Powder: -20°C for 3 years | In solvent: -80°C for 1 year
1. Ganoderic acid A exhibits antitumor activity, mediated through its inhibitory effect on nuclear transcription factor-kappaB and activator protein-1. 2. Ganoderic acid A can induce proliferation inhibition, apoptosis and suppression of invasion in human osteosarcoma HOS and MG-63 cells. 3. Ganoderic acid A promotes cisplatin-induced cell death by enhancing the sensitivity of HepG2 cells to cisplatin mainly via the signal transducer and activator of transcription 3 suppression, significantly suppresses IL-6-induced signal transducer and activator of transcription 3 phosphorylation.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 39.00 | |
5 mg | In stock | $ 98.00 | |
10 mg | In stock | $ 163.00 | |
25 mg | In stock | $ 263.00 | |
50 mg | In stock | $ 393.00 | |
100 mg | In stock | $ 576.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 112.00 |
Description | 1. Ganoderic acid A exhibits antitumor activity, mediated through its inhibitory effect on nuclear transcription factor-kappaB and activator protein-1. 2. Ganoderic acid A can induce proliferation inhibition, apoptosis and suppression of invasion in human osteosarcoma HOS and MG-63 cells. 3. Ganoderic acid A promotes cisplatin-induced cell death by enhancing the sensitivity of HepG2 cells to cisplatin mainly via the signal transducer and activator of transcription 3 suppression, significantly suppresses IL-6-induced signal transducer and activator of transcription 3 phosphorylation. |
Source |
Molecular Weight | 516.67 |
Formula | C30H44O7 |
CAS No. | 81907-62-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (96.77 mM)
You can also refer to dose conversion for different animals. More
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Ganoderic acid A 81907-62-2 Apoptosis Autophagy Metabolism NF-Κb NF-κB Endogenous Metabolite Inhibitor inhibit inhibitor