Search Result

Search Results for " il-2 "

179

Compounds

Natural Products

624

Recombinant Proteins

Libraries

Cat No.	Product Name	Synonyms	Targets
T40355	IL-17A modulator-2
	IL-17A modulator-2, exhibits inhibitory properties towards IL-17A, with a pIC50 of 8.3. Its effectiveness lies in attenuating the biological effects associated with IL-17A activity. IL-17A modulator-2 finds utility in th...
T40116	IL-17A inhibitor 2
	IL-17A inhibitor 2 is an IL-17A inhibitor for treating psoriasis, rheumatoid arthritis, and multiple sclerosis.
T62183	IL-2-IN-1
	IL-2-IN-1 is a potent inhibitor of IL-2 (IC50: 1978 nM) and exhibits anti-proliferative effects.
T21629	Loxapine		Dopamine Receptor , 5-HT Receptor
	Loxapine is a D2DR and D4DR inhibitor, serotonergic receptor antagonist and also a dibenzoxazepine anti-psychotic agent,used primarily in the treatment of schizophrenia. The drug is a member of the dibenzoxazepine class ...		Dopamine Receptor , 5-HT Receptor
T9631	IRAK-4 protein kinase inhibitor 2		IRAK
	IRAK-4 protein kinase inhibitor 2 is a potent interleukin-1 receptor-associated kinase-4 (IRAK-4) inhibitor(IC50 = 4 μM).		IRAK
T22338	2,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide	GDC046	Others , JAK
	2,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide (GDC046), a potent lead analog, has good kinase selectivity, physicochemical properties and pharmacokinetic profile.		Others , JAK
T16501	PF-3644022		p38 MAPK , Serine Protease , MAPK
	PF-3644022 is an effective, selective, and ATP-competitive MAPKAPK2 (MK2) inhibitor (IC50: 5.2 nM and a Ki of 3 nM). PF-3644022 potently inhibits TNFα production and has an anti-inflammatory effect. PF-3644022 also inhib...		p38 MAPK , Serine Protease , MAPK
T1412	Loxapine succinate	Daxolin,Loxapac,Cloxazepin,Loxapine succinate salt	Dopamine Receptor , 5-HT Receptor
	Loxapine succinate (Loxapac), a D2DR and D4DR inhibitor, is utilized in schizophrenia.		Dopamine Receptor , 5-HT Receptor
T41302	Itaconate-alkyne	ITalk	Others
	Itaconate-alkyne (ITalk) is a bioorthogonal probe for quantitative and site-specific chemoproteomic profiling of itaconate in inflammatory macrophages and enables biochemical evaluation and proteomic analysis of its dire...		Others
T22330	Fenamic acid	2-Anilinobenzoic acid,Diphenylamine-2-carboxylic acid,2-(Phenylamino)benzoic acid,N-Phenylanthranilic acid	Chloride channel
	Fenamic acid (N-Phenylanthranilic acid) is a chloride channel blocker that causes renal papillary necrosis in rats. Fenamic acid serves as a parent structure for several nonsteroidal anti-inflammatory drugs (NSAIDs), inc...		Chloride channel
T12399	Peldesine	BCX 34	Nucleoside Antimetabolite/Analog , HIV Protease
	Peldesine (BCX 34) is an effective, competitive, reversible, and orally active inhibitor of purine nucleoside phosphorylase. Peldesine inhibits T-cell proliferation with an IC50 of 800 nM. Peldesine can be used in resear...		Nucleoside Antimetabolite/Analog , HIV Protease
T78707	IL-1β-IN-2
	IL-1β-IN-2, a cannabigerol derivative, serves as a potent inhibitor of IL-1β, exhibiting anti-inflammatory and pain-resolving properties [1].
T8867	RO2959 Hydrochloride	RO2959 HCl	IL Receptor , Calcium Channel , Interleukin
	RO2959 Hydrochloride (RO2959 HCl) is a potent and selective inhibitor of CRAC channel(IC50: 402 nM). It is also a potent inhibitor of human IL-2.		IL Receptor , Calcium Channel , Interleukin
T14074	A-770041		Src
	A-770041 is a selective and orally active inhibitor targeting the Src-family kinase, Lck, which plays a crucial role in T-cell signaling. With an IC50 value of 147 nM at 1 mM ATP, A-770041 demonstrates high specificity b...		Src
T6933	Peficitinib	ASP015K,JNJ-54781532	Tyrosine Kinases , JAK
	Peficitinib (ASP015K) (ASP015K, JNJ-54781532) is an orally bioavailable JAK inhibitor. Phase 3.		Tyrosine Kinases , JAK
T12218	NFAT Transcription Factor Regulator-1		IL Receptor
	NFAT Transcription Factor Regulator-1 is an synthesis inhibitor of IL-2 (IC50 of 182 nM).		IL Receptor
T76778	Risankizumab	Risankizumab rzaa,SKYRIZI,ABBV 066,BI-655066	IL Receptor
	Risankizumab (BI 655066) is a humanized IgG monoclonal antibody (Kd <10 pM) targeting the IL-23 p19 subunit. Risankizumab inhibits IL-17 production induced by human IL-23 in mouse splenocytes with an IC50 value of 2 pM.R...		IL Receptor
TP1433	CMD178 TFA		STAT
	CMD178 (TFA) is a lead peptide that consistently reduces the expression of Foxp3 and STAT5 induced by IL-2/s IL-2Rα signaling.		STAT
T73689	Daclizumab	Ro 24-7375,Zenapax	IL Receptor
	Daclizumab (Zenapax) is a humanized monoclonal antibody that specifically inhibits the alpha subunit of IL-2R-HA. Daclizumab (Zenapax) can inhibit the binding of IL-2 and IL-2R-HA through specific binding to CD25. Dacliz...		IL Receptor
T28958	TG6-129	TG6 129	Prostaglandin Receptor
	TG6-129 is an antagonist of the EP2 receptor. TG6-129 suppresses PGE2-induced elevation of cAMP in cells expressing EP2 with an IC50 value of 1.6 µM. TG6-129 reduces the expression of COX-2, IL-1β, IL-6, IL-12, IL-23 and...		Prostaglandin Receptor
T3533	Apilimod mesylate	STA 5326 mesylate	IL Receptor , PI3K , Interleukin
	Apilimod mesylate (STA 5326 mesylate) is a potent IL-12/IL-23 inhibitor.		IL Receptor , PI3K , Interleukin
T9656	AP-1/NF-κB activation inhibitor 1		NF-κB , DNA/RNA Synthesis
	AP-1/NF-κB activation inhibitor 1 is a potent inhibitor of AP-1 and NF-κB mediated transcriptional activation ( IC 50 =1 μM), does not blocking basal transcription driven by the β-actin promoter. AP-1/NF-κB activation in...		NF-κB , DNA/RNA Synthesis
T77675	TNKS-2-IN-1		PARP , Wnt/beta-catenin , Antibiotic
	TNKS-2-IN-1 is a TNKS-2 inhibitor.TNKS-2-IN-1 inhibits TNKS-1 and TNKS-2 with IC50s of 259 nM and 1100 nM, respectively.TNKS-2-IN-1 has antimicrobial activity against E. coli and S. aureus.TNKS-2-IN-1 inhibits the releas...		PARP , Wnt/beta-catenin , Antibiotic
T2018	Apilimod	STA 5326	IL Receptor , PI3K , Interleukin
	Apilimod (STA 5326) inhibits the production of IL-12 and IL-23 and reduces dendritic cell infiltration in psoriasis.		IL Receptor , PI3K , Interleukin
T24816	SP-100030	SP100030,SP 100030	NF-κB
