Search Result

Search Results for " tnf-a "

Targets

TNF

234

Compounds

Natural Products

261

Recombinant Proteins

Libraries

Cat No.	Product Name	Synonyms	Targets
T77494	TNF-α-IN-9		TNF
	TNF-α-IN-9 is an NDM-1 inhibitor-3 analog and is a TNF-α inhibitor.TNF-α-IN-9 shows low inhibitory activity.		TNF
T4637	R-7050	TNF-α Antagonist III	TNF
	R-7050 (TNF-α Antagonist III), a tumor necrosis factor receptor (TNFR) antagonist, exhibits heightened selectivity for TNFα.		TNF
T19584L	TNF-α (31-45), human acetate	TNF-α (31-45), human acetate(144796-71-4 free base)	Others
	TNF-α (31-45), human acetate is a peptide of tumor necrosis factor-α.		Others
T36127	TNF-α Antagonist
	TNF-α antagonist is an exocyclic peptide that mimics the critical TNF-α recognition loop on TNF receptor I complex and, thus, prevents ligand interaction with the receptor. By blocking the TNF receptor ligand contact sit...
T40321	TNF-α-IN-6
	TNF-α-IN-6 is an orally efficacious allosteric inhibitor of TNFα ( K D = 6.8 nM).
TP1626	TNF-α (46-65), human
	Human TNF alpha (46-65) peptide.
T21445	Naphazoline	AK-Con,Naphcon-a,Clear Eyes,All Clear	Adrenergic Receptor
	Naphazoline (Naphcon-a) is a sympathomimetic compound with marked alpha adrenergic activity. Naphazoline can be used as a vasoconstrictor with a rapid action in reducing swelling when applied to mucous membrane.		Adrenergic Receptor
T13175	TNF-α-IN-1		TNF
	TNF-α-IN-1 is a TNF-α inhibitor.		TNF
T19584	TNF-α (31-45), human		Others
	TNF-α (31-45), human is a peptide of tumor necrosis factor-α.		Others
T36097	TNF-α-IN-2
	TNF-α-IN-2 is a highly potent and orally bioavailable inhibitor of tumor necrosis factor alpha (TNFα), exhibiting an IC50 of 25 nM in the HTRF assay. It exerts its inhibitory effects by inducing conformational changes in...
TP1537	TNF-α (10-36), human
	TNF-α (10-36), human is a potent pro-inflammatory cytokine involved in the acute phase stress response.
TP1479	TNF-α (10-36), human (TFA) (144796-70-3 free base)	TNF-α (10-36), human (TFA)
	TNF-α (10-36), human (TFA) is a peptide of human TNF-α.
TP1636	TNF-α (31-45), human TFA (144796-71-4 free base)	TNF-α (31-45), human TFA
	TNF-α (31-45), human (TFA) is a peptide of tumor necrosis factor-α.
TP1669	TNF-α (46-65), human TFA (144796-72-5 free base)	TNF-α (46-65), human TFA
	TNF-α (46-65), human (TFA) is a peptide of human TNF-α.
T12985	SPD304 dihydrochloride		TNF
	SPD304 dihydrochloride is a selective inhibitor of TNF-α with an IC50 of 22 µM. SPD304 dihydrochloride promotes dissociation of TNF trimers.		TNF
T14848	C 87		Others , TNF
	C 87 is a small-molecule TNF-α inhibitor. C 87 directly binds to TNFα, potently inhibits TNF-α-induced cytotoxicity (IC50 = 8.73 μM), and effectively blocks TNF-α-triggered signaling activities.		Others , TNF
T37445	Etanercept		TNF
	Etanercept is a dimeric fusion protein that serves as a competitive TNF inhibitor by binding to TNF. It effectively inhibits the binding of both TNF-α and TNF-β to the TNF receptors on cell surfaces, thereby rendering TN...		TNF
T30531	BMS-561392	DPC333,DPC 333,DPC-333,BMS561392,BMS 561392	TNF
	BMS-561392 (DPC333) is a tumor necrosis factor-α ( TNF-α) Invertase inhibitor.		TNF
T83628	TNF/IFNγ-IN-1		Antioxidant , TNF , COX
	TNF/IFNγ-IN-1 (TGA) is a dual inhibitor of TNF and IFN-γ. TNF/IFNγ-IN-1 has potential antioxidant and anti-inflammatory activities for neurodegenerative diseases such as Alzheimer.		Antioxidant , TNF , COX
T9840	Ataquimas		Immunology/Inflammation related
	Ataquimast inhibits IL-5 secretion along with that of TNF-a, IL-4 and GM-CSF from human cells.		Immunology/Inflammation related
T21853	(E)-AG 556		EGFR
	AG 556 is a selective inhibitor of EGFR and blocks LPS-induced TNF-α production.		EGFR
T8845	UTL-5g	3-Isoxazolecarboxamide, N-(2,4-dichlorophenyl)-5-methyl-,GBL-5g	TNF
	UTL-5g (3-Isoxazolecarboxamide, N-(2,4-dichlorophenyl)-5-methyl-) is a novel potential chemoprotective agent, TNF-α inhibitor that reduces cisplatin-induced side effects including nephrotoxicity, hepatotoxicity and hemat...		TNF
T71691	Pumafentrine	BY 343	PDE
	Pumafentrine（BY 343） is a dual PDE3/PDE4 inhibitor that reduces clinical scores and TNF expression in experimental colitis in mice.		PDE
T60124	1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(7-(1-methyl-1H-pyrazol-4-yl)-2,3,4,9-tetrahydro-1H-carbazol-3-yl)urea		TNF
	1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(7-(1-methyl-1H-pyrazol-4-yl)-2,3,4,9-tetrahydro-1H-carbazol-3-yl)urea, a TNF-α agonistic compound, could induce cells to secrete TNF- α.		TNF
T8692	(Rac)-Benpyrine		TNF
	(Rac)-Benpyrine is a potent and orally active inhibitor of TNF-α.		TNF
T64349	Necroptosis-IN-3	Cyclohexanecarboxamide, N-(2-thienylmethyl)-	Necroptosis
	Necroptosis-IN-3 (Cyclohexanecarboxamide, N-(2-thienylmethyl)-) (Compound 69) is a Necroptosis inhibitor that inhibits TNF-α induced necroptosis. Necroptosis-IN-3 (Compound STX1638) also inhibits 11β-HSD1.		Necroptosis
T11742	K-7174		IL Receptor , TNF
	K-7174 is a novel cell adhesion inhibitor; inhibits the expression of vascular cell adhesion molecule-1 (VCAM-1) induced by either IL-1β or TNF-α.		IL Receptor , TNF
T5101	BW-A 78U	BW-A78U	PDE
	BW-A 78U is a PDE4 inhibitor (IC50: 3 μM). It is not inhibition on the lipopolysaccharide (LPS)-induced TNF-α release.		PDE
T9921	Infliximab		TNF
	Infliximab is a humanized antibody against tumor necrosis factor α TNF-α) that is used in the treatment of Crohn's disease and rheumatoid arthritis.		TNF
T1847	Necrostatin-1	Nec-1,Necrostatin 1	Indoleamine 2,3-Dioxygenase (IDO) , Ferroptosis , Autophagy , RIP kinase
	Necrostatin-1 (Nec-1) is a necrotic apoptosis inhibitor and RIP1 inhibitor with specificity. Necrostatin-1 inhibits TNF-α-induced necrotic apoptosis. Necrostatin-1 also inhibits IDO.
T22021	ACHP	IKK-2 Inhibitor VIII	IκB/IKK
	ACHP (IKK-2 Inhibitor VIII) is a novel selective and potent IKK inhibitor with inhibitory effects on IKK-α and IKK-β. ACHP has anti-HIV-1 activity and inhibits HIV-1 long terminal repeat (LTR)-driven gene expression thro...		IκB/IKK
T9645	CU-115	N-(4-(3,5-bis(trifluoromethyl)phenoxy)phenyl)-2-fluoro-6-iodobenzamide	TLR
	CU-115 is a selective and potent TLR8 antagonist with IC50 of 1.04 µM and =>50 µM for TLR8 and TLR7, respectively. CU-115 decreases production of TNF-α and IL-1β activated by R-848 in THP-1 cells.		TLR
TP1615L	IKKγ NBD Inhibitory Peptide acetate	IKKγ NBD Inhibitory Peptide acetate(372146-18-4 free base)	NF-κB
	IKKγ NBD Inhibitory Peptide acetate is a NEMO-binding domain peptide (NBD peptide) acetate corresponding to the NEMO amino-terminal alpha-helical region. IKKγ NBD Inhibitory Peptide acetate is shown to block TNF-alpha-in...		NF-κB
T3561	CPI1189	CPI-1189,REN-1189,CPI 1189	TNF
	CPI1189 (REN-1189) is a TNF-a release inhibitor potentially for the treatment of sciatica and postherpetic neuralgia.		TNF
T22168	Vialinin A	Terrestrin A	DUB
	Vialinin A (Terrestrin A), a p-terphenyl compound, exhibits antioxidant properties and acts as a potent inhibitor of TNF-α, USP4, USP5, and sentrin/SUMO-specific protease 1 (SENP1). Its efficacy in autoimmune diseases an...		DUB
T4412	Roquinimex	Linomide,LS2616,FCF89,ABR212616	TNF
	Roquinimex (FCF89) (Linomide) is a quinoline derivative immunostimulant which increases NK cell activity and macrophage cytotoxicity; inhibits angiogenesis and reduces the secretion of TNF alpha.		TNF
T4319	Hispidol	(Z)-Hispidol	TNF
	Hispidol ((Z)-Hispidol) ((Z)-Hispidol) is a potential therapeutic for inflammatory bowel disease; inhibits TNF-α induced adhesion of monocytes to colon epithelial cells with an IC50 of 0.50 μM.		TNF
T22698	TLR3-IN-1	CU CPT 4a	TLR
	TLR3-IN-1 (CU CPT 4a) is a selective TLR3 inhibitor (IC50: 3.44 μM in RAW 264.7 cells). It can inhibit TLR3/dsRNA complex-mediated downstream signaling pathways and inhibit the production of TNF-α and IL-1β in whole cell...		TLR
T37558	Necrostatin-5	Nec-5	RIP kinase , Necroptosis
	Necrostatin-5 (Nec-5) is a selective inhibitor of RIP1 kinase and a cell necrosis inhibitor that prevents the death of Fadd-deficient Jurkat cells treated with TNF-α with an EC50 value of 240 nM.		RIP kinase , Necroptosis
T64359	Anti-inflammatory agent 36		Immunology/Inflammation related
	Anti-inflammatory agent 36 is an anti-inflammatory agent. It exhibited dose-dependent inhibition of LPS-induced release of TNF-a and IL-6 in active RAW 264.7 mouse macrophages, IC50=3.69uM and 3.68uM, respectively.		Immunology/Inflammation related
T4062	CAY10602		Sirtuin
	CAY10602 is a SIRT1 activator. CAY10602 was derived from high throughput screening for compounds that increase SIRT1-mediated deacetylation of a SIRT1-specific substrate. Functional assays show that CAY10602 dose-depende...		Sirtuin
T61111	UCB-5307		TNF
	UCB-5307 is a small molecule compound that inhibits TNFR1 signal transduction and downstream function in vitro. The KD of human TNFα is 9 nM. The TNF was directly bound by slow binding kinetics,KD= 6 nM. UCB-5307 can pas...		TNF
T10866	Cot inhibitor-2		TNF , MAPK
	Cot inhibitor-2 is a cot (Tpl2/MAP3K8) inhibitor (IC50: 1.6 nM) with potency, selectivity and oral activity. cot inhibitor-2 inhibits LPS-stimulated TNF-α production in human whole blood with an IC50 of 0.3 μM.		TNF , MAPK
T77484	Atibuclimab		TNF
	Atibuclimab is a chimeric monoclonal antibody targeting CD14, consisting of a mouse variable region and a human IgG4 Fc region. Atibuclimab can be used to treat amyotrophic lateral sclerosis. Atibuclimab reduces LPS-indu...		TNF
T12781	RV01		Others
	RV01 is a novel quinoline-substituted analogue of resveratrol that inhibits DNA damage, reduces ethanol-induced acetaldehyde dehydrogenase (ALDH2) mRNA expression, and has hydroxyl radical scavenging activity. rV01 reduc...		Others
T60657	(R)-STU104		TNF , MAPK
	(R)-STU104 is a novel TAK1-MKK3 protein-protein interaction (PPI) inhibitor that inhibits TNF-α and suppresses the TAK1/MKK3/p38/MnK1/MK2/elF4E signalling pathway by binding to MKK3 and disrupting TAK1 phosphorylation of...		TNF , MAPK
T24816	SP-100030	SP100030,SP 100030	NF-κB
	SP-100030 is a dual inhibitor of NF-κB and activator protein-1 (AP-1), demonstrating potent inhibition with IC50 values of 50 nM for both. It effectively reduces the production of IL-2, IL-8, and TNF-alpha in Jurkat and ...		NF-κB
T67924	ABzOH
	ABzOH is a benzoic acid derivative, similar in structure to non-steroidal anti-inflammatory drugs such as aspirin, with anti-inflammatory, anti-tumor and anti-proliferative effects. ABzOH can not only inhibit the express...
T8477	IQ-3		JNK
	IQ3 is a selective inhibitor of JNK3(JNK3, JNK1 and JNK2 with Kd of 66 nM, 240 nM and 290 nM, respectively). IQ 3 inhibits NF-κB/AP1 transcriptional activity in THP1-Blue cells with IC50 of 1.4 μM, also inhibits TNF-α an...		JNK
T12997	SR-318		p38 MAPK , TNF
	SR-318 is a potent and highly selective inhibitor of p38 MAPK(IC50s of 5 nM, 32 nM and 6.11 μM for p38α, p38β and p38α/β, respectively), has anti-cancer and anti-inflammatory activity.		p38 MAPK , TNF

Compounds

Synonym: TNF-α Antagonist III

Target: TNF

TNF-α (31-45), human acetate

T19584L

Synonym: TNF-α (31-45), human acetate(144796-71-4 free base)

TNF-α (46-65), human

Synonym: AK-Con,Naphcon-a,Clear Eyes,All Clear

Target: Adrenergic Receptor

TNF-α (31-45), human

TNF-α (10-36), human

TP1537

Synonym:

Target:

TNF-α (10-36), human (TFA) (144796-70-3 free base)

TP1479

Synonym: TNF-α (10-36), human (TFA)

Target:

TNF-α (31-45), human TFA (144796-71-4 free base)

TP1636

Synonym: TNF-α (31-45), human TFA

Target:

TNF-α (46-65), human TFA (144796-72-5 free base)

TP1669

Synonym: TNF-α (46-65), human TFA

Target:

SPD304 dihydrochloride

Target: Others, TNF

Synonym: DPC333,DPC 333,DPC-333,BMS561392,BMS 561392

Target: Antioxidant, TNF, COX

Ataquimas

T9840

Synonym:

Target: Immunology/Inflammation related

Synonym: 3-Isoxazolecarboxamide, N-(2,4-dichlorophenyl)-5-methyl-,GBL-5g

1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(7-(1-methyl-1H-pyrazol-4-yl)-2,3,4,9-tetrahydro-1H-carbazol-3-yl)urea

Synonym: Cyclohexanecarboxamide, N-(2-thienylmethyl)-

Target: IL Receptor, TNF

Synonym: Nec-1,Necrostatin 1

Target: Indoleamine 2,3-Dioxygenase (IDO), Ferroptosis, Autophagy, RIP kinase

ACHP

T22021

Synonym: IKK-2 Inhibitor VIII

Target: IκB/IKK

CU-115

T9645

Synonym: N-(4-(3,5-bis(trifluoromethyl)phenoxy)phenyl)-2-fluoro-6-iodobenzamide

Target: TLR

IKKγ NBD Inhibitory Peptide acetate

TP1615L

Synonym: IKKγ NBD Inhibitory Peptide acetate(372146-18-4 free base)

Target: NF-κB

CPI1189

T3561

Synonym: CPI-1189,REN-1189,CPI 1189

Target: TNF

Vialinin A

T22168

Synonym: Terrestrin A

Target: DUB

Roquinimex

T4412

Synonym: Linomide,LS2616,FCF89,ABR212616

Target: TNF

Hispidol

T4319

Synonym: (Z)-Hispidol

Target: RIP kinase, Necroptosis

Anti-inflammatory agent 36

T64359

Synonym:

