Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Methylguanidine (MG) is a guanidine compound deriving from protein catabolism. It is also a product of putrefaction. Methylguanidine is a suspected uraemic toxin that accumulates in renal failure, however it also exhibits anti-inflammatory effects. Methylguanidine is synthesized from creatinine concomitant with the synthesis of hydrogen peroxide from endogenous substrates in peroxisomes. Recent evidence suggests that methylguanidine significantly inhibits iNOS activity and TNF- release. This means that methylguandine can attenuate the degree of inflammation and tissue damage associated with endotoxic shock.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
500 mg | In stock | $ 41.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 55.00 |
Description | Methylguanidine (MG) is a guanidine compound deriving from protein catabolism. It is also a product of putrefaction. Methylguanidine is a suspected uraemic toxin that accumulates in renal failure, however it also exhibits anti-inflammatory effects. Methylguanidine is synthesized from creatinine concomitant with the synthesis of hydrogen peroxide from endogenous substrates in peroxisomes. Recent evidence suggests that methylguanidine significantly inhibits iNOS activity and TNF- release. This means that methylguandine can attenuate the degree of inflammation and tissue damage associated with endotoxic shock. |
Molecular Weight | 109.56 |
Formula | C2H8ClN3 |
CAS No. | 21770-81-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 200 mM
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1-Methylguanidine hydrochloride 21770-81-0 Metabolism Others Endogenous Metabolite 1 Methylguanidine hydrochloride 1-Methylguanidine inhibit 1-Methylguanidine Hydrochloride 1Methylguanidine hydrochloride Inhibitor inhibitor