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TargetMol | Compound Library

Covalent Natural Product Library

Catalog No. L6150

Natural products have been proven to demonstrate their success in modulating certain isolated but important targets, such as a range of antimicrobial targets, in particular protein-protein interactions. Therefore, many researchers consider natural products and their derivatives as unique tools for the study and manipulation of protein function.

Covalent compounds, a class of organic small molecules, can interact with specific target proteins and form covalent bonds, resulting in a change in protein conformation that inhibits protein activity. Except for some rare cases, protein modifications by covalent interactions are usually irreversible.

TargetMol Natural Product Covalent Library carefully screens 609 covalent compounds of natural products, which have not only the characteristics of natural products but also the mechanism of action of covalent compounds, and are cost-effective and powerful tools for drug development, pharmacological studies, stem cell differentiation, fingerprinting studies, quality studies and other fields.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L6150

Covalent Natural Product Library

size

  • 1 mg
  • 10 µL x 10 mM (in DMSO)
  • 20 µL x 10 mM (in DMSO)
  • 30 µL x 10 mM (in DMSO)
  • 50 µL x 10 mM (in DMSO)
  • 100 µL x 10 mM (in DMSO)
  • 250 µL x 10 mM (in DMSO)
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Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

Product Description Product Description

  • Detialed biological information and pharmacological information of the products, providing theoretical direction and research basis for screening.
  • Clear source: a selection of known active natural products from animals, plants and microorganisms; specific to plant species, and labeled with accurate English and Latin names that facilitates later verification in your research.
  • Comprehensive information: Detailed descriptions from compound structure to solubility, from signaling pathways and targets to biological activity information.
  • Cost-effective: eliminates expensive natural products with poor drug-forming properties, allowing you to get more high-quality natural products at a lower cost.
  • Highly customizable with free combination according to natural product source, natural product category, research area, drug market status, etc.

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Library Customization | TargetMol Library Composition

Apoptosis
Endogenous Metabolite
Antibacterial
NF-κB
Autophagy
Antibiotic
ROS
Antifungal
Akt
COX
p38 MAPK
Reactive Oxygen Species
Interleukin
Caspase
Parasite
Antioxidant
ERK
Cytochromes P450
Influenza Virus
Nrf2
NO Synthase
PI3K
Calcium Channel
STAT
Dehydrogenase
Microtubule Associated
HIV Protease
MMP
Anti-infection
HIF/HIF Prolyl-Hydroxylase
NOD-like Receptor (NLR)
ATPase
GABA Receptor
TNF
Ferroptosis
JNK
HSV
Cholinesterase (ChE)
DNA/RNA Synthesis
P-gp
Bcl-2 Family
AMPK
SARS-CoV
Tyrosinase
Reductase
Virus Protease
Wnt/beta-catenin
VEGFR
PKC
TRP/TRPV Channel
CDK
Beta Amyloid
Estrogen/progestogen Receptor
PPAR
Glucocorticoid Receptor
Immunology/Inflammation related
Lipoxygenase
Antiviral
Prostaglandin Receptor
ribosome
NOS
Mitophagy
GSK-3
JAK
IL Receptor
Androgen Receptor
TGF-beta/Smad
AChR
Sodium Channel
Proteasome
Estrogen Receptor/ERR
HBV
PARP
Adrenergic Receptor
Drug Metabolite
glycosidase
CaMK
EGFR
HSP
TLR
IκB/IKK
HDAC
Aromatase
Ras
PERK
Progesterone Receptor
PKA
FXR
IAP
PDE
Antifection
Opioid Receptor
Angiotensin-converting Enzyme (ACE)
Epigenetic Reader Domain
mTOR
Lipid
MAPK
Pyroptosis
Potassium Channel
ADC Cytotoxin
Chloride channel
Transferase
Histone Methyltransferase
Src
BACE
RAAS
Phosphatase
Serine Protease
MAO
iGluR
UGT
Gamma-secretase
Glucosidase
Mitochondrial Metabolism
Survivin
Sirtuin
Retinoid Receptor
Phospholipase
HIF
Thrombin
p53
PD-1/PD-L1
Monoamine Oxidase
Mdm2
Proton pump
Transaminase
RAR/RXR
Dopamine Receptor
DNA-PK
HCV Protease
Integrin
YAP
IFNAR
Arrestin
Lipase
Histamine Receptor
Galectin
c-Myc
MRP
Tyrosine Kinases
Serine/threonin kinase
Cysteine Protease
Leukotriene Receptor
RANKL/RANK
Topoisomerase
IRE1
Bcr-Abl
Raf
Glucagon Receptor
NMDAR
P2X Receptor
Monoamine Transporter
Smo
PDGFR
Hedgehog/Smoothened
CXCR
PTEN
Xanthine Oxidase
Cadherin
IGF-1R
Telomerase
OXPHOS
Beta-Secretase
PGE Synthase
Acyltransferase
Free radical scavengers
AIM2
Histone Acetyltransferase
CPT
Casein Kinase
RSV
ATM/ATR
TMV
Reverse Transcriptase
CRISPR/Cas9
FOXO
PLK
MEK
FGFR
Complement System
Platelet aggregation
Syk
NOD
FAK
ROS Kinase
AhR
HER
PKM
S1P Receptor
Vitamin
ADC Linker

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