Target: Immunology/Inflammation related

Synonym: SP100030,SP 100030

Target: p38 MAPK, TNF

Cat No.	Product Name	Synonyms	Targets
T6S1597	Mulberroside A		TNF , Tyrosinase , Interleukin
	1. Mulberroside has nephroprotective, hypoglycemic, and antidiabetic effects. 2. Mulberroside A is a glycosylated stilbene of oxyresveratrol; thus, the deglycosylation of Mulberroside A resulted in enhanced inhibition of...		TNF , Tyrosinase , Interleukin
T2932	Ginsenoside Rh1	Sanchinoside B2,Prosapogenin A2,20(S)-Ginsenoside Rh1,Sanchinoside Rh1	IL Receptor , TNF , Endogenous Metabolite , PPAR , Interleukin
	Ginsenoside Rh1 (Sanchinoside B2) , one of the main constituents of Panax ginseng, exhibits anti-inflammatory effect.
TC0036	Compound Lup-20(29)-en-3-yl acetate		IL Receptor , VEGFR , Others , TNF , COX
	Lupeol acetate, a derivative of Lupeol, inhibits the progression of rheumatoid arthritis by downregulating TNF-α, IL-1β, MCP-1, COX-2, VEGF and granzyme B.		IL Receptor , VEGFR , Others , TNF , COX
T8288	14-Deoxyandrographolide		Apoptosis , Others
	14-Deoxyandrographolide is a bioactive compound of Andrographis paniculata with hepatoprotective efficacy. It desensitizes hepatocytes to TNF-α-mediated apoptosis through the release of TNFRSF1A release.		Apoptosis , Others
TN2539	1beta-Hydroxyalantolactone		IL Receptor , TNF
	1beta-Hydroxyalantolactone is a small molecular compound isolated from the flower head of the medicinal plant giant British flower, which can inhibit the expression of TNF-α, IL-17 and IFN-γ in cells, promote the secreti...		IL Receptor , TNF
T0131	Cepharanthine	NSC-623442	Apoptosis , TNF , HIV Protease , Autophagy
	Cepharanthine (NSC-623442), a biscoclaurine alkaloid, suppresses tumor necrosis factor (TNF)-α-mediated NFκB stimulation, plasma membrane lipid peroxidation and platelet aggregation and inhibits cytokine production.		Apoptosis , TNF , HIV Protease , Autophagy
T2720	Ginsenoside Rc	Panaxoside Rc	Others , TNF , GABA Receptor , Interleukin
	Ginsenoside Rc (Panaxoside Rc) is one of the ginsenosides from Panax ginseng, inhibits the expression of TNF-α and IL-1β.		Others , TNF , GABA Receptor , Interleukin
TN7235	4-methoxylonchocarpin		TNF , NF-κB
	4-methoxylonchocarpin was isolated from the roots of Abrus precatorius as a potent anti-inflammatory compound. 4-methoxylonchocarpin inhibited NF-κB-activated TNF expression by inhibiting the binding of LPS to TLR4 in ma...		TNF , NF-κB
TN1511	Cleomiscosin A		LDL , Antioxidant , TNF
	Cleomiscosin A is derived from Acer okamotoanum leaf and twig and shows inhibitory activity to TNF-α secretion of the mouse peritoneal macrophages. Cleomiscosin A can be used in studies about the prevention of LDL oxidat...		LDL , Antioxidant , TNF
T3000	Magnolol	NSC 293099,5,5'-Diallyl-2,2'-biphenyldiol	NF-κB , Retinoid Receptor , Antibacterial , PPAR , p53 , Autophagy
	Magnolol (5,5'-Diallyl-2,2'-biphenyldiol) is a dual agonist of RXRα( EC50=10.4 μM) and PPARγ(EC50=17.7 μM). It blocks TNF-α-induced NF-KB activation.
T5754	Kavain		NF-κB , GABA Receptor
	Kavain, a compound extracted from the Kava plant, Piper methysticum, is found to be involved in TNF-α expression in human and mouse cells via regulation of transcriptional factors such as NF-kB and LITAF.		NF-κB , GABA Receptor
T3927	Phellopterin		GABA Receptor
	Phellopterin is a partial agonist of the central benzodiazepine receptors in vitro. Phellopterin shows a cytotoxic effect on RAW264.7 cell at the concentration from 40 to 400 μM. Phellopterin reduce TNF-alpha-induced VCA...		GABA Receptor
TN6967	(R)-Isomucronulatol	(-)-Isomucronulatol,2H-1-Benzopyran-7-ol	Apoptosis
	(R)-Isomucronulatol (2H-1-Benzopyran-7-ol), a flavonoid that can be extracted from the leaves of Astragalus membranaceus, Sophora japonica, Sclerotium tigrinum, and Glycyrrhiza glabra, inhibits the proliferation and apop...		Apoptosis
T4973	Paraxanthine	1,7-DIMETHYLXANTHINE	Endogenous Metabolite
	Paraxanthine (1,7-dimethylxanthine) is a metabolite of caffeine (sc-202514) which functions as an adenosine receptor ligand and a PARP-1 inhibitor in pulmonary epithelial cells. Studies suggest that Paraxanthine is struc...		Endogenous Metabolite
T2768	Saikosaponin A		NF-κB , Antibacterial , Liver X Receptor
	Saikosaponin A has a variety of pharmacological benefits, including antiepileptic, anti-osteoporosis, antioxidant, anti-in ammatory, immunomodulatory, and anti-bacterial activities. It can effectively attenuate neuropath...		NF-κB , Antibacterial , Liver X Receptor
T6S1256	Ruscogenin		NOS , NF-κB , NOD-like Receptor (NLR)
	1. Ruscogenin has anti-inflammatory activity, suppressed zymosan A-evoked peritoneal total leukocyte migration in mice in a dose-dependent manner, 2. Ruscogenin inhibited adhesion of leukocytes to a human umbilical vein ...		NOS , NF-κB , NOD-like Receptor (NLR)
T4904	1-Methylguanidine hydrochloride		Others , Endogenous Metabolite
	Methylguanidine (MG) is a guanidine compound deriving from protein catabolism. It is also a product of putrefaction. Methylguanidine is a suspected uraemic toxin that accumulates in renal failure, however it also exhibit...		Others , Endogenous Metabolite
T4S2063	Tetrahydrocoptisine	STYLOPINE	ERK , p38 MAPK , NF-κB
	1. Tetrahydrocoptisine (STYLOPINE) has effective effects in suppressing inflammation. 2. Tetrahydrocoptisine possesses a protective effect on LPS-induced ALI through inhibiting of NF-κB signaling pathways, which may invo...		ERK , p38 MAPK , NF-κB
T6S1495	Ginsenoside Rk3		Others , NF-κB
	1. Ginsenoside Rk3 and Rh4 could have a role in treating inflammatory diseases. 2. Ginsenoside Rk3 is often used as a major ingredient of the compound preparation for ischemic heart diseases.		Others , NF-κB
T6S0653	Linarin	Buddleoflavonoloside,Buddleoside,Acacetin-7-O-rutinoside,Acaciin,Linarine	TNF , AChE
	1. Linarin (Acacetin-7-O-rutinoside) (acacetin-7-O-β-d-rutinoside) shows selective dose dependent inhibitory effect on acetylcholinesterase. 2. Linarin alleviates GalN/LPS-induced liver injury by suppressing TNF-α-mediat...		TNF , AChE
T3240	Citronellol	dihydrogeraniol,(±)-β-Citronellol	Reactive Oxygen Species
	Citronellol ((±)-β-Citronellol) is used in insect repellents and perfumes and as a mite attractant.		Reactive Oxygen Species
T6S0139	Neobavaisoflavone		Apoptosis , DNA/RNA Synthesis
	1. Neobavaisoflavone is isolated as a DNA polymerase inhibitor. 2. Neobavaisoflavone might be a potential anabolic agent to treat bone loss-associated diseases. 3. Neobavaisoflavone has anti-inflammatory activity, can si...		Apoptosis , DNA/RNA Synthesis
T2823	Crocin	Gardenia Yellow,Alpha-Crocin	Others
	Crocin (Gardenia Yellow) is a water-soluble carotenoid pigment of saffron (Crocus sativus L. ) that has been used as a spice for flavoring and coloring food preparations, and in Chinese traditional medicine as an anodyne...		Others
T6S1049	Wilforine		ATPase
	Wilforine is a sesquiterpene pyridine alkaloid; important bioactive compound in T. wilfordii plants, and is effective in treating idiopathic pulmonary fibrosis. Wilforine has anti-inflammatory effect, which might be medi...		ATPase
