Powder: -20°C for 3 years
In solvent: -80°C for 2 years
Tacrolimus hydrate is a macrolide from the culture broth of a strain of Streptomyces tsukubaensis, binds to FK506 binding protein (FKBP) to form a complex. Tacrolimus inhibits calcineurin phosphatase, which inhibits T-lymphocyte signal transduction and IL-2 transcription. Immunosuppressive properties. It prevents the activation of T-lymphocytes in response to antigenic or mitogenic stimulation in vitro and has strong immunosuppressive activity in vivo.
Description | Tacrolimus hydrate is a macrolide from the culture broth of a strain of Streptomyces tsukubaensis, binds to FK506 binding protein (FKBP) to form a complex. Tacrolimus inhibits calcineurin phosphatase, which inhibits T-lymphocyte signal transduction and IL-2 transcription. Immunosuppressive properties. It prevents the activation of T-lymphocytes in response to antigenic or mitogenic stimulation in vitro and has strong immunosuppressive activity in vivo. |
Synonyms | Tacrolimus hydrate, FK-506, LCP-Tacro, Prograf, FK 506, FR900506, FR 900506 |
Molecular Weight | 822.05 |
Formula | C44H71NO13 |
CAS No. | 109581-93-3 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
DMSO: 100 mg/mL (121.65 mM)
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
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Tacrolimus monohydrate 109581-93-3 Autophagy Metabolism Microbiology/Virology Others Antibiotic Phosphatase Antibacterial Tacrolimus hydrate Tacrolimus Inhibitor FR-900506 FK506 FK-506 LCP-Tacro Bacterial Prograf FK 506 FR900506 inhibit Fujimycin FK506-binding protein FR 900506 FKBP inhibitor