	SP-100030 is a dual inhibitor of NF-κB and activator protein-1 (AP-1), demonstrating potent inhibition with IC50 values of 50 nM for both. It effectively reduces the production of IL-2, IL-8, and TNF-alpha in Jurkat and ...		NF-κB
T23796	BIRT-377	BIRT377,BIRT 377	IL Receptor , Integrin
	BIRT-377 is a negative allosteric and orally bioavailable inhibitor of ICAM-1 and LFA-1(Ki = 25.8 nM). BIRT-377 inhibits the production of IL-2 and can be used in studies about inflammatory and immune disorders.		IL Receptor , Integrin
T25150	BI-69A11	BI 69A11,(E)-3-(1H-Benzo[d]imidazol-2-yl)-1-(6-chloro-2-hydroxy-4-phenylquinolin-3-yl)prop-2-en-1-one	NF-κB , Akt
	BI-69A11 ((E)-3-(1H-Benzo[d]imidazol-2-yl)-1-(6-chloro-2-hydroxy-4-phenylquinolin-3-yl)prop-2-en-1-one) is a dual AKT and NFkB pathway inhibitor. It enhances the susceptibility of colon cancer cells to mda-7/IL-24-induce...		NF-κB , Akt
T8546	BD750		JAK , STAT
	BD750 is an effective immunosuppressant and a JAK3/STAT5 inhibitor, inhibits IL-2-induced JAK3/STAT5-dependent T cell proliferation(IC50 of 1.5 μM and 1.1 μM in mouse and human T cells, respectively)		JAK , STAT
T3571	SU5201	NSC 247030	Others , Interleukin
	SU5201 (NSC 247030) is a biochemical.		Others , Interleukin
T77677	12R-LOX-IN-2		Lipoxygenase
	12R-LOX-IN-2 is an inhibitor of 12R-lipoxygenase (12R-LOX).12R-LOX-IN-2 inhibits imiquimod (IMQ)-induced hyperproliferation of psoriatic keratinocytes and inhibits colony formation.12R-LOX-IN-2 also decreases the protein...		Lipoxygenase
T77579	JC2-11		IL Receptor , Dehydrogenase , ROS , Caspase , NOD-like Receptor (NLR) , AIM2
	JC2-11 is an inhibitory compound for inflammation.JC2-11 inhibits the recruitment domain-containing proteins NLRC 4, atypical in melanoma 2 (AIM 2) and atypical (NC) inflammatory vesicles by disrupting reactive oxygen sp...
T38361	GSK717		IL Receptor , NOD
	GSK717 is a potent, selective NOD2 (nucleotide-binding oligomerization domain 2) inhibitor. GSK717 inhibits muramyl dipeptide (MDP)-induced NOD2-mediated signaling, with an IC50 of 400 nM for MDP-stimulated IL-8 secretio...		IL Receptor , NOD
T15017	CU-T12-9		TLR
	CU-T12-9 is a potent TLR1/2 agonist(EC50 of 52.9 nM in HEK-Blue hTLR2 SEAP assay). It acts by activating the NFkB pathway, upregulating proinflammatory cytokines, and enhancing TLR1 and TLR2 dimerization.CU-T12-9 activat...		TLR
T2548	Diflorasone		Glucocorticoid Receptor
	Diflorasone is a synthetic glucocorticoid with anti-inflammatory and immunosuppressive properties. Like other glucocorticoids, diflorasone enters the cell by diffusion across the cell membrane and binds to the glucocorti...		Glucocorticoid Receptor
T14687	Deucravacitinib	BMS-986165	Tyrosine Kinases , JAK , IFNAR , Interleukin
	Deucravacitinib (BMS-986165) inhibits IL-12/23 and type I IFN pathways[1][2]. BMS-986165 is a highly selective, orally bioavailable allosteric TYK2 inhibitor for the treatment of autoimmune diseases. Which selectively bi...		Tyrosine Kinases , JAK , IFNAR , Interleukin
T7123	AMG-47a		VEGFR , p38 MAPK , JAK , Src
	AMG-47a is a potent inhibitor of Lck and T cell proliferation. AMG-47a could promote the degradation of the KRAS oncoprotein. AMG-47a selectively reduced the levels of EGFP-KRASG12V protein but did not affect EGFP protei...		VEGFR , p38 MAPK , JAK , Src
T73463	NX-2127	NX2127,NX 2127	BTK
	NX-2127 (ETX2514 Triethylamine) is an orally active BTK inhibitor that induces degradation of mutant BTKC481S in cells.NX-2127 has potent antiproliferative activity and inhibits the proliferation of BTKC481S mutant TMD8 ...		BTK
T7672	MD2-TLR4-IN-1		TLR
	MD2-TLR4-IN-1 is a myeloid differentiation protein 2/toll-like receptor 4 (MD2-TLR4) complex inhibitor.		TLR
T3614	Inosine pranobex	Groprinosin,Isoprinosine,Immunovir,Delimmun	IL Receptor , HIV Protease
	Inosine pranobex (Delimmun) has a number of immunomodulatory effects, including inducing T-lymphocyte differentiation, augmenting macrophage and NK cell functions, and stimulating IL-2 production. Through these effects a...		IL Receptor , HIV Protease
T0304	Methylthiouracil	NSC-193526,NSC-9378,MTU	ERK , Antiviral , TNF , NF-κB , Interleukin
	Methylthiouracil (NSC-193526) is a thiourea antithyroid agent that inhibits the synthesis of thyroid hormone, and it is used to treat hyperthyroidism.		ERK , Antiviral , TNF , NF-κB , Interleukin
T0708	Oxaprozin	Oxaprozinum,Wy21743	NF-κB , COX
	Oxaprozin (Oxaprozinum) is a Nonsteroidal Anti-inflammatory Drug. The mechanism of action of oxaprozin is as a Cyclooxygenase Inhibitor. The chemical classification of oxaprozin is Nonsteroidal Anti-inflammatory Compound...		NF-κB , COX
T9216	MLT-943	MLT943	MALT
	MLT-943 is a potent, selective and orally active MALT1 protease inhibitor. [1].		MALT
T4615	Balsalazide sodium hydrate	Balsalazide disodium dihydrate,Balsalazide disodium salt dihydrate,Balsalazide disodium	STAT , Interleukin
	Balsalazide sodium hydrate (Balsalazide disodium) is an anti-inflammatory compound used in the treatment of Inflammatory Bowel Disease.Balsalazide sodium hydrate is a new 5-aminosalicylic acid (5-ASA) containing prodrug....		STAT , Interleukin
T12982	SP4206		IL Receptor
	SP4206 is an interaction inhibitor of IL-2/IL-2Rα (IL-2 and IL-2Rα with Kd of 70 nM and 10 nM,respectively)		IL Receptor
T28599	Ro26-4550	Ro 26-4550,Ro-26-4550
	Ro26-4550 is a competitive reversible inhibitor of interleukin-2 (IL-2) binding to IL-2R α-subunit (IC50 = 3 μM).
T27708	K-14585
	K-14585 is a proteinase-activated receptor 2 antagonist. K-14585 inhibited PAR(2)-mediated p65 NFkappaB phosphorylation and NFkappaB-DNA binding. K-14585 inhibited SLIGKV-stimulated IL-8 production, but given alone incre...
T12245	Nosantine racemate	NPT-15392 racemate	IL Receptor
	Nosantine racemate is the racemate of Nosantine which is a IL-2 inducer or enhancer of IL-2 induction by phytohemagglutinin (PHA).		IL Receptor
T26753	BC12-4
	BC12-4 is a novel potent inhibitor of IL-2 secretion, it has potent immunomodulatory activity.
T69235	TB-2-081
	TB-2-081 is a antagonist of IL-6 signaling.
T76185	N-Myristoyl-Lys-Arg-Thr-Leu-Arg
	N-Myristoyl-Lys-Arg-Thr-Leu-Arg is a protein kinase C (PKC) inhibitor, demonstrating an IC50 value of 75 μM. It effectively inhibits IL-2 receptor induction and IL-2 production in the human leukemic cell line Jurkat [1].

