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IL-2 R gamma/CD132 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated

Catalog No. TMPK-00987
Synonyms: IL-2 R γ/CD132, IL-2 R gamma, IMD4, gammaC, SCIDX1, CD132, SCIDX, IL2RG, P64, IL-2 R γ, γC, CIDX

The gamma chain of the high affinity functional human IL-2 receptor complex belongs to the hematopoietin receptor family. IL-2 R gamma is a 369 amino acid residue protein consisting of a 22 residue signal sequence, a 232 residue extracellular domain, a 29 residue transmembrane domain and an 86 residue cytoplasmic domain. Although IL-2 R gamma by itself does not bind IL-2 with any appreciable affinity, it is required for IL-2 receptor signaling.

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IL-2 R gamma/CD132 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated
Pack Size Availability Price/USD Quantity
100 μg 5 days $ 814.00
500 μg 5 days $ 3,250.00
1 mg 5 days $ 5,440.00
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Biological Description
Technical Params
Product Properties
References and Literature
Description The gamma chain of the high affinity functional human IL-2 receptor complex belongs to the hematopoietin receptor family. IL-2 R gamma is a 369 amino acid residue protein consisting of a 22 residue signal sequence, a 232 residue extracellular domain, a 29 residue transmembrane domain and an 86 residue cytoplasmic domain. Although IL-2 R gamma by itself does not bind IL-2 with any appreciable affinity, it is required for IL-2 receptor signaling.
Species Cynomolgus
Expression System HEK293
Tag C-His
Accession Number Q38JL2
Synonyms IL-2 R γ/CD132, IL-2 R gamma, IMD4, gammaC, SCIDX1, CD132, SCIDX, IL2RG, P64, IL-2 R γ, γC, CIDX
Construction Recombinant Biotinylated Cynomolgus IL-2 R gamma/CD132 Protein (Primary Amine Labeling) is expressed from HEK293 with His tag at the C-Terminus. It contains Leu23-Asn254.[Accession |Q38JL2]
Protein Purity > 95% as determined by Tris-Bis PAGE
Molecular Weight The protein has a predicted MW of 28.2 kDa. Due to glycosylation, the protein migrates to 50-70 kDa based on Tris-Bis PAGE result.
Endotoxin Less than 1EU per μg by the LAL method.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability & Storage

-20 to -80°C for 12 months as supplied from date of receipt. -20 to -80°C for 3-6 months in unopened state after reconstitution. 2-8°C for 2-7 days after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.

Research Background The gamma chain of the high affinity functional human IL-2 receptor complex belongs to the hematopoietin receptor family. IL-2 R gamma is a 369 amino acid residue protein consisting of a 22 residue signal sequence, a 232 residue extracellular domain, a 29 residue transmembrane domain and an 86 residue cytoplasmic domain. Although IL-2 R gamma by itself does not bind IL-2 with any appreciable affinity, it is required for IL-2 receptor signaling.

References and Literature

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Keywords

IL-2 R gamma/CD132 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated P-64 IL-2 R γ/CD132 IMD 4 SCIDX 1 IL-2 R gamma P 64 IMD4 gammaC SCIDX1 CD-132 CD132 SCIDX-1 CD 132 IMD-4 SCIDX IL2RG P64 IL-2 R γ γC CIDX recombinant recombinant-proteins proteins protein

 

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