T2S0843	Negletein	7-O-Methylbaicalein,Baicalein-7-methylether	IL Receptor , TNF , NOS , Interleukin
	1. Negletein (7-O-Methylbaicalein) has anti-inflammatory and immunomodulatory activities via inhibition of TNF-α, iNOS and IL-1β. 2. Negletein as a neuroprotectant enhances the action of nerve growth factor and induces n...		IL Receptor , TNF , NOS , Interleukin
T5S0045	Isofraxidin	6,8-Dimethoxyumbelliferone,Phytodolor	MMP , ERK , p38 MAPK , TLR , COX
	1. Isofraxidin (Phytodolor) protects leukemia cells from radiation-induced apoptosis via ROS/mitochondria pathway in a p53-independent manner. 2. Isofraxidin has a protective effect against LPS-induced ALI, and the prote...		MMP , ERK , p38 MAPK , TLR , COX
T6S1487	Ginsenoside Rg5		NF-κB , COX , IGF-1R
	1. Ginsenoside Rg5 could be a beneficial agent for the treatment of Alzheimer's disease. 2. Ginsenoside Rg5 suppresses LPS-induced nitric oxide (NO) production and proinflammatory TNF-α secretion. 3. Ginsenoside Rg5 can ...		NF-κB , COX , IGF-1R
T6S1917	Schisandrol B	Gomisin A,TJN-101,Besigomsin,Gamma-Schisandrin,Schizandrol B,Wuweizi alcohol-B	P450 , Reactive Oxygen Species , Autophagy
	1. Schisandrol B (Besigomsin) may exert neuroprotective effects by attenuating the microglia-mediated neuroinflammatory response via inhibiting the TLR4-mediated NF-κB and MAPKs signaling pathways. 2. Schisandrol B has a...		P450 , Reactive Oxygen Species , Autophagy
T4S1521	1,4-Dicaffeoylquinic acid		HIV Protease
	1,4-Dicaffeoylquinic acid has antioxidant activity.1,4-Dicaffeoylquinic acid is a potent and highly selective class of HIV-1 integrase inhibitors, inhibitsHIV-1 replication in MT-2 cell culture at non-toxic concentration...		HIV Protease
T2S2264	Linalool	Linalol,(±)-Linalool,Phantol	Apoptosis , IL Receptor , TNF , Endogenous Metabolite , iGluR
	1. Linalool (Linalol), a natural compound of the essential oils, has been shown to have antinociceptive, antimicrobial, and anti-inflammatory properties. 2. Linalool was protected against LPS/GalN-induced liver injury th...
T3893	Forsythoside B		TNF , NF-κB
	Forsythoside B binds to LPS and reduces the biological activity of serum LPS, and inhibits NF-κB activation. Forsythoside B inhibits the inflammatory response and has antioxidant properties. Potent neuroprotective effect...		TNF , NF-κB
T6S1572	Sauchinone		ERK , p38 MAPK , NF-κB
	1. Sauchinone is a useful adjunctive treatment for bacterial infection. 2. Sauchinone, an active lignan found in Saururus chinensis, to regulate the activation of HSCs, to prevent liver fibrosis, and to inhibit oxidative...		ERK , p38 MAPK , NF-κB
T3673	Mollugin	Rubimaillin	HER , JAK
	Mollugin (Rubimaillin) may be a JAK2 inhibitor and inhibits LPS-induced inflammatory responses by blocking the activation of the JAK-STAT pathway. Mollugin as a candidate for a chemotherapeutic agent in OSCCs via the upr...		HER , JAK
T60598	Thunbergol
	Thunbergol (Isocembrol) (Compound 17) is a potent inhibitor of TNF-α (IC 50 = 7.2 μM) [1].
TMA0627	Taxiresinol		TNF
	Taxiresinol shows anticancer, antinociceptive, and antiallergic activities, it shows inhibitory activity on induced histamine release from the human basophilic cell line, KU812. Taxiresinol can protect the hepatocytes fr...		TNF
T13625	Coronalolic acid	Coronalonic acid	NF-κB
	Coronalolic acid is a natural product extracted from the Gardenia sootepenesis Hutch. It inhibits TNF-α-induced NF-κB activity and NO production.		NF-κB
T26545	Acanthoic acid	NP1302,NP 1302: NP-1302
	Acanthoic acid is a pimaradiene diterpene isolated from Acanthopanax koreanum with anti-inflammatory activities. Acanthoic acid downregulates LPS-induced IL-1β, IL-6 and TNF-α production in BALF, attenuates lung histopat...
T38635	Kdo2-Lipid A ammonium		TNF , TLR , Prostaglandin Receptor
	Kdo2-Lipid A ammonium (KLA) is a selective and potent TLR4 agonist, a lipopolysaccharide.Kdo2-Lipid A ammonium induces the release of TNF and PGE2.		TNF , TLR , Prostaglandin Receptor
TN2102	Procurcumenol		Others , TNF
	Procurcumenol is an inhibitor of Nitric Oxide. Procurcumenol and epicurcumenol have inhibitory effects on release of tumor necrosis factor-a (TNF-a).		Others , TNF
T12975	Sootepin D		NF-κB
	Sootepin D is a triterpene from the apical bud of Gardenia sootepensis, and is TNF-α-induced NF-κB inhibitor(IC50 of 8.3μM),with anti-inflammatory activity.		NF-κB
TN2224	Soyasapogenol A		TNF
	Soyasapogenol A shows estrogenic and hepatoprotective activities, it directly prevents apoptosis of hepatocytes, and secondly, inhibits the elevation of plasma TNF-α±, which consequently resulted in the prevention of liv...		TNF
TN4679	Nudiposide		IL Receptor , TNF
	Nudiposide has significant neuroprotective activities against glutamate-injured neurotoxicity in HT22 cells. It also exhibits protective effect against sepsis in a mouse model and can decrease the plasma levels of TNF-α,...		IL Receptor , TNF
TN5351	Cycloshizukaol A
	Cycloshizukaol A prevents monocyte adhesion to HUVEC through the inhibition of cell adhesion molecules expression stimulated by TNF-alpha, it inhibits PMA-induced homotypic aggregation of HL-60 cells without cytotoxicity...
TN1228	25S-Inokosterone		TNF
	25S-Inokosterone exhibits potent inhibition against TNF-expression levels in A23187 plus phorbol-myrisrate acetate-induced RBL-2H3 cells. 25S-Inokosterone has excellent anti-atopy activity, thus 25S-Inokosterone could be...		TNF
T5768	Bruceine B		TNF , Parasite
	Bruceine B, a potent inhibitor of leukocyte-endothelial cell adhesion, may have anti-inflammatory activity, it can inhibit neutrophil adhesion to lipopolysaccharide-stimulated HUVEC and T cell adhesion to TNF-stimulated ...		TNF , Parasite
T72799	Sinulatumolin E
	Sinulatumolin E (compound 6), a terpenoid, demonstrates notable anti-inflammatory properties by significantly inhibiting TNF-α with an IC 50 value of 3.6 μM.
T38338	Quinolactacin A
	Quinolactactin A is a quinolone fungal metabolite originally isolated from Penicillium. It inhibits TNF production induced by LPS in murine peritoneal macrophages (IC50 = 12.2 μg/ml). It is not active against a variety o...
TN4303	Isokaempferide		ATPase , Potassium Channel , Calcium Channel , TNF , Prostaglandin Receptor
	Isokaempferide shows hepatoprotective, antiproliferative, and anti-inflammatory effects, the anti-inflammatory effects can be explained, at least in part, by reducing neutrophil degranulation, myeloperoxidase activity, m...
TN2461	Loganic acid 6′-O-β-D-glucoside	8-Epi-Loganic acid-6'-O-β-D-glucoside	Others
	Loganic acid 6′-O-β-D-glucoside (8-Epi-Loganic acid-6'-O-β-D-glucoside) is a natural product from Cistanche deserticola and inhibts the production of LPS-induced NO and TNF-α.		Others
TN6539	Pd-C-II
	Pd-C-II has anti-inflammation activity, it can inhibit TNF-α production and iNOS protein expression and inhibit COX-2 protein expression in LPS-stimulated RAW 264.7 cells. Pd-C-II inhibits anaphylactic mediator release f...
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Natural Products

