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Methylthiouracil

Catalog No. T0304 CAS 56-04-2

Synonyms: MTU, NSC-193526, 甲硫氧嘧啶, NSC-9378, 甲基硫脲嘧啶

Methylthiouracil is a thiourea antithyroid agent that inhibits the synthesis of thyroid hormone, and it is used to treat hyperthyroidism.

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Methylthiouracil, CAS 56-04-2

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Methylthiouracil is a thiourea antithyroid agent that inhibits the synthesis of thyroid hormone, and it is used to treat hyperthyroidism.
In vitro	Methylthiouracil acts to decrease the formation of stored thyroid hormone, as thyroglobulin in the thyroid gland. Methylthiouracil is also used in combination with radioactive iodine.

Synonyms	MTU, NSC-193526, 甲硫氧嘧啶, NSC-9378, 甲基硫脲嘧啶
Molecular Weight	142.18
Formula	C5H6N2OS
CAS No.	56-04-2

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

Ethanol: <1 mg/mL

DMSO: 27 mg/mL (189.9 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Crooks J, et al. Br Med J, 1960, 1(5167), 151-154. 2. Doniach I, et al. Br J Cancer, 1953, 7(2), 181-202.

Related compound libraries

This product is contained In the following compound libraries：

Anti-Cancer Compound Library HIF-1 Signaling Pathway Compound Library Anti-Cancer Metabolism Compound Library Endocrinology-Hormone Compound Library Glutamine Metabolism Compound Library Inhibitor Library Nucleotide Compound Library Immunology/Inflammation Compound Library Drug Repurposing Compound Library Anti-Cancer Approved Drug Library

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Methylthiouracil 56-04-2 MAPK信号通路 NF-Kb信号通路凋亡免疫与炎症 Antiviral ERK Interleukin NF-κB TNF Extracellular signal regulated kinases Nuclear factor-κB inhibit Tumor Necrosis Factor Receptor Inhibitor TNFR NSC-9378 TNF Receptor Nuclear factor-kappaB NSC-193526 Interleukin Related MTU inhibitor

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