

Target: Wnt/beta-catenin

TASIN-1

T22632

Synonym: 1-[(4-methoxyphenyl)sulfonyl]-4'-methyl-4,1'-bipiperidine

Synonym: LY 294002, 4gamma-NH2

Target: Casein Kinase, PI3K

Thioridazine hydrochloride

T0365

Synonym: Mellaril,Aldazine

Target: Apoptosis, Potassium Channel, Dopamine Receptor, 5-HT Receptor, Antibacterial, Adrenergic Receptor, Autophagy

CHIR-99021

T2310

Synonym: Laduviglusib,CT99021,CHIR-99021

Target: GSK-3, Wnt/beta-catenin, Autophagy

Tyrphostin AG1296

T6711

Synonym: Tyrphostin AG 1296,AG 1296

Target: Apoptosis, FGFR, FLT, PDGFR, c-Kit

pep2-EVKI acetate(1315378-67-6 free base)

Synonym: CGP-45840B,Cataflam,Voltfast

Target: Apoptosis, Others, COX

Dynarrestin

T15183

Synonym:

Target: Hedgehog/Smoothened

Cat No.	Product Name	Synonyms	Targets
T2S0820	Karanjin		Apoptosis , AMPK
	Karanjin is a flavonoid obtained from the seeds of the karanja tree.Karanjin induces GLUT4 translocation in skeletal muscle cells by increasing AMPK activity. Karanjin can induce cancer cell death through cell cycle arre...		Apoptosis , AMPK
T5646	Cinnamic acid	3-Phenylacrylic acid,β-Phenylacrylic acid	Endogenous Metabolite
	Cinnamic acid (β-Phenylacrylic acid) has potential use in cancer intervention,The concentration causing a 50% reduction of cell proliferation (IC50) ranged from 1 to 4.5 mM in glioblastoma, melanoma, prostate and lung ca...		Endogenous Metabolite
T2598	Thymopentin	TP5	Estrogen/progestogen Receptor , Endogenous Metabolite
	Synthetic pentapeptide corresponding to the amino acids 32-36 of thymopoietin and exhibiting the full biological activity of the natural hormone. Thymopentin (TP5) is an immunomodulator which has been studied for possibl...		Estrogen/progestogen Receptor , Endogenous Metabolite
TMO2681	Xanthosine	9-Beta-D-Ribofuranosylxanthine,Xanthine riboside	Others , Endogenous Metabolite
	Xanthosine (9-Beta-D-Ribofuranosylxanthine) is a xanthine nucleoside that increases the number of mammary stem cells and milk production in goats and cattle.		Others , Endogenous Metabolite
T64911	Blasticidin S HCl		Antibiotic
	Blasticidin S HCl is a peptide-based nucleoside antibiotic (antibiotic) isolated from Streptomyces griseochromogenes that inhibits prokaryotic and eukaryotic protein synthesis by interfering with the formation of peptide...		Antibiotic
T2218	8-Azaguanine	Azaguanine-8,SK 1150,NSC-749,SF-337	Nucleoside Antimetabolite/Analog , Others , Endogenous Metabolite
	8-Azaguanine (SK 1150) is a purine analogue with potential antineoplastic activity.
TN2081	Maohuoside A		MAPK
	Maohuoside A promotes osteogenesis of rat mesenchymal stem cells via BMP and MAPK signaling pathways.		MAPK
T2185	L-Ascorbic acid 2-phosphate trisodium	L-Ascorbic acid 2-phosphate trisodium salt,Sodium L-ascorbyl-2-phosphate,Sodium ascorbyl phosphate,2-Phospho-L-ascorbic acid trisodium salt,Sodium ascorbyl monophosphate	Reactive Oxygen Species , c-Met/HGFR , Endogenous Metabolite
	L-Ascorbic acid 2-phosphate trisodium (Sodium ascorbyl phosphate) is used in biocatalytic dephosphorylation for electric power generation and electrochemical detection assays.
T5084	Xanthosine dihydrate		Others , Endogenous Metabolite
	Xanthosine is produced by guanine-free mutants of bacteria e.g. Bacillus subtilis, Aerobacter aerogenes. Xanthosine monophosphate is an intermediate in purine metabolism, formed from IMP, and forming GMP.		Others , Endogenous Metabolite
T1270	Vincristine sulfate	Leurocristine,22-Oxovincaleukoblastine sulfate,Leurocristine sulfate	Apoptosis , Microtubule Associated
	Vincristine sulfate (Leurocristine sulfate) binds irreversibly to microtubules and spindle proteins in S phase and interferes the formation of the mitotic spindle.		Apoptosis , Microtubule Associated
T64353	4-tert-Octylphenol		Endogenous Metabolite
	4-tert-Octylphenol, an endocrine-disrupting chemical with estrogenic properties, notably induces apoptosis in offspring mouse brain neuronal progenitor cells. This compound decreases levels of bromodeoxyuridine (BrdU), m...		Endogenous Metabolite
TN6982	Diethyl phthalate	1,2-diethyl benzene-1,2-dicarboxylate	Apoptosis
	Diethyl phthalate (1,2-diethyl benzene-1,2-dicarboxylate) is a endocrine disrupter affecting the apoptotic system in PC12 cells. Diethyl phthalate is widely used in many plastics and personal care products.		Apoptosis
PDK0101	4-Methylcinnamic acid		Antifungal
	4-Methylcinnamic acid is a cinnamic acid analog that can be used as an intervention catalyst to overcome antifungal tolerance. 4-Methylcinnamic acid can improve the potency of cell wall-disrupting agents.		Antifungal
TN1674	Garcinone D		Reactive Oxygen Species , Nrf2 , STAT
