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Triclabendazole

Triclabendazole
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Purity:98.35%
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Triclabendazole

Catalog No. T0838Cas No. 68786-66-3
Triclabendazole (CGA89317) has been used in trials studying Parasitic Disease.
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Pack SizePriceAvailabilityQuantity
25 mg$44In Stock
50 mg$63In Stock
100 mg$79In Stock
200 mg$102In Stock
500 mg$167In Stock
1 mL x 10 mM (in DMSO)$50In Stock
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Product Introduction

Bioactivity
Description
Triclabendazole (CGA89317) has been used in trials studying Parasitic Disease.
In vitro
Triclabendazole treatment produces percentage decreases of the fluke egg output by 15.3%, 4.3% and 36.6%, respectively, in sheep, dairy cows and heifers, these results indicate the presence of TCBZ-resistant Fasciola hepatica in sheep and cattle on this farm. [1] Triclabendazole sulphoxide (50 mg/mL) results in extensive damage to the tegument of triclabendazole-susceptible F. hepatica, whereas triclabendazole-resistant flukes shows only localized and relatively minor disruption of the tegument covering the spines. [2]
AliasCGA89317
Chemical Properties
Molecular Weight359.66
FormulaC14H9Cl3N2OS
Cas No.68786-66-3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 60 mg/mL (166.82 mM), Sonication is recommended.
H2O: < 1 mg/mL (insoluble or slightly soluble)
Ethanol: < 1 mg/mL (insoluble or slightly soluble)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.7804 mL13.9020 mL27.8040 mL139.0202 mL
5 mM0.5561 mL2.7804 mL5.5608 mL27.8040 mL
10 mM0.2780 mL1.3902 mL2.7804 mL13.9020 mL
20 mM0.1390 mL0.6951 mL1.3902 mL6.9510 mL
50 mM0.0556 mL0.2780 mL0.5561 mL2.7804 mL
100 mM0.0278 mL0.1390 mL0.2780 mL1.3902 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
1 Enter information below:
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