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Andrograpanin

Catalog No. T9218 CAS 82209-74-3

Synonyms: 19-HYDROXY-8(17),13-LABDADIEN-16,15-OLIDE

Andrograpanin (19-HYDROXY-8(17),13-LABDADIEN-16,15-OLIDE) is a bioactive compound from Andrographis paniculata. Andrograpanin has anti-inflammatory and anti-infectious properties.

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Andrograpanin, CAS 82209-74-3

Pack Size	Availability	Price/USD
1 mg	In stock	$ 98.00
5 mg	In stock	$ 249.00
10 mg	In stock	$ 369.00
25 mg	In stock	$ 619.00
50 mg	In stock	Inquiry
1 mL * 10 mM (in DMSO)	In stock	$ 294.00

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Purity: 99.03%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Andrograpanin (19-HYDROXY-8(17),13-LABDADIEN-16,15-OLIDE) is a bioactive compound from Andrographis paniculata. Andrograpanin has anti-inflammatory and anti-infectious properties.
In vitro	Andrograpanin boosts the movement of leukocytes towards higher concentrations of the chemokine SDF-1α in Jurkat, THP-1, and PBL cells[1], demonstrating its ability to enhance chemotaxis. Additionally, it exhibits anti-inflammatory effects by inhibiting the p38 MAPKs signaling pathways in macrophage cells stimulated with lipopolysaccharide[2].

Synonyms	19-HYDROXY-8(17),13-LABDADIEN-16,15-OLIDE
Molecular Weight	318.45
Formula	C20H30O3
CAS No.	82209-74-3

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 55 mg/ml (172.71 mM)

References and Literature

1. Liu J , Wang Z T , Ge B X . Andrograpanin, isolated from Andrographis paniculata, exhibits anti-inflammatory property in lipopolysaccharide-induced macrophage cells through down-regulating the p38 MAPKs signaling pathways[J]. International Immunopharmacology, 2008, 8(7):951-958. 2. Andrograpanin, a compound isolated from anti‐inflammatory traditional Chinese medicine Andrographis paniculata, enhances chemokine SDF‐1α‐induced leukocytes chemotaxis[J]. Journal of Cellular Biochemistry, 2005, 95(5).

Related compound libraries

This product is contained In the following compound libraries：

Kinase Inhibitor Library Traditional Chinese Medicine Monomer Library Anti-Obesity Compound Library RO5 Drug-like Natural Product Library Anti-Cancer Compound Library Anti-Inflammatory Traditional Chinese Medicine Compound Library MAPK Inhibitor Library Bioactive Compound Library Neural Regeneration Compound Library Anti-Tumor Natural Product Library

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Keywords

Andrograpanin 82209-74-3 MAPK p38 MAPK Inhibitor chemotaxis 19-HYDROXY-8(17),13-LABDADIEN-16,15-OLIDE leukocyte SDF-1α PBL inhibit Jurkat anti-inflammatory THP-1 inhibitor

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