Mulberroside A

T6S1597

Synonym:

Target: TNF, Tyrosinase, Interleukin

Ginsenoside Rh1

T2932

Synonym: Sanchinoside B2,Prosapogenin A2,20(S)-Ginsenoside Rh1,Sanchinoside Rh1

Target: IL Receptor, TNF, Endogenous Metabolite, PPAR, Interleukin

Compound Lup-20(29)-en-3-yl acetate

TC0036

Synonym:

Target: IL Receptor, VEGFR, Others, TNF, COX

14-Deoxyandrographolide

T8288

Synonym:

Target: Apoptosis, Others

1beta-Hydroxyalantolactone

TN2539

Synonym:

Target: IL Receptor, TNF

Cepharanthine

T0131

Synonym: NSC-623442

Target: Apoptosis, TNF, HIV Protease, Autophagy

Ginsenoside Rc

T2720

Synonym: Panaxoside Rc

Target: Others, TNF, GABA Receptor, Interleukin

4-methoxylonchocarpin

Target: LDL, Antioxidant, TNF

Magnolol

T3000

Synonym: NSC 293099,5,5'-Diallyl-2,2'-biphenyldiol

Target: NF-κB, Retinoid Receptor, Antibacterial, PPAR, p53, Autophagy

Kavain

T5754

Synonym:

Target: NF-κB, GABA Receptor

Phellopterin

T3927

Synonym:

Target: GABA Receptor

(R)-Isomucronulatol

TN6967

Synonym: (-)-Isomucronulatol,2H-1-Benzopyran-7-ol

Target: Apoptosis

Paraxanthine

T4973

Synonym: 1,7-DIMETHYLXANTHINE

Target: Endogenous Metabolite

Saikosaponin A

T2768

Synonym:

Target: NF-κB, Antibacterial, Liver X Receptor

Ruscogenin

T6S1256

Synonym:

Target: NOS, NF-κB, NOD-like Receptor (NLR)

1-Methylguanidine hydrochloride

T4904

Synonym:

Target: Others, Endogenous Metabolite

Tetrahydrocoptisine

T4S2063

Synonym: STYLOPINE

Target: ERK, p38 MAPK, NF-κB

Ginsenoside Rk3

T6S1495

Synonym:

Target: Others, NF-κB

Linarin

T6S0653

Synonym: Buddleoflavonoloside,Buddleoside,Acacetin-7-O-rutinoside,Acaciin,Linarine

Target: TNF, AChE

Citronellol

T3240

Synonym: dihydrogeraniol,(±)-β-Citronellol

Target: Reactive Oxygen Species

Neobavaisoflavone

T6S0139

Synonym:

Target: Apoptosis, DNA/RNA Synthesis

Crocin

T2823

Synonym: Gardenia Yellow,Alpha-Crocin

Synonym: 7-O-Methylbaicalein,Baicalein-7-methylether

Target: IL Receptor, TNF, NOS, Interleukin

Isofraxidin

T5S0045

Synonym: 6,8-Dimethoxyumbelliferone,Phytodolor

Target: MMP, ERK, p38 MAPK, TLR, COX

Ginsenoside Rg5

T6S1487

Synonym:

Target: NF-κB, COX, IGF-1R

Schisandrol B

T6S1917

Synonym: Gomisin A,TJN-101,Besigomsin,Gamma-Schisandrin,Schizandrol B,Wuweizi alcohol-B

Target: P450, Reactive Oxygen Species, Autophagy

1,4-Dicaffeoylquinic acid

Synonym: Linalol,(±)-Linalool,Phantol

Target: Apoptosis, IL Receptor, TNF, Endogenous Metabolite, iGluR

Target: ERK, p38 MAPK, NF-κB

Synonym: Coronalonic acid

Target: NF-κB

Acanthoic acid

T26545

Synonym: NP1302,NP 1302: NP-1302

Target:

Kdo2-Lipid A ammonium

T38635

Synonym:

Target: TNF, TLR, Prostaglandin Receptor

Procurcumenol

TN2102

Synonym:

Target: Others, TNF

Target: IL Receptor, TNF

Target: TNF, Parasite

Target: ATPase, Potassium Channel, Calcium Channel, TNF, Prostaglandin Receptor

Loganic acid 6′-O-β-D-glucoside

TN2461

Synonym: 8-Epi-Loganic acid-6'-O-β-D-glucoside

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Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-01294	TNF alpha Protein, Mouse, Recombinant	Mouse	E. coli
	TNF alpha Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.39 kDa and the accession number is P06804.
TMPJ-00779	TNF alpha Protein, Rabbit, Recombinant	Rabbit	E. coli
	Tumor necrosis factor alpha (TNFα) is the prototypic ligand of the TNF superfamily. TNFα forms a homotrimer and functions by activating two types of receptors TNF-R1 (TNF receptor type 1,p55R) and TNF-R2 (TNF receptor ty...
TMPJ-00137	APRIL/TNFSF13 Protein, Human, Recombinant (Flag & His)	Human	HEK293 Cells
	APRIL (a proliferation-inducing ligand), also known as TNFSF13, TALL2, TRDL1, and CD256, is a member of the TNF ligand superfamily. It is synthesized as a 32 kDa proprotein which is cleaved by furin in the Golgi to relea...
TMPY-05187	TNF alpha Protein, Mouse, Recombinant, Biotinylated	Mouse	E. coli
	TNF alpha Protein, Mouse, Recombinant, Biotinylated is expressed in E. coli expression system. The predicted molecular weight is 17.4 kDa and the accession number is P06804.
TMPJ-00125	TNF alpha Protein, Human, Recombinant (aa 57-233, His)	Human	E. coli
	TNF alpha Protein, Human, Recombinant (aa 57-233, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 18 KDa and the accession number is P01375.
TMPJ-00124	TNF alpha Protein, Human, Recombinant (aa 77-233, His)	Human	E. coli
	TNF alpha Protein, Human, Recombinant (aa 77-233, His) is expressed in E. coli expression system with C-6xHis tag. The predicted molecular weight is 16 KDa and the accession number is P01375.
TMPJ-00288	TNF RII Protein, Human, Recombinant (mFc)	Human	HEK293 Cells
	TNF RII Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 60 KDa and the accession number is P20333.
TMPJ-00287	TNF RII Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	TNF RII Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 60-90 KDa and the accession number is P20333.
TMPJ-00546	EFNA1 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Ephrin-A1 is a member of the A-type ephrin family of cell surface proteins that function as ligands for the A-type Eph receptor tyrosine kinase family. Ephrin-A1 can be induced by TNF and IL1B. Its expression levels can ...
TMPY-02153	TNF beta Protein, Human, Recombinant	Human	E. coli
	Lymphotoxin-alpha, also known as LT-alpha, TNF-beta, Tumor necrosis factor ligand superfamily member 1, LTA TNFSF1, and TNFB, is a secreted protein that belongs to the tumor necrosis factor family. TNF-beta/TNFSF1/Lympho...
TMPK-00176	BAFF/TNFSF13B Trimer Protein, Human, Recombinant (His & Flag)	Human	HEK293 Cells
	B-cell activating factor (BAFF) also known as tumor necrosis factor ligand superfamily member 13B is a protein that in humans is encoded by the TNFSF13B gene.BAFF is a cytokine that belongs to the tumor necrosis factor (...
TMPJ-00662	RANKL/TNFSF11/CD254 Protein, Human, Recombinant (E. coli)	Human	E. coli
	CD254, also known as RANKL, TNFSF11, TRANCE, OPGL and ODF, is a type II membrane protein of the tumor necrosis factor (TNF) superfamily, and affects the immune system and control bone regeneration and remodeling. RANKL i...
TMPJ-01172	IL-17 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. Mature mouse IL-17A shares 61% and 89% amino acid seque...
TMPJ-00994	LTBR Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	It is a single-pass type I membrane protein and contains 4 TNFR-Cys repeats. The protein is a member of the tumor necrosis factor (TNF) family of receptors. It is expressed on the surface of most cell types, including ce...
TMPY-06981	IL-1 alpha/IL-1A Protein, Human, Recombinant (E. coli)	Human	E. coli
	IL-1 alpha is a member of the interleukin 1 cytokine family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proli...
TMPJ-01312	TWEAKR/TNFRSF12A Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Tumor necrosis factor receptor superfamily member 12A(Tnfrsf12a) is a single-pass type I membrane protein and contains 1 TNFR-Cys repeat. It is weak inducer of apoptosis in some cell types.It promotes angiogenesis and it...
TMPK-01382	TNFR2/CD120b/TNFR1B Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	Tumor Necrosis Factor Receptor II (TNF RII), also known as TNFRSF1B, p75/p80, and CD120b, is a type I transmembrane protein that belongs to the TNF receptor superfamily. It has a molecular weight of approximately 75 kDa....
TMPK-01254	BAFFR/TNFRSF13C Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	BAFF binds to three TNF receptor superfamily members: B-cell maturation antigen (BCMA / TNFRSF17), transmembrane activator and calcium-modulator and cyclophilin ligand interactor (TACI/TNFRSF13B) and BAFF receptor (BAFF ...
TMPK-01163	APRIL/TNFSF13 Protein, Mouse, Recombinant (His & Flag)	Mouse	HEK293 Cells
	The APRIL (a proliferation-inducing ligand), also known as TNFSF13, TALL2, TRDL1, and CD256, is a member of the TNF ligand superfamily.Both APRIL and its close relative BAFF bind and signal through the TNF superfamily re...
TMPK-00070	BAFFR/TNFRSF13C Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	BAFF binds to three TNF receptor superfamily members: B-cell maturation antigen (BCMA/TNFRSF17), transmembrane activator and calcium-modulator and cyclophilin ligand interactor (TACI/TNFRSF13B) and BAFF receptor (BAFF R/...
TMPK-00141	APRIL/TNFSF13 Trimer Protein, Human, Recombinant (His & Flag)	Human	HEK293 Cells
	The APRIL (a proliferation-inducing ligand), also known as TNFSF13, TALL2, TRDL1, and CD256, is a member of the TNF ligand superfamily.Both APRIL and its close relative BAFF bind and signal through the TNF superfamily re...
TMPK-00171	TRAIL Trimer Protein, Human, Recombinant (His & Flag)	Human	HEK293 Cells
	Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is a member of the TNF superfamily that can initiate the apoptosis pathway by binding to its associated death receptors DR4 and DR5. The activation of...
TMPK-01349	APRIL/TNFSF13 Trimer Protein, Cynomolgus, Recombinant (His & Avi, Flag)	Cynomolgus	HEK293 Cells
	The APRIL (a proliferation-inducing ligand), also known as TNFSF13, TALL2, TRDL1, and CD256, is a member of the TNF ligand superfamily.Both APRIL and its close relative BAFF bind and signal through the TNF superfamily re...
TMPK-00140	APRIL/TNFSF13 Trimer Protein, Human, Recombinant (His & Avi & Flag), Biotinylated	Human	HEK293 Cells
	The APRIL (a proliferation-inducing ligand), also known as TNFSF13, TALL2, TRDL1, and CD256, is a member of the TNF ligand superfamily.Both APRIL and its close relative BAFF bind and signal through the TNF superfamily re...
TMPH-02876	RIPK1 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Serine-threonine kinase which is a key regulator of TNF-mediated apoptosis, necroptosis and inflammatory pathways. Exhibits kinase activity-dependent functions that regulate cell death and kinase-independent scaffold fun...
TMPK-00631	DR3/TNFRSF25 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	TNF-like ligand 1 A (TL1A) and death receptor 3 (DR3) are a ligand-receptor pair involved in the pathogenesis of inflammatory bowel disease. Group 3 innate lymphoid cells (ILC3s) regulate intestinal immunity and highly e...
TMPK-00564	TNFR1/CD120a/TNFRSF1A Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	Tumour necrosis factor alpha (TNF-α) is a pleiotropic cytokine with both injurious and protective functions, which are thought to diverge at the level of its two cell surface receptors, TNFR1 and TNFR2. In the setting of...
TMPK-00142	APRIL/TNFSF13 Trimer Protein (Primary Amine Labeling), Human, Recombinant (His & Flag), Biotinylated	Human	HEK293 Cells
	The APRIL (a proliferation-inducing ligand), also known as TNFSF13, TALL2, TRDL1, and CD256, is a member of the TNF ligand superfamily.Both APRIL and its close relative BAFF bind and signal through the TNF superfamily re...
TMPJ-01107	PAP Protein, Human, Recombinant (His)	Human	E. coli
	Human PAP, also known as 28 kDa heat- and acid-stable phosphoprotein, PDGF-associated protein, PDGFA-associated protein 1, PDAP1, HASPP28, is a protein which belongs to the PDAP1 family. The encoded protein in rodents ha...
TMPY-03416	TNFAIP8 Protein, Human, Recombinant (His)	Human	E. coli
	Tumor necrosis factor (TNF)-alpha-induced protein 8 (TNFAIP8) family is a newly identified protein with vital roles in maintaining immune homeostasis. Tumor necrosis factor-alpha-inducible protein 8 (TNFAIP8) is a TNF-al...
TMPH-02195	TXNDC17 Protein, Human, Recombinant (GST)	Human	E. coli
	Disulfide reductase. May participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions. Modulates TNF-alpha signalin...
TMPJ-00272	RELT/TNFRSF19L Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Tumor necrosis factor receptor superfamily member 19L (TNFRSF19L), also known as Receptor expressed in lymphoid tissues and RELT, is a member of the TNF-receptor superfamily. TNFRSF19L is a single-pass type membrane prot...
TMPH-01695	MLKL Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Does not have protein kinase activity. Activated following phosphorylation by RIPK3, leading to homotrimerization, localizat...
TMPK-01203	TNFRSF19 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	A novel susceptibility gene TNFRSF19, which encodes an orphan member of the TNF receptor superfamily known to be associated with nasopharyngeal carcinoma (NPC) and lung cancer risk. TNFRSF19, a susceptibility gene for na...
TMPH-01694	MLKL Protein, Human, Recombinant (E. coli, His)	Human	E. coli
	Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Does not have protein kinase activity. Activated following phosphorylation by RIPK3, leading to homotrimerization, localizat...
TMPK-00276	TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	DR5, also called TRAIL R2, TRICK 2, TNFRSF10B, and MK is a type 1 TNF R superfamily, membrane protein which is a receptor for TRAIL (APO2 ligand). DR5 is a receptor for the cytotoxic ligand TNFSF10/TRAIL. The resulting d...
TMPJ-00168	HVEM Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Mouse Protein Tnfrsf14, is a type I transmembrane protein belonging to the TNF receptor superfamily. It is tumor necrosis factor receptor superfamily member 14 and expressed on the surface of T cells during the resting s...
TMPK-00064	BCMA/TNFRSF17 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)	Cynomolgus,Rhesus	HEK293 Cells
	B-cell maturation antigen (BCMA or BCM), also known as tumor necrosis factor receptor superfamily member 17 (TNFRSF17), is a protein that in humans is encoded by the TNFRSF17 gene.TNFRSF17 is a cell surface receptor of t...
TMPK-00152	CD27/TNFRSF7 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	CD27, also known as TNFRSF7, is an approximately 55 kDa transmembrane protein in the TNF receptor superfamily. It functions as a co‑stimulatory molecule that supports lymphocyte activation and survival. It binds to ligan...
TMPH-02650	FCMR/FAIM3 Protein, Mouse, Recombinant (His & SUMO)	Mouse	E. coli
	May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory...
TMPH-02770	TNF beta Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM. In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and is cytotoxic for a w...
TMPJ-00066	BCMA/TNFRSF17 Protein, Human, Recombinant (His & Flag)	Human	HEK293 Cells
	B cell maturation antigen (BCMA) is a member of the TNF receptor superfamily. It has been designated TNFRSF17. Mouse BCMA is a 185 amino acid (aa) protein consisting of a 49 aa extracellular domain, a 23 aa transmembrane...
TMPK-00489	TL1A/TNFSF15 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)	Cynomolgus,Rhesus	HEK293 Cells
	TNF superfamily member 15 (TNFSF15), a cytokine largely produced by vascular endothelial cells and a specific inhibitor of the proliferation of these same cells, can inhibit VEGF-induced vascular permeability in vitro an...
TMPK-00071	BCMA/TNFRSF17 Protein, Mouse, Recombinant (His & Avi)	Mouse	HEK293 Cells
	B-cell maturation antigen (BCMA or BCM), also known as tumor necrosis factor receptor superfamily member 17 (TNFRSF17), is a protein that in humans is encoded by the TNFRSF17 gene.TNFRSF17 is a cell surface receptor of t...
TMPK-00065	BCMA/TNFRSF17 Trimer Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	B-cell maturation antigen (BCMA or BCM), also known as tumor necrosis factor receptor superfamily member 17 (TNFRSF17), is a protein that in humans is encoded by the TNFRSF17 gene.TNFRSF17 is a cell surface receptor of t...
TMPK-00066	BCMA/TNFRSF17 Protein, Human, Recombinant (His & Avi), FITC-Labeled	Human	HEK293 Cells
	B-cell maturation antigen (BCMA or BCM), also known as tumor necrosis factor receptor superfamily member 17 (TNFRSF17), is a protein that in humans is encoded by the TNFRSF17 gene.TNFRSF17 is a cell surface receptor of t...
TMPK-00068	BCMA/TNFRSF17 Trimer Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	B-cell maturation antigen (BCMA or BCM), also known as tumor necrosis factor receptor superfamily member 17 (TNFRSF17), is a protein that in humans is encoded by the TNFRSF17 gene.TNFRSF17 is a cell surface receptor of t...
TMPK-00072	BCMA/TNFRSF17 Protein, Mouse, Recombinant (His & Avi), Biotinylated	Mouse	HEK293 Cells
	B-cell maturation antigen (BCMA or BCM), also known as tumor necrosis factor receptor superfamily member 17 (TNFRSF17), is a protein that in humans is encoded by the TNFRSF17 gene.TNFRSF17 is a cell surface receptor of t...
TMPK-00130	LIGHT/TNFSF14 Trimer Protein, Human, Recombinant (His & Flag)	Human	HEK293 Cells
	LIGHT, also known as tumor necrosis factor superfamily member 14 (TNFSF14), is a secreted protein of the TNF superfamily. It is recognized by herpesvirus entry mediator (HVEM), as well as decoy receptor 3.This protein ha...
TMPK-00143	TL1A/TNFSF15 Trimer Protein, Human, Recombinant (His & Flag)	Human	HEK293 Cells
	TNF superfamily member 15 (TNFSF15), a cytokine largely produced by vascular endothelial cells and a specific inhibitor of the proliferation of these same cells, can inhibit VEGF-induced vascular permeability in vitro an...
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TNF alpha Protein, Mouse, Recombinant

