store at low temperture,keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Sugiol (10-Deoxoxanthoperol) has antioxidant efficacy, it has significant scavenging activities of 1,1-diphenyl-2-picryl hydrazyl, nitric oxide, superoxide and hydroxyl free radicals. Sugiol's efficacy in inhibiting the inflammatory cytokines of IL-1beta and TNF-alpha could be attributed to a reduction of the ROS that leads to a decrease in the phosphorylation of MAPKs.
Description | Sugiol (10-Deoxoxanthoperol) has antioxidant efficacy, it has significant scavenging activities of 1,1-diphenyl-2-picryl hydrazyl, nitric oxide, superoxide and hydroxyl free radicals. Sugiol's efficacy in inhibiting the inflammatory cytokines of IL-1beta and TNF-alpha could be attributed to a reduction of the ROS that leads to a decrease in the phosphorylation of MAPKs. |
In vitro | An abietane type diterpenoid Sugiol, isolated from ethyl acetate extract of M. glyptostroboides cones, was analyzed for its antioxidant efficacy as reducing power ability and lipid peroxidation inhibition as well as its ability to scavenge free radicals such as 1,1-diphenyl-2-picryl hydrazyl, nitric oxide, superoxide and hydroxyl radicals. The Sugiol showed significant and concentration-dependent antioxidant and free radical scavenging activities. Consequently, the Sugiol exerted lipid peroxidation inhibitory effect by 76.5% as compared to α±-tocopherol (80.13%) and butylated hydroxyanisole (76.59%). In addition, the Sugiol had significant scavenging activities of 1,1-diphenyl-2-picryl hydrazyl, nitric oxide, superoxide and hydroxyl free radicals in a concentration-dependent manner by 78.83%, 72.42%, 72.99% and 85.04%, when compared to the standard compound ascorbic acid (81.69%, 74.62%, 73.00% and 73.79%) and α±-tocopherol/butylated hydroxyanisole (84.09%, 78.61%, 74.45% and 70.02%), respectively[1] |
Synonyms | 10-Deoxoxanthoperol |
Molecular Weight | 300.44 |
Formula | C20H28O2 |
CAS No. | 511-05-7 |
store at low temperture,keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Sugiol 511-05-7 Apoptosis Immunology/Inflammation IL Receptor TNF ROS 10-Deoxoxanthoperol inhibitor inhibit