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ChX710

Catalog No. T13613 CAS 2438721-44-7

ChX710 could prime the type I interferon response to cytosolic <a href="/target/DNA" style="display: inline; color: #c13a36">DNA</a>, which specific cellular Interferon-Stimulated Genes (ISGs), induces the ISRE promoter sequence, and the phosphorylation of Interferon Regulatory Factor (IRF) 3.

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ChX710, CAS 2438721-44-7

Pack Size	Availability	Price/USD
1 mg	In stock	$ 108.00
5 mg	In stock	$ 221.00
10 mg	In stock	$ 329.00
25 mg	In stock	$ 587.00
50 mg	In stock	$ 869.00
100 mg	In stock	$ 1,265.00
200 mg	In stock	$ 1,898.00
500 mg	In stock	$ 3,597.00
1 mL * 10 mM (in DMSO)	In stock	$ 243.00

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Purity: 99.51%

Biological Description

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Description	ChX710 could prime the type I interferon response to cytosolic DNA, which specific cellular Interferon-Stimulated Genes (ISGs), induces the ISRE promoter sequence, and the phosphorylation of Interferon Regulatory Factor (IRF) 3.
In vitro	The treatment of ChX710 efficiently prime the cellular response to DNA transfection via STING as assessed by strong synergistic effects on IFN-β expression at both transcriptional and protein levels.

Molecular Weight	323.39
Formula	C18H21N5O
CAS No.	2438721-44-7

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

DMSO: 20 mg/mL (61.84 mM), Need ultrasonic

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Khiar S, et al. Identification of a small molecule that primes the type I interferon response to cytosolic DNA. Sci Rep. 2017 May 31;7(1):2561.

Related compound libraries

This product is contained In the following compound libraries：

Bioactive Compound Library Bioactive Compounds Library Max Immuno-Oncology Compound Library NO PAINS Compound Library Immunology/Inflammation Compound Library

Related Products

Related compounds with same targets

STING activator Compound 53 SN-008 N-[3-[(4-fluorophenyl)sulfonylamino]-4-methoxyphenyl]-4-phenylbenzamide SN-011 STING-IN-3 STING-IN-2 MSA-2 STING agonist-1

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

ChX710 2438721-44-7 Immunology/Inflammation STING MPYS ERIS ChX 710 TMEM173 Inhibitor inhibit MITA Stimulator of Interferon Genes ChX-710 inhibitor

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