TMPY-01294

Species: Mouse

Expression System: E. coli

TNF alpha Protein, Rabbit, Recombinant

TMPJ-00779

Species: Rabbit

Expression System: E. coli

APRIL/TNFSF13 Protein, Human, Recombinant (Flag & His)

TMPJ-00137

Species: Human

Expression System: HEK293 Cells

TNF alpha Protein, Mouse, Recombinant, Biotinylated

TMPY-05187

Species: Mouse

Expression System: E. coli

TNF alpha Protein, Human, Recombinant (aa 57-233, His)

TMPJ-00125

Species: Human

Expression System: E. coli

TNF alpha Protein, Human, Recombinant (aa 77-233, His)

TMPJ-00124

Species: Human

Expression System: E. coli

TNF RII Protein, Human, Recombinant (mFc)

TMPJ-00288

Species: Human

Expression System: HEK293 Cells

TNF RII Protein, Human, Recombinant (hFc)

TMPJ-00287

Species: Human

Expression System: HEK293 Cells

EFNA1 Protein, Human, Recombinant (hFc)

TMPJ-00546

Species: Human

Expression System: HEK293 Cells

TNF beta Protein, Human, Recombinant

TMPY-02153

Species: Human

Expression System: E. coli

BAFF/TNFSF13B Trimer Protein, Human, Recombinant (His & Flag)

TMPK-00176

Species: Human

Expression System: HEK293 Cells

RANKL/TNFSF11/CD254 Protein, Human, Recombinant (E. coli)

TMPJ-00662

Species: Human

Expression System: E. coli

IL-17 Protein, Mouse, Recombinant (His)

TMPJ-01172

Species: Mouse

Expression System: HEK293 Cells

LTBR Protein, Mouse, Recombinant (hFc)

TMPJ-00994

Species: Mouse

Expression System: HEK293 Cells

IL-1 alpha/IL-1A Protein, Human, Recombinant (E. coli)

TMPY-06981

Species: Human

Expression System: E. coli

TWEAKR/TNFRSF12A Protein, Mouse, Recombinant (hFc)

TMPJ-01312

Species: Mouse

Expression System: HEK293 Cells

TNFR2/CD120b/TNFR1B Protein, Cynomolgus, Recombinant (His)

TMPK-01382

Species: Cynomolgus

Expression System: HEK293 Cells

BAFFR/TNFRSF13C Protein, Cynomolgus, Recombinant (His)

TMPK-01254

Species: Cynomolgus

Expression System: HEK293 Cells

APRIL/TNFSF13 Protein, Mouse, Recombinant (His & Flag)

TMPK-01163

Species: Mouse

Expression System: HEK293 Cells

BAFFR/TNFRSF13C Protein, Human, Recombinant (His & Avi), Biotinylated

TMPK-00070

Species: Human

Expression System: HEK293 Cells

APRIL/TNFSF13 Trimer Protein, Human, Recombinant (His & Flag)

TMPK-00141

Species: Human

Expression System: HEK293 Cells

TRAIL Trimer Protein, Human, Recombinant (His & Flag)

TMPK-00171

Species: Human

Expression System: HEK293 Cells

APRIL/TNFSF13 Trimer Protein, Cynomolgus, Recombinant (His & Avi, Flag)

TMPK-01349

Species: Cynomolgus

Expression System: HEK293 Cells

APRIL/TNFSF13 Trimer Protein, Human, Recombinant (His & Avi & Flag), Biotinylated

TMPK-00140

Species: Human

Expression System: HEK293 Cells

RIPK1 Protein, Mouse, Recombinant (His)

TMPH-02876

Species: Mouse

Expression System: E. coli

DR3/TNFRSF25 Protein, Mouse, Recombinant (His)

TMPK-00631

Species: Mouse

Expression System: HEK293 Cells

TNFR1/CD120a/TNFRSF1A Protein, Cynomolgus, Recombinant (His)

TMPK-00564

Species: Cynomolgus

Expression System: HEK293 Cells

APRIL/TNFSF13 Trimer Protein (Primary Amine Labeling), Human, Recombinant (His & Flag), Biotinylated

TMPK-00142

Species: Human

Expression System: HEK293 Cells

PAP Protein, Human, Recombinant (His)

TMPJ-01107

Species: Human

Expression System: E. coli

TNFAIP8 Protein, Human, Recombinant (His)

TMPY-03416

Species: Human

Expression System: E. coli

TXNDC17 Protein, Human, Recombinant (GST)

TMPH-02195

Species: Human

Expression System: E. coli

RELT/TNFRSF19L Protein, Human, Recombinant (hFc)

TMPJ-00272

Species: Human

Expression System: HEK293 Cells

MLKL Protein, Human, Recombinant (His)

TMPH-01695

Species: Human

Expression System: P. pastoris (Yeast)

TNFRSF19 Protein, Human, Recombinant (hFc)

TMPK-01203

Species: Human

Expression System: HEK293 Cells

MLKL Protein, Human, Recombinant (E. coli, His)

TMPH-01694

Species: Human

Expression System: E. coli

TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant (His & Avi)

TMPK-00276

Species: Human

Expression System: HEK293 Cells

HVEM Protein, Mouse, Recombinant (hFc)

TMPJ-00168

Species: Mouse

Expression System: HEK293 Cells

BCMA/TNFRSF17 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)

TMPK-00064

Species: Cynomolgus,Rhesus

Expression System: HEK293 Cells

CD27/TNFRSF7 Protein, Cynomolgus, Recombinant (His)

TMPK-00152

Species: Cynomolgus

Expression System: HEK293 Cells

FCMR/FAIM3 Protein, Mouse, Recombinant (His & SUMO)

TMPH-02650

Species: Mouse

Expression System: E. coli

TNF beta Protein, Mouse, Recombinant (His)

TMPH-02770

Species: Mouse

Expression System: E. coli

BCMA/TNFRSF17 Protein, Human, Recombinant (His & Flag)

TMPJ-00066

Species: Human

Expression System: HEK293 Cells

TL1A/TNFSF15 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)

TMPK-00489

Species: Cynomolgus,Rhesus

Expression System: HEK293 Cells

BCMA/TNFRSF17 Protein, Mouse, Recombinant (His & Avi)

TMPK-00071

Species: Mouse

Expression System: HEK293 Cells

BCMA/TNFRSF17 Trimer Protein, Human, Recombinant (His & Avi)

TMPK-00065

Species: Human

Expression System: HEK293 Cells

BCMA/TNFRSF17 Protein, Human, Recombinant (His & Avi), FITC-Labeled

TMPK-00066

Species: Human

Expression System: HEK293 Cells

BCMA/TNFRSF17 Trimer Protein, Human, Recombinant (His & Avi), Biotinylated

TMPK-00068

Species: Human

Expression System: HEK293 Cells

BCMA/TNFRSF17 Protein, Mouse, Recombinant (His & Avi), Biotinylated

TMPK-00072

Species: Mouse

Expression System: HEK293 Cells

LIGHT/TNFSF14 Trimer Protein, Human, Recombinant (His & Flag)

TMPK-00130

Species: Human

Expression System: HEK293 Cells

TL1A/TNFSF15 Trimer Protein, Human, Recombinant (His & Flag)

TMPK-00143

Species: Human

Expression System: HEK293 Cells

--------- More ---------

Cat No.	Product Name
L4700	Immunology/Inflammation Compound Library	4720 compounds
	A unique collection of 4720 anti-inflammation compounds effective for high throughput screening and high content screening.
L3800	NF-κB Signaling Compound Library	729 compounds
	A unique collection of 729 compounds targeting NF-κB signaling for high throughput screening and high content screening;
L9810	Anti-Fibrosis Compound Library	1155 compounds
	A unique collection of 1155 potential anti-fibrosis compounds, can be used in HTS and HCS;
L3600	Cytokine Inhibitor Library	604 compounds
	A unique collection of 604 compounds targeting cytokine signaling for high throughput screening and high content screening for drug discovery;
L9840	Anti-Alzheimer's Disease Compound Library	986 compounds
	A unique collection of 986 compounds with anti-AD activities or acting on main drug targets of AD can be used for HTS and HCS.

Libraries

Immunology/Inflammation Compound Library

L4700

Compounds: 4720

NF-κB Signaling Compound Library

L3800

Compounds: 729

Anti-Fibrosis Compound Library

L9810

Compounds: 1155

Cytokine Inhibitor Library

L3600

Compounds: 604

Anti-Alzheimer's Disease Compound Library

L9840

Compounds: 986