	Garcinone D shows significant cytotoxicity against the CEM-SS cell line, with IC(50) value of 3.2 microg/ml; it exhibits dose-dependent enzyme-based microsomal aromatase inhibitory activity. Garcinone D inhibits p65 acti...		Reactive Oxygen Species , Nrf2 , STAT
T3916	Ginsenoside F2		Apoptosis , Endogenous Metabolite , Autophagy
	Ginsenoside F2 has antiproliferative activity against breast cancer stem cells (CSCs). It induces apoptosis in breast CSCs by activating the intrinsic apoptotic pathway and mitochondrial dysfunction.		Apoptosis , Endogenous Metabolite , Autophagy
T3S0027	Picropodophyllotoxin	AXL 1717,Picropodophyllin	IGF-1R
	Picropodophyllotoxin (AXL 1717) is a cyclolignan alkaloid found in the mayapple plant family (Podophyllum peltatum), and a small molecule inhibitor of the insulin-like growth factor 1 receptor (IGF1R) with potential anti...		IGF-1R
T2966	Beta-Sitosterol	Cupreol,Beta-Sitosterol,β-Sitosterol,Azuprostat,SKF 14463,22,23-Dihydrostigmasterol,Betaprost	Apoptosis , Lipase , Endogenous Metabolite
	Beta-Sitosterol (SKF 14463) has recently been shown to induce G2/M arrest, endoreduplication, and apoptosis through the Bcl-2 and PI3K/Akt signaling pathways. Beta-Sitosterol (SKF 14463) , a main dietary phytosterol foun...		Apoptosis , Lipase , Endogenous Metabolite
TN6647	4-O-Cinnamoylquinic acid		Prostaglandin Receptor
	4-O-Cinnamoylquinic acid is a small molecule compound extracted from the dried fruits of Casearia grewiifolia, which has an inhibitory effect on prostaglandins and inhibits the production of superoxide anions in human ne...		Prostaglandin Receptor
T3S2312	Poncirin	Isosakuranetin-7-neohesperidoside	Apoptosis , Others
	1. Poncirin (Isosakuranetin-7-neohesperidoside) shows a significant in vitro inhibitory effect on the growth of the human gastric cancer cells, SGC-791, in a dose-dependent manner. 2. Poncirin prevents adipogenesis, enha...		Apoptosis , Others
T8678	Naphthazarin	5,8-Dihydroxy-1,4-naphthoquinone,DHNQ	Apoptosis
	Naphthazarin (5,8-Dihydroxy-1,4-naphthoquinone) is effective by various cellular mechanisms including oxidative stress, activation of mitochondrial apoptosis-inducing factor (AIF), depolymerization of microtubules, inter...		Apoptosis
T1022	Hygromycin B	Hygrovetine	ribosome , Antibacterial , Antibiotic , Antifungal
	Hygromycin B (Hygrovetine) is an aminoglycoside antibiotic that inhibits protein synthesis by interfering with translocation and causing mistranslation of the 70S ribosome. Hygromycin B can be used to screen prokaryotic ...		ribosome , Antibacterial , Antibiotic , Antifungal
TN7036	N-(3-Methoxybenzyl)-(9Z,12Z,15Z)-octadecatrienamide	(9Z,12Z,15Z)-N-[(3-Methoxyphenyl)methyl]-9,12,15-octadecatrienamide,Macamide Impurity 14	Wnt/beta-catenin
	N-(3-Methoxybenzyl)-(9Z,12Z,15Z)-octadecatrienamide (Macamide Impurity 14) induces osteogenic differentiation and subsequent bone formation of mesenchymal stem cells by activating the canonical Wnt/β-catenin signaling pa...		Wnt/beta-catenin
T20643	Cefoxitin	Rephoxitin,Cefoxitinum	Cell wall , Antibacterial , Antibiotic
	Cefoxitin (Rephoxitin) is a broad-spectrum, orally available second-generation cephalosporins antibiotic. Cefoxitin interferes with the synthesis of bacterial cell walls. Its activity profile includes Gram-negative and G...		Cell wall , Antibacterial , Antibiotic
TN1163	2'-Hydroxychalcone		Others
	2'-Hydroxychalcone is a drug synthesis intermediate for the synthesis of flavonoids. 2'-Hydroxychalcone loaded in nanoemulsion showed fungicidal activity against Coccidioides parapsilosis in Danio rerio model.2'-Hydroxyc...		Others
T0906	Salinomycin	Procoxacin	Wnt/beta-catenin , Antibacterial
	Salinomycin (Procoxacin), a polyether potassium ionophore antibiotic, specifically inhibits the growth of gram-positive bacteria. It acts as a potent inhibitor of Wnt/β-catenin signaling, blocking Wnt-induced LRP6 phosph...		Wnt/beta-catenin , Antibacterial
T82310	Glomeratide A
	Glomeratide A, a benzophenone C-glucoside, exhibits hepatoprotective properties and safeguards rat liver epithelial stem-like cells from d-galactosamine-induced hepatotoxicity.
T75661	Thymopentin acetate
	Thymopentin acetate, primarily secreted by the epithelial cells of the thymic cortex and medulla, serves as an effective immunomodulatory agent. It possesses a short plasma half-life of 30 seconds and significantly enhan...
TQ0215	Salinomycin sodium salt	Sodium salinomycin,Salinomycin sodium	Apoptosis , Wnt/beta-catenin , Antibacterial , Antibiotic , Autophagy
	Salinomycin sodium salt (Sodium salinomycin), an antibiotic potassium ionophore, is an effective inhibitor of Wnt/β-catenin signaling.
T13606L	CGAMP disodium
	cGAMP disodium is a cyclic dinucleotide (CDN) found in bacteria that acts as an endogenous second messenger affecting interferon production in response to cytoplasmic DNA. cGAMP disodium cascades signals from type I inte...

