Shopping Cart

Your shopping cart is currently empty

Neochlorogenic acid

Name: Neochlorogenic acid
Brand: TargetMol
SKU: T6S1538
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

Copy Product Info

😃Good

Catalog No. T6S1538Cas No. 906-33-2

Alias trans-5-O-Caffeoylquinic acid, Neochlorogenate, 5-O-Caffeoylquinic acid

Neochlorogenic acid (trans-5-O-Caffeoylquinic acid) is an antioxidant compound used in the treatment of oxidative stress and related afflictions.

Neochlorogenic acid

Copy Product Info

😃Good

Purity: 99.54%

Catalog No. T6S1538Alias trans-5-O-Caffeoylquinic acid, Neochlorogenate, 5-O-Caffeoylquinic acidCas No. 906-33-2

Neochlorogenic acid (trans-5-O-Caffeoylquinic acid) is an antioxidant compound used in the treatment of oxidative stress and related afflictions.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$30	In Stock	In Stock
5 mg	$68	In Stock	In Stock
10 mg	$97	In Stock	In Stock
25 mg	$158	In Stock	In Stock
50 mg	$232	In Stock	In Stock
100 mg	$343	In Stock	In Stock
200 mg	$497	-	In Stock
1 mL x 10 mM (in DMSO)	$74	In Stock	In Stock

Add to Cart

Add to Quotation

In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

Select Batch

Purity:99.54%

Appearance:Solid

Color:White

Resource Download

COA LCMS HNMR

Product Introduction

Neochlorogenic acid AI Summary

Neochlorogenic acid exhibits a range of bioactivities, most notably antioxidant properties and enzyme inhibition. It demonstrates strong antioxidant activities with SOD-like activity (IC50 = 1.5 µg/mL) and DPPH radical scavenging activity (EC50 values of 13.4 µg/mL and 17.0 µg/mL), indicating its potential to reduce oxidative stress. Additionally, Neochlorogenic acid shows inhibitory activity against Histone Deacetylase (HDAC) with an IC50 value of 170400.0 nM in human HeLa nuclear extract assays and >200000.0 nM in HeLa cell assays. It also inhibits PTP1B with an IC50 value of 31600.0 nM. Furthermore, the compound targets Leishmania major DHODH with IC50 values of 1125000.0 nM and 1258925.41 nM. In cellular assays, it inhibits M-CSF/RANKL-induced osteoclast differentiation with an IC50 of 48000.0 nM and enhances osteoblastogenic activity, leading to a 120% and 170% increase in ALP activity at 10 µM and 50 µM, respectively, in mouse MC3T3-E1 cells..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Neochlorogenic acid (trans-5-O-Caffeoylquinic acid) is an antioxidant compound used in the treatment of oxidative stress and related afflictions.
Synonyms	trans-5-O-Caffeoylquinic acid, Neochlorogenate, 5-O-Caffeoylquinic acid

Chemical Properties

Molecular Weight	354.31
Formula	C₁₆H₁₈O₉
Cas No.	906-33-2
Smiles	O[C@@H]1C[C@@](O)(C[C@@H](OC(=O)\C=C\c2ccc(O)c(O)c2)[C@H]1O)C(O)=O
Relative Density.	1.65 g/cm3 (Predicted)

Storage & Solubility Information

Storage

In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 255 mg/mL (719.71 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.8224 mL	14.1119 mL	28.2239 mL	141.1194 mL
5 mM	0.5645 mL	2.8224 mL	5.6448 mL	28.2239 mL
10 mM	0.2822 mL	1.4112 mL	2.8224 mL	14.1119 mL
20 mM	0.1411 mL	0.7056 mL	1.4112 mL	7.0560 mL
50 mM	0.0564 mL	0.2822 mL	0.5645 mL	2.8224 mL
100 mM	0.0282 mL	0.1411 mL	0.2822 mL	1.4112 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc