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Cat No. | Product Name | Synonyms | Targets |
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T17311 | (+)-JQ1 PA | Epigenetic Reader Domain | |
(+)-JQ1 PA is a derivative of the Bromodomain and extra-terminal (BET) inhibitor JQ1(IC50 of 10.4 nM). | |||
T41005 | PA-8 | PACAP | |
PA-8 is a small molecule receptor antagonist for PACAP Type I (PAC1) that is selective, effective, and orally active. PA-8 inhibits PacAP-induced CREB phosphorylation at PAC1- receptors, but does not inhibit VPAC1- or vp... | |||
T15555 | IK1 inhibitor PA-6 | Potassium Channel | |
IK1 inhibitor PA-6 (PA-6) is a selective and potent inhibitor of IK1 (KIR2.x ion-channel-carried inward rectifier current)(IC50 of 12-15 nM for human and mouse KIR2.x currents). | |||
T24585 | PA-9 | PA 9 | |
PA-9 is the first small-molecule PAC1 receptor antagonist. | |||
T6096 | Pretomanid | (S)-PA 824,PA-824 | Antibacterial , Antibiotic |
Pretomanid ((S)-PA 824) , a nitroimidazole, is used as an anti-tuberculosis drug for tuberculosis with MIC less than 2.8 μM. | |||
T39209 | 5-PA-dUTP | 5-PA-dUTP,5-Propargylamino-dUTP | |
5-PA-dUTP (5-Propargylamino-dUTP) is a modified nucleotide, specifically designed with a C5 modification. It serves the purpose of being incorporated into DNA nanoparticles (DNPs) for the efficient delivery of photosensi... | |||
T39504 | PA Janelia Fluor® 646, SE | PA-JF646-NHS | |
PA Janelia Fluor 646, SE (PA-JF646-NHS), a photoactivatable fluorescent dye, is an NHS ester for coupling to primary amine groups. PA-JF646-NHS is non-fluorescent until activated at 365 nm. NHS ester can be converted to ... | |||
T33857 | PA Autoinducer | 3O-C12 autoinducer,PA-Autoinducer | |
PA Autoinducer is a Pseudomonas aeruginosa autoinducer. | |||
T68245 | PA-082 | ||
PA-082 is a Novel partial agonist of peroxisome proliferator-activated receptor-γ (PPARγ), recruiting PPARγ-coactivator-1α, preventing triglyceride accumulation, and potentiating insulin signaling in vitro. | |||
T39241 | PA Janelia Fluor® 549, SE | PA Janelia Fluor® 549, SE,PA-JF549-NHS | |
PA Janelia Fluor 549, SE (PA-JF549-NHS) is a bright photoactivatable fluorophore of JF549, SE (JF549, NHS). JF549, SE (JF549, NHS) is a fluorescent dye with the absorption maximum (λab (max)) of 549 nm and emission maxim... | |||
T41210 | PA Nic | ||
PA Nic is a coumarin-caged nicotine. Releases nicotine when exposed to 390 ± 10 nm wavelength light (λmax = 404 nm). Suitable for two-photon uncaging at <900 nm (Maximum two-photon cross-section at 810 nm). Extinction co... | |||
T22475 | 17-PA | Others | |
17-PA is a GABAA receptor antagonist. | |||
T33856 | PA 21 | PA21 | |
PA 21 is an iron-based noncalcium phosphate binder that prevents vascular calcification in chronic renal failure rats. | |||
T69261 | 2-Pmp-PA | ||
2-Pmp-PA is a taste modulator that inhibits sweetness. | |||
TP1867 | PA (224-233), Influenza | ||
PA (224-233), Influenza is a 10-aa peptide, which is a fragment of polymerase 2 protein in Influenza a virus. | |||
T17388 | AM-Imidazole-PA-Boc | Others | |
AM-Imidazole-PA-Boc is an alkyl chain-derived PROTAC linker utilized for the synthesis of PROTAC IRAK4 degrader-1[1]. | |||
T18252 | Mal-L-PA-NH-Boc | mDPR(boc) | Others |
Mal-L-PA-NH-Boc, a noncleavable ADC linker, facilitates the synthesis of antibody-drug conjugates (ADCs). | |||
T16425 | PA452 | Retinoid Receptor , RAR/RXR | |
PA452 is a selective antagonist of retinoic X receptor (RXR) and suppresses the effect of Retinoic acid on Th1/Th2 development. | |||
T79530 | SA-PA | PROTACs | |
SA-PA, a self-assembled intracellular PROTAC leveraging azide-alkyne click chemistry, selectively degrades VEGFR-2, PDGFR-β, and EphB4 proteins within U87 cells. In the presence of endogenous copper in tumor tissues, SA-... | |||
T2584L2 | Octreotide pamoate | SMS pa,SMS 201-995 pa | |
Octreotide pamoate is an antineoplastic agent. | |||
T34018 | Phenylalanyl adenylate | Phe-pA | |
Phenylalanyl adenylate is a bioactive chemical. | |||
T33866 | Palmitoyl alanine | N-Palmitoyl-L-alanine,Palmityl-L-alanine,Codeage PA | |
Palmitoyl alanine is a fatty acid. | |||
T83772 | 1-Linoleoyl Lysophosphatidic Acid sodium | 1-Linoleoyl-2-hydroxy-sn-glycero-3-PA,LPA(18:2),PA(18:2(9Z,12Z)/0:0),1-Octadecadienoyl-2-hydroxy-sn-glycero-3-phosphate,18:2 Lyso PA,1-Octadecadienoyl-2-hydroxy-sn-glycero-3-PA,PA(18:2/0:0),1-Linoleoyl-2-hydroxy-sn-glycero-3-phosphate,1-Linoleoyl LPA | |
1-Linoleoyl lysophosphatidic acid (1-linoleoyl LPA), a glycerophospholipid with linoleic acid at its sn-1 position, acts as an LPA2 receptor agonist and is the predominant LPA form in both mouse and human plasma. This co... | |||
T28287 | PA1 2HCl | PA1,PA1 dihydrochloride | |
PA1 2HCl is a blocker of photoswitchable epithelial sodium channel (ENaC). PA1 2HCl enables the optical control of ENaC channels, in particular the δβγ isoform, by switching between blue and green light, or by turning on... | |||
T0113 | Mebhydrolin napadisylate | Incidal,Diazolin,Mebhydroline 1,5-naphthalenedisulfonate salt,Omeril,Diazoline | 5-HT Receptor , AChR , Histamine Receptor |
Mebhydrolin napadisylate (Incidal) is an antihistamine used to relieve allergic symptoms caused by histamine release, including nasal allergies and allergic dermatosis. | |||
T22534 | 8-Hydroxy-DPAT hydrobromide | 8-OH-DPAT hydrobromide | 5-HT Receptor |
8-Hydroxy-DPAT hydrobromide (8-OH-DPAT hydrobromide) (8-OH-DPAT hydrobromide) is a potent and selective 5-HT1A agonist with a pIC50 of 8.19. 8-Hydroxy-DPAT hydrobromide has a selectivity of almost 1000 fold for a subtype... | |||
T39222 | Mc-VC-PAB-SN38 | Mc-VC-PAB-SN38 | Others |
Mc-VC-PAB-SN38 consists of a cleavable ADC linker (Mc-VC-PAB) and SN38, which is part of an antibody-coupled reactive molecule commonly used to synthesize antibody-coupled reactive molecules (ADCs) that target sites of a... | |||
T17266 | Xipamide | Diurexan,Aquaphor | Others |
Xipamide (Diurexan) is a sulfonamide-based diuretic with antihypertensive properties. Xipamide selectively inhibits anion exchanger. | |||
T12146 | N-Desmethyl-Apalutamide | N-Desmethyl Apalutamide | P450 , Androgen Receptor |
N-Desmethyl-Apalutamide is a less potent antagonist of the androgen receptor, is an active Apalutamide metabolite. | |||
T17877 | VH032-cyclopropane-F | VHL ligand 3,E3 ligase Ligand 19,Phenolic VH101 | Others , Ligand for E3 Ligase |
VH032-cyclopropane-F (Phenolic VH101) is a VH032-based VHL ligand. VH032-cyclopropane-F can be connected to the ligand for protein by a linker to form PROTACs. PROTAC 1 is a partial degrader of SMARCA2 and SMARCA4. | |||
T19399 | L-Ornithine L-aspartate | Ornithine Aspartate | Others |
L-Ornithine L-aspartate (Ornithine Aspartate) lowers blood ammonia concentration and to eliminate symptoms of hepatic encephalopathy associated with liver cirrhosis. | |||
T3353 | Niraparib hydrochloride | MK-4827 hydrochloride,MK-4827 (hydrochloride) | Apoptosis , Others , PARP |
Niraparib hydrochloride (MK-4827 hydrochloride) is an inhibitor of poly (ADP-ribose) polymerase (PARP) with potential antineoplastic activity. Niraparib hydrochloride inhibits PARP activity, enhancing the accumulation of... | |||
T6071 | Parbendazole | SKF 29044 | Microtubule Associated , Parasite |
Parbendazole (SKF 29044) is a potent inhibitor of microtubule assembly(EC50 : 8.79 nM).Parbendazole is a carbamate ester-amine. It finds applications in control or treatment of nematode infestations. | |||
T21907 | PACOCF3 | 1,1,1-trifluoroheptadecan-2-one,Palmityltrifluoromethylketone | Phospholipase |
PACOCF3 (Palmityltrifluoromethylketone) (Palmityltrifluoromet hylketone) is an inhibitor of Ca(2+)-independent phospholipase A2(PLA2) with an IC 50 of 3.8 μM. PACOCF3 alters Ca 2+ signaling in renal tubular cells [1] [2]... | |||
T23477 | Tris(dibenzylideneacetone)dipalladium | Tris DBA | Others |
tris(dibenzylideneacetone)dipalladium (Tris DBA) is a N-myristoyltransferase-1 (NMT-1) inhibitor | |||
T6358 | 1-Azakenpaullone | azakenpaullone | GSK-3 |
1-Azakenpaullone (azakenpaullone) is a potent and selective GSK-3β inhibitor with IC50 of 18 nM, >100-fold selectivity over CDK1/cyclin B and CDK5/p25. | |||
TP1042 | Palmitoyl Tetrapeptide-3 | Rigin | Others |
Palmitoyl Tetrapeptide-3 (Rigin) (Rigin) is a synthetic peptide, corrspending to 341-344 amino acid sequence of IgG human H-chain, with phagocytosis stimulating activity.Palmitoyl Tetrapeptide-3 stimulates expression of ... | |||
T76735 | Mupadolimab | CPI-006 | CD73 |
Mupadolimab (CPI-006) is a humanized FC-γR binding deficient IgG1 anti-CD73 antibody with potential anticancer activity and activation of CD73POS B cells. | |||
T76796 | Patritumab | U3-1287,AMG-888 | ERK , EGFR , Akt , HER |
Patritumab (U3-1287) is an anti-HER3 monoclonal antibody with potential antitumor activity and inhibits phosphorylation of EGFR, HER2, HER3, ERK, and AKT.Patritumab promotes apoptosis and inhibits proliferation in non-sm... | |||
T64335 | Boc-L-aspartic acid 4-benzyl ester | Boc-Asp(OBzl)-OH | Amino Acids and Derivatives |
Boc-L-aspartic acid 4-benzyl ester (Boc-Asp(OBzl)-OH) is an aspartic acid derivative. | |||
T26637 | Antipain dihydrochloride | Antipain 2HCl,BDBM-32804,BDBM 32804, Antipain,BDBM32804 | Protease |
Antipain dihydrochloride (Antipain 2HCl) is a protease inhibitor derived from Actinomycetes that exhibits analgesic activity and inhibits X-ray-induced chromosomal aberrations in human lymphocytes. | |||
T76756 | Parsatuzumab | RG 7414,Anti-EGFL7,MEGF0444A,MEGF-0444A,RO-5490248,M0444A | VEGFR |
Parsatuzumab (RG 7414) is a humanized monoclonal antibody targeting EGFL7, which is also used as an immunomodulator.Parsatuzumab selectively inhibits the interaction between EGFL7 and endothelial cells, and has an inhibi... | |||
T18867 | Val-Cit-PAB-MMAE | ||
Val-Cit-PAB-MMAE is a drug-linker conjugate for ADC. Val-Cit-PAB-MMAE contains the ADCs linker (peptide Val-Cit-PAB) and a potent tubulin inhibitor MMAE . MMAE a potent mitotic inhibitor by inhibiting tubulin polymerizat... | |||
T7767 | FMoc-Val-Cit-PAB-PNP | Others | |
Fmoc-Val-Cit-PAB-PNP is a linker for Antibody-Drug-Conjugation (ADC). | |||
T9445 | Vepafestinib | c-RET | |
Vepafestinib is a RET inhibitor with potential antineoplastic activity[1]. | |||
T78182 | PARP-1-IN-4 | Others , PARP | |
PARP-1-IN-4 is a potent PARP-1 inhibitor with potential see anti-tumor activity, and inhibition of PARP-1 may be used in cancer development. | |||
T81646 | NPAS3-IN-1 | Others | |
NPAS3-IN-1 is a potent inhibitor of NPAS3-ARNT heterodimerization, which regulates NPAS3 transcription by modulating the heterodimerization of NPAS3 with ARNT at the cellular level. | |||
T65796 | β-Methyl L-aspartate hydrochloride | L-Aspartic acid β-methyl ester hydrochloride,H-Asp(OMe)-OH.HCl | Amino Acids and Derivatives |
β-Methyl L-aspartate hydrochloride (L-Aspartic acid β-methyl ester hydrochloride) is an aspartic acid derivative commonly used to synthesize various compounds and is related to body immunity and metabolism. | |||
T11122 | DUPA(OtBu)-OH | Others | |
DUPA(OtBu)-OH is a DUPA precursor. DUPA is used as the targeting moiety to actively deliver Docetaxel (DTX) for treatment of Prostate-Specific Membrane Antigen (PSMA) expressing prostate cancer. PSMA has a high affinity ... | |||
T17256 | Wnt pathway activator 1 | Wnt/beta-catenin | |
Wnt pathway activator 1 is a potent Wnt activator with an IC50 of 28-29 nM. Wnt pathway activator 1 is a potent Wnt activator for the treatment of androgenetic alopecia (AGA). |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T5782 | Bevirimat | YK FH312,MPC-4326,PA-457 | HIV Protease |
Bevirimat (PA-457) is a first-in-class inhibitor of HIV-1 maturation, blocking the cleavage of the Gag capsid (CA) precursor, CA-SPI, to mature CA protein during virion maturation. | |||
T0469 | Octopamine hydrochloride | (±)-p-Octopamine hydrochlorid,(+,-)-Octopamine HCl | Dopamine Receptor , Endogenous Metabolite , Adrenergic Receptor |
Octopamine hydrochloride ((±)-p-Octopamine hydrochlorid) is a biogenic monoamine structurally associated with noradrenaline. It can serve as a neurohormone, a neurotransmitter, and a neuromodulator in invertebrates. | |||
T5243 | (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl ditetradecanoate | DMPE,1,2-Dihexadecanoyl-sn-glycero-3-phosphoethanolamine,1,2-Dimyristoyl-sn-glycero-3-PE | Others , Endogenous Metabolite |
(2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl ditetradecanoate (DMPE) is a phosphatidylethanolamine (PE or GPEtn). It is a glycerophospholipid in which a phosphorylethanolamine moiety occupies a glycer... | |||
T4950 | 1,2-Dipalmitoyl-sn-glycerol | (S)-1,2-Dipalmitin | Endogenous Metabolite , PKC |
1,2-Dipalmitoyl-sn-glycerol ((S)-1,2-Dipalmitin) is an analog of the PKC-activating second messenger diacylglycerol (DAG). It weakly activates PKC. | |||
T4875 | Palatinose hydrate | 6-O-α-D-Glucopyranosyl-D-fructose, Isoma | Others , Endogenous Metabolite |
Palatinose hydrate (6-O-α-D-Glucopyranosyl-D-fructose, Isoma) is a disaccharide having an α(1→6) linkage between D-glucose and D-fructose and is similar to sucrose in its physicochemical properties. It is produced from s... | |||
TN1698 | Glucotropaeolin potassium | Glucotropaeolin,Benzylglucosinolate potassium,Glucotropaeolin Potassium Salt | Others |
Glucotropaeolin potassium (Benzylglucosinolate potassium) is found in cruciferous vegetables and moderately decrease spontaneous DNA damage in animals. | |||
T5238 | 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine | 1,2-Dipalmitoyl-sn-glycero-3-PE,1,2-Dipalmitoyl-sn-glycerol-3-Phosphoethanolamine,1,2-DPPE | Others , Endogenous Metabolite |
1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine (DPPE), a phospholipid member of the glycerophosphonoethanolamine family, is a major component in biological membranes. Studies focused on interactions between DPPE and ch... | |||
T1104 | Paromomycin Sulfate | Aminosidine sulfate,Paromomycin sulfate salt | Antibacterial , Antibiotic , Parasite |
Paromomycin binds specifically to the RNA oligonucleotide at the A site of bacterial 30S ribosomes, thereby causing misreading and premature termination of translation of mRNA and inhibition of protein synthesis followed... | |||
TN2233 | Spathulenol | Antioxidant , Antifungal | |
Spathulenol is a natural ingredient from Aristolochia yunnanensis that has anti-inflammatory, antioxidant, anti-proliferation, anti-ulcer and anti-mycobacterium activities. Spathulenol showed significant antioxidant acti... | |||
T4885 | (-)-Aspartic acid | (R)-Aspartic acid,Asp,D-(-)-Aspartic acid,Aminosuccinic acid,asparagic acid,L-Homoproline,D-Aspartic acid | Endogenous Metabolite , NMDAR , iGluR |
(-)-Aspartic acid (L-Homoproline) is an endogenous amino acid existing in invertebrates and vertebrates. It can regulate testosterone synthesis and is an agonist of NMDA receptor. | |||
TQ0285 | Spaglumic acid | N-Acetylaspartylglutamic acid,NAAG | Endogenous Metabolite |
Spaglumic acid (N-Acetylaspartylglutamic acid) is a neuropeptide found in millimolar concentrations in the brain. | |||
T4773 | 3-Ethoxy-3-oxopropanoic acid | Monoethyl malonic acid,Ethyl hydrogen malonate | Others , Endogenous Metabolite |
3-Ethoxy-3-oxopropanoic acid (Monoethyl malonic acid) belongs to the class of organic compounds known as dicarboxylic acids and derivatives. These are organic compounds containing exactly two carboxylic acid groups. 3-Et... | |||
T38815 | Millepachine | Apoptosis | |
Millepachine is a natural product found in the Chinese herbal medicine with strong antitumor effects against numerous human cancer cells. | |||
T9218 | Andrograpanin | 19-HYDROXY-8(17),13-LABDADIEN-16,15-OLIDE | p38 MAPK |
Andrograpanin (19-HYDROXY-8(17),13-LABDADIEN-16,15-OLIDE) is a bioactive compound from Andrographis paniculata. Andrograpanin has anti-inflammatory and anti-infectious properties. | |||
T5749 | 10-Deacetyl-7-xylosyl paclitaxel | 10-Deacetyl-7-xylosyltaxol,10-Deacetyltaxol 7-Xyloside,7-Xylosyl-10-deacetyltaxol,10-Deacetylpaclitaxel 7-Xyloside | Others , Microtubule Associated |
10-Deacetyl-7-xylosyl paclitaxel (7-Xylosyl-10-deacetyltaxol) is a Paclitaxel derivative with improved pharmacological features and higher water solubility,used in Chinese clinics to treat cancer. | |||
T3S2105 | N-Benzylpalmitamide | Macamide 1,N-Benzylhexadecanamide | Others , FAAH , Autophagy |
N-Benzylpalmitamide (Macamide 1) inhibits fatty acid amide hydrolase (FAAH) in a time-dependent manner and could potentially offer a good alternative for the treatment of pain, inflammation and CNS degenerative disorders... | |||
TN1517 | 1-(2,6-dimethoxyphenyl)-3-(4-hydroxyphenyl)propan-1-one | Cochinchinenin A | Others |
1-(2,6-dimethoxyphenyl)-3-(4-hydroxyphenyl)propan-1-one (Cochinchinenin A) is the material basis for the analgesic effect of Dragons Blood. | |||
T3S1457 | Palmaturbine | Palmatrubin,Palmatrubine | Others |
Palmaturbine (Palmatrubine) shows high antitumor activity. | |||
T6S1780 | Protosappanin B | Q-100961,FT-0689654 | Apoptosis |
1. Protosappanin B (Q-100961) significantly increases cell viability, inhibits cell apoptosis and up-regulates the expression of growth-associated protein 43. 2. Protosappanin B induces the degradation of p53 protein, vi... | |||
T19500 | Palmitelaidic Acid | trans-Palmitoleic acid,9-trans-Hexadecenoic acid | Glucokinase , AMPK , PPAR |
Palmitelaidic Acid (trans-Palmitoleic acid) is one of the most abundant fatty acids in serum and tissue. | |||
T2O2731 | L-Aspartic acid | Aspatofort,Asparagic acid | Others , Endogenous Metabolite |
L-Aspartic acid (Aspatofort) is a non-essential amino acid in humans, L-Aspartic acid has an overall negative charge and plays an important role in the synthesis of other amino acids and in the citric acid and urea cycle... | |||
T3917 | Protopanaxatriol | 20(R)-APPT,20(R)-Protopanaxatriol,(20R)-Protopanaxatriol | PPAR |
Protopanaxatriol (20(R)-APPT), a major ginseng constituent, is a novel PPARγ antagonist. | |||
T6S2023 | Harpagoside | Others , COX , NO Synthase | |
1. Harpagoside has anti-inflammatory activity. 2. Harpagoside at 3 mM concentration, shows moderate inhibition of seed germination. 3. Harpagoside can inhibit lipopolysaccharide-induced mRNA levels and protein expression... | |||
TN2554 | 1-Monopalmitin | Glyceryl palmitate | Apoptosis |
1-Monopalmitin (Glyceryl palmitate) is a small molecule compound extracted from Mougeotia nummuloides and Spirulina major with potential antitumor activity, inhibiting proliferation of A549 and SPC-A1 cells, and inducing... | |||
TN1803 | Isoscoparin | Antioxidant , TNF , NO Synthase , Fatty Acid Synthase | |
Isoscoparin is derived from Gentiana algida Pall with antioxidant and anti-adipogenic activities. Isoscoparin can be used in stuides about the prevention and treatment of obesity. | |||
T32570 | Lappaconine | 20-ethyl-1,14,16-trimethoxyaconitane-4,6,8-triol,O(sup 1)-Methyllappaconidine | Others |
Lappaconine (20-ethyl-1,14,16-trimethoxyaconitane-4,6,8-triol) derivated from norditerpenoid alkaloids. | |||
T5284 | N-Carbamoyl-DL-aspartic acid | N-Carbamoyl-DL-aspartic acid,Ureidosuccinic acid | Others , Endogenous Metabolite |
N-Carbamoyl-DL-aspartic acid (Ureidosuccinic acid) is an intermediary product in pyrimidine biosynthesis. | |||
TN1005 | Parishin E | Others | |
Parishin E is a natural product from Gastrodia elata,have antioxidant property. | |||
T5739 | Paederosidic acid | Apoptosis , BCL | |
Paederosidic acid has significant anti-tumor, anticonvulsant and sedative effects. Paederosidic acid increases brain gamma-aminobutyric acid and decreases glutamic acid in the brain, and it up-regulates expressions of GA... | |||
TN7246 | 3-Sulfopropanoic acid | 3-SPA | Drug Metabolite |
3-Sulfopropanoic acid, a major metabolite of treprostinil and its prodrug ALZ-801, is an endogenous molecule present in the cerebrospinal fluid (CSF) of AD patients that inhibits the formation of Aβ42 oligomers. | |||
TN1067 | Galloylpaeoniflorin | 6'-O-Galloyl paeoniflorin | NF-κB , Androgen Receptor , ROS |
Galloylpaeoniflorin (6'-O-Galloyl paeoniflorin) may be developed as a cytoprotector against ROS-mediated oxidative stress. Galloylpaeoniflorin is also an inhibtior of NF-κB and DNA cleavage. | |||
T0345 | Estropipate | Piperazine estrone sulfate,Pipestrone,Estrone sulfate piperazine salt | Estrogen Receptor/ERR , Estrogen/progestogen Receptor |
Estropipate (Piperazine estrone sulfate) is a natural estrogenic substance composed of estrone sulfate and piperazine. | |||
T2793 | Tetrahydropalmatine | DL-Tetrahydropalmatine,Rotundine | Apoptosis , Others , Dopamine Receptor |
Tetrahydropalmatine (DL-Tetrahydropalmatine) is an active component isolated from corydalis, suppressing amygdaloid release of dopamine to inhibit an epileptic attack in rats. | |||
T4S0779 | D-tetrahydropalmatine | Others , Dopamine Receptor | |
D-Tetrahydropalmatine is a organic cation transporter 1 (OCT1) inhibitor, it can obviously inhibit the uptake of monocrotaline (MCT) in MDCK-hOCT1 cells and isolate rat primary hepatocytes, and attenuate the viability re... | |||
T2825 | Cyclopamine | 11-Deoxojervine | Hedgehog/Smoothened , Endogenous Metabolite , Smo |
Cyclopamine (11-Deoxojervine), a Smoothened (Smo) antagonist (IC50: 46 nM in TM3Hh12 cells), belongs to the group of steroidal jerveratrum alkaloids. | |||
T5S0802 | Palmatine | Berbericinine,Burasaine | Indoleamine 2,3-Dioxygenase (IDO) , AChR , AChE , Aurora Kinase |
1. Palmatine (Burasaine) is an inhibitor of dopamine generation. 2. Palmatine could potentially be developed for the treatment of flavivirus infections. 3. Palmatine has been used in the treatment of jaundice, dysentery,... | |||
T2900 | Paeonol | Peonol | MAO , Autophagy , Monoamine Oxidase |
Paeonol (Peonol) is an active extraction from Paeonia suffruticosa. Paeonol inhibits MAO-A and MAO-B with IC50 of 54.6 μM and 42.5 μM, respectively. | |||
TN6745 | PALATINOSE | TNP-470,Isomaltulose | Others |
PALATINOSE (TNP-470) is a natural occurring disaccharide composed of alpha-1,6-linked glucose and fructose。 PALATINOSE has a beneficial effect on liver metabolic functions and might therefore be a good substitute for suc... | |||
T2O2774 | L-Asparagine | alpha-aminosuccinamic acid,(-)-Asparagine,Asparamide,2-Aminosuccinamic acid,Asn,Altheine | Endogenous Metabolite |
L-Asparagine (Asparamide) is a non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue. It is biosynthesized from ASPARTIC ACID and AMMONIA by asparagine synthetase. | |||
T2916 | Patchouli alcohol | Patchouli camphor,Patchoulol,(-)-Patchouli Alcohol | Antibacterial , Antifungal |
Patchouli alcohol (Patchoulol) is a sesquiterpene alcohol found in patchouli oil. It has antibacterial, antifungal, and antiviral actions. Patchouli alcohol also suppresses inflammation induced by lipopolysaccharide in v... | |||
T6S2024 | Harpagide | Antibacterial , Parasite | |
1. Harpagide has antibacterial activity. 2. Harpagide has antiviral activity. 3. Harpagide has anti-inflammatory activity. | |||
T65269 | L-Aspartic acid potasium salt | Aspartic acid potasium salt,Potassium L-aspartate | Others |
L-aspartic acid potasium salt(VX-548) is an amino acid widely found in plants and animals.L-aspartic acid potasium salt drives the production of nitrogen oxides, which promotes phagocytosis and contributes to fish surviv... | |||
T0927 | Butylparaben | Butyl 4-hydroxybenzoate,Butyl parahydroxybenzoate | Endogenous Metabolite , Antibacterial , Antibiotic |
Butylparaben (Butyl 4-hydroxybenzoate) is a standardized chemical allergen, increasing histamine release, and cell-mediated immunity. | |||
T0505 | Methyldopa | L-(-)-α-Methyldopa,MK-351 | Dopamine Receptor , Adrenergic Receptor |
Methyldopa (MK-351), an alpha-adrenergic agonist (selective for α2-adrenergic receptors) psychoactive medicine, is served as an antihypertensive or sympatholytic. | |||
T3362 | Eupatilin | NSC 122413 | PPAR , Autophagy |
Eupatilin (NSC-122413), a flavone derived from Artemisia princepsPampanini, is a PPARα agonist, with pharmacological activity. | |||
T7113 | Paradol | 6-paradol,[6]-Gingerone | COX |
Paradol ([6]-Gingerone) is a pungent phenolic substance found in ginger and other Zingiberaceae plants, and exhibits a variety of biological activities including anti-cancer, anti-inflammatory, and anti-oxidative activit... | |||
T0978 | Pantethine | LBF disulfide,Pantosin,Pantetina,Bis-pantethine,Pantomin,D-Pantethine | Endogenous Metabolite |
Pantethine (Pantomin) (Bis-pantethine) is a dimeric form of vitamin B5. Pantethine is less stable than pantothenic acid and tends to decompose over time if it is not kept refrigerated, so most vitamin B5 supplements are ... | |||
TN2043 | Pasakbumin B | 13-alpha-(21)-Epoxyeurycomanone | Others |
Pasakbumin B (13-alpha-(21)-Epoxyeurycomanone) is a bioactive compound from Eurycoma longifolia Jack. | |||
T4S0794 | (R)-(+)-Corypalmine | Corypalmine,(+)-Corypalmine | Others |
1. (R)-(+)-Corypalmine ((+)-Corypalmine) shows strong papaverine-like activity. | |||
T9513 | Methyl 3-phenylpropanoate | 3-Phenylpropionic acid methyl ester | Endogenous Metabolite |
Methyl 3-phenylpropanoate (3-Phenylpropionic acid methyl ester) is a huamn endogenous metabolite. | |||
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Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPK-00782 | PLAU/uPA Protein, Mouse, Recombinant (His & Avi) | Mouse | HEK293 Cells |
Plasminogen activator, urokinase (uPA) is a secreted serine protease whose Dysregulation is often accompanied by various cancers. PLAU inhibition could suppress tumor growth. Collectively, PLAU is necessary for tumor pro... | |||
TMPY-00904 | Urokinase/uPA Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Urokinase/uPA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46 kDa and the accession number is A0A024QZM9. | |||
TMPY-00938 | TPA Protein, Human, Recombinant | Human | HEK293 Cells |
tPA Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 28 kDa and the accession number is P00750-1. | |||
TMPK-00810 | TPA Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Tissue plasminogen activator (tPA) is the predominant plasminogen activator present in the vascular and nervous systems.t tPA is not only neuroprotective for postnatal primary cortical neurons, but also that the predomin... | |||
TMPY-00937 | TPA Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
tPA Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 57.5 kDa and the accession number is P00750-1. | |||
TMPJ-00332 | TPA Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Tissue-type plasminogen activator (PLAT) is a protein that secreted into extracellular space. PLAT contains five domains: EGF-like domain, fibronectin type-I domain, 2 kringle domains and peptidase S1 domain. It belongs... | |||
TMPK-00539 | PLAU/uPA Protein (active form), Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
Plasminogen activator, urokinase (uPA) is a secreted serine protease whose Dysregulation is often accompanied by various cancers. PLAU inhibition could suppress tumor growth. Collectively, PLAU is necessary for tumor pro... | |||
TMPK-00274 | PLAU/uPA Protein (active form), Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
Plasminogen activator, urokinase (uPA) is a secreted serine protease whose Dysregulation is often accompanied by various cancers. PLAU inhibition could suppress tumor growth. Collectively, PLAU is necessary for tumor pro... | |||
TMPK-00783 | PLAU/uPA Protein, Mouse, Recombinant (His & Avi), Biotinylated | Mouse | HEK293 Cells |
Plasminogen activator, urokinase (uPA) is a secreted serine protease whose Dysregulation is often accompanied by various cancers. PLAU inhibition could suppress tumor growth. Collectively, PLAU is necessary for tumor pro... | |||
TMPY-03107 | Alpha amylase/AMY2A Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Alpha amylase/AMY2A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.3 kDa and the accession number is P04746. | |||
TMPY-02174 | FABP5 Protein, Human, Recombinant | Human | E. coli |
Fatty acid-binding protein, also known as Epidermal-type fatty acid-binding protein, Fatty acid-binding protein 5, Psoriasis-associated fatty acid-binding protein homolog, E-FABP and FABP5, is a cytoplasm protein whic... | |||
TMPH-00556 | 1-AGPAT Protein, E. coli, Recombinant (His) | E. coli | P. pastoris (Yeast) |
Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the 2 position. This enzyme can utilize either acyl-CoA or acyl-ACP as the fatty acyl donor. 1-AGPAT Protein, E. coli, Recomb... | |||
TMPJ-01073 | FABP5 Protein, Human, Recombinant (His) | Human | E. coli |
Fatty acid-binding protein 5 (FABP5) is a cytoplasm protein that belongs to the fatty-acid binding protein (FABP) family of calycin superfamily. Fatty acid binding proteins are a family of small, highly conserved, cytopl... | |||
TMPY-01188 | PARP Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
PARP Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 114.5 kDa and the accession number is A0A024R3T8. | |||
TMPY-02575 | PPAR gamma/PPARG Protein, Human, Recombinant (His & GST) | Human | Baculovirus Insect Cells |
Peroxisome proliferator-activated receptor gamma (PPARG), a nuclear hormone receptor, plays a critical role in the lipid and glucose homeostasis, adipocyte differentiation, as well as intracellular insulin-signaling even... | |||
TMPY-04180 | PfLDH Protein, P. falciparum, Recombinant (His) | P. falciparum | E. coli |
Plasmodium falciparum lactate dehydrogenase (PfLDH) is a key enzyme for energy generation of malarial parasites and is considered to be a potential antimalarial target. The ability of PfLDH- or PfIDEh-based immuno-PCR as... | |||
TMPH-03765 | Virus-Like Particles (VLPs) isotype control | ||
TMPY-01257 | UPAR/PLAUR Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
uPAR/PLAUR Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.4 kDa and the accession number is P35456-1. | |||
TMPY-05822 | Hepatitis B Virus (HBV)(ayw/France/Tiollais/1979) Capsid protein (His) | HBV-D | E. coli |
Hepatitis B virus (HBV) capsid assembly is a critical step in the propagation of the virus and is mediated by the core protein. The first cytoplasmic step in the formation of an infectious HBV virion is the formation of ... | |||
TMPY-03564 | TSPAN8 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
TSPAN8 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 13.4 kDa and the accession number is P19075. | |||
TMPY-01474 | PAI-1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
PAI-1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 44.2 kDa and the accession number is A0A024QYT5. | |||
TMPY-00021 | PADI4 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
Protein-arginine deiminase type-4, also known as HL-6 PAD, Peptidylarginine deiminase IV, Protein-arginine deiminase type I V and PADI4, is a cytoplasm and nucleus protein that belongs to the protein arginine deiminase f... | |||
TMPY-02707 | PAH Protein, Human, Recombinant (415 Asn/Asp, His) | Human | Baculovirus Insect Cells |
PAH (phenylalanine hydroxylase), also known as PH, belongs to the biopterin-dependent aromatic amino acid hydroxylase family. It contains 1 ACT domain, N-terminal region of PAH is thought to contain allosteric binding si... | |||
TMPY-02141 | UPAR/PLAUR Protein, Human, Recombinant (His) | Human | HEK293 Cells |
uPAR/PLAUR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.8 kDa and the accession number is Q03405-1. | |||
TMPY-00392 | PAM Protein, Human, Recombinant (His) | Human | HEK293 Cells |
PAM Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 94.4 kDa and the accession number is P19021-2. | |||
TMPK-00216 | UPAR/PLAUR Protein, Mouse, Recombinant (His & Avi), Biotinylated | Mouse | HEK293 Cells |
The receptor (u-PAR) for urokinase plasminogen activator (u-PA) is a three-domain protein, GPI-anchored to the cell surface, which focuses the enzymatic activity of u-PA, and allows the cell surface activation of plasmin... | |||
TMPK-00227 | UPAR/PLAUR Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
The receptor (u-PAR) for urokinase plasminogen activator (u-PA) is a three-domain protein, GPI-anchored to the cell surface, which focuses the enzymatic activity of u-PA, and allows the cell surface activation of plasmin... | |||
TMPK-01175 | UPAR/PLAUR Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
The receptor (u-PAR) for urokinase plasminogen activator (u-PA) is a three-domain protein, GPI-anchored to the cell surface, which focuses the enzymatic activity of u-PA, and allows the cell surface activation of plasmin... | |||
TMPK-00226 | UPAR/PLAUR Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
The receptor (u-PAR) for urokinase plasminogen activator (u-PA) is a three-domain protein, GPI-anchored to the cell surface, which focuses the enzymatic activity of u-PA, and allows the cell surface activation of plasmin... | |||
TMPK-00215 | UPAR/PLAUR isoform 1 Protein, Mouse, Recombinant (His & Avi) | Mouse | HEK293 Cells |
The receptor (u-PAR) for urokinase plasminogen activator (u-PA) is a three-domain protein, GPI-anchored to the cell surface, which focuses the enzymatic activity of u-PA, and allows the cell surface activation of plasmin... | |||
TMPK-00228 | UPAR/PLAUR Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
The receptor (u-PAR) for urokinase plasminogen activator (u-PA) is a three-domain protein, GPI-anchored to the cell surface, which focuses the enzymatic activity of u-PA, and allows the cell surface activation of plasmin... | |||
TMPH-03397 | UPAR/PLAUR Protein, Rat, Recombinant (His) | Rat | E. coli |
Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. uPAR/PLAUR Protein,... | |||
TMPY-01824 | Caspase-14 Protein, Human, Recombinant (His) | Human | E. coli |
Caspase 14 is a member of the caspase family. Caspases are a kind of cysteine proteinase consisting of a prodomain plus large and small catalytic subunits, that play a central role in cell apoptosis. Caspase 14 possesses... | |||
TMPY-02043 | PARK7/DJ-1 Protein, Human, Recombinant (His) | Human | E. coli |
Parkinson's disease locus DJ-1 (PARK7) is a differentially expressed transcript. DJ-1 plays a physiologic role in protection of erythroid cells from oxidant damage, a function unmasked in the context of oxidative stress.... | |||
TMPY-06739 | Pol d 5 Protein, Mediterranean paper wasp, Recombinant | Mediterranean paper wasp | P. pastoris (Yeast) |
Pol d 5 Protein, Mediterranean paper wasp, Recombinant is expressed in P. pastoris yeast expression system. The predicted molecular weight is 20 kDa. | |||
TMPH-01943 | PARP4 Protein, Human, Recombinant (His) | Human | E. coli |
PARP4 Protein, Human, Recombinant (His) is expressed in E. coli. | |||
TMPH-01883 | PARN Protein, Human, Recombinant (His) | Human | E. coli |
PARN Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 77.5 kDa and the accession number is O95453. | |||
TMPH-03141 | Plasmepsin-2 Protein, Plasmodium falciparum, Recombinant (His & Myc) | Plasmodium falciparum | Baculovirus Insect Cells |
During the asexual blood stage, participates in initial cleavage of native host hemoglobin (Hb) resulting in Hb denaturation. May cleave preferentially denatured hemoglobin that has been cleaved by PMI. Digestion of host... | |||
TMPH-02092 | PAK5 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
N/A. PAK5 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with N-6xHis tag. The predicted molecular weight is 34.9 kDa and the accession number is Q8TB93. | |||
TMPH-01898 | PARL Protein, Human, Recombinant (Myc) | Human | E. coli |
Required for the control of apoptosis during postnatal growth. Essential for proteolytic processing of an antiapoptotic form of OPA1 which prevents the release of mitochondrial cytochrome c in response to intrinsic apopt... | |||
TMPH-02833 | PAI-1 Protein, Mouse, Recombinant (His) | Mouse | P. pastoris (Yeast) |
PAI-1 Protein, Mouse, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 44.9 kDa and the accession number is P22777. | |||
TMPH-00509 | Protein-L-isoaspartate Protein, Drosophila melanogaster, Recombinant (His & Myc) | Fruit fly | E. coli |
Initiates the repair of damaged proteins by catalyzing methyl esterification of L-isoaspartyl and D-aspartyl residues produced by spontaneous isomerization and racemization of L-aspartyl and L-asparaginyl residues in agi... | |||
TMPH-01843 | Human parainfluenza 4b virus (HPIV-4b) Nucleoprotein/NP Protein (His) | HPIV-4b | E. coli |
Encapsidates the genome, protecting it from nucleases. The nucleocapsid (NC) has a helical structure. The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication. During replica... | |||
TMPH-03154 | Lys-gingipain 381 Protein, Porphyromonas gingivalis, Recombinant (His) | Porphyromonas gingivalis | E. coli |
Cysteine proteinase with a strong preference for substrates with Lys in the P1 position. Hydrolyzes bovine hemoglobin, bovine serum albumin, casein, human placental type I collagen and human IgA and IgG. Disrupts the fun... | |||
TMPH-01832 | Human Papilloma Virus type 16 (HPV 16) Protein E6 (E. coli, His) | HPV 16 | E. coli |
Human Papilloma Virus type 16 (HPV 16) Protein E6 (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 23.2 kDa and the accession number is P03126. | |||
TMPH-03077 | CGTases Protein, Paenibacillus macerans, Recombinant (E. coli, His) | Paenibacillus macerans | E. coli |
N/A. CGTases Protein, Paenibacillus macerans, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 15.4 kDa and the accession number is P31835. | |||
TMPH-03153 | Gingipain R2 Protein, Porphyromonas gingivalis, Recombinant (His) | Porphyromonas gingivalis | E. coli |
Thiol protease. Acts synergistically with RgpA to catalyze the maturation of fimbrial subunits, such as FimA. Its proteolytic activity is a major factor in both periodontal tissue destruction and in evasion of host defen... | |||
TMPK-00657 | SPARC Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
Secreted protein acidic and rich in cysteine (SPARC/osteonectin/BM40) is one of the most abundant non-collagenous protein expressed in mineralized tissues.The capacity of SPARC to influence pathways involved in extracell... | |||
TMPH-00294 | PAG-1 Protein, Bovine, Recombinant (His & SUMOstar) | Bovine | P. pastoris (Yeast) |
Appears to be proteolytically inactive. PAG-1 Protein, Bovine, Recombinant (His & SUMOstar) is expressed in yeast with N-6xHis-sumostar tag. The predicted molecular weight is 49.8 kDa and the accession number is Q29432. | |||
TMPH-00296 | Pregnancy-associated protein bPAP Protein, Bovine, Recombinant (His & Myc) | Bovine | E. coli |
Pregnancy-associated protein bPAP Protein, Bovine, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 17.3 kDa and the accession number is P84... | |||
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Cat No. | Product Name | ||
---|---|---|---|
VM1400 | Diversity Core Library Part2 | 25920 compounds | |
L1310 | Cytoskeletal Signaling Pathway Compound Library | 759 compounds | |
A unique collection of 759 cytoskeleton-related compounds, can be used for HTS and HCS; | |||
L2192 | Anti-Pancreatic Cancer Compound Library | 2238 compounds | |
A unique collection of 2238 pancreatic cancer related compounds can be used in HTS and HCS; | |||
L9830 | Anti-Parkinson's Disease Compound Library | 857 compounds | |
A unique collection of 857 compounds with anti-PD activities or acting on main drug targets of PD can be used for HTS and HCS. | |||
L6620 | Antiparasitic Natural Product Library | 253 compounds | |
A unique collection of 253 natural products with antiparasitic activity, a powerful tool for high throughput screening (HTS) and high content screening (HCS); | |||
L3900 | DNA Damage & Repair Compound Library | 910 compounds | |
A unique collection of 910 DNA Damage & Repair related compounds for high throughput screening (HTS) and high content screening (HCS); | |||
DF4500 | Diversity Core Library Part1 | 50000 compounds | |
L3980 | DNA Damage and Repair Compound Library Plus | 667 compounds | |
Well-chosen 667 compounds with unique structures targeting DNA damage & repair; | |||
L4020 | NO PAINS Compound Library | 9384 compounds | |
TargetMol created the L4020 NO-PAINS Compound Library that applied the PAINS filter, remaining 9384 small molecules that are suitable for new drug development, signaling pathway research, drug repurposing and other resea... | |||
L4510 | Anti-Parasitic Compound Library | 419 compounds | |
419 well-chosen unique anti-parasitic small molecules; | |||
L8500 | HIF-1 Signaling Pathway Compound Library | 1336 compounds | |
A unique collection of 1336 HIF-1 related small chemicals can be used for drug discovery in ischemic disease and cancer and related mechanism studies; |