Natural Products

Karanjin

T2S0820

Synonym:

Target: Apoptosis, AMPK

Cinnamic acid

T5646

Synonym: 3-Phenylacrylic acid,β-Phenylacrylic acid

Target: Endogenous Metabolite

Thymopentin

T2598

Synonym: TP5

Target: Estrogen/progestogen Receptor, Endogenous Metabolite

Xanthosine

TMO2681

Synonym: 9-Beta-D-Ribofuranosylxanthine,Xanthine riboside

Target: Others, Endogenous Metabolite

Synonym: Azaguanine-8,SK 1150,NSC-749,SF-337

Target: Nucleoside Antimetabolite/Analog, Others, Endogenous Metabolite

L-Ascorbic acid 2-phosphate trisodium

T2185

Synonym: L-Ascorbic acid 2-phosphate trisodium salt,Sodium L-ascorbyl-2-phosphate,Sodium ascorbyl phosphate,2-Phospho-L-ascorbic acid trisodium salt,Sodium ascorbyl monophosphate

Target: Reactive Oxygen Species, c-Met/HGFR, Endogenous Metabolite

Xanthosine dihydrate

T5084

Synonym:

Target: Others, Endogenous Metabolite

Vincristine sulfate

T1270

Synonym: Leurocristine,22-Oxovincaleukoblastine sulfate,Leurocristine sulfate

Target: Apoptosis, Microtubule Associated

4-tert-Octylphenol

T64353

Synonym:

Target: Endogenous Metabolite

Diethyl phthalate

TN6982

Synonym: 1,2-diethyl benzene-1,2-dicarboxylate

Target: Apoptosis

4-Methylcinnamic acid

Target: Reactive Oxygen Species, Nrf2, STAT

Ginsenoside F2

T3916

Synonym:

Target: Apoptosis, Endogenous Metabolite, Autophagy

Picropodophyllotoxin

T3S0027

Synonym: AXL 1717,Picropodophyllin

Target: IGF-1R

Beta-Sitosterol

T2966

Synonym: Cupreol,Beta-Sitosterol,β-Sitosterol,Azuprostat,SKF 14463,22,23-Dihydrostigmasterol,Betaprost