Compounds

Target: Dopamine Receptor, 5-HT Receptor

IRAK-4 protein kinase inhibitor 2

T9631

Synonym:

Target: IRAK

2,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide

Target: p38 MAPK, Serine Protease, MAPK

Loxapine succinate

T1412

Synonym: Daxolin,Loxapac,Cloxazepin,Loxapine succinate salt

Target: Dopamine Receptor, 5-HT Receptor

Synonym: 2-Anilinobenzoic acid,Diphenylamine-2-carboxylic acid,2-(Phenylamino)benzoic acid,N-Phenylanthranilic acid

Target: Chloride channel

Peldesine

T12399

Synonym: BCX 34

Target: Nucleoside Antimetabolite/Analog, HIV Protease

Target: IL Receptor, Calcium Channel, Interleukin

Synonym: ASP015K,JNJ-54781532

Target: Tyrosine Kinases, JAK

NFAT Transcription Factor Regulator-1

Synonym: Risankizumab rzaa,SKYRIZI,ABBV 066,BI-655066

Synonym: Ro 24-7375,Zenapax

Target: Prostaglandin Receptor

Apilimod mesylate

T3533

Synonym: STA 5326 mesylate

Target: IL Receptor, PI3K, Interleukin

AP-1/NF-κB activation inhibitor 1

T9656

Synonym:

Target: NF-κB, DNA/RNA Synthesis

TNKS-2-IN-1

T77675

Synonym:

Target: PARP, Wnt/beta-catenin, Antibiotic

Apilimod

T2018

Synonym: STA 5326

Target: IL Receptor, PI3K, Interleukin

SP-100030

T24816

Synonym: SP100030,SP 100030

Target: NF-κB

BIRT-377

T23796

Synonym: BIRT377,BIRT 377

Target: IL Receptor, Integrin

BI-69A11

T25150

Synonym: BI 69A11,(E)-3-(1H-Benzo[d]imidazol-2-yl)-1-(6-chloro-2-hydroxy-4-phenylquinolin-3-yl)prop-2-en-1-one

Target: Others, Interleukin

Target: IL Receptor, Dehydrogenase, ROS, Caspase, NOD-like Receptor (NLR), AIM2

GSK717

T38361

Synonym:

Target: IL Receptor, NOD

Target: Glucocorticoid Receptor

Deucravacitinib

T14687

Synonym: BMS-986165

Target: Tyrosine Kinases, JAK, IFNAR, Interleukin

AMG-47a

T7123

Synonym:

Target: VEGFR, p38 MAPK, JAK, Src

NX-2127

T73463

Synonym: NX2127,NX 2127

Synonym: Groprinosin,Isoprinosine,Immunovir,Delimmun

Target: IL Receptor, HIV Protease

Methylthiouracil

T0304

Synonym: NSC-193526,NSC-9378,MTU

Target: ERK, Antiviral, TNF, NF-κB, Interleukin

Oxaprozin

T0708

Synonym: Oxaprozinum,Wy21743

Balsalazide sodium hydrate

T4615

Synonym: Balsalazide disodium dihydrate,Balsalazide disodium salt dihydrate,Balsalazide disodium

Target: STAT, Interleukin

Synonym: Ro 26-4550,Ro-26-4550

Synonym: NPT-15392 racemate

N-Myristoyl-Lys-Arg-Thr-Leu-Arg

T76185

Synonym:

Target:

Cat No.	Product Name	Synonyms	Targets
TCS2170	2,5-Dihydroxyacetophenone	Quinacetophenone,2-Acetylhydroquinone,2-5-dihydroxyacetophenone,Acetylhydroquinone,DHAP	ERK , NF-κB , Tyrosinase
	1. 2,5-Dihydroxyacetophenone (Quinacetophenone) possess anti-anxiety, and neuroprotective qualities. 2. 2,5-Dihydroxyacetophenone (Quinacetophenone) reatment can induce a sustained activation of JNK, ERK1/2, and p38 MAPK...		ERK , NF-κB , Tyrosinase
T5758	Sphondin		COX , Prostaglandin Receptor
	Sphondin has anticonvulsant, anti-inflammatory, and anti-proliferative activities, it possessed an inhibitory effect on IL-1beta-induced increase in the level of COX-2 protein and PGE(2) release in A549 cells.		COX , Prostaglandin Receptor
TN6778	Umbelliprenin	7-[[(2E,6E)-3,7,11-Trimethyl-2,6,10-dodecatrienyl]oxy]-2H-1-benzopyran-2-oneUmbelliprenin	IL Receptor
	Umbelliprenin (7-[[(2E,6E)-3,7,11-Trimethyl-2,6,10-dodecatrienyl]oxy]-2H-1-benzopyran-2-oneUmbelliprenin) alleviated neuropathic pain, and decreased serum IL-6 levels and oxidative stress.		IL Receptor
TC0036	Compound Lup-20(29)-en-3-yl acetate		IL Receptor , VEGFR , Others , TNF , COX
	Lupeol acetate, a derivative of Lupeol, inhibits the progression of rheumatoid arthritis by downregulating TNF-α, IL-1β, MCP-1, COX-2, VEGF and granzyme B.		IL Receptor , VEGFR , Others , TNF , COX
T4S0795	Berberrubine chloride	9-Berberoline Chloride,Beroline,Beroline Chloride,Berberrubine,9-Berberoline	IL Receptor
	1. Berberrubine chloride (9-Berberoline Chloride) has antitumor activity. 2. Berberrubine has antidiabetic activity. 3. Berberrubine dose-dependently inhibits IL-8 and MCP-1 protein levels in the media and mRNA expressio...		IL Receptor
T6S0139	Neobavaisoflavone		Apoptosis , DNA/RNA Synthesis
	1. Neobavaisoflavone is isolated as a DNA polymerase inhibitor. 2. Neobavaisoflavone might be a potential anabolic agent to treat bone loss-associated diseases. 3. Neobavaisoflavone has anti-inflammatory activity, can si...		Apoptosis , DNA/RNA Synthesis
TN4379	Kansuinine A		IL Receptor , STAT , Interleukin
	Kansuinine A possesses analgesic props, it also shows NGF inducing activity.		IL Receptor , STAT , Interleukin
TN4661	Nodosin		IL Receptor , Autophagy
	Nodosin has anti-inflammatory function of Nodosin via inhibition of IL-2. Nodosin perfusion provides a potential protective effect through inducing HO-1 expression to attenuate ischemia/reperfusion injury in liver transp...		IL Receptor , Autophagy
T3829	Ginsenoside F3		Others , IFNAR , Interleukin
	Ginsenoside-F3 has immunoenhancing activity by regulating production and gene expression of type 1, type 2 cytokines in murine spleen cells. Ginsenoside-F3 enhances the NF-kappaB DNA binding activity induced by ConA in m...		Others , IFNAR , Interleukin
T5S1981	Alpha-Cyperone	(+)-α-Cyperone,α-Cyperone	Others , Endogenous Metabolite
	1. alpha-Cyperone (α-Cyperone) is a promising inhibitor of Hla production by S. aureus and protects lung cells from this bacterium. 2. alpha-Cyperone significantly inhibited PGE2 production by suppressing the LPS-induced...		Others , Endogenous Metabolite
T37280	PE(18:1(9Z)/0:0)		Endogenous Metabolite
	PE(18:1(9Z)/0:0) is a naturally-occurring lysophospholipid and an analog of plasmalogen lysophosphatidylethanolamine. PE(18:1(9Z)/0:0) induces transient increases in intracellular calcium in PC12 rat neuronal cells in a ...		Endogenous Metabolite
TN1110	Shanziside	Shanzhiside	IL Receptor
	Shanziside (Shanzhiside) has immunosuppressive activity, it shows significant inhibition of IL-2 secretion by phorbol myristate acetate and anti-CD28 monoclonal antibody co-stimulated activation of human peripheral blood...		IL Receptor
T6S1597	Mulberroside A		TNF , Tyrosinase , Interleukin
	1. Mulberroside has nephroprotective, hypoglycemic, and antidiabetic effects. 2. Mulberroside A is a glycosylated stilbene of oxyresveratrol; thus, the deglycosylation of Mulberroside A resulted in enhanced inhibition of...		TNF , Tyrosinase , Interleukin
T2758	Madecassic acid	6-Deoxy-L-Galactose,L-Fucose,Brahmic acid,L-fucopyranose	Others , TNF , COX , NO Synthase , Interleukin
	Madecassic acid (L-fucopyranose) is extracted from the whole herb of Centella asiatica.		Others , TNF , COX , NO Synthase , Interleukin
T8280	Deacetylasperulosidic Acid	Desacetyl asperulosidic acid	IL Receptor , Interleukin
	Deacetylasperulosidic Acid is a natural compound of Morinda citrifolia fruit. It has antioxidant activity by increasing superoxide dismutase activity. It also prevents 4-nitroquinoline 1-oxide (4NQO) induced DNA damage i...		IL Receptor , Interleukin
T20879	Tacrolimus monohydrate	FK-506,FR 900506,Prograf,FR900506,Tacrolimus hydrate,LCP-Tacro,FK 506	Phosphatase , Others , Antibacterial , Antibiotic , Autophagy
	Tacrolimus monohydrate (LCP-Tacro) is a macrolide from the culture broth of a strain of Streptomyces tsukubaensis, binds to FK506 binding protein (FKBP) to form a complex. Tacrolimus inhibits calcineurin phosphatase, whi...
T6S0077	Byakangelicol		COX
	1. Byakangelicol may inhibit P-gp expressed at the BBB even under in vivo conditions. 2. Byakangelicol can inhibit IL-1beta-induced PGE2 release in A549 cells; this inhibition may be mediated by suppression of COX-2 expr...		COX
T5S1058	Triptonide	PG 492,NSC 165677	Apoptosis , Wnt/beta-catenin , Autophagy
	1. Triptonide (PG 492) is effective in the treatment of autoimmune diseases and has potent antileukemic and antitumor activities. 2. Triptonide possesses anti-inflammatory activity, upregulate the expression of IL-37, an...		Apoptosis , Wnt/beta-catenin , Autophagy
T3S1513	(20R)-Protopanaxadiol	Protopanaxadiol,20R-Protopanaxadiol,(20R)-Protopanaxdiol	Others , Antibacterial
	1. (20R)-Protopanaxadiol ((20R)-Protopanaxdiol) has the effect of anti-tumor through increasing the activity of body immunity, inhibiting tumor interstitial microvascular density and its proliferation activity, improving...		Others , Antibacterial
T5S0167	Atractylenolide I		IL Receptor , TNF , TLR , JAK , STAT
	1. Atractylenolide-I has an anti-inflammatory effect by inhibiting TNF-α and IL-6 production; ameliorates sepsis syndrome, liver and kidney functions by reduction of pro-inflammatory cytokines and LPS. 2. Atractylenolide...		IL Receptor , TNF , TLR , JAK , STAT
T0798	Triamcinolone	Fluoxyprednisolone,Aristocort,Rodinolone	Glucocorticoid Receptor , COX
	Triamcinolone (Aristocort) is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. Upon cell entry, triamcinolone binds to and activates the glucocorticoid receptor, which leads to transloca...		Glucocorticoid Receptor , COX
T6S1579	Monotropein	Monotropeine	Others
	1. Monotropein (Monotropeine) has antinociceptive action. 2. Monotropein has anti-apoptosis and anti-catabolic activity in chondrocytes. 3. Monotropein has anti-inflammatory action by inhibition of the expressions of inf...		Others
T4S2063	Tetrahydrocoptisine	STYLOPINE	ERK , p38 MAPK , NF-κB
	1. Tetrahydrocoptisine (STYLOPINE) has effective effects in suppressing inflammation. 2. Tetrahydrocoptisine possesses a protective effect on LPS-induced ALI through inhibiting of NF-κB signaling pathways, which may invo...		ERK , p38 MAPK , NF-κB
T4S0145	Corylifol A	Corylinin	hCE , STAT , UGT
	1. Corylifol A (Corylinin) displays cytotoxic activity against HepG2 and Hep3B hepatocellular carcinoma cell lines, with IC50 values of 4.6 and 13.5 ug/ml, respectively. 2. Corylifol A and Biochanin A can be the potentia...		hCE , STAT , UGT
T2795	Amygdalin	Laetrile	Others
	Amygdalin (Laetrile) has antifibrotic, antitumor, anti-inflammatory and analgesic effects, amygdalin joint HSYA could inhibit the degeneration of the endplate chondrocytes derived from intervertebral discs of rats induce...		Others
T38373	2-heptyl-3-hydroxy-4(1H)-Quinolone	2-heptyl-3-hydroxy-4(1H)-Quinolone,PQS,Pseudomonas Quinolone Signal	Others
	2-heptyl-3-hydroxy-4(1H)-Quinolone (Pseudomonas Quinolone Signal) is a quorum-sensing signalling molecule produced by Pseudomonas aeruginosa in response to increased cell density. It increases the expression of the lasB ...		Others
T4115	Auraptene	7-geranyloxycoumarin	MMP , BACE
	Auraptene is a coumarin derived from citrus plants that bears a geranyloxyl moiety at its C-7. It has anti-inflammatory, anti-carcinogenic, anti-bacterial, neuroprotective, and hepatoprotective activities. It inhibits le...		MMP , BACE
T4S1422	Praeruptorin E		Others , Calcium Channel
	1. Praeruptorin C and E can relax swine coronary artery and decrease contractility in guinea-pig left atria, these effects are similar in many respects to those displayed by drugs that have calcium entry blocking activit...		Others , Calcium Channel
T6S1917	Schisandrol B	Gomisin A,TJN-101,Besigomsin,Gamma-Schisandrin,Schizandrol B,Wuweizi alcohol-B	P450 , Reactive Oxygen Species , Autophagy
	1. Schisandrol B (Besigomsin) may exert neuroprotective effects by attenuating the microglia-mediated neuroinflammatory response via inhibiting the TLR4-mediated NF-κB and MAPKs signaling pathways. 2. Schisandrol B has a...		P450 , Reactive Oxygen Species , Autophagy
T6S1315	Oroxylin A	6-Methoxybaicalein,Baicalein 6-methyl ether	Virus Protease , HIF/HIF Prolyl-Hydroxylase , Autophagy
	1. Oroxylin A (Baicalein 6-methyl ether) has various anti-tumor effects including apoptosis, cell cycle arrest, drug-resistant reversion. 2. Oroxylin A possesses abilities of inhibiting the ATRA-induced IL-6 production v...		Virus Protease , HIF/HIF Prolyl-Hydroxylase , Autophagy
T6S1538	Neochlorogenic acid	trans-5-O-Caffeoylquinic acid,Neochlorogenate,5-O-Caffeoylquinic acid	TNF , NF-κB , COX , Antibacterial , Interleukin
	Neochlorogenic acid (trans-5-O-Caffeoylquinic acid) is an antioxidant compound used in the treatment of oxidative stress and related afflictions.		TNF , NF-κB , COX , Antibacterial , Interleukin
T6S1141	Ganoderic acid A		Apoptosis , NF-κB , Endogenous Metabolite , Autophagy
	1. Ganoderic acid A exhibits antitumor activity, mediated through its inhibitory effect on nuclear transcription factor-kappaB and activator protein-1. 2. Ganoderic acid A can induce proliferation inhibition, apoptosis a...		Apoptosis , NF-κB , Endogenous Metabolite , Autophagy
T2S2264	Linalool	Linalol,(±)-Linalool,Phantol	Apoptosis , IL Receptor , TNF , Endogenous Metabolite , iGluR
	1. Linalool (Linalol), a natural compound of the essential oils, has been shown to have antinociceptive, antimicrobial, and anti-inflammatory properties. 2. Linalool was protected against LPS/GalN-induced liver injury th...
T3744	Veratric acid	Veratrumenoic acid,3,4-Dimethoxybenzoic acid	Reactive Oxygen Species , COX
	Veratric acid (3,4-Dimethoxybenzoic acid) is a simple benzoic acid derived from plants and fruits with anti-oxidant, anti-inflammation and blood pressure-lowering effects.		Reactive Oxygen Species , COX
T2S0843	Negletein	7-O-Methylbaicalein,Baicalein-7-methylether	IL Receptor , TNF , NOS , Interleukin
	1. Negletein (7-O-Methylbaicalein) has anti-inflammatory and immunomodulatory activities via inhibition of TNF-α, iNOS and IL-1β. 2. Negletein as a neuroprotectant enhances the action of nerve growth factor and induces n...		IL Receptor , TNF , NOS , Interleukin
TN1458	Buddlejasaponin IV		PARP , Akt , Chk
	Buddlejasaponin IV has analgesic and anti-inflammatory effects, the inhibitions of the expressions of iNOS, COX-2, TNF-alpha, IL-1beta and IL-6 by blocking NF-kappaB activation.		PARP , Akt , Chk
T79970	Taxamairin B
	Taxamairin B is a potent anti-inflammatory compound that inhibits the expression of proinflammatory cytokines (TNF-α, IL-1β, and IL-6) and reduces the production of NO and ROS in LPS-induced RAW264.7 cells. Furthermore, ...
T75694	Lacto-N-neotetraose
	Lacto-N-neotetraose (LNnT), an endogenous metabolite, inhibits TNF-α-induced IL-8 secretion in immature epithelial cells, exhibits anti-inflammatory activity, and enhances wound closure [1] [2] [4].
T27174	Dihydrocelastrol	DHCE. (-)-Triptohypol C,Triptohypol C
	Dihydrocelastrol is synthesized by hydrogenation of celastrol, a treterpene isolated from Chinese medicinal plant Tripterygium regelii. Dihydrocelastrol could inhibit cell proliferation and promote apoptosis through casp...
TN5033	Skullcapflavone I		IL Receptor , Caspase , Prostaglandin Receptor
	Skullcapflavone I has anti-inflammatory and anti-allergic potential, it can significantly inhibit LPS stimulated NO and PGE(2) release in J774A.1 macrophages and inhibit LPS induced IL-6 production in a concentration dep...		IL Receptor , Caspase , Prostaglandin Receptor
TN2243	Sugiol	10-Deoxoxanthoperol	IL Receptor , TNF , ROS
	Sugiol (10-Deoxoxanthoperol) has antioxidant efficacy, it has significant scavenging activities of 1,1-diphenyl-2-picryl hydrazyl, nitric oxide, superoxide and hydroxyl free radicals. Sugiol's efficacy in inhibiting the ...		IL Receptor , TNF , ROS
T35741	Gliovirin
	Gliovirin is a fungal metabolite that has been found inT. harzianumand has fungicidal, antimicrobial and anti-inflammatory activities.1It is active against the plant pathogenic fungusP. ultimum(MIC = 60 ng/ml) and the pa...

