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Triptonide

Catalog No. T5S1058   CAS 38647-11-9
Synonyms: PG 492, NSC 165677

1. Triptonide (PG 492) is effective in the treatment of autoimmune diseases and has potent antileukemic and antitumor activities. 2. Triptonide possesses anti-inflammatory activity, upregulate the expression of IL-37, and this expression was suppressed by ERK1/2 and p38 MAPK inhibitors.

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Triptonide Chemical Structure
Triptonide, CAS 38647-11-9
Pack Size Availability Price/USD Quantity
1 mg In stock $ 51.00
5 mg In stock $ 116.00
10 mg In stock $ 169.00
25 mg In stock $ 297.00
50 mg In stock $ 523.00
100 mg In stock $ 759.00
1 mL * 10 mM (in DMSO) In stock $ 143.00
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Purity: 99.64%
Purity: 98.8%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description 1. Triptonide (PG 492) is effective in the treatment of autoimmune diseases and has potent antileukemic and antitumor activities. 2. Triptonide possesses anti-inflammatory activity, upregulate the expression of IL-37, and this expression was suppressed by ERK1/2 and p38 MAPK inhibitors.
Targets&IC50 Wnt:0.3 nM (IC50)
Source
Synonyms PG 492, NSC 165677
Molecular Weight 358.39
Formula C20H22O6
CAS No. 38647-11-9

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 50 mg/mL (139.51 mM)

TargetMolReferences and Literature

1. Pei R J , Qi L H , Liu X J . Effects of triptonide on mouse immune functions.[J]. Zhongguo Yao LI Xue Bao, 1993, 14(3):238-242.

Related compound libraries

This product is contained In the following compound libraries:
Anti-Cancer Drug Library Anti-Cancer Approved Drug Library Terpene Natural Product Library Neural Regeneration Compound Library Natural Product Library Approved Drug Library Anti-Aging Compound Library Osteogenesis Compound Library Anti-Prostate Cancer Compound Library Natural Product Library for HTS

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Keywords

Triptonide 38647-11-9 Apoptosis Autophagy Cytoskeletal Signaling Stem Cells Wnt/beta-catenin Tripterygium Beta catenin Inhibitor inhibit β-catenin ERK NSC165677 anti-cancer PG 492 NSC-165677 PG-492 Hook F. Lyn NSC 165677 wilfordii Wnt PG492 lymphoma inhibitor

 

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