Target: Apoptosis, Lipase, Endogenous Metabolite

4-O-Cinnamoylquinic acid

TN6647

Synonym:

Target: Prostaglandin Receptor

Poncirin

T3S2312

Synonym: Isosakuranetin-7-neohesperidoside

Target: Apoptosis, Others

Naphthazarin

T8678

Synonym: 5,8-Dihydroxy-1,4-naphthoquinone,DHNQ

Target: ribosome, Antibacterial, Antibiotic, Antifungal

N-(3-Methoxybenzyl)-(9Z,12Z,15Z)-octadecatrienamide

TN7036

Synonym: (9Z,12Z,15Z)-N-[(3-Methoxyphenyl)methyl]-9,12,15-octadecatrienamide,Macamide Impurity 14

Target: Wnt/beta-catenin

Cefoxitin

T20643

Synonym: Rephoxitin,Cefoxitinum

Target: Cell wall, Antibacterial, Antibiotic

Target: Wnt/beta-catenin, Antibacterial

Salinomycin sodium salt

TQ0215

Synonym: Sodium salinomycin,Salinomycin sodium

Target: Apoptosis, Wnt/beta-catenin, Antibacterial, Antibiotic, Autophagy

Cat No.	Product Name
L8000	Stem Cell Differentiation Compound Library	1213 compounds
	A unique collection of 1213 stem cell differentiation signaling targeted compounds for high throughput and high content screening;
L1000	Approved Drug Library	2863 compounds
	A unique collection of 2863 approved drugs for high throughput screening (HTS) and high content screening (HCS);
L8100	Cell Cycle Compound Library	695 compounds
	A unique collection of 695 cell cycle related compounds for high throughput screening (HTS) and high content screening (HCS);
L8110	Reprogramming Compound Library	1840 compounds
	A unique collection of 1840 reprogramming signaling pathway-related bioactive small molecule compounds for high-throughput, high-content screening.
L5500	Toxic Compound Library	277 compounds
	A unique collection of 277 toxic substances for high throughput screening (HTS) and high content screening (HCS);
L3600	Cytokine Inhibitor Library	613 compounds
	A unique collection of 613 compounds targeting cytokine signaling for high throughput screening and high content screening for drug discovery;
L4000	Bioactive Compound Library	14590 compounds
	A collection of 14590 small molecule compounds with validated activity for high throughput screening (HTS), high content screening (HCS), cell induction, and target identification;
L4010	Bioactive Compounds Library Max	22706 compounds
	A collection of 22706 bioactive compounds for high-throughput screening, high-content screening, cell induction and target identification.
L1010	FDA-Approved & Pharmacopeia Drug Library	3158 compounds
	3158 compounds from marketed drugs for high throughput screening (HTS) and high content screening (HCS);
L8200	Anti-Aging Compound Library	3324 compounds
	A unique collection of 3324 anti-aging compounds for high throughput screening (HTS) and high content screening (HCS);
L8500	HIF-1 Signaling Pathway Compound Library	1352 compounds
	A unique collection of 1352 HIF-1 related small chemicals can be used for drug discovery in ischemic disease and cancer and related mechanism studies；
L1100	Protease Inhibitor Library	344 compounds
	A unique collection of 344 protease and proteasome inhibitors for research in chemical genomics, and drug screening;
L6740	Anti-Colorectal Cancer Traditional Chinese Medicine Compound Library	386 compounds
	A collection of 386 TCM monomers with anti-colorectal activity. An effective tool for drug development and pharmacological studies.
L7400	Sodium Channel Blocker Library	128 compounds
	A unique collection of 128 sodium channel blockers and agonists for high throughput and high content screening;
L2600	Neuronal Signaling Compound Library	2540 compounds
	A unique collection of 2540 compounds targeting CNS signaling for high throughput screening (HTS) and high content screening (HCS) for new drugs;
L6150	Covalent Natural Product Library	596 compounds
	Detialed biological information and pharmacological information of the products, providing theoretical direction and research basis for screening.
L6000	Natural Product Library for HTS	4320 compounds
	A unique collection of 4320 pure natural products and their derivatives with known biological activity for drug discovery, pharmacological study, stem cell differentiation, fingerprint study and quality research, and can...
L6900	Rare Natural Product Library	180 compounds
	A unique collection of 180 rare natural products, which can be used for high throughput screening (HTS) and high content screening (HCS);
L7110	Anti-Hypertension Compound Library	719 compounds
	719 hypertension-related small molecules for high-throughput and high-content screening.