Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Cefoxitin (Rephoxitin) is a broad-spectrum, orally available second-generation cephalosporins antibiotic. Cefoxitin interferes with the synthesis of bacterial cell walls. Its activity profile includes Gram-negative and Gram-positive bacteria, and is commonly used in abdominal cavity infections, pelvic infections, and certain types of gynecological infections, and is highly effective against anaerobic bacteria.
Pack Size | Availability | Price/USD | Quantity |
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500 mg | In stock | $ 96.00 |
Description | Cefoxitin (Rephoxitin) is a broad-spectrum, orally available second-generation cephalosporins antibiotic. Cefoxitin interferes with the synthesis of bacterial cell walls. Its activity profile includes Gram-negative and Gram-positive bacteria, and is commonly used in abdominal cavity infections, pelvic infections, and certain types of gynecological infections, and is highly effective against anaerobic bacteria. |
Targets&IC50 | PBP2b:0.19 μg/mL, PBP5:0.19 μg/mL, PBP4:0.14 μg/mL, PBP3:1.04 μg/mL, PBP2a:0.72 μg/mL |
In vitro | Cefoxitin demonstrates effective antimicrobial properties against Gram-positive bacteria, with minimum inhibitory concentrations (MICs) spanning from 1-6 μg/mL for various Gram-positive pathogens[1]. Furthermore, at a concentration of 1.25 µM/mL, Cefoxitin exhibits potent bactericidal activity against B. burgdorferi[2]. |
In vivo | Cefoxitin administration at a dose of 20 mg/kg via intraperitoneal injection for 5 consecutive days demonstrates effective eradication of B. burgdorferi in the C3H/HeN mouse model.[2] |
Synonyms | Rephoxitin, Cefoxitinum |
Molecular Weight | 427.45 |
Formula | C16H17N3O7S2 |
CAS No. | 35607-66-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 90.0 mg/mL (210.6 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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Cefoxitin 35607-66-0 Immunology/Inflammation Microbiology/Virology Cell wall Antibiotic Antibacterial Rephoxitin Cefoxitinum inhibitor inhibit