Natural Products

2,5-Dihydroxyacetophenone

TCS2170

Synonym: Quinacetophenone,2-Acetylhydroquinone,2-5-dihydroxyacetophenone,Acetylhydroquinone,DHAP

Target: ERK, NF-κB, Tyrosinase

sphondin

T5758

Synonym:

Target: COX, Prostaglandin Receptor

Umbelliprenin

TN6778

Synonym: 7-[[(2E,6E)-3,7,11-Trimethyl-2,6,10-dodecatrienyl]oxy]-2H-1-benzopyran-2-oneUmbelliprenin

Target: IL Receptor

Compound Lup-20(29)-en-3-yl acetate

TC0036

Synonym:

Target: IL Receptor, VEGFR, Others, TNF, COX

Berberrubine chloride

T4S0795

Synonym: 9-Berberoline Chloride,Beroline,Beroline Chloride,Berberrubine,9-Berberoline

Target: Apoptosis, DNA/RNA Synthesis

Kansuinine A

TN4379

Synonym:

Target: IL Receptor, STAT, Interleukin

Nodosin

TN4661

Synonym:

Target: IL Receptor, Autophagy

Ginsenoside F3

T3829

Synonym:

Target: Others, IFNAR, Interleukin

alpha-Cyperone

T5S1981

Synonym: (+)-α-Cyperone,α-Cyperone

Target: Others, Endogenous Metabolite

PE(18:1(9Z)/0:0)

T37280

Synonym:

Target: Endogenous Metabolite

Target: TNF, Tyrosinase, Interleukin

Madecassic acid

T2758

Synonym: 6-Deoxy-L-Galactose,L-Fucose,Brahmic acid,L-fucopyranose

Target: Others, TNF, COX, NO Synthase, Interleukin

Deacetylasperulosidic Acid

T8280

Synonym: Desacetyl asperulosidic acid

Target: IL Receptor, Interleukin

Tacrolimus monohydrate

T20879

Synonym: FK-506,FR 900506,Prograf,FR900506,Tacrolimus hydrate,LCP-Tacro,FK 506

Target: Phosphatase, Others, Antibacterial, Antibiotic, Autophagy

Synonym: PG 492,NSC 165677

Target: Apoptosis, Wnt/beta-catenin, Autophagy

(20R)-Protopanaxadiol

T3S1513

Synonym: Protopanaxadiol,20R-Protopanaxadiol,(20R)-Protopanaxdiol

Target: Others, Antibacterial

Atractylenolide I

T5S0167

Synonym:

Target: IL Receptor, TNF, TLR, JAK, STAT

Triamcinolone

T0798

Synonym: Fluoxyprednisolone,Aristocort,Rodinolone

Target: Glucocorticoid Receptor, COX

Monotropein

T6S1579

Synonym: Monotropeine

Target: ERK, p38 MAPK, NF-κB

Corylifol A

T4S0145

Synonym: Corylinin

Target: hCE, STAT, UGT

2-heptyl-3-hydroxy-4(1H)-Quinolone

T38373

Synonym: 2-heptyl-3-hydroxy-4(1H)-Quinolone,PQS,Pseudomonas Quinolone Signal

Target: Others

Auraptene

T4115

Synonym: 7-geranyloxycoumarin

Target: Others, Calcium Channel

Schisandrol B

T6S1917

Synonym: Gomisin A,TJN-101,Besigomsin,Gamma-Schisandrin,Schizandrol B,Wuweizi alcohol-B

Target: P450, Reactive Oxygen Species, Autophagy

Oroxylin A

T6S1315

Synonym: 6-Methoxybaicalein,Baicalein 6-methyl ether

Target: Virus Protease, HIF/HIF Prolyl-Hydroxylase, Autophagy

Neochlorogenic acid

T6S1538

Synonym: trans-5-O-Caffeoylquinic acid,Neochlorogenate,5-O-Caffeoylquinic acid

Target: TNF, NF-κB, COX, Antibacterial, Interleukin

Ganoderic acid A

T6S1141

Synonym:

Target: Apoptosis, NF-κB, Endogenous Metabolite, Autophagy

Linalool

T2S2264

Synonym: Linalol,(±)-Linalool,Phantol

Target: Apoptosis, IL Receptor, TNF, Endogenous Metabolite, iGluR

Veratric acid

T3744

Synonym: Veratrumenoic acid,3,4-Dimethoxybenzoic acid

Target: Reactive Oxygen Species, COX

Negletein

T2S0843

Synonym: 7-O-Methylbaicalein,Baicalein-7-methylether

Target: IL Receptor, TNF, NOS, Interleukin

Buddlejasaponin IV

TN1458

Synonym:

Target: PARP, Akt, Chk

Synonym: DHCE. (-)-Triptohypol C,Triptohypol C

Target: IL Receptor, Caspase, Prostaglandin Receptor

Sugiol

TN2243

Synonym: 10-Deoxoxanthoperol

Target: IL Receptor, TNF, ROS

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-02788	IL-2 Protein, Mouse, Recombinant	Mouse	E. coli
	Interleukin-2, also known as a T-cell growth factor, TCGF, Aldesleukin, and IL2, is a secreted protein that belongs to the IL-2 family. Interleukin-2 / IL-2 was the first interleukin molecule to be discovered. Interleuki...
TMPJ-01463	IL-2 Protein, Human, Recombinant (E. coli)	Human	E. coli
	IL-2 Protein, Human, Recombinant (E. coli) is expressed in E. coli expression system. The accession number is P60568.
TMPJ-01464	IL-2 Superkine Protein, Human, Recombinant (L100F, R101D, L105V, I106V, I112F)	Human	Human Cells
	Interleukin-2(IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system，belongs to the IL-2 family. It is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or m...
TMPY-05784	CD122/IL2RB Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	Interleukin-2 receptor (IL-2R) also known as High-affinity IL-2 receptor subunit beta, IL-2 receptor subunit beta, and IL-2RB, is involved in T cell-mediated immune responses. CD122/IL-2RB is present in 3 forms concernin...
TMPY-04031	CD122/IL2RB Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Interleukin-2 receptor (IL-2R) also known as High-affinity IL-2 receptor subunit beta, IL-2 receptor subunit beta, and IL-2RB, is involved in T cell-mediated immune responses. CD122/IL-2RB is present in 3 forms concernin...
TMPY-01366	IL-1R2 Protein, Human, Recombinant (His)	Human	HEK293
	Interleukin 1 receptor, type II (IL1R2) also known as CD121b (Cluster of Differentiation 121b) is a cytokine receptor that belongs to the interleukin-1 receptor family. This protein binds interleukin alpha (IL1A), interl...
TMPY-03481	IL-1R2 Protein, Human, Recombinant	Human	HEK293
	Interleukin 1 receptor, type II (IL1R2) also known as CD121b (Cluster of Differentiation 121b) is a cytokine receptor that belongs to the interleukin-1 receptor family. This protein binds interleukin alpha (IL1A), interl...
TMPY-04239	IL-28A Protein, Human, Recombinant (His)	Human	Yeast
	IL-28A Protein, Human, Recombinant (His) is expressed in Yeast with His tag. The predicted molecular weight is 21.1 kDa. Accession number: Q8IZJ0
TMPY-06258	IL-2 Protein, Human, Recombinant	Human	HEK293
	Interleukin-2, also known as a T-cell growth factor, TCGF, Aldesleukin, and IL2, is a secreted protein that belongs to the IL-2 family. Interleukin-2 / IL-2 was the first interleukin molecule to be discovered. Interleuki...
TMPY-06196	IL-2 Protein, Human, Recombinant (His)	Human	HEK293
	Interleukin-2, also known as a T-cell growth factor, TCGF, Aldesleukin, and IL2, is a secreted protein that belongs to the IL-2 family. Interleukin-2 / IL-2 was the first interleukin molecule to be discovered. Interleuki...
TMPY-00860	CD122/IL2RB Protein, Human, Recombinant	Human	HEK293
	Interleukin-2 receptor (IL-2R) also known as High-affinity IL-2 receptor subunit beta, IL-2 receptor subunit beta, and IL-2RB, is involved in T cell-mediated immune responses. CD122/IL-2RB is present in 3 forms concernin...
TMPY-05216	CD122/IL2RB Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	Interleukin-2 receptor (IL-2R) also known as High-affinity IL-2 receptor subunit beta, IL-2 receptor subunit beta, and IL-2RB, is involved in T cell-mediated immune responses. CD122/IL-2RB is present in 3 forms concernin...
TMPY-01767	IL-12RB2 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Interleukin-12 receptor subunit beta-2 (IL12RB2), also known as IL-12 receptor subunit beta-2, IL-12R subunit beta-2, IL-12R-beta-2, and IL-12RB2, is a type I transmembrane protein identified as a subunit of the interleu...
TMPY-00863	IL-6 Protein, Human, Recombinant	Human	E. coli
	Interleukin-6 (IL-6) is a multifunctional α-helical cytokine that regulates cell growth and differentiation of various tissues, which is known particularly for its role in the immune response and acute phase reactions. I...
TMPY-05680	CD122/IL2RB Protein, Human, Recombinant (mFc)	Human	HEK293
	Interleukin-2 receptor (IL-2R) also known as High-affinity IL-2 receptor subunit beta, IL-2 receptor subunit beta, and IL-2RB, is involved in T cell-mediated immune responses. CD122/IL-2RB is present in 3 forms concernin...
TMPJ-00877	IL-2 Protein, Rat, Recombinant (His)	Rat	Human Cells
	Interleukin-2(IL-2)is a O-glycosylated four α-helix bundle cytokine that has potent stimulatory activity for antigenactivated T cells. It is expressed by CD4+ and CD8+ T cells, γδ T cells, B cells, dendritic cells, and e...
TMPY-04863	IL-12 Protein, Human, Recombinant	Human	HEK293
	IL-12 Protein, Human, Recombinant is expressed in HEK293. The predicted molecular weight is 57.2 kDa. Accession number: P29459-1&NP_002178.2
TMPY-00841	IL-13RA2 Protein, Human, Recombinant (His)	Human	HEK293
	Interleukin-13 receptor subunit alpha-2 (IL13RA2/IL-13RA2) is also known as cluster of differentiation 213A2 (CD213A2), IL-13 receptor subunit alpha-2, IL-13R subunit alpha-2, and IL-13RA2. The IL13RA2 is often overexpre...
TMPK-00320	IL-2 R beta/CD122 Protein, Human, Recombinant (His & Avi)	Human	HEK293
	IL-2 R beta is a member of the cytokine receptor superfamily. Human IL-2 R beta cDNA encodes a 551 amino acid residue precursor Type I membrane protein with a 26 residue signal peptide, a 214 residue extracellular region...
TMPJ-00850	ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His)	Mouse	Human Cells
	ST2, also called IL-1 R4, is an Interleukin-1 receptor family glycoprotein that plays a role in Th2 immune responses. ST2 is expressed on the surface of mast cells, activated Th2 cells, macrophages, and cardiac myocytes....
TMPY-01103	CD25/IL2R alpha Protein, Human, Recombinant (His)	Human	HEK293
	CD25 (alpha-chain of the IL-2 receptor, or IL2RA), is a type I transmembrane glycoprotein with a signal peptide, an extracellular region, a transmembrane region, and a cytoplasmic domain. IL2RA is expressed on activated ...
TMPY-05584	CD25/IL2R alpha Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	CD25 (alpha-chain of the IL-2 receptor, or IL2RA), is a type I transmembrane glycoprotein with a signal peptide, an extracellular region, a transmembrane region, and a cytoplasmic domain. IL2RA is expressed on activated ...
TMPJ-00036	IL-2 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	Human Cells
	Interleukin-2(IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system，belongs to the IL-2 family. It is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or m...
TMPY-01045	IL-12B Protein, Human, Recombinant (His)	Human	HEK293
	Subunit beta of interleukin 12 (also known as natural killer cell stimulatory factor 2, or cytotoxic lymphocyte maturation factor 2, p40) (IL12B) is a subunit of human interleukin 12. IL12B/IL-12B is a cytokine that acts...
TMPK-00321	IL-2 R beta/CD122 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated	Cynomolgus	HEK293
	IL-2 R beta is a member of the cytokine receptor superfamily. Human IL-2 R beta cDNA encodes a 551 amino acid residue precursor Type I membrane protein with a 26 residue signal peptide, a 214 residue extracellular region...
TMPY-02457	IL-2 Protein, Rat, Recombinant	Rat	E. coli
	Interleukin-2, also known as a T-cell growth factor, TCGF, Aldesleukin, and IL2, is a secreted protein that belongs to the IL-2 family. Interleukin-2 / IL-2 was the first interleukin molecule to be discovered. Interleuki...
TMPK-00164	IL-2 R alpha/CD25 Protein, Human, Recombinant (His & Avi)	Human	HEK293
	Human IL-2 receptor alpha (IL-2 R alpha), also known as Tac antigen and as CD25, was initially identified as a 55 kDa membrane glycoprotein that is capable of binding IL‑2.eceptor for interleukin-2. The receptor is invol...
TMPY-02926	IL-2RG Protein, Human, Recombinant (hFc)	Human	HEK293
	The common gamma chain (γc) (or CD132), also known as interleukin-2 receptor subunit gamma or IL2RG, is a member of the type I cytokine receptor family expressed on most lymphocyte (white blood cell) populations, and its...
TMPK-00165	IL-2 R alpha/CD25 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	Human IL-2 receptor alpha (IL-2 R alpha), also known as Tac antigen and as CD25, was initially identified as a 55 kDa membrane glycoprotein that is capable of binding IL‑2.eceptor for interleukin-2. The receptor is invol...
TMPK-00986	IL-2 R gamma/CD132 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	The gamma chain of the high affinity functional human IL-2 receptor complex belongs to the hematopoietin receptor family. IL-2 R gamma is a 369 amino acid residue protein consisting of a 22 residue signal sequence, a 232...
TMPK-00238	IL-2 R gamma/CD132 Protein, Human, Recombinant (His & Avi)	Human	HEK293
	The gamma chain of the high affinity functional human IL-2 receptor complex belongs to the hematopoietin receptor family. IL-2 R gamma is a 369 amino acid residue protein consisting of a 22 residue signal sequence, a 232...
TMPK-00239	IL-2 R gamma/CD132 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	The gamma chain of the high affinity functional human IL-2 receptor complex belongs to the hematopoietin receptor family. IL-2 R gamma is a 369 amino acid residue protein consisting of a 22 residue signal sequence, a 232...
TMPK-00769	IL-2 Protein, Mouse, Recombinant (His & Avi)	Mouse	HEK293
	Interleukin-2 (IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system. It is a 15,5 - 16 kDa protein that regulates the activities of white blood cells (leukocytes, often lymphocytes) that ar...
TMPK-00987	IL-2 R gamma/CD132 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated	Cynomolgus	HEK293
	The gamma chain of the high affinity functional human IL-2 receptor complex belongs to the hematopoietin receptor family. IL-2 R gamma is a 369 amino acid residue protein consisting of a 22 residue signal sequence, a 232...
TMPK-00770	IL-2 Protein, Mouse, Recombinant (His & Avi), Biotinylated	Mouse	HEK293
	Interleukin-2 (IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system. It is a 15,5 - 16 kDa protein that regulates the activities of white blood cells (leukocytes, often lymphocytes) that ar...
TMPY-00093	IL-31RA Protein, Human, Recombinant (hFc)	Human	HEK293
	IL-31RA Protein, Human, Recombinant (hFc) is expressed in HEK293 with hFc tag. The predicted molecular weight is 83.5 kDa. Accession number: EAW54932.1
TMPY-04236	IL-31RA Protein, Human, Recombinant (His)	Human	HEK293
	IL-31RA Protein, Human, Recombinant (His) is expressed in HEK293 cells.
TMPY-00849	ST2/IL-1 RL1 Protein, Human, Recombinant (hFc)	Human	HEK293
	IL-1 receptor–like 1 (IL1RL1) is a membrane receptor involved in TH2 inflammatory responses and eosinophilia. It has previously been described that levels of the interleukin-1 like 1 (IL1RL1) protein can be used to diagn...
TMPY-00850	ST2/IL-1 RL1 Protein, Human, Recombinant	Human	HEK293
	IL-1 receptor–like 1 (IL1RL1) is a membrane receptor involved in TH2 inflammatory responses and eosinophilia. It has previously been described that levels of the interleukin-1 like 1 (IL1RL1) protein can be used to diagn...
TMPY-01359	ST2/IL-1 RL1 Protein, Human, Recombinant (His)	Human	HEK293
	IL-1 receptor–like 1 (IL1RL1) is a membrane receptor involved in TH2 inflammatory responses and eosinophilia. It has previously been described that levels of the interleukin-1 like 1 (IL1RL1) protein can be used to diagn...
TMPK-00243	IL-13Ra2 Protein, Human, Recombinant (hFc)	Human	HEK293
	Two type 1 membrane proteins belonging to the hemopoietin receptor family have been cloned and shown to bind IL-13 with differing affinities. The lower affinity IL-13 binding protein, previously designated IL-13 R alpha,...
TMPJ-00398	IL-12RB2 Protein, Mouse, Recombinant (hFc)	Mouse	Human Cells
	The IL12 receptor complex, formed by IL12RB1 and IL12RB2, mediates the type I immune responses of various types of lymphocytes. Its ligand, IL12, is a heterodimeric cytokine composed of IL-12p35 and IL-12p40 subunits tha...
TMPY-01324	IL-22BP Protein, Human, Recombinant (His & hFc)	Human	HEK293
	Interleukin-22 receptor subunit alpha-2 (IL-22RA2), also known as interleukin-22-binding protein (IL-22BP), is a subunit of the receptor for interleukin 22. IL-22BP belongs to the type II cytokine receptor family and con...
TMPK-00244	IL-13RA2 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Two type 1 membrane proteins belonging to the hemopoietin receptor family have been cloned and shown to bind IL-13 with differing affinities. The lower affinity IL-13 binding protein, previously designated IL-13 R alpha,...
TMPY-00848	IL-1R2 Protein, Human, Recombinant (hFc)	Human	HEK293
	Interleukin 1 receptor, type II (IL1R2) also known as CD121b (Cluster of Differentiation 121b) is a cytokine receptor that belongs to the interleukin-1 receptor family. This protein binds interleukin alpha (IL1A), interl...
TMPJ-00326	CD122/IL2RB Protein, Human, Recombinant (aa 27-239, His & Avi), Biotinylated	Human	Human Cells
	Human IL-2RB, also known asinterleukin-2 receptor subunit beta,is the receptor for interleukin-2. IL2 receptor complex is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. IL2 recepto...
TMPY-04900	IL-22BP Protein, Human, Recombinant (hFc)	Human	HEK293
	Interleukin-22 receptor subunit alpha-2 (IL-22RA2), also known as interleukin-22-binding protein (IL-22BP), is a subunit of the receptor for interleukin 22. IL-22BP belongs to the type II cytokine receptor family and con...
TMPY-01220	IL-22BP Protein, Human, Recombinant (His)	Human	HEK293
	Interleukin-22 receptor subunit alpha-2 (IL-22RA2), also known as interleukin-22-binding protein (IL-22BP), is a subunit of the receptor for interleukin 22. IL-22BP belongs to the type II cytokine receptor family and con...
TMPJ-01314	IL-1RL2 Protein, Mouse, Recombinant (hFc)	Mouse	Human Cells
	Interleukin-1 receptor-like 2 is a protein that in humans is encoded by the IL1RL2 gene, belongs to the interleukin-1 receptor family.IL1RL2 is the receptor for interleukin-36 (IL36A, IL36B and IL36G). After binding to i...
TMPK-00084	IL-17C Protein, Human, Recombinant (His & Avi)	Human	HEK293
	Interleukin‑17C (IL‑17C) is a 15‑20 kDa glycosylated cytokine that plays an important role in mucosal immunity and chronic inflammation. The six IL‑17 cytokines (IL‑17A‑F) are encoded by separate genes but adopt a conser...
------------------------ More ------------------------

IL-2 Protein, Mouse, Recombinant

TMPY-02788

Species: Mouse

Expression System: E. coli

IL-2 Protein, Human, Recombinant (E. coli)

TMPJ-01463

Species: Human

Expression System: E. coli

IL-2 Superkine Protein, Human, Recombinant (L100F, R101D, L105V, I106V, I112F)

TMPJ-01464

Species: Human

Expression System: Human Cells

CD122/IL2RB Protein, Mouse, Recombinant (hFc)

TMPY-05784

Species: Mouse

Expression System: HEK293

CD122/IL2RB Protein, Mouse, Recombinant (His)

TMPY-04031

Species: Mouse

Expression System: HEK293

IL-1R2 Protein, Human, Recombinant (His)

TMPY-01366

Species: Human

Expression System: HEK293

IL-1R2 Protein, Human, Recombinant

TMPY-03481

Species: Human

Expression System: HEK293

IL-28A Protein, Human, Recombinant (His)

TMPY-04239

Species: Human

Expression System: Yeast

IL-2 Protein, Human, Recombinant

TMPY-06258

Species: Human

Expression System: HEK293

IL-2 Protein, Human, Recombinant (His)

TMPY-06196

Species: Human

Expression System: HEK293

CD122/IL2RB Protein, Human, Recombinant

TMPY-00860

Species: Human

Expression System: HEK293

CD122/IL2RB Protein, Human, Recombinant (His)

TMPY-05216

Species: Human

Expression System: Baculovirus-Insect Cells

IL-12RB2 Protein, Mouse, Recombinant (His)

TMPY-01767

Species: Mouse

Expression System: HEK293

IL-6 Protein, Human, Recombinant

TMPY-00863

Species: Human

Expression System: E. coli

CD122/IL2RB Protein, Human, Recombinant (mFc)

TMPY-05680

Species: Human

Expression System: HEK293

IL-2 Protein, Rat, Recombinant (His)

TMPJ-00877

Species: Rat

Expression System: Human Cells

IL-12 Protein, Human, Recombinant

TMPY-04863

Species: Human

Expression System: HEK293

IL-13RA2 Protein, Human, Recombinant (His)

TMPY-00841

Species: Human

Expression System: HEK293

IL-2 R beta/CD122 Protein, Human, Recombinant (His & Avi)

TMPK-00320

Species: Human

Expression System: HEK293

ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His)

TMPJ-00850

Species: Mouse

Expression System: Human Cells

CD25/IL2R alpha Protein, Human, Recombinant (His)

TMPY-01103

Species: Human

Expression System: HEK293

CD25/IL2R alpha Protein, Human, Recombinant (His & Avi), Biotinylated

TMPY-05584

Species: Human

Expression System: HEK293

IL-2 Protein, Human, Recombinant (His & Avi), Biotinylated

TMPJ-00036

Species: Human

Expression System: Human Cells

IL-12B Protein, Human, Recombinant (His)

TMPY-01045

Species: Human

Expression System: HEK293

IL-2 R beta/CD122 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated

TMPK-00321

Species: Cynomolgus

Expression System: HEK293

IL-2 Protein, Rat, Recombinant

TMPY-02457

Species: Rat

Expression System: E. coli

IL-2 R alpha/CD25 Protein, Human, Recombinant (His & Avi)

TMPK-00164

Species: Human

Expression System: HEK293

IL-2RG Protein, Human, Recombinant (hFc)

TMPY-02926

Species: Human

Expression System: HEK293

IL-2 R alpha/CD25 Protein, Human, Recombinant (His & Avi), Biotinylated

TMPK-00165

Species: Human

Expression System: HEK293

IL-2 R gamma/CD132 Protein, Cynomolgus, Recombinant (His)

TMPK-00986

Species: Cynomolgus

Expression System: HEK293

IL-2 R gamma/CD132 Protein, Human, Recombinant (His & Avi)

TMPK-00238

Species: Human

Expression System: HEK293

IL-2 R gamma/CD132 Protein, Human, Recombinant (His & Avi), Biotinylated

TMPK-00239

Species: Human

Expression System: HEK293

IL-2 Protein, Mouse, Recombinant (His & Avi)

TMPK-00769

Species: Mouse

Expression System: HEK293

IL-2 R gamma/CD132 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated

TMPK-00987

Species: Cynomolgus

Expression System: HEK293

IL-2 Protein, Mouse, Recombinant (His & Avi), Biotinylated

TMPK-00770

Species: Mouse

Expression System: HEK293

IL-31RA Protein, Human, Recombinant (hFc)

TMPY-00093

Species: Human

Expression System: HEK293

IL-31RA Protein, Human, Recombinant (His)

TMPY-04236

Species: Human

Expression System: HEK293

ST2/IL-1 RL1 Protein, Human, Recombinant (hFc)

TMPY-00849

Species: Human

Expression System: HEK293

ST2/IL-1 RL1 Protein, Human, Recombinant

TMPY-00850

Species: Human

Expression System: HEK293

ST2/IL-1 RL1 Protein, Human, Recombinant (His)

TMPY-01359

Species: Human

Expression System: HEK293

IL-13Ra2 Protein, Human, Recombinant (hFc)

TMPK-00243

Species: Human

Expression System: HEK293

IL-12RB2 Protein, Mouse, Recombinant (hFc)

TMPJ-00398

Species: Mouse

Expression System: Human Cells

IL-22BP Protein, Human, Recombinant (His & hFc)

TMPY-01324

Species: Human

Expression System: HEK293

IL-13RA2 Protein, Mouse, Recombinant (His)

TMPK-00244

Species: Mouse

Expression System: HEK293

IL-1R2 Protein, Human, Recombinant (hFc)

TMPY-00848

Species: Human

Expression System: HEK293

CD122/IL2RB Protein, Human, Recombinant (aa 27-239, His & Avi), Biotinylated

TMPJ-00326

Species: Human

Expression System: Human Cells

IL-22BP Protein, Human, Recombinant (hFc)

TMPY-04900

Species: Human

Expression System: HEK293

IL-22BP Protein, Human, Recombinant (His)

TMPY-01220

Species: Human

Expression System: HEK293

IL-1RL2 Protein, Mouse, Recombinant (hFc)

TMPJ-01314

Species: Mouse

Expression System: Human Cells

IL-17C Protein, Human, Recombinant (His & Avi)

TMPK-00084

Species: Human

Expression System: HEK293

--------- More ---------

Cat No.	Product Name
L3800	NF-κB Signaling Compound Library	729 compounds
	A unique collection of 729 compounds targeting NF-κB signaling for high throughput screening and high content screening;
L7600	Chemokine Inhibitor Library	59 compounds
	A unique collection of 59 chemokines or chemokine receptors targeted compounds for high throughput and high content screening;

Libraries

NF-κB Signaling Compound Library

L3800

Compounds: 729

Chemokine Inhibitor Library

L7600

Compounds: 59