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O4I2

Catalog No. T2437 CAS 165682-93-9

O4I2 is an effective Oct3/4 inducer in various human cell lines including human fibroblasts.

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O4I2, CAS 165682-93-9

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	O4I2 is an effective Oct3/4 inducer in various human cell lines including human fibroblasts.
In vitro	O4I2 activates Oct3/4 expression in HEK293 and embryonal NCCIT cells, and also in Oct-deficient HeLa and terminally differentiated human fibroblasts, and also induces other pluripotency-associated genes such as Lin28 and Nanog. [1]

Molecular Weight	282.74
Formula	C12H11ClN2O2S
CAS No.	165682-93-9

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

Ethanol: 14.1 mg/mL (50 mM)

DMSO: 28.3 mg/mL (100 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Cheng X, et al. J Med Chem. 2015 Aug 13;58(15):5742-5750.

Related compound libraries

This product is contained In the following compound libraries：

Anti-Cancer Compound Library Ion Channel Inhibitor Library Stem Cell Differentiation Compound Library Anti-Aging Compound Library Bioactive Compound Library

Related Products

Related compounds with same targets

Retrorsine 3-O-Methylgallic acid Jatrorrhizine chloride Oct3/4-inducer-1 O4I1 O4I2 OAC1 OAC2

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

O4I2 165682-93-9 离子通道 OCT Oct3/4 iPSCs lin28 pluripotent Slc22a3 activator Rex1 cell inhibit stem Inhibitor 3-10月 O-4I2 nanog sox2 4-10月 POU5F1 inhibitor

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