Powder: -20°C for 3 years | In solvent: -80°C for 1 year
1. Tetrahydrocoptisine (STYLOPINE) has effective effects in suppressing inflammation. 2. Tetrahydrocoptisine possesses a protective effect on LPS-induced ALI through inhibiting of NF-κB signaling pathways, which may involve the inhibition of pulmonary inflammatory process. 3. Tetrahydrocoptisine has gastroprotective activity, is attributed to reducing NO production and adjusting the pro-inflammatory cytokine, inhibited neutrophil accumulation and NF-κB expression. 4. Tetrahydrocoptisine is an active anti-inflammatory constituent by inhibition of TNF-α, IL-6 and NO production possibly via down-regulation of NF-κB activation, phospho-ERK1/2 and phospho-p38 MAPK signal pathways.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 44.00 | |
5 mg | In stock | $ 97.00 | |
10 mg | In stock | $ 155.00 | |
25 mg | In stock | $ 262.00 | |
50 mg | In stock | $ 389.00 | |
100 mg | In stock | $ 573.00 |
Description | 1. Tetrahydrocoptisine (STYLOPINE) has effective effects in suppressing inflammation. 2. Tetrahydrocoptisine possesses a protective effect on LPS-induced ALI through inhibiting of NF-κB signaling pathways, which may involve the inhibition of pulmonary inflammatory process. 3. Tetrahydrocoptisine has gastroprotective activity, is attributed to reducing NO production and adjusting the pro-inflammatory cytokine, inhibited neutrophil accumulation and NF-κB expression. 4. Tetrahydrocoptisine is an active anti-inflammatory constituent by inhibition of TNF-α, IL-6 and NO production possibly via down-regulation of NF-κB activation, phospho-ERK1/2 and phospho-p38MAPK signal pathways. |
Source |
Synonyms | STYLOPINE |
Molecular Weight | 323.34 |
Formula | C19H17NO4 |
CAS No. | 4312-32-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.: Soluble
DMSO: 4.17 mg/mL (12.89 mM), Sonification is recommended
You can also refer to dose conversion for different animals. More
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Tetrahydrocoptisine 4312-32-7 MAPK NF-Κb NF-κB p38 MAPK ERK STYLOPINE